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The map label for this gene is mraY [H]

Identifier: 62391000

GI number: 62391000

Start: 2258531

End: 2259631

Strand: Reverse

Name: mraY [H]

Synonym: cg2372

Alternate gene names: 62391000

Gene position: 2259631-2258531 (Counterclockwise)

Preceding gene: 62391001

Following gene: 62390999

Centisome position: 68.83

GC content: 53.22

Gene sequence:

>1101_bases
ATGCAACAGATTATGGTCAGTGGAACGGTTGCGTTCCTCGTCTCAATCTTTCTCACCCCGGTGTTGATCCGTTATTTCAC
TAACCGCCAGTTGGGCCAGGAAATCCGTGAAGAAGGCCTGCAGTCTCACTTGCGTAAGCGTGGCACTCCAACCATGGGTG
GCATTGCGATTATCGCGGGCATTGTTGTGGCCTATGTGTTTACCAATATCTTGGCCATGATCCAAGGCGTTGGTGGATTC
ACAGTCTCCGGCTTGCTCGTGTTGGGTCTGACCTTGGGCCTTGGTGCCACTGGTTTCGCCGATGACTTCATCAAGCTGTA
CATGAACCGAAACCTTGGTTTGAACAAGACCGCTAAGCTGGTGTCTCAGCTGGCCATTGCGTTGATCTTTGGTTTTTTGG
TACTGCAGTTTCCCGATGAAAACGGTCTGACCCCAGCATCAACCCACCTGTCATTCATTCGCGATATCGACACCATTGAC
CTTGGCTTCGGGGGCAGCGTTTTTGGCATCATCGTGTTCCTCATCTTTATCTACGTTGTGGTCAGCGCGTGGTCGAATGC
CGTGAACATCACTGACGGTTTGGATGGTTTGGCCGCAGGTACCACAGCATTTGTCATGGGTGCTTACACCTTGATCACGT
TCTGGCAGTTCCGAAACTCCTGCGATACTGCAGTGGAAGCGGGTTGCTATACGGTGCGTGATCCACTGGATTTGTCCGTG
TTGTGTGCTGCTGGTCTGGGCGCCACCTTGGGCTTTCTGTGGTGGAATGCGGCGCCGGCAAAGATCTTCATGGGCGATAC
TGGTTCTTTGGCACTGGGCGGTTTGGTTGCAGGTATTTCTGTGGTTAGTCGCACCGAGCTGCTCATGGTTATCATCGGCG
CGCTGTTTGTCATTGAGATCGCTTCTGTTGCGATCCAGATCGGCGTGTTTAAGACCCGCGGTAAGCGTGTGTTCAAAATG
GCTCCGATCCACCACCACTTCGAGGCCCTTGGGTGGGCTGAAACTACCGTGACCATCCGTTTCTGGCTGATCGCGATCAT
GGCTGTGTTGGCGGGTGTCGGTGTGTTTTACAGCGACTGGCTCCACTTAGCGGAGGTATAA

Upstream 100 bases:

>100_bases
GGTCGCAGAAGCACTACATGGCATGGTGCCGGGCCTCAAAAACACAGGTGGCTCGGTCAACGACGATTCTCGTCGGAACG
TGGAAGGACAGTAGAAAACA

Downstream 100 bases:

>100_bases
ATAATTATGGTTTCTCTGTCCCATTTACCTCAGGCGCTGCAGGGCCGTATTCTTGTGGCCGGCGCTGGTGTTTCCGGCCT
GTCCATTGCAAAGATGCTCA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MQQIMVSGTVAFLVSIFLTPVLIRYFTNRQLGQEIREEGLQSHLRKRGTPTMGGIAIIAGIVVAYVFTNILAMIQGVGGF
TVSGLLVLGLTLGLGATGFADDFIKLYMNRNLGLNKTAKLVSQLAIALIFGFLVLQFPDENGLTPASTHLSFIRDIDTID
LGFGGSVFGIIVFLIFIYVVVSAWSNAVNITDGLDGLAAGTTAFVMGAYTLITFWQFRNSCDTAVEAGCYTVRDPLDLSV
LCAAGLGATLGFLWWNAAPAKIFMGDTGSLALGGLVAGISVVSRTELLMVIIGALFVIEIASVAIQIGVFKTRGKRVFKM
APIHHHFEALGWAETTVTIRFWLIAIMAVLAGVGVFYSDWLHLAEV

Sequences:

>Translated_366_residues
MQQIMVSGTVAFLVSIFLTPVLIRYFTNRQLGQEIREEGLQSHLRKRGTPTMGGIAIIAGIVVAYVFTNILAMIQGVGGF
TVSGLLVLGLTLGLGATGFADDFIKLYMNRNLGLNKTAKLVSQLAIALIFGFLVLQFPDENGLTPASTHLSFIRDIDTID
LGFGGSVFGIIVFLIFIYVVVSAWSNAVNITDGLDGLAAGTTAFVMGAYTLITFWQFRNSCDTAVEAGCYTVRDPLDLSV
LCAAGLGATLGFLWWNAAPAKIFMGDTGSLALGGLVAGISVVSRTELLMVIIGALFVIEIASVAIQIGVFKTRGKRVFKM
APIHHHFEALGWAETTVTIRFWLIAIMAVLAGVGVFYSDWLHLAEV
>Mature_366_residues
MQQIMVSGTVAFLVSIFLTPVLIRYFTNRQLGQEIREEGLQSHLRKRGTPTMGGIAIIAGIVVAYVFTNILAMIQGVGGF
TVSGLLVLGLTLGLGATGFADDFIKLYMNRNLGLNKTAKLVSQLAIALIFGFLVLQFPDENGLTPASTHLSFIRDIDTID
LGFGGSVFGIIVFLIFIYVVVSAWSNAVNITDGLDGLAAGTTAFVMGAYTLITFWQFRNSCDTAVEAGCYTVRDPLDLSV
LCAAGLGATLGFLWWNAAPAKIFMGDTGSLALGGLVAGISVVSRTELLMVIIGALFVIEIASVAIQIGVFKTRGKRVFKM
APIHHHFEALGWAETTVTIRFWLIAIMAVLAGVGVFYSDWLHLAEV

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=351, Percent_Identity=39.6011396011396, Blast_Score=210, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 39269; Mature: 39269

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQIMVSGTVAFLVSIFLTPVLIRYFTNRQLGQEIREEGLQSHLRKRGTPTMGGIAIIAG
CCCEEHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
IVVAYVFTNILAMIQGVGGFTVSGLLVLGLTLGLGATGFADDFIKLYMNRNLGLNKTAKL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHH
VSQLAIALIFGFLVLQFPDENGLTPASTHLSFIRDIDTIDLGFGGSVFGIIVFLIFIYVV
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHH
VSAWSNAVNITDGLDGLAAGTTAFVMGAYTLITFWQFRNSCDTAVEAGCYTVRDPLDLSV
HHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHH
LCAAGLGATLGFLWWNAAPAKIFMGDTGSLALGGLVAGISVVSRTELLMVIIGALFVIEI
HHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASVAIQIGVFKTRGKRVFKMAPIHHHFEALGWAETTVTIRFWLIAIMAVLAGVGVFYSDW
HHHHHHHHHEECCCCEEEEECCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHLAEV
HHHHCC
>Mature Secondary Structure
MQQIMVSGTVAFLVSIFLTPVLIRