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The map label for this gene is era [H]

Identifier: 62391126

GI number: 62391126

Start: 2389641

End: 2390639

Strand: Reverse

Name: era [H]

Synonym: cg2510

Alternate gene names: 62391126

Gene position: 2390639-2389641 (Counterclockwise)

Preceding gene: 62391127

Following gene: 62391125

Centisome position: 72.83

GC content: 56.96

Gene sequence:

>999_bases
ATGCTGGGACGTCCAAGGAAACCGGCCCTTTTTTGCCAAGAAGTGGCTGGTTCGATCATCCCAAACTTTCAAAGAGGATT
TATGAGCTTTACCGATACCCCTGATGGCTTCCGCTCCGGCTTCGTCAGCTTCGTGGGACGTCCCAACACCGGCAAGTCCA
CCCTGACCAACGCGCTGGTCGGCGAGAAAATCGCCATCACCGCAAACCAGCCAGAAACCACCCGCCACCCAATCCGTGGC
TTGGTCCACCGCGACAACGCACAGATCATCGTCGTGGACACCCCAGGCCTGCACCGCCCACGCACCTTGCTGGGTGAGCG
CCTCAACGAAGCAGTTAAAGACACCTACGCTGACGTCGACCTGATCGGTTTCACCGTTCCAGCAAACGAGAAGATTGGTC
CTGGCGACCGCTGGATCCTTGAAGCAGTCCGCAAGGTATCGCCTAAAACTCCTATCCTCGGCATCATCACCAAAGCAGAC
AGCGTCTCACGTGACTTGGTTGCGGCCCAACTGATGGCTGTCCATGAGCTGCTCGGCGGAAACAGCGAGGTAGTCCCAGT
GTCTTCCACCTCGGGGGAAAACGTCGAAACGCTTATTAAGGTCATGACCGACCTGCTGCCTGAAGGCCCCAAGTTCTACC
CGGATGATCACATCACCGATGAGGACACCAACACCCGCATCGCGGAAGCCATCCGCGAAGCAGCACTGTCTGGCTTGAAG
AACGAACTGCCGCACTCCGTCGCAGTTGAGGTTGATGAAATCCTGCCAGACCCAGAACGCAACGGTGTCCTGGCTGTGCA
CGCCATCATCTACGTCGAGCGTGTTGGTCAGAAAGACATCATCGTCGGACACAAGGGACAGCGCCTGGGGCGCATCATCC
ACACCTCACGCCAAGACATCATCAAGATCCTCGGCCAAAACGTATTCCTTGACCTGCGCATCAAGGTGCTGAAGAACTGG
CAATCCGATCCAAAGGCTTTGAACCGCCTGGGCTTCTAG

Upstream 100 bases:

>100_bases
AAGAACCGCCGGGGTCGTTTGCGCATGCATTCAGCAGTCGTAGAAGTTGGCGAGCCCAGCGAGGACAACGAAGGTTAGTT
TTTTACAGCAGTAGGGGACT

Downstream 100 bases:

>100_bases
CTTTAAGGGGGTGAGTTCATGCGTAGGGACAGTTTTCGGGACCGCGCGCTAGTAGTCAAAACTTATGATTTTGGCGAAGC
CGACCGCATTATTGTGCTGC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MLGRPRKPALFCQEVAGSIIPNFQRGFMSFTDTPDGFRSGFVSFVGRPNTGKSTLTNALVGEKIAITANQPETTRHPIRG
LVHRDNAQIIVVDTPGLHRPRTLLGERLNEAVKDTYADVDLIGFTVPANEKIGPGDRWILEAVRKVSPKTPILGIITKAD
SVSRDLVAAQLMAVHELLGGNSEVVPVSSTSGENVETLIKVMTDLLPEGPKFYPDDHITDEDTNTRIAEAIREAALSGLK
NELPHSVAVEVDEILPDPERNGVLAVHAIIYVERVGQKDIIVGHKGQRLGRIIHTSRQDIIKILGQNVFLDLRIKVLKNW
QSDPKALNRLGF

Sequences:

>Translated_332_residues
MLGRPRKPALFCQEVAGSIIPNFQRGFMSFTDTPDGFRSGFVSFVGRPNTGKSTLTNALVGEKIAITANQPETTRHPIRG
LVHRDNAQIIVVDTPGLHRPRTLLGERLNEAVKDTYADVDLIGFTVPANEKIGPGDRWILEAVRKVSPKTPILGIITKAD
SVSRDLVAAQLMAVHELLGGNSEVVPVSSTSGENVETLIKVMTDLLPEGPKFYPDDHITDEDTNTRIAEAIREAALSGLK
NELPHSVAVEVDEILPDPERNGVLAVHAIIYVERVGQKDIIVGHKGQRLGRIIHTSRQDIIKILGQNVFLDLRIKVLKNW
QSDPKALNRLGF
>Mature_332_residues
MLGRPRKPALFCQEVAGSIIPNFQRGFMSFTDTPDGFRSGFVSFVGRPNTGKSTLTNALVGEKIAITANQPETTRHPIRG
LVHRDNAQIIVVDTPGLHRPRTLLGERLNEAVKDTYADVDLIGFTVPANEKIGPGDRWILEAVRKVSPKTPILGIITKAD
SVSRDLVAAQLMAVHELLGGNSEVVPVSSTSGENVETLIKVMTDLLPEGPKFYPDDHITDEDTNTRIAEAIREAALSGLK
NELPHSVAVEVDEILPDPERNGVLAVHAIIYVERVGQKDIIVGHKGQRLGRIIHTSRQDIIKILGQNVFLDLRIKVLKNW
QSDPKALNRLGF

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788919, Length=302, Percent_Identity=35.7615894039735, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI87082120, Length=182, Percent_Identity=28.021978021978, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=163, Percent_Identity=28.8343558282209, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 36435; Mature: 36435

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGRPRKPALFCQEVAGSIIPNFQRGFMSFTDTPDGFRSGFVSFVGRPNTGKSTLTNALV
CCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHH
GEKIAITANQPETTRHPIRGLVHRDNAQIIVVDTPGLHRPRTLLGERLNEAVKDTYADVD
CCEEEEECCCCCCHHHHHHHHEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCE
LIGFTVPANEKIGPGDRWILEAVRKVSPKTPILGIITKADSVSRDLVAAQLMAVHELLGG
EEEEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCC
NSEVVPVSSTSGENVETLIKVMTDLLPEGPKFYPDDHITDEDTNTRIAEAIREAALSGLK
CCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NELPHSVAVEVDEILPDPERNGVLAVHAIIYVERVGQKDIIVGHKGQRLGRIIHTSRQDI
HHCCCHHEEEHHHHCCCCCCCCEEEHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHH
IKILGQNVFLDLRIKVLKNWQSDPKALNRLGF
HHHHCCCEEEEHHHHHHHCCCCCHHHHHHCCC
>Mature Secondary Structure
MLGRPRKPALFCQEVAGSIIPNFQRGFMSFTDTPDGFRSGFVSFVGRPNTGKSTLTNALV
CCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHH
GEKIAITANQPETTRHPIRGLVHRDNAQIIVVDTPGLHRPRTLLGERLNEAVKDTYADVD
CCEEEEECCCCCCHHHHHHHHEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCE
LIGFTVPANEKIGPGDRWILEAVRKVSPKTPILGIITKADSVSRDLVAAQLMAVHELLGG
EEEEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCC
NSEVVPVSSTSGENVETLIKVMTDLLPEGPKFYPDDHITDEDTNTRIAEAIREAALSGLK
CCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NELPHSVAVEVDEILPDPERNGVLAVHAIIYVERVGQKDIIVGHKGQRLGRIIHTSRQDI
HHCCCHHEEEHHHHCCCCCCCCEEEHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHH
IKILGQNVFLDLRIKVLKNWQSDPKALNRLGF
HHHHCCCEEEEHHHHHHHCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]