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The map label for this gene is hmp [H]

Identifier: 62391676

GI number: 62391676

Start: 2999445

End: 3000605

Strand: Reverse

Name: hmp [H]

Synonym: cg3141

Alternate gene names: 62391676

Gene position: 3000605-2999445 (Counterclockwise)

Preceding gene: 62391679

Following gene: 62391672

Centisome position: 91.41

GC content: 56.85

Gene sequence:

>1161_bases
TTGATCGTTTCCACCCAGCCCATTACTGATCGCAGCGCACTCTCGGCAGAACACGCAGAGGTGATCAAAGCAACGCTTCC
TCTCGTGGGCGGCAAGATTAATGAGATCACGCCGGTTTTCTACAACAAGATGTTTGCGGCTCACCCAGAATTGATCGCTA
ACACCTTCAACCGTGGCAATCAGAAGCAAGGCGATCAGCAGAAGGCGCTGGCGGCTTCGATTGCAACGTTTGCCACCATG
CTCGTTACTCCTGATGCTCCTGACCCAGTTCAGCTGCTGTCCCGCATTGGCCACAAGCACGTGTCCCTCGGCATTACTGC
TGATCAGTACGACATTGTTCACGAGCACCTGTTCGCCGCAATCGTTGAGGTTTTGGGAGCGGAAACTGTCACCGCACCTG
TCGCTGAAGCCTGGGATGCTGTCTACTGGATCATGGCAAATGTGCTGATCGGTTTTGAGAACAACCTTTATGCTTCCAAC
GATCTGGAGCCTGGCGACGTCTTCCGCGAAGTCACCGTGACCGCGAAGAAGCAGCTCAGCGCAACCGTCTGGGAATACAC
CCTGGCAGGTGAGCTGGTTGCCCCAGAGCCAGGTCAGTACACCTCCATCGGAGTAGTGCTTGACGACGGCGCCCGCCAGC
TGCGCCAGTACAGCTTGCTCGGCGGCTCCGACACCGAGTACCGCATTGCGGTTGAGGATAACGGCGAGGTTTCTGGATTC
CTGCGTGATCGCGTATCCGTTGGTGACAAGATTGAAGCCACCATCGCGGCCGGCGACCTGGTTCTTAACAAGGACACCAA
TCCAGTTGTGCTGATTTCCCAGGGCATCGGCTCCACCCCAATGGTGGGCATGCTCGCAGGTATGAACCCTGAACGTGACG
TTGTGGTTTTGCATGCTGACCAGGCCGAGTCCACCTACGCGCAGGTGGAGGAAGTGCAGGGGCTCGTCGAAAAGCTCCCT
AAGGCTGCGTTTGAAATCTTCTACCGCGACAACGACCAGTGGCTCGAGGTCGCTGGCCGCATTCCATCAGGTGCGTCCGT
GTACCTGTGCGGTGGCGTGGAATTCTTGAAGAACGTGCGTGAGCAGATCGAGGCGCTCGATGAGCAGCCTCGCGACGTAA
ACTTCGAGCTCTTCGCACCAAACGACTGGCTGATTTCCTAA

Upstream 100 bases:

>100_bases
TGCCATCATATTAAGGCCAAATTGCTTGGATCCTGGGATTTATTTAATTAGATTAAATCCGTAGAAATTAGCCCATGAAG
CATGGAAAGGCGAAAACCCC

Downstream 100 bases:

>100_bases
GCCCACACCCCAGAACTTCCGCGGCGATGGCTGCCCACCAAATGGGTGTCGACGATTCCTATGGCTTCCATAAGGGCAAA
CATCGTCGTGGGACCAACGA

Product: flavohemoprotein

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MIVSTQPITDRSALSAEHAEVIKATLPLVGGKINEITPVFYNKMFAAHPELIANTFNRGNQKQGDQQKALAASIATFATM
LVTPDAPDPVQLLSRIGHKHVSLGITADQYDIVHEHLFAAIVEVLGAETVTAPVAEAWDAVYWIMANVLIGFENNLYASN
DLEPGDVFREVTVTAKKQLSATVWEYTLAGELVAPEPGQYTSIGVVLDDGARQLRQYSLLGGSDTEYRIAVEDNGEVSGF
LRDRVSVGDKIEATIAAGDLVLNKDTNPVVLISQGIGSTPMVGMLAGMNPERDVVVLHADQAESTYAQVEEVQGLVEKLP
KAAFEIFYRDNDQWLEVAGRIPSGASVYLCGGVEFLKNVREQIEALDEQPRDVNFELFAPNDWLIS

Sequences:

>Translated_386_residues
MIVSTQPITDRSALSAEHAEVIKATLPLVGGKINEITPVFYNKMFAAHPELIANTFNRGNQKQGDQQKALAASIATFATM
LVTPDAPDPVQLLSRIGHKHVSLGITADQYDIVHEHLFAAIVEVLGAETVTAPVAEAWDAVYWIMANVLIGFENNLYASN
DLEPGDVFREVTVTAKKQLSATVWEYTLAGELVAPEPGQYTSIGVVLDDGARQLRQYSLLGGSDTEYRIAVEDNGEVSGF
LRDRVSVGDKIEATIAAGDLVLNKDTNPVVLISQGIGSTPMVGMLAGMNPERDVVVLHADQAESTYAQVEEVQGLVEKLP
KAAFEIFYRDNDQWLEVAGRIPSGASVYLCGGVEFLKNVREQIEALDEQPRDVNFELFAPNDWLIS
>Mature_386_residues
MIVSTQPITDRSALSAEHAEVIKATLPLVGGKINEITPVFYNKMFAAHPELIANTFNRGNQKQGDQQKALAASIATFATM
LVTPDAPDPVQLLSRIGHKHVSLGITADQYDIVHEHLFAAIVEVLGAETVTAPVAEAWDAVYWIMANVLIGFENNLYASN
DLEPGDVFREVTVTAKKQLSATVWEYTLAGELVAPEPGQYTSIGVVLDDGARQLRQYSLLGGSDTEYRIAVEDNGEVSGF
LRDRVSVGDKIEATIAAGDLVLNKDTNPVVLISQGIGSTPMVGMLAGMNPERDVVVLHADQAESTYAQVEEVQGLVEKLP
KAAFEIFYRDNDQWLEVAGRIPSGASVYLCGGVEFLKNVREQIEALDEQPRDVNFELFAPNDWLIS

Specific function: Possesses Dihydropteridine Reductase Activity. Also Has Nitric Oxide Dioxygenase Activity. Seems To Reduces The Complexed Fe(3+) Iron Of Siderophores To Fe(2+), Thus Releasing It From The Chelator. [C]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=401, Percent_Identity=32.1695760598504, Blast_Score=172, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6321673, Length=399, Percent_Identity=30.5764411027569, Blast_Score=148, Evalue=2e-36,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 42011; Mature: 42011

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVSTQPITDRSALSAEHAEVIKATLPLVGGKINEITPVFYNKMFAAHPELIANTFNRGN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCC
QKQGDQQKALAASIATFATMLVTPDAPDPVQLLSRIGHKHVSLGITADQYDIVHEHLFAA
CCCCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHH
IVEVLGAETVTAPVAEAWDAVYWIMANVLIGFENNLYASNDLEPGDVFREVTVTAKKQLS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHH
ATVWEYTLAGELVAPEPGQYTSIGVVLDDGARQLRQYSLLGGSDTEYRIAVEDNGEVSGF
HHHHEEEECCCEECCCCCCEEEEEEEECCHHHHHHHHHHCCCCCCEEEEEEECCCCCHHH
LRDRVSVGDKIEATIAAGDLVLNKDTNPVVLISQGIGSTPMVGMLAGMNPERDVVVLHAD
HHHHHCCCCCEEEEEEECEEEEECCCCCEEEEECCCCCCCHHHHHHCCCCCCCEEEEECC
QAESTYAQVEEVQGLVEKLPKAAFEIFYRDNDQWLEVAGRIPSGASVYLCGGVEFLKNVR
CCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHCCCCCCCCEEEEECCHHHHHHHH
EQIEALDEQPRDVNFELFAPNDWLIS
HHHHHHHCCCCCCCEEEECCCCCCCC
>Mature Secondary Structure
MIVSTQPITDRSALSAEHAEVIKATLPLVGGKINEITPVFYNKMFAAHPELIANTFNRGN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCC
QKQGDQQKALAASIATFATMLVTPDAPDPVQLLSRIGHKHVSLGITADQYDIVHEHLFAA
CCCCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHH
IVEVLGAETVTAPVAEAWDAVYWIMANVLIGFENNLYASNDLEPGDVFREVTVTAKKQLS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHH
ATVWEYTLAGELVAPEPGQYTSIGVVLDDGARQLRQYSLLGGSDTEYRIAVEDNGEVSGF
HHHHEEEECCCEECCCCCCEEEEEEEECCHHHHHHHHHHCCCCCCEEEEEEECCCCCHHH
LRDRVSVGDKIEATIAAGDLVLNKDTNPVVLISQGIGSTPMVGMLAGMNPERDVVVLHAD
HHHHHCCCCCEEEEEEECEEEEECCCCCEEEEECCCCCCCHHHHHHCCCCCCCEEEEECC
QAESTYAQVEEVQGLVEKLPKAAFEIFYRDNDQWLEVAGRIPSGASVYLCGGVEFLKNVR
CCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHCCCCCCCCEEEEECCHHHHHHHH
EQIEALDEQPRDVNFELFAPNDWLIS
HHHHHHHCCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]