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The map label for this gene is cmt2 [H]

Identifier: 62391716

GI number: 62391716

Start: 3048843

End: 3049868

Strand: Reverse

Name: cmt2 [H]

Synonym: cg3186

Alternate gene names: 62391716

Gene position: 3049868-3048843 (Counterclockwise)

Preceding gene: 62391717

Following gene: 62391714

Centisome position: 92.91

GC content: 56.24

Gene sequence:

>1026_bases
ATGTCCGTATTTACACGAGCTGGCGAGGCAAGCCGTAAGCTCGTCGCCCTTGTAGTGGCTCTTGCCACCGCGGCAGCCCT
CATGGTTGTTGGACAAGGCACCGCACAAGCTGCAAACCGTGACTGGTTGCGCGCAGATAACTCTGGTTACTGTGACTGGG
ATGCTGTGGGCTTCTGGGTTCAGCGCTGTGATGTTTGGTCGCCTGCAATGGGCCGCAACATTCCTGTCCAGATCCAGCCT
GCAGGGCGTGGCGGAAACGCTGGCCTGTACCTGCTCGATGGTATGCGCGCTACTGAGTACTCAAACGCATGGCTCGTGGA
TACCAACGCTGCGCGCCTCTACGCACCAAACAACATCACCCTCGTGATGCCAGTTGGTGGCGCAGGTTCCTTCTATGCTG
ACTGGAACTCCCAGGCATCTCTTTCCTCCTCCGATCCTGTCATCTACATGTGGGAGACTTTCCTTACCCAGGAATTGCCT
GCATACCTTGAGCAGAACTTCGGCGTTGCGCGAAACAACAACTCCATTGGTGGCCTGTCCATGGGCGGAACTGCCGCGCT
GAACCTCGCAGCAAAGCACCCAGATCAGTTCCGCCAGGCTATGTCTTGGTCCGGCTACTTGAACACCACTGCACCAGGCA
TGCAAACCCTGCTGCGTCTGGCCATGCTGGACACCGGTGGATTCAACGTCAACGCAATGTATGGCTCAATCATTAACCCA
CGTCGTTTTGAAAACGACCCATTCTGGAACATGGGCGGCTTGGCTAACACCGACGTCTACATCTCTGCAGCTTCCGGCCT
GTGGAGCCCTCAGGATGATGGAGTTCGCGTAGACCACCGCCTCACTGGTTCTGTGCTTGAATTCGTGGCAATGACATCCA
CCAGGATTTGGGAAGCAAAGGCAAGGCTTCAGGGTCTGAACCCAACTGCGGATTACCCAATGTATGGCATTCACGGCTGG
GCTCAGTTCAACTCCCAGCTGGAGAGAACTCAGGGTCGTGTTCTAGACGTCATGAACGCCTGGTAG

Upstream 100 bases:

>100_bases
AACTTGGTAACGTGTGGGCGGAAAAACAAGATAGGCATCGAGAGGTATCAGCGGTCCATACCGCCGATGGGTACATATCA
ATTTTTGCCGGAGGAGAATT

Downstream 100 bases:

>100_bases
AGCCACACCAAAGGCCACACCAAAGGCCACACCAAAATCAAAAGCCCACTGTACTATTGCAGTGGGCTTTTTGGCGCGCT
AAAAACTTAGGTCCTGGCCT

Product: trehalose corynomycolyl transferase

Products: NA

Alternate protein names: Antigen 85 complex C; 85C; Ag85C; Fibronectin-binding protein C; Mycolyl transferase 85C [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSVFTRAGEASRKLVALVVALATAAALMVVGQGTAQAANRDWLRADNSGYCDWDAVGFWVQRCDVWSPAMGRNIPVQIQP
AGRGGNAGLYLLDGMRATEYSNAWLVDTNAARLYAPNNITLVMPVGGAGSFYADWNSQASLSSSDPVIYMWETFLTQELP
AYLEQNFGVARNNNSIGGLSMGGTAALNLAAKHPDQFRQAMSWSGYLNTTAPGMQTLLRLAMLDTGGFNVNAMYGSIINP
RRFENDPFWNMGGLANTDVYISAASGLWSPQDDGVRVDHRLTGSVLEFVAMTSTRIWEAKARLQGLNPTADYPMYGIHGW
AQFNSQLERTQGRVLDVMNAW

