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The map label for this gene is pck [H]

Identifier: 62391702

GI number: 62391702

Start: 3025365

End: 3027197

Strand: Reverse

Name: pck [H]

Synonym: cg3169

Alternate gene names: 62391702

Gene position: 3027197-3025365 (Counterclockwise)

Preceding gene: 62391709

Following gene: 62391699

Centisome position: 92.22

GC content: 57.67

Gene sequence:

>1833_bases
ATGACTACTGCTGCAATCAGGGGCCTTCAGGGCGAGGCGCCGACCAAGAATAAGGAACTGCTGAACTGGATCGCAGACGC
CGTCGAGCTCTTCCAGCCTGAGGCTGTTGTGTTCGTTGATGGATCCCAGGCTGAGTGGGATCGCATGGCGGAGGATCTTG
TTGAAGCCGGTACCCTCATCAAGCTCAACGAGGAAAAGCGTCCGAACAGCTACCTAGCTCGTTCCAACCCATCTGACGTT
GCGCGCGTTGAGTCCCGCACCTTCATCTGCTCCGAGAAGGAAGAAGATGCTGGCCCAACCAACAACTGGGCTCCACCACA
GGCAATGAAGGACGAAATGTCCAAGCATTACGCTGGTTCCATGAAGGGGCGCACCATGTACGTCGTGCCTTTCTGCATGG
GTCCAATCAGCGATCCGGACCCTAAGCTTGGTGTGCAGCTCACTGACTCCGAGTACGTTGTCATGTCCATGCGCATCATG
ACCCGCATGGGTATTGAAGCGCTGGACAAGATCGGCGCGAACGGCAGCTTCGTCAGGTGCCTCCACTCCGTTGGTGCTCC
TTTGGAGCCAGGCCAGGAAGACGTTGCATGGCCTTGCAACGACACCAAGTACATCACCCAGTTCCCAGAGACCAAGGAAA
TTTGGTCCTACGGTTCCGGCTACGGCGGAAACGCAATCCTGGCAAAGAAGTGCTACGCACTGCGTATCGCATCTGTCATG
GCTCGCGAAGAAGGATGGATGGCTGAGCACATGCTCATCCTGAAGCTGATCAACCCAGAGGGCAAGGCGTACCACATCGC
AGCAGCATTCCCATCTGCTTGTGGCAAGACCAACCTCGCCATGATCACTCCAACCATCCCAGGCTGGACCGCTCAGGTTG
TTGGCGACGACATCGCTTGGCTGAAGCTGCGCGAGGACGGCCTCTACGCAGTTAACCCAGAAAATGGTTTCTTCGGTGTT
GCTCCAGGCACCAACTACGCATCCAACCCAATCGCGATGAAGACCATGGAACCAGGCAACACCCTGTTCACCAACGTGGC
ACTCACCGACGACGGCGACATCTGGTGGGAAGGCATGGACGGCGACGCCCCAGCTCACCTCATTGACTGGATGGGCAACG
ACTGGACCCCAGAGTCCGACGAAAACGCTGCTCACCCTAACTCCCGTTACTGCGTAGCAATCGACCAGTCCCCAGCAGCA
GCACCTGAGTTCAACGACTGGGAAGGCGTCAAGATCGACGCAATCCTCTTCGGTGGACGTCGCGCAGACACCGTCCCACT
GGTTACCCAGACCTACGACTGGGAGCACGGCACCATGGTTGGTGCACTGCTCGCATCCGGTCAGACCGCAGCTTCCGCAG
AAGCAAAGGTCGGCACACTCCGCCACGACCCAATGGCAATGCTCCCATTCATTGGCTACAACGCTGGTGAATACCTGCAG
AACTGGATTGACATGGGTAACAAGGGTGGCGACAAGATGCCATCCATCTTCCTGGTCAACTGGTTCCGCCGTGGCGAAGA
TGGACGCTTCCTGTGGCCTGGCTTCGGCGACAACTCTCGCGTTCTGAAGTGGGTCATCGACCGCATCGAAGGCCACGTTG
GCGCAGACGAGACCGTTGTTGGACACACCGCTAAGGCCGAAGACCTCGACCTCGACGGCCTCGACACCCCAATTGAGGAT
GTCAAGGAAGCACTGACCGCTCCTGCAGAGCAGTGGGCAAACGACGTTGAAGACAACGCCGAGTACCTCACTTTCCTCGG
ACCACGTGTTCCTGCAGAGGTTCACAGCCAGTTCGATGCTCTGAAGGCCCGCATTTCAGCAGCTCACGCTTAA

