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The map label for this gene is plsC [H]

Identifier: 66043280

GI number: 66043280

Start: 10525

End: 11295

Strand: Reverse

Name: plsC [H]

Synonym: Psyr_0009

Alternate gene names: 66043280

Gene position: 11295-10525 (Counterclockwise)

Preceding gene: 66043281

Following gene: 66043278

Centisome position: 0.19

GC content: 57.98

Gene sequence:

>771_bases
ATGTCGATCATGCAGGCAATCAGGACCTTCTTCTTTTACCTGTTGCTGGGCACCAGCTCGCTGCTGTGGTGCACATTGAG
TTTTTTCATTGCGCCTTTTCTGCCGTTCAAAGCCCGCTATCGCTTCATCAACGTCTACTGGTGCCGCTGCGCCATCTGGC
TGACCAAGGTGTTTCTGAACATCAAGGTTGAAGTAACTGGCGCCGAGAACGTACCGAAAACCCCCTGCGTGATCATCTCC
AACCATCAGAGCACCTGGGAGACCTTCTTTCTGTCGGCGTATTTCGAGCCGATGAGTCAGGTCCTCAAGCGTGAACTGCT
GTACGTGCCGTTCTTTGGCTGGGCGATGGCAATGCTGCGCCCGATCGCTATCGACCGCGAAAACCCGAAAGCCGCACTCA
GGGAGATTGCCAAGAAGGGCGACGAGCTGCTCAAGGATGGCGTCTGGGTGTTGATCTTCCCGGAGGGCACACGCGTGCCT
TACGGCCAGGTCGGCAAATTCTCACGCGGTGGAACTGCACTGGCAGTGAACGCCGACCTGCCCGTGCTGCCTGTCGCGCA
CAACGCAGGCAAGTATTGGCCTCGCGACGGCTGGGCGAAAAAGCCAGGTACCATTCAGGTGGTGATCGGCGAGCCGATGT
ATGCAGAAGGCACAGGCCCACGTGCCATTGCTGCGTTGAATGAGCGTGTGCAGGCCTGGAATGAAGACACACAACGCGCA
ATGGGTTCGCCTGTCGAGCCTGCAGCCACCCCCGAAAAAGTCCCGGCGTGA

Upstream 100 bases:

>100_bases
TTGCCGCAGAACTTATCCACAACAGCACTCACTGAACAATCAGCTCTTCAGGTTCAGGACGCTCAAGGAGCGGGCACCTG
CCCGTACGGTAAACGTAACT

Downstream 100 bases:

>100_bases
TTTTGTGGATAACCTGTGTACGGTTTTTCTGAAATCGCTGAAAAAGACTGTCTAACCTGTTAATTCGTATACATATTTTT
TCAGGCTATAAAAACCGGAA

Product: phospholipid/glycerol acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MSIMQAIRTFFFYLLLGTSSLLWCTLSFFIAPFLPFKARYRFINVYWCRCAIWLTKVFLNIKVEVTGAENVPKTPCVIIS
NHQSTWETFFLSAYFEPMSQVLKRELLYVPFFGWAMAMLRPIAIDRENPKAALREIAKKGDELLKDGVWVLIFPEGTRVP
YGQVGKFSRGGTALAVNADLPVLPVAHNAGKYWPRDGWAKKPGTIQVVIGEPMYAEGTGPRAIAALNERVQAWNEDTQRA
MGSPVEPAATPEKVPA

Sequences:

>Translated_256_residues
MSIMQAIRTFFFYLLLGTSSLLWCTLSFFIAPFLPFKARYRFINVYWCRCAIWLTKVFLNIKVEVTGAENVPKTPCVIIS
NHQSTWETFFLSAYFEPMSQVLKRELLYVPFFGWAMAMLRPIAIDRENPKAALREIAKKGDELLKDGVWVLIFPEGTRVP
YGQVGKFSRGGTALAVNADLPVLPVAHNAGKYWPRDGWAKKPGTIQVVIGEPMYAEGTGPRAIAALNERVQAWNEDTQRA
MGSPVEPAATPEKVPA
>Mature_255_residues
SIMQAIRTFFFYLLLGTSSLLWCTLSFFIAPFLPFKARYRFINVYWCRCAIWLTKVFLNIKVEVTGAENVPKTPCVIISN
HQSTWETFFLSAYFEPMSQVLKRELLYVPFFGWAMAMLRPIAIDRENPKAALREIAKKGDELLKDGVWVLIFPEGTRVPY
GQVGKFSRGGTALAVNADLPVLPVAHNAGKYWPRDGWAKKPGTIQVVIGEPMYAEGTGPRAIAALNERVQAWNEDTQRAM
GSPVEPAATPEKVPA

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=195, Percent_Identity=32.3076923076923, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI15100175, Length=195, Percent_Identity=32.3076923076923, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI6041665, Length=207, Percent_Identity=28.0193236714976, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17564032, Length=161, Percent_Identity=31.055900621118, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6320151, Length=260, Percent_Identity=29.6153846153846, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24641614, Length=196, Percent_Identity=28.0612244897959, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24641612, Length=196, Percent_Identity=28.0612244897959, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI281364648, Length=231, Percent_Identity=26.4069264069264, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24582856, Length=231, Percent_Identity=26.4069264069264, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24582854, Length=231, Percent_Identity=26.4069264069264, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 28779; Mature: 28648

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIMQAIRTFFFYLLLGTSSLLWCTLSFFIAPFLPFKARYRFINVYWCRCAIWLTKVFLN
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHEEEHHHHHHHHHHHHHHHHE
IKVEVTGAENVPKTPCVIISNHQSTWETFFLSAYFEPMSQVLKRELLYVPFFGWAMAMLR
EEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
PIAIDRENPKAALREIAKKGDELLKDGVWVLIFPEGTRVPYGQVGKFSRGGTALAVNADL
HHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCC
PVLPVAHNAGKYWPRDGWAKKPGTIQVVIGEPMYAEGTGPRAIAALNERVQAWNEDTQRA
CEEEEECCCCCCCCCCCCCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHCCHHHHHH
MGSPVEPAATPEKVPA
CCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SIMQAIRTFFFYLLLGTSSLLWCTLSFFIAPFLPFKARYRFINVYWCRCAIWLTKVFLN
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHEEEHHHHHHHHHHHHHHHHE
IKVEVTGAENVPKTPCVIISNHQSTWETFFLSAYFEPMSQVLKRELLYVPFFGWAMAMLR
EEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
PIAIDRENPKAALREIAKKGDELLKDGVWVLIFPEGTRVPYGQVGKFSRGGTALAVNADL
HHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCC
PVLPVAHNAGKYWPRDGWAKKPGTIQVVIGEPMYAEGTGPRAIAALNERVQAWNEDTQRA
CEEEEECCCCCCCCCCCCCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHCCHHHHHH
MGSPVEPAATPEKVPA
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]