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The map label for this gene is pimB

Identifier: 62391026

GI number: 62391026

Start: 2289302

End: 2290447

Strand: Reverse

Name: pimB

Synonym: cg2400

Alternate gene names: 62391026

Gene position: 2290447-2289302 (Counterclockwise)

Preceding gene: 62391027

Following gene: 62391025

Centisome position: 69.77

GC content: 56.2

Gene sequence:

>1146_bases
GTGTCTGCATCCCGAAAAACTCTCGTTGTGACCAATGATTTTCCTCCACGGATCGGCGGAATCCAAAGCTATTTGAGGGA
TTTCATCGCTACTCAAGATCCTGAGTCGATCGTGGTGTTTGCGTCGACTCAAAACGCTGAGGAAGCGCATGCCTACGACA
AGACTTTGGACTATGAGGTCATTAGGTGGCCTCGTTCGGTGATGCTGCCCACCCCAACAACGGCACACGCTATGGCGGAG
ATCATTCGTGAGCGAGAGATCGATAATGTGTGGTTCGGTGCTGCGGCTCCGTTGGCGTTGATGGCAGGCACAGCGAAGCA
GGCAGGTGCGAGCAAGGTTATTGCCTCCACTCATGGGCATGAGGTGGGGTGGTCAATGCTTCCTGGATCGAGACAATCGT
TGCGCAAAATCGGCACTGAGGTGGACGTGCTGACTTATATCTCGCAGTACACGCTGCGCAGATTCAAAAGTGCTTTTGGA
TCGCACCCGACTTTTGAACATTTGCCTTCCGGCGTGGACGTTAAGAGATTCACTCCGGCCACGCCAGAGGACAAAAGCGC
AACAAGGAAAAAGCTAGGATTCACGGACACCACCCCGGTTATTGCCTGTAACTCGCGTTTAGTGCCGAGGAAAGGCCAGG
ACTCGCTGATCAAGGCGATGCCACAGGTGATTGCGGCGCGCCCAGATGCGCAGTTGCTCATTGTGGGCAGTGGGCGATAC
GAGTCGACTTTGCGGCGCCTTGCCACTGACGTGAGCCAGAACGTGAAATTCCTTGGGCGCCTTGAATATCAAGATATGAT
CAACACGCTTGCCGCCGCAGATATTTTCGCGATGCCAGCGCGCACCCGCGGTGGCGGACTTGATGTTGAAGGCTTGGGCA
TTGTCTATCTCGAGGCACAAGCCTGCGGAGTGCCGGTGATAGCCGGCACCTCTGGCGGCGCGCCAGAGACGGTGACTCCG
GCAACTGGCCTGGTTGTGGAGGGGTCGGACGTCGATAAGCTGTCTGAGCTTTTAATTGAGCTTCTCGACGATCCGATCCG
CCGCGCCGCGATGGGCGCTGCAGGTAGGGCGCATGTGGAGGCCGAATGGTCGTGGGAAATCATGGGGGAGCGGTTGACCA
ATATTTTGCAGAGTGAACCACGATGA

Upstream 100 bases:

>100_bases
GCCTCAGACTACGGAATCCCTGTGCAGGTGGTATCTGTTGATTCAGCACCGTTTTATGGTGCGCGTCGCTACTAAGAAAT
AGTTCGTCAGGAGAATCTTT

Downstream 100 bases:

>100_bases
TGGTTGGACAGCTGTTGATAGCTATACTTTGAAAGATTAAATTCACCTAAATCCTGTGTAGAACGCGAGGGGCACTCTTA
TGCCACAAAAACCGGCCAGT

Product: glycosyl transferase

Products: NA

Alternate protein names: Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase; Alpha-mannosyltransferase; Alpha-manT; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MSASRKTLVVTNDFPPRIGGIQSYLRDFIATQDPESIVVFASTQNAEEAHAYDKTLDYEVIRWPRSVMLPTPTTAHAMAE
IIREREIDNVWFGAAAPLALMAGTAKQAGASKVIASTHGHEVGWSMLPGSRQSLRKIGTEVDVLTYISQYTLRRFKSAFG
SHPTFEHLPSGVDVKRFTPATPEDKSATRKKLGFTDTTPVIACNSRLVPRKGQDSLIKAMPQVIAARPDAQLLIVGSGRY
ESTLRRLATDVSQNVKFLGRLEYQDMINTLAAADIFAMPARTRGGGLDVEGLGIVYLEAQACGVPVIAGTSGGAPETVTP
ATGLVVEGSDVDKLSELLIELLDDPIRRAAMGAAGRAHVEAEWSWEIMGERLTNILQSEPR

Sequences:

>Translated_381_residues
MSASRKTLVVTNDFPPRIGGIQSYLRDFIATQDPESIVVFASTQNAEEAHAYDKTLDYEVIRWPRSVMLPTPTTAHAMAE
IIREREIDNVWFGAAAPLALMAGTAKQAGASKVIASTHGHEVGWSMLPGSRQSLRKIGTEVDVLTYISQYTLRRFKSAFG
SHPTFEHLPSGVDVKRFTPATPEDKSATRKKLGFTDTTPVIACNSRLVPRKGQDSLIKAMPQVIAARPDAQLLIVGSGRY
ESTLRRLATDVSQNVKFLGRLEYQDMINTLAAADIFAMPARTRGGGLDVEGLGIVYLEAQACGVPVIAGTSGGAPETVTP
ATGLVVEGSDVDKLSELLIELLDDPIRRAAMGAAGRAHVEAEWSWEIMGERLTNILQSEPR
>Mature_380_residues
SASRKTLVVTNDFPPRIGGIQSYLRDFIATQDPESIVVFASTQNAEEAHAYDKTLDYEVIRWPRSVMLPTPTTAHAMAEI
IREREIDNVWFGAAAPLALMAGTAKQAGASKVIASTHGHEVGWSMLPGSRQSLRKIGTEVDVLTYISQYTLRRFKSAFGS
HPTFEHLPSGVDVKRFTPATPEDKSATRKKLGFTDTTPVIACNSRLVPRKGQDSLIKAMPQVIAARPDAQLLIVGSGRYE
STLRRLATDVSQNVKFLGRLEYQDMINTLAAADIFAMPARTRGGGLDVEGLGIVYLEAQACGVPVIAGTSGGAPETVTPA
TGLVVEGSDVDKLSELLIELLDDPIRRAAMGAAGRAHVEAEWSWEIMGERLTNILQSEPR

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 6 of a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) to generate phosphatidyl-myo-inositol bearing alpha-1,2- and alpha-1,6-linked mannose resid

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PIMB_CORGL (Q8NNK8)

Other databases:

- EMBL:   BA000036
- EMBL:   BX927154
- RefSeq:   NP_601390.1
- RefSeq:   YP_226428.1
- PDB:   3OKA
- PDB:   3OKC
- PDB:   3OKP
- PDBsum:   3OKA
- PDBsum:   3OKC
- PDBsum:   3OKP
- ProteinModelPortal:   Q8NNK8
- SMR:   Q8NNK8
- GeneID:   1020138
- GeneID:   3344808
- GenomeReviews:   BA000036_GR
- GenomeReviews:   BX927147_GR
- KEGG:   cgb:cg2400
- KEGG:   cgl:NCgl2106
- HOGENOM:   HBG726846
- OMA:   NDFPPRP
- ProtClustDB:   CLSK633672
- BioCyc:   CGLU196627:CG2400-MONOMER
- InterPro:   IPR001296

Pfam domain/function: PF00534 Glycos_transf_1

EC number: =2.4.1.57

Molecular weight: Translated: 41329; Mature: 41197

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: BINDING 20-20 BINDING 206-206 BINDING 261-261 BINDING 265-265 BINDING 298-298

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASRKTLVVTNDFPPRIGGIQSYLRDFIATQDPESIVVFASTQNAEEAHAYDKTLDYEV
CCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHCCCCHHH
IRWPRSVMLPTPTTAHAMAEIIREREIDNVWFGAAAPLALMAGTAKQAGASKVIASTHGH
HHCCCCEECCCCCHHHHHHHHHHHHCCCCEECCCHHHHHHHHCCHHHCCCHHHHHCCCCC
EVGWSMLPGSRQSLRKIGTEVDVLTYISQYTLRRFKSAFGSHPTFEHLPSGVDVKRFTPA
CCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCC
TPEDKSATRKKLGFTDTTPVIACNSRLVPRKGQDSLIKAMPQVIAARPDAQLLIVGSGRY
CCCCHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCH
ESTLRRLATDVSQNVKFLGRLEYQDMINTLAAADIFAMPARTRGGGLDVEGLGIVYLEAQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEC
ACGVPVIAGTSGGAPETVTPATGLVVEGSDVDKLSELLIELLDDPIRRAAMGAAGRAHVE
CCCCEEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
AEWSWEIMGERLTNILQSEPR
CCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SASRKTLVVTNDFPPRIGGIQSYLRDFIATQDPESIVVFASTQNAEEAHAYDKTLDYEV
CCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHCCCCHHH
IRWPRSVMLPTPTTAHAMAEIIREREIDNVWFGAAAPLALMAGTAKQAGASKVIASTHGH
HHCCCCEECCCCCHHHHHHHHHHHHCCCCEECCCHHHHHHHHCCHHHCCCHHHHHCCCCC
EVGWSMLPGSRQSLRKIGTEVDVLTYISQYTLRRFKSAFGSHPTFEHLPSGVDVKRFTPA
CCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCC
TPEDKSATRKKLGFTDTTPVIACNSRLVPRKGQDSLIKAMPQVIAARPDAQLLIVGSGRY
CCCCHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCH
ESTLRRLATDVSQNVKFLGRLEYQDMINTLAAADIFAMPARTRGGGLDVEGLGIVYLEAQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEC
ACGVPVIAGTSGGAPETVTPATGLVVEGSDVDKLSELLIELLDDPIRRAAMGAAGRAHVE
CCCCEEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
AEWSWEIMGERLTNILQSEPR
CCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626