Upstream 100 bases:

>100_bases
ATGTGTCCGTTGTCTCACCTAAAGTTTTAACTAGTTCTGTATCTGAAAGCTACGCTAGGGGGCGAGAACTCTGTCGAATG
ACACAAAATCTGGAGAAGTA

Downstream 100 bases:

>100_bases
AGTTCACGCTTAAGAACTGCTAAATAACAAGAAAGGCTCCCACCGAAAGTGGGAGCCTTTCTTGTCGTTAAGCGATGAAT
TCCTCAAAACCTCAGTGCTT

Product: phosphoenolpyruvate carboxykinase

Products: NA

Alternate protein names: PEP carboxykinase; PEPCK; Phosphoenolpyruvate carboxylase [H]

Number of amino acids: Translated: 610; Mature: 609

Protein sequence:

>610_residues
MTTAAIRGLQGEAPTKNKELLNWIADAVELFQPEAVVFVDGSQAEWDRMAEDLVEAGTLIKLNEEKRPNSYLARSNPSDV
ARVESRTFICSEKEEDAGPTNNWAPPQAMKDEMSKHYAGSMKGRTMYVVPFCMGPISDPDPKLGVQLTDSEYVVMSMRIM
TRMGIEALDKIGANGSFVRCLHSVGAPLEPGQEDVAWPCNDTKYITQFPETKEIWSYGSGYGGNAILAKKCYALRIASVM
AREEGWMAEHMLILKLINPEGKAYHIAAAFPSACGKTNLAMITPTIPGWTAQVVGDDIAWLKLREDGLYAVNPENGFFGV
APGTNYASNPIAMKTMEPGNTLFTNVALTDDGDIWWEGMDGDAPAHLIDWMGNDWTPESDENAAHPNSRYCVAIDQSPAA
APEFNDWEGVKIDAILFGGRRADTVPLVTQTYDWEHGTMVGALLASGQTAASAEAKVGTLRHDPMAMLPFIGYNAGEYLQ
NWIDMGNKGGDKMPSIFLVNWFRRGEDGRFLWPGFGDNSRVLKWVIDRIEGHVGADETVVGHTAKAEDLDLDGLDTPIED
VKEALTAPAEQWANDVEDNAEYLTFLGPRVPAEVHSQFDALKARISAAHA

Sequences:

>Translated_610_residues
MTTAAIRGLQGEAPTKNKELLNWIADAVELFQPEAVVFVDGSQAEWDRMAEDLVEAGTLIKLNEEKRPNSYLARSNPSDV
ARVESRTFICSEKEEDAGPTNNWAPPQAMKDEMSKHYAGSMKGRTMYVVPFCMGPISDPDPKLGVQLTDSEYVVMSMRIM
TRMGIEALDKIGANGSFVRCLHSVGAPLEPGQEDVAWPCNDTKYITQFPETKEIWSYGSGYGGNAILAKKCYALRIASVM
AREEGWMAEHMLILKLINPEGKAYHIAAAFPSACGKTNLAMITPTIPGWTAQVVGDDIAWLKLREDGLYAVNPENGFFGV
APGTNYASNPIAMKTMEPGNTLFTNVALTDDGDIWWEGMDGDAPAHLIDWMGNDWTPESDENAAHPNSRYCVAIDQSPAA
APEFNDWEGVKIDAILFGGRRADTVPLVTQTYDWEHGTMVGALLASGQTAASAEAKVGTLRHDPMAMLPFIGYNAGEYLQ
NWIDMGNKGGDKMPSIFLVNWFRRGEDGRFLWPGFGDNSRVLKWVIDRIEGHVGADETVVGHTAKAEDLDLDGLDTPIED
VKEALTAPAEQWANDVEDNAEYLTFLGPRVPAEVHSQFDALKARISAAHA
>Mature_609_residues
TTAAIRGLQGEAPTKNKELLNWIADAVELFQPEAVVFVDGSQAEWDRMAEDLVEAGTLIKLNEEKRPNSYLARSNPSDVA
RVESRTFICSEKEEDAGPTNNWAPPQAMKDEMSKHYAGSMKGRTMYVVPFCMGPISDPDPKLGVQLTDSEYVVMSMRIMT
RMGIEALDKIGANGSFVRCLHSVGAPLEPGQEDVAWPCNDTKYITQFPETKEIWSYGSGYGGNAILAKKCYALRIASVMA
REEGWMAEHMLILKLINPEGKAYHIAAAFPSACGKTNLAMITPTIPGWTAQVVGDDIAWLKLREDGLYAVNPENGFFGVA
PGTNYASNPIAMKTMEPGNTLFTNVALTDDGDIWWEGMDGDAPAHLIDWMGNDWTPESDENAAHPNSRYCVAIDQSPAAA
PEFNDWEGVKIDAILFGGRRADTVPLVTQTYDWEHGTMVGALLASGQTAASAEAKVGTLRHDPMAMLPFIGYNAGEYLQN
WIDMGNKGGDKMPSIFLVNWFRRGEDGRFLWPGFGDNSRVLKWVIDRIEGHVGADETVVGHTAKAEDLDLDGLDTPIEDV
KEALTAPAEQWANDVEDNAEYLTFLGPRVPAEVHSQFDALKARISAAHA

Specific function: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle [H]

COG id: COG1274

COG function: function code C; Phosphoenolpyruvate carboxykinase (GTP)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family [H]

Homologues:

Organism=Homo sapiens, GI66346721, Length=619, Percent_Identity=47.9806138933764, Blast_Score=565, Evalue=1e-161,
Organism=Homo sapiens, GI187281517, Length=613, Percent_Identity=46.6557911908646, Blast_Score=554, Evalue=1e-157,
Organism=Homo sapiens, GI66346723, Length=411, Percent_Identity=47.4452554744526, Blast_Score=367, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17555492, Length=626, Percent_Identity=46.4856230031949, Blast_Score=552, Evalue=1e-157,
Organism=Caenorhabditis elegans, GI71989645, Length=617, Percent_Identity=45.8670988654781, Blast_Score=540, Evalue=1e-154,
Organism=Caenorhabditis elegans, GI71989658, Length=617, Percent_Identity=45.8670988654781, Blast_Score=539, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI71989653, Length=595, Percent_Identity=46.5546218487395, Blast_Score=531, Evalue=1e-151,
Organism=Caenorhabditis elegans, GI32564411, Length=556, Percent_Identity=48.7410071942446, Blast_Score=523, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI32564407, Length=524, Percent_Identity=49.618320610687, Blast_Score=501, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI71989649, Length=516, Percent_Identity=46.8992248062016, Blast_Score=473, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI32564409, Length=370, Percent_Identity=47.8378378378378, Blast_Score=335, Evalue=4e-92,
Organism=Caenorhabditis elegans, GI17540956, Length=334, Percent_Identity=27.2455089820359, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24655085, Length=597, Percent_Identity=48.4087102177554, Blast_Score=573, Evalue=1e-163,
Organism=Drosophila melanogaster, GI24655082, Length=611, Percent_Identity=47.4631751227496, Blast_Score=561, Evalue=1e-160,
Organism=Drosophila melanogaster, GI161077226, Length=569, Percent_Identity=48.8576449912127, Blast_Score=540, Evalue=1e-153,
Organism=Drosophila melanogaster, GI24655088, Length=502, Percent_Identity=49.601593625498, Blast_Score=503, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018091
- InterPro:   IPR013035
- InterPro:   IPR008209
- InterPro:   IPR008210 [H]

Pfam domain/function: PF00821 PEPCK [H]

EC number: =4.1.1.32 [H]