Sequences:

>Translated_341_residues
MSVFTRAGEASRKLVALVVALATAAALMVVGQGTAQAANRDWLRADNSGYCDWDAVGFWVQRCDVWSPAMGRNIPVQIQP
AGRGGNAGLYLLDGMRATEYSNAWLVDTNAARLYAPNNITLVMPVGGAGSFYADWNSQASLSSSDPVIYMWETFLTQELP
AYLEQNFGVARNNNSIGGLSMGGTAALNLAAKHPDQFRQAMSWSGYLNTTAPGMQTLLRLAMLDTGGFNVNAMYGSIINP
RRFENDPFWNMGGLANTDVYISAASGLWSPQDDGVRVDHRLTGSVLEFVAMTSTRIWEAKARLQGLNPTADYPMYGIHGW
AQFNSQLERTQGRVLDVMNAW
>Mature_340_residues
SVFTRAGEASRKLVALVVALATAAALMVVGQGTAQAANRDWLRADNSGYCDWDAVGFWVQRCDVWSPAMGRNIPVQIQPA
GRGGNAGLYLLDGMRATEYSNAWLVDTNAARLYAPNNITLVMPVGGAGSFYADWNSQASLSSSDPVIYMWETFLTQELPA
YLEQNFGVARNNNSIGGLSMGGTAALNLAAKHPDQFRQAMSWSGYLNTTAPGMQTLLRLAMLDTGGFNVNAMYGSIINPR
RFENDPFWNMGGLANTDVYISAASGLWSPQDDGVRVDHRLTGSVLEFVAMTSTRIWEAKARLQGLNPTADYPMYGIHGWA
QFNSQLERTQGRVLDVMNAW

Specific function: Proteins of the antigen 85 complex are responsible for the high affinity of mycobacteria to fibronectin. Possesses a mycolyltransferase activity required for the biogenesis of trehalose dimycolate (cord factor), a dominant structure necessary for maintain

COG id: COG0627

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial A85 antigen family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: NA

Molecular weight: Translated: 37187; Mature: 37056

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVFTRAGEASRKLVALVVALATAAALMVVGQGTAQAANRDWLRADNSGYCDWDAVGFWV
CCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCHHHCCCCCEECCCCCCCCHHHHHHHH
QRCDVWSPAMGRNIPVQIQPAGRGGNAGLYLLDGMRATEYSNAWLVDTNAARLYAPNNIT
HHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCEEEEECCCEEEECCCCEE
LVMPVGGAGSFYADWNSQASLSSSDPVIYMWETFLTQELPAYLEQNFGVARNNNSIGGLS
EEEECCCCCCEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCEEECCCCCCCEE
MGGTAALNLAAKHPDQFRQAMSWSGYLNTTAPGMQTLLRLAMLDTGGFNVNAMYGSIINP
CCCHHEEEEHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCC
RRFENDPFWNMGGLANTDVYISAASGLWSPQDDGVRVDHRLTGSVLEFVAMTSTRIWEAK
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHH
ARLQGLNPTADYPMYGIHGWAQFNSQLERTQGRVLDVMNAW
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEHHHCCC
>Mature Secondary Structure 
SVFTRAGEASRKLVALVVALATAAALMVVGQGTAQAANRDWLRADNSGYCDWDAVGFWV
CCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCHHHCCCCCEECCCCCCCCHHHHHHHH
QRCDVWSPAMGRNIPVQIQPAGRGGNAGLYLLDGMRATEYSNAWLVDTNAARLYAPNNIT
HHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCEEEEECCCEEEECCCCEE
LVMPVGGAGSFYADWNSQASLSSSDPVIYMWETFLTQELPAYLEQNFGVARNNNSIGGLS
EEEECCCCCCEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCEEECCCCCCCEE
MGGTAALNLAAKHPDQFRQAMSWSGYLNTTAPGMQTLLRLAMLDTGGFNVNAMYGSIINP
CCCHHEEEEHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCC
RRFENDPFWNMGGLANTDVYISAASGLWSPQDDGVRVDHRLTGSVLEFVAMTSTRIWEAK
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHH
ARLQGLNPTADYPMYGIHGWAQFNSQLERTQGRVLDVMNAW
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8359887; 11234002 [H]