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The map label for this gene is ackA [H]

Identifier: 62391588

GI number: 62391588

Start: 2908620

End: 2909813

Strand: Reverse

Name: ackA [H]

Synonym: cg3047

Alternate gene names: 62391588

Gene position: 2909813-2908620 (Counterclockwise)

Preceding gene: 62391589

Following gene: 62391584

Centisome position: 88.64

GC content: 51.84

Gene sequence:

>1194_bases
ATGGCATTGGCACTTGTTTTGAACTCCGGTTCATCTTCCATCAAATTCCAGCTGGTCAACCCCGAAAACTCTGCCATCGA
CGAGCCATATGTTTCTGGTCTTGTGGAGCAGATTGGTGAGCCAAACGGCCGCATCGTACTCAAAATAGAGGGTGAAAAAT
ATACCCTAGAGACACCCATCGCAGATCACTCCGAAGGCCTAAACCTGGCGTTCGATCTCATGGACCAGCACAACTGTGGT
CCTTCCCAACTGGAAATCACCGCAGTTGGACACCGCGTGGTCCACGGCGGAATCTTGTTCTCCGCACCGGAACTTATCAC
TGATGAAATCGTGGAAATGATCCGCGATCTCATTCCACTCGCACCACTGCACAACCCTGCAAACGTTGACGGCATTGATG
TTGCTCGAAAAATTCTCCCCGATGTCCCACACGTAGCTGTCTTTGACACCGGTTTCTTCCACTCACTTCCACCAGCAGCT
GCGCTGTATGCCATCAACAAGGATGTCGCAGCTGAACACGGAATCAGGCGCTATGGTTTCCACGGCACCTCCCATGAATT
TGTGTCCAAGCGCGTGGTGGAAATTCTGGAAAAGCCCACCGAAGACATCAACACCATCACCTTCCACCTGGGCAACGGCG
CATCCATGGCTGCTGTTCAAGGTGGCCGTGCGGTAGATACTTCCATGGGTATGACACCTCTCGCGGGCCTTGTCATGGGT
ACCCGAAGCGGTGACATTGATCCAGGTATCGTCTTCCACCTTTCCCGCACCGCTGGCATGAGCATCGATGAGATCGATAA
TCTGCTGAACAAAAAGTCGGGTGTAAAGGGACTTTCCGGTGTTAATGATTTCCGTGAACTGCGGGAAATGATCGACAACA
ATGATCAAGATGCCTGGTCCGCGTACAACATTTACATACACCAACTCCGCCGCTACCTCGGTTCCTACATGGTGGCACTG
GGACGGGTAGACACCATCGTGTTCACCGCCGGTGTCGGTGAAAATGCCCAGTTTGTCCGTGAGGATGCCTTGGCAGGTTT
GGAAATGTACGGAATTGAGATCGATCCAGAGCGTAACGCATTGCCAAACGATGGTCCTCGATTGATTTCCACCGATGCCT
CCAAGGTGAAGGTGTTTGTTATTCCAACTAATGAAGAGTTAGCTATCGCTAGGTACGCGGTGAAGTTCGCTTAG

Upstream 100 bases:

>100_bases
GCCTAAACAAACCAGTCAACGACCTTTCCCGTGGCGCAACAGTCCCTGACATCGTCAACACAGTAGCCATCACAGCAATT
CAGGCAGGAGGACGCAGCTA

Downstream 100 bases:

>100_bases
CTCTCCTGGTTAGGATCCACCACAAATCGCTCTGATCAGCGGTTTTGTGGTGGATTTTTGCGTTTTTAAGGGGTGAAACT
GCACGGATCCACCACAGATC

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MALALVLNSGSSSIKFQLVNPENSAIDEPYVSGLVEQIGEPNGRIVLKIEGEKYTLETPIADHSEGLNLAFDLMDQHNCG
PSQLEITAVGHRVVHGGILFSAPELITDEIVEMIRDLIPLAPLHNPANVDGIDVARKILPDVPHVAVFDTGFFHSLPPAA
ALYAINKDVAAEHGIRRYGFHGTSHEFVSKRVVEILEKPTEDINTITFHLGNGASMAAVQGGRAVDTSMGMTPLAGLVMG
TRSGDIDPGIVFHLSRTAGMSIDEIDNLLNKKSGVKGLSGVNDFRELREMIDNNDQDAWSAYNIYIHQLRRYLGSYMVAL
GRVDTIVFTAGVGENAQFVREDALAGLEMYGIEIDPERNALPNDGPRLISTDASKVKVFVIPTNEELAIARYAVKFA

Sequences:

>Translated_397_residues
MALALVLNSGSSSIKFQLVNPENSAIDEPYVSGLVEQIGEPNGRIVLKIEGEKYTLETPIADHSEGLNLAFDLMDQHNCG
PSQLEITAVGHRVVHGGILFSAPELITDEIVEMIRDLIPLAPLHNPANVDGIDVARKILPDVPHVAVFDTGFFHSLPPAA
ALYAINKDVAAEHGIRRYGFHGTSHEFVSKRVVEILEKPTEDINTITFHLGNGASMAAVQGGRAVDTSMGMTPLAGLVMG
TRSGDIDPGIVFHLSRTAGMSIDEIDNLLNKKSGVKGLSGVNDFRELREMIDNNDQDAWSAYNIYIHQLRRYLGSYMVAL
GRVDTIVFTAGVGENAQFVREDALAGLEMYGIEIDPERNALPNDGPRLISTDASKVKVFVIPTNEELAIARYAVKFA
>Mature_396_residues
ALALVLNSGSSSIKFQLVNPENSAIDEPYVSGLVEQIGEPNGRIVLKIEGEKYTLETPIADHSEGLNLAFDLMDQHNCGP
SQLEITAVGHRVVHGGILFSAPELITDEIVEMIRDLIPLAPLHNPANVDGIDVARKILPDVPHVAVFDTGFFHSLPPAAA
LYAINKDVAAEHGIRRYGFHGTSHEFVSKRVVEILEKPTEDINTITFHLGNGASMAAVQGGRAVDTSMGMTPLAGLVMGT
RSGDIDPGIVFHLSRTAGMSIDEIDNLLNKKSGVKGLSGVNDFRELREMIDNNDQDAWSAYNIYIHQLRRYLGSYMVALG
RVDTIVFTAGVGENAQFVREDALAGLEMYGIEIDPERNALPNDGPRLISTDASKVKVFVIPTNEELAIARYAVKFA

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788633, Length=402, Percent_Identity=46.0199004975124, Blast_Score=330, Evalue=8e-92,
Organism=Escherichia coli, GI145693184, Length=399, Percent_Identity=40.6015037593985, Blast_Score=291, Evalue=5e-80,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 43093; Mature: 42961

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALALVLNSGSSSIKFQLVNPENSAIDEPYVSGLVEQIGEPNGRIVLKIEGEKYTLETPI
CEEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCEEEEECCC
ADHSEGLNLAFDLMDQHNCGPSQLEITAVGHRVVHGGILFSAPELITDEIVEMIRDLIPL
CCCCCCCCEEEEEHHCCCCCCCEEEEEEECCEEEECCEEECCHHHHHHHHHHHHHHHHCC
APLHNPANVDGIDVARKILPDVPHVAVFDTGFFHSLPPAAALYAINKDVAAEHGIRRYGF
CCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHEECCCHHHHHCCCHHHCC
HGTSHEFVSKRVVEILEKPTEDINTITFHLGNGASMAAVQGGRAVDTSMGMTPLAGLVMG
CCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEECCCCEECCCCCCHHHHHHEEE
TRSGDIDPGIVFHLSRTAGMSIDEIDNLLNKKSGVKGLSGVNDFRELREMIDNNDQDAWS
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHH
AYNIYIHQLRRYLGSYMVALGRVDTIVFTAGVGENAQFVREDALAGLEMYGIEIDPERNA
HHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCCEEEEEEEECCCCCC
LPNDGPRLISTDASKVKVFVIPTNEELAIARYAVKFA
CCCCCCEEEECCCCEEEEEEEECCCCEEEEEEEEECC
>Mature Secondary Structure 
ALALVLNSGSSSIKFQLVNPENSAIDEPYVSGLVEQIGEPNGRIVLKIEGEKYTLETPI
EEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCEEEEECCC
ADHSEGLNLAFDLMDQHNCGPSQLEITAVGHRVVHGGILFSAPELITDEIVEMIRDLIPL
CCCCCCCCEEEEEHHCCCCCCCEEEEEEECCEEEECCEEECCHHHHHHHHHHHHHHHHCC
APLHNPANVDGIDVARKILPDVPHVAVFDTGFFHSLPPAAALYAINKDVAAEHGIRRYGF
CCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHEECCCHHHHHCCCHHHCC
HGTSHEFVSKRVVEILEKPTEDINTITFHLGNGASMAAVQGGRAVDTSMGMTPLAGLVMG
CCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEECCCCEECCCCCCHHHHHHEEE
TRSGDIDPGIVFHLSRTAGMSIDEIDNLLNKKSGVKGLSGVNDFRELREMIDNNDQDAWS
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHH
AYNIYIHQLRRYLGSYMVALGRVDTIVFTAGVGENAQFVREDALAGLEMYGIEIDPERNA
HHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCCEEEEEEEECCCCCC
LPNDGPRLISTDASKVKVFVIPTNEELAIARYAVKFA
CCCCCCEEEECCCCEEEEEEEECCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA