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The map label for this gene is ksdD [H]

Identifier: 62391472

GI number: 62391472

Start: 2774864

End: 2776555

Strand: Reverse

Name: ksdD [H]

Synonym: cg2916

Alternate gene names: 62391472

Gene position: 2776555-2774864 (Counterclockwise)

Preceding gene: 62391473

Following gene: 62391466

Centisome position: 84.58

GC content: 55.61

Gene sequence:

>1692_bases
ATGAAACACCAATATGATGTCATCGTTGTCGGTTCCGGCGCTGGCGGATTATCAGCTGCAGTCAGTGCAGCTTACGGCGG
TAAGAAAGTCGCTGTAATTGAAAAGGCCTCAGTACTCGGTGGAGCCACCACCTGGTCCGGCGGTTGGGCTTGGACTCCTG
GAACCAGCCTTGCGCGCAAAGACGGAGTAGTGGAATCCAAAGAAGAATTCCAAACCTACCTGCAAGCGGTAGTGGGGGAG
TACTACCAAGAAGACAACATCTCCGCCTTCTTGGACGCAGCCCCTGAAATGGTCGATTTCTTTGAAAAAAACACCGACCT
GCAGTGGACCCCCGGCGCGAAAATCAACGACATCTACGGCAACCTCCCCGGTGCTGGCACTGGACACCGCTCCGTTGGGC
CAAAACCATTCAACGGACGCAAAGTACCCAAGAGTGTTCTTCCAAAACTGCGCCACCAGCTGTATGAAACCTCCTTCCTG
GGAATGGGCATCATGGCTGGGCCTGACCTGACGAAATTCCTCTCTGCTTCACAGTTCGATCCACGTGGTTGGGTACATGC
CGCCAGGCGCGTCATCGTGCACATGTGGGACATGGTCGTGCACAAACGCAATATGCAGATGGTCAACGGTGCAGCACTCA
CCGCTCGACTGGCTACCTCTGCAGACAAGCTGGGCGTTGATCTCCTGGTCAATCACTCCGCAGTGTCGTTGAATTACAAA
AACGACCGCGTTACCGGCGTGAAAGTACAAACCCCACAGGGCTTGGTAGATTTCGAAGCCACTGCCGGCGTCGTGCTCGC
CACTGGTGGATTCCCCAACAACGTTGACCTGCGCAAGGAACTCTTCCCACGCACCCCATCAGGTCAAGAACACTGGACCC
TCGCGCCAGCAGAAACCACCGGCGACGGACTATCCATGGCTCGGGAAATCGGTGCAGGTTTTGTCAACGACCTGAAATCC
CCAGCAGCATGGTGCCCTGTTTCATTGGTCCCATACTTCAACGGAAAAGTCGGCACCTTCCCCCACATCATGGACCGCGC
AAAACCAGGCTCCATCGGTGTTGTCTCCACAGGTAAGCGATTCGTCAATGAAGCCAACGGCTACTACGACTACGTTGACG
CCATGCTGAAAGCAGCCCCCGAAGGCGAACCAGTTGCATCCTGGCAGATCGCCGACTCCACCTTCGTGCGCAAATACCCA
CTGGGAATGGCCAAGCCACTACCCGTACCACTCACCCCATACCTGCGTTCTGGATACTTGGTAAAGGGCAAAACCATCGA
GGAACTAGCCCAAAAATGTGGCATTGATCCTGCAGGTTTGCGCGCCACCGTCACGGAATTCAATGAAAACGCGCGCCGGG
GCGAAGACCCAGAATTCGGTCGCGGATCCACTTCATTCAACAAGTACGGTGGCGACCCCAAGATCGGCCCCAACCCATCA
CTCGCACCAATCGAAAAGGGCCCGTTCTACGCTGTGAAAGTTGTTCCGGGTTCGTTTGGCACCTTCGATGGCATCAAAGC
CGATGGAAAATCACGAGTTCTCCGCGATGACGACACGATCATCGATGGCCTCTACACCGCAGGCAACGATCGTGCCTCCA
TCATGGGTGGTTTCTACCCAGCAGGTGGCATCAACCTTGGCCCAGCGCTGGCATTCGGATACATCGCGGGCAAAGAACTG
GCTAACTCCTAA

Upstream 100 bases:

>100_bases
CAACGATGGGGAAGTAGCCTCTCGTGGCGACGCCGGATGGATCAACCACCTCTACAACACCACCCAAGCTCTGTTAGAAA
AAATTGAGGAAGCAGTCTAA

Downstream 100 bases:

>100_bases
ATGTCGATTTCTTAACAGCGATTTCGGTCGGAAAACCGGGGAAAACCGAGCGAAATCGCCGCTGAGAAATTGAGCTTGAG
GTATTGGAACCGTGAAATCG

Product: hypothetical protein

Products: NA

Alternate protein names: 3-keto-Delta(4)-steroid Delta(1)-dehydrogenase; KSDD; 3-oxo-Delta(4)-steroid 1-dehydrogenase; KSTD [H]

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MKHQYDVIVVGSGAGGLSAAVSAAYGGKKVAVIEKASVLGGATTWSGGWAWTPGTSLARKDGVVESKEEFQTYLQAVVGE
YYQEDNISAFLDAAPEMVDFFEKNTDLQWTPGAKINDIYGNLPGAGTGHRSVGPKPFNGRKVPKSVLPKLRHQLYETSFL
GMGIMAGPDLTKFLSASQFDPRGWVHAARRVIVHMWDMVVHKRNMQMVNGAALTARLATSADKLGVDLLVNHSAVSLNYK
NDRVTGVKVQTPQGLVDFEATAGVVLATGGFPNNVDLRKELFPRTPSGQEHWTLAPAETTGDGLSMAREIGAGFVNDLKS
PAAWCPVSLVPYFNGKVGTFPHIMDRAKPGSIGVVSTGKRFVNEANGYYDYVDAMLKAAPEGEPVASWQIADSTFVRKYP
LGMAKPLPVPLTPYLRSGYLVKGKTIEELAQKCGIDPAGLRATVTEFNENARRGEDPEFGRGSTSFNKYGGDPKIGPNPS
LAPIEKGPFYAVKVVPGSFGTFDGIKADGKSRVLRDDDTIIDGLYTAGNDRASIMGGFYPAGGINLGPALAFGYIAGKEL
ANS

Sequences:

>Translated_563_residues
MKHQYDVIVVGSGAGGLSAAVSAAYGGKKVAVIEKASVLGGATTWSGGWAWTPGTSLARKDGVVESKEEFQTYLQAVVGE
YYQEDNISAFLDAAPEMVDFFEKNTDLQWTPGAKINDIYGNLPGAGTGHRSVGPKPFNGRKVPKSVLPKLRHQLYETSFL
GMGIMAGPDLTKFLSASQFDPRGWVHAARRVIVHMWDMVVHKRNMQMVNGAALTARLATSADKLGVDLLVNHSAVSLNYK
NDRVTGVKVQTPQGLVDFEATAGVVLATGGFPNNVDLRKELFPRTPSGQEHWTLAPAETTGDGLSMAREIGAGFVNDLKS
PAAWCPVSLVPYFNGKVGTFPHIMDRAKPGSIGVVSTGKRFVNEANGYYDYVDAMLKAAPEGEPVASWQIADSTFVRKYP
LGMAKPLPVPLTPYLRSGYLVKGKTIEELAQKCGIDPAGLRATVTEFNENARRGEDPEFGRGSTSFNKYGGDPKIGPNPS
LAPIEKGPFYAVKVVPGSFGTFDGIKADGKSRVLRDDDTIIDGLYTAGNDRASIMGGFYPAGGINLGPALAFGYIAGKEL
ANS
>Mature_563_residues
MKHQYDVIVVGSGAGGLSAAVSAAYGGKKVAVIEKASVLGGATTWSGGWAWTPGTSLARKDGVVESKEEFQTYLQAVVGE
YYQEDNISAFLDAAPEMVDFFEKNTDLQWTPGAKINDIYGNLPGAGTGHRSVGPKPFNGRKVPKSVLPKLRHQLYETSFL
GMGIMAGPDLTKFLSASQFDPRGWVHAARRVIVHMWDMVVHKRNMQMVNGAALTARLATSADKLGVDLLVNHSAVSLNYK
NDRVTGVKVQTPQGLVDFEATAGVVLATGGFPNNVDLRKELFPRTPSGQEHWTLAPAETTGDGLSMAREIGAGFVNDLKS
PAAWCPVSLVPYFNGKVGTFPHIMDRAKPGSIGVVSTGKRFVNEANGYYDYVDAMLKAAPEGEPVASWQIADSTFVRKYP
LGMAKPLPVPLTPYLRSGYLVKGKTIEELAQKCGIDPAGLRATVTEFNENARRGEDPEFGRGSTSFNKYGGDPKIGPNPS
LAPIEKGPFYAVKVVPGSFGTFDGIKADGKSRVLRDDDTIIDGLYTAGNDRASIMGGFYPAGGINLGPALAFGYIAGKEL
ANS