Molecular weight: Translated: 66875; Mature: 66744

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00505 PEPCK_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAAIRGLQGEAPTKNKELLNWIADAVELFQPEAVVFVDGSQAEWDRMAEDLVEAGTLI
CCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCEE
KLNEEKRPNSYLARSNPSDVARVESRTFICSEKEEDAGPTNNWAPPQAMKDEMSKHYAGS
EECCCCCCCCCCCCCCCHHHHHHCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
MKGRTMYVVPFCMGPISDPDPKLGVQLTDSEYVVMSMRIMTRMGIEALDKIGANGSFVRC
CCCCEEEEEEEECCCCCCCCCCCCEEECCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHH
LHSVGAPLEPGQEDVAWPCNDTKYITQFPETKEIWSYGSGYGGNAILAKKCYALRIASVM
HHHCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
AREEGWMAEHMLILKLINPEGKAYHIAAAFPSACGKTNLAMITPTIPGWTAQVVGDDIAW
HHHCCCHHHEEEEEEEECCCCCEEEEEEECCCCCCCCCEEEEECCCCCCEEEECCCCEEE
LKLREDGLYAVNPENGFFGVAPGTNYASNPIAMKTMEPGNTLFTNVALTDDGDIWWEGMD
EEEECCCEEEECCCCCEEECCCCCCCCCCCEEEEEECCCCEEEEEEEEECCCCEEEECCC
GDAPAHLIDWMGNDWTPESDENAAHPNSRYCVAIDQSPAAAPEFNDWEGVKIDAILFGGR
CCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECCC
RADTVPLVTQTYDWEHGTMVGALLASGQTAASAEAKVGTLRHDPMAMLPFIGYNAGEYLQ
CCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHH
NWIDMGNKGGDKMPSIFLVNWFRRGEDGRFLWPGFGDNSRVLKWVIDRIEGHVGADETVV
HHHHCCCCCCCCCCEEEEEEHHHCCCCCCEECCCCCCCHHHHHHHHHHHHCCCCCCCEEE
GHTAKAEDLDLDGLDTPIEDVKEALTAPAEQWANDVEDNAEYLTFLGPRVPAEVHSQFDA
CCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHH
LKARISAAHA
HHHHHHHCCC
>Mature Secondary Structure 
TTAAIRGLQGEAPTKNKELLNWIADAVELFQPEAVVFVDGSQAEWDRMAEDLVEAGTLI
CCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCEE
KLNEEKRPNSYLARSNPSDVARVESRTFICSEKEEDAGPTNNWAPPQAMKDEMSKHYAGS
EECCCCCCCCCCCCCCCHHHHHHCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
MKGRTMYVVPFCMGPISDPDPKLGVQLTDSEYVVMSMRIMTRMGIEALDKIGANGSFVRC
CCCCEEEEEEEECCCCCCCCCCCCEEECCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHH
LHSVGAPLEPGQEDVAWPCNDTKYITQFPETKEIWSYGSGYGGNAILAKKCYALRIASVM
HHHCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
AREEGWMAEHMLILKLINPEGKAYHIAAAFPSACGKTNLAMITPTIPGWTAQVVGDDIAW
HHHCCCHHHEEEEEEEECCCCCEEEEEEECCCCCCCCCEEEEECCCCCCEEEECCCCEEE
LKLREDGLYAVNPENGFFGVAPGTNYASNPIAMKTMEPGNTLFTNVALTDDGDIWWEGMD
EEEECCCEEEECCCCCEEECCCCCCCCCCCEEEEEECCCCEEEEEEEEECCCCEEEECCC
GDAPAHLIDWMGNDWTPESDENAAHPNSRYCVAIDQSPAAAPEFNDWEGVKIDAILFGGR
CCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECCC
RADTVPLVTQTYDWEHGTMVGALLASGQTAASAEAKVGTLRHDPMAMLPFIGYNAGEYLQ
CCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHH
NWIDMGNKGGDKMPSIFLVNWFRRGEDGRFLWPGFGDNSRVLKWVIDRIEGHVGADETVV
HHHHCCCCCCCCCCEEEEEEHHHCCCCCCEECCCCCCCHHHHHHHHHHHHCCCCCCCEEE
GHTAKAEDLDLDGLDTPIEDVKEALTAPAEQWANDVEDNAEYLTFLGPRVPAEVHSQFDA
CCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHH
LKARISAAHA
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12840036 [H]