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The map label for this gene is mutT3 [H]

Identifier: 62391584

GI number: 62391584

Start: 2902561

End: 2903055

Strand: Reverse

Name: mutT3 [H]

Synonym: cg3043

Alternate gene names: 62391584

Gene position: 2903055-2902561 (Counterclockwise)

Preceding gene: 62391588

Following gene: 62391583

Centisome position: 88.43

GC content: 54.55

Gene sequence:

>495_bases
ATGAAAGGCGACGGCGATGGATGGGCAGCAGCACCCAATGGCGGGGCAGTATGGGGCAAAAACGGAGCAGCAGGATTGTT
GTTGGTAGCAGATAAACAAATGCTCATGCAGCACCGAGCCGCATGGACCAACAACGGCGACACCTGGGCACTCCCTGGAG
GCGCACGAGACTCACATGAAACCGCAGCGGAATCAGCCCTGCGTGAAGCATTTGAAGAAACTGGAATCCTGCCCGACGAC
GTGGAAGTTTTAGATTCAATAGTCACCGCAGGCCCTTTTCCCGCCGATCCAGAACGCCCAGAACTTGCCGGCAACTGGAC
CTACACCACGGTCATCGCACGAACTAAAACCGGCGAAACCCTAGATACCACCGCTAATGAAGAATCCCTCGAACTACGGT
GGGTAGATATCGCAGCGGTTGACTCTTTGGCTTTGATGCCAGCATTCGCCAAAGCGTGGCCCTCTTTAAGAAAGCTACTG
AACACAACAGAGTAG

Upstream 100 bases:

>100_bases
CCATCCCGGATCATTGTTTCAGAATAGCGTGACTCATGACATGTTGAAAGTATTGGCTACCTTGATGAATACCCCCAGCG
TTTAGCCTAATGTGGACACC

Downstream 100 bases:

>100_bases
GTTTATGCGACACTGGTGCGCATGATCAACGTTGAAGGCCTCACCAAACAATATGGTCAGGTCCGCGCAGTCGATGATCT
GAGCTTCGAAGTAAAACCCG

Product: NTP pyrophosphohydrolase/oxidative damage repair enzyme

Products: NA

Alternate protein names: 7,8-dihydro-8-oxoguanine-triphosphatase; 8-oxo-dGTPase; dGTP pyrophosphohydrolase [H]

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MKGDGDGWAAAPNGGAVWGKNGAAGLLLVADKQMLMQHRAAWTNNGDTWALPGGARDSHETAAESALREAFEETGILPDD
VEVLDSIVTAGPFPADPERPELAGNWTYTTVIARTKTGETLDTTANEESLELRWVDIAAVDSLALMPAFAKAWPSLRKLL
NTTE

Sequences:

>Translated_164_residues
MKGDGDGWAAAPNGGAVWGKNGAAGLLLVADKQMLMQHRAAWTNNGDTWALPGGARDSHETAAESALREAFEETGILPDD
VEVLDSIVTAGPFPADPERPELAGNWTYTTVIARTKTGETLDTTANEESLELRWVDIAAVDSLALMPAFAKAWPSLRKLL
NTTE
>Mature_164_residues
MKGDGDGWAAAPNGGAVWGKNGAAGLLLVADKQMLMQHRAAWTNNGDTWALPGGARDSHETAAESALREAFEETGILPDD
VEVLDSIVTAGPFPADPERPELAGNWTYTTVIARTKTGETLDTTANEESLELRWVDIAAVDSLALMPAFAKAWPSLRKLL
NTTE

Specific function: May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool. 8-oxo- dGTP is inserted opposite dA and dC residues of template DNA with almost equa

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 17489; Mature: 17489

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGDGDGWAAAPNGGAVWGKNGAAGLLLVADKQMLMQHRAAWTNNGDTWALPGGARDSHE
CCCCCCCEEECCCCCEEECCCCCCEEEEEECHHHHHHHHHHCCCCCCEEECCCCCCCHHH
TAAESALREAFEETGILPDDVEVLDSIVTAGPFPADPERPELAGNWTYTTVIARTKTGET
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCCC
LDTTANEESLELRWVDIAAVDSLALMPAFAKAWPSLRKLLNTTE
CCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKGDGDGWAAAPNGGAVWGKNGAAGLLLVADKQMLMQHRAAWTNNGDTWALPGGARDSHE
CCCCCCCEEECCCCCEEECCCCCCEEEEEECHHHHHHHHHHCCCCCCEEECCCCCCCHHH
TAAESALREAFEETGILPDDVEVLDSIVTAGPFPADPERPELAGNWTYTTVIARTKTGET
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCCC
LDTTANEESLELRWVDIAAVDSLALMPAFAKAWPSLRKLLNTTE
CCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]