Specific function: Catalyzes the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3- ketosteroids. Is also involved in the formation of 1,4- androstadiene-3,17-dione (ADD) from 4-androstene-3,17-dione (AD) to [H]

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. 3-oxosteroid dehydrogenase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.3.99.4 [H]

Molecular weight: Translated: 60176; Mature: 60176

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHQYDVIVVGSGAGGLSAAVSAAYGGKKVAVIEKASVLGGATTWSGGWAWTPGTSLARK
CCCEEEEEEEECCCCCHHHHHHHHCCCCEEEEEEEHHHCCCCCCCCCCEEECCCCCHHHH
DGVVESKEEFQTYLQAVVGEYYQEDNISAFLDAAPEMVDFFEKNTDLQWTPGAKINDIYG
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHCCCCCEECCCCCEEHHCC
NLPGAGTGHRSVGPKPFNGRKVPKSVLPKLRHQLYETSFLGMGIMAGPDLTKFLSASQFD
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHCCCCC
PRGWVHAARRVIVHMWDMVVHKRNMQMVNGAALTARLATSADKLGVDLLVNHSAVSLNYK
CHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHCHHHCCEEEEEECEEEEEEEC
NDRVTGVKVQTPQGLVDFEATAGVVLATGGFPNNVDLRKELFPRTPSGQEHWTLAPAETT
CCCEEEEEEECCCCCEEECCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCEEECCCCCC
GDGLSMAREIGAGFVNDLKSPAAWCPVSLVPYFNGKVGTFPHIMDRAKPGSIGVVSTGKR
CCHHHHHHHHCCHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHCCCCCCEEEEECCHH
FVNEANGYYDYVDAMLKAAPEGEPVASWQIADSTFVRKYPLGMAKPLPVPLTPYLRSGYL
HHHHCCCHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHCCCCCCCCCCCCCCHHHHCCEE
VKGKTIEELAQKCGIDPAGLRATVTEFNENARRGEDPEFGRGSTSFNKYGGDPKIGPNPS
EECCHHHHHHHHHCCCCCCCEEEHHHHCCHHCCCCCCCCCCCCCCCHHCCCCCCCCCCCC
LAPIEKGPFYAVKVVPGSFGTFDGIKADGKSRVLRDDDTIIDGLYTAGNDRASIMGGFYP
CCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEECCCCHHHHHEEECCCCCHHEECCCCC
AGGINLGPALAFGYIAGKELANS
CCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKHQYDVIVVGSGAGGLSAAVSAAYGGKKVAVIEKASVLGGATTWSGGWAWTPGTSLARK
CCCEEEEEEEECCCCCHHHHHHHHCCCCEEEEEEEHHHCCCCCCCCCCEEECCCCCHHHH
DGVVESKEEFQTYLQAVVGEYYQEDNISAFLDAAPEMVDFFEKNTDLQWTPGAKINDIYG
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHCCCCCEECCCCCEEHHCC
NLPGAGTGHRSVGPKPFNGRKVPKSVLPKLRHQLYETSFLGMGIMAGPDLTKFLSASQFD
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHCCCCC
PRGWVHAARRVIVHMWDMVVHKRNMQMVNGAALTARLATSADKLGVDLLVNHSAVSLNYK
CHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHCHHHCCEEEEEECEEEEEEEC
NDRVTGVKVQTPQGLVDFEATAGVVLATGGFPNNVDLRKELFPRTPSGQEHWTLAPAETT
CCCEEEEEEECCCCCEEECCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCEEECCCCCC
GDGLSMAREIGAGFVNDLKSPAAWCPVSLVPYFNGKVGTFPHIMDRAKPGSIGVVSTGKR
CCHHHHHHHHCCHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHCCCCCCEEEEECCHH
FVNEANGYYDYVDAMLKAAPEGEPVASWQIADSTFVRKYPLGMAKPLPVPLTPYLRSGYL
HHHHCCCHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHCCCCCCCCCCCCCCHHHHCCEE
VKGKTIEELAQKCGIDPAGLRATVTEFNENARRGEDPEFGRGSTSFNKYGGDPKIGPNPS
EECCHHHHHHHHHCCCCCCCEEEHHHHCCHHCCCCCCCCCCCCCCCHHCCCCCCCCCCCC
LAPIEKGPFYAVKVVPGSFGTFDGIKADGKSRVLRDDDTIIDGLYTAGNDRASIMGGFYP
CCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEECCCCHHHHHEEECCCCCHHEECCCCC
AGGINLGPALAFGYIAGKELANS
CCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA