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The map label for this gene is lpxP [H]

Identifier: 66043285

GI number: 66043285

Start: 15585

End: 16472

Strand: Direct

Name: lpxP [H]

Synonym: Psyr_0014

Alternate gene names: 66043285

Gene position: 15585-16472 (Clockwise)

Preceding gene: 66043284

Following gene: 66043291

Centisome position: 0.26

GC content: 61.26

Gene sequence:

>888_bases
GTGGATAAGTTCAAAGGCGCCGTAATGGTCGGGGCGTTGCGATTGTTTGCGCTGTTGCCATGGCGCGCGGTGCAGTGGAC
AGGCACCGCGATTGGCTGGCTGATGTGGAAGCTGCCCAACCGCTCGCGGGAAGTGGCGCGGATCAATCTGTCCAAGTGCT
TCCCCGAGTTGAGCGAGCCGGAGCTGGAAAAGCTCGTCGGCCGCAGCCTTATGGACATCGGCAAGACCTTGACCGAAAGC
GCCTGTGCGTGGATCTGGCCGGCACAGAAGTCGATCGACTTGGTGCGTGAAGTCGAAGGGCTCGATGTGCTCAAGGACGC
GCTGGCGTCCGGTAAGGGCGTGGTGGGTATCACCAGTCACCTGGGCAACTGGGAAGTGCTCAATCACTTCTACTGCAGCC
AGTGCAAGCCGATCATTTTCTATCGTCCACCCAAGCTGAAAGCCGTGGACGACCTGTTGCGCAAGCAGCGTGTGCAGTTG
GGCAACCGGGTGGCGGCGTCGACCAAGGAAGGCATTCTCAGTGTCATCAAGGAAGTGCGCAAAGGCGGCTCGGTGGGTAT
TCCGGCCGATCCGGAGCCGGCCGAATCAGCCGGTATCTTCGTGCCCTTCTGCGGCACCATGGCCCTGACCAGCAAGTTTG
TGCCGAACATGCTGGCAGGCGGCAAGGCAGTCGGCGTCTTCCTGCACGCCATGCGCCTGCCGGACGGCTCGGGTTATAAA
GTGGTACTCGAAGCGGCCCCGGAAGCGATGTACAGCACCGACACCGAAACCTCGGCAGCGGCGATGAGCAAAGTGGTCGA
GAAATACGTGCGGGCGTACCCGAGCCAGTACATGTGGACCATGAAGCGCTTCAAGAAACGCCCGCCAGGTGAGGCGCGCT
GGTACTAG

Upstream 100 bases:

>100_bases
CCAGCGGCATGGTCATGGACCACACTGTCGATTGCGATCGGTATGCGATCCTGAGCCGCTGACGGTTACACTACCCGCCT
CGAGAATCTGGGAGTCATCT

Downstream 100 bases:

>100_bases
AAAGGACCGGACGCGGAGCGTCCGCAACGGCGTGTCCACGCTGGAGCATGGGCACGATCGTGTTCCTGCAGACACCTATC
GTTCCTCACGCTCCGCGTGG

Product: lipid A biosynthesis lauroyl acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MDKFKGAVMVGALRLFALLPWRAVQWTGTAIGWLMWKLPNRSREVARINLSKCFPELSEPELEKLVGRSLMDIGKTLTES
ACAWIWPAQKSIDLVREVEGLDVLKDALASGKGVVGITSHLGNWEVLNHFYCSQCKPIIFYRPPKLKAVDDLLRKQRVQL
GNRVAASTKEGILSVIKEVRKGGSVGIPADPEPAESAGIFVPFCGTMALTSKFVPNMLAGGKAVGVFLHAMRLPDGSGYK
VVLEAAPEAMYSTDTETSAAAMSKVVEKYVRAYPSQYMWTMKRFKKRPPGEARWY

Sequences:

>Translated_295_residues
MDKFKGAVMVGALRLFALLPWRAVQWTGTAIGWLMWKLPNRSREVARINLSKCFPELSEPELEKLVGRSLMDIGKTLTES
ACAWIWPAQKSIDLVREVEGLDVLKDALASGKGVVGITSHLGNWEVLNHFYCSQCKPIIFYRPPKLKAVDDLLRKQRVQL
GNRVAASTKEGILSVIKEVRKGGSVGIPADPEPAESAGIFVPFCGTMALTSKFVPNMLAGGKAVGVFLHAMRLPDGSGYK
VVLEAAPEAMYSTDTETSAAAMSKVVEKYVRAYPSQYMWTMKRFKKRPPGEARWY
>Mature_295_residues
MDKFKGAVMVGALRLFALLPWRAVQWTGTAIGWLMWKLPNRSREVARINLSKCFPELSEPELEKLVGRSLMDIGKTLTES
ACAWIWPAQKSIDLVREVEGLDVLKDALASGKGVVGITSHLGNWEVLNHFYCSQCKPIIFYRPPKLKAVDDLLRKQRVQL
GNRVAASTKEGILSVIKEVRKGGSVGIPADPEPAESAGIFVPFCGTMALTSKFVPNMLAGGKAVGVFLHAMRLPDGSGYK
VVLEAAPEAMYSTDTETSAAAMSKVVEKYVRAYPSQYMWTMKRFKKRPPGEARWY

Specific function: Unknown

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI87082094, Length=290, Percent_Identity=30.3448275862069, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1787292, Length=282, Percent_Identity=31.2056737588652, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788161, Length=289, Percent_Identity=25.6055363321799, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011920 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 32652; Mature: 32652

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKFKGAVMVGALRLFALLPWRAVQWTGTAIGWLMWKLPNRSREVARINLSKCFPELSEP
CCCHHHHHHHHHHHHHHHCCCHHEEECCHHHHHHHHHCCCCCHHHHEEEHHHHCCCCCCH
ELEKLVGRSLMDIGKTLTESACAWIWPAQKSIDLVREVEGLDVLKDALASGKGVVGITSH
HHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
LGNWEVLNHFYCSQCKPIIFYRPPKLKAVDDLLRKQRVQLGNRVAASTKEGILSVIKEVR
CCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGGSVGIPADPEPAESAGIFVPFCGTMALTSKFVPNMLAGGKAVGVFLHAMRLPDGSGYK
CCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCE
VVLEAAPEAMYSTDTETSAAAMSKVVEKYVRAYPSQYMWTMKRFKKRPPGEARWY
EEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MDKFKGAVMVGALRLFALLPWRAVQWTGTAIGWLMWKLPNRSREVARINLSKCFPELSEP
CCCHHHHHHHHHHHHHHHCCCHHEEECCHHHHHHHHHCCCCCHHHHEEEHHHHCCCCCCH
ELEKLVGRSLMDIGKTLTESACAWIWPAQKSIDLVREVEGLDVLKDALASGKGVVGITSH
HHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
LGNWEVLNHFYCSQCKPIIFYRPPKLKAVDDLLRKQRVQLGNRVAASTKEGILSVIKEVR
CCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGGSVGIPADPEPAESAGIFVPFCGTMALTSKFVPNMLAGGKAVGVFLHAMRLPDGSGYK
CCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCE
VVLEAAPEAMYSTDTETSAAAMSKVVEKYVRAYPSQYMWTMKRFKKRPPGEARWY
EEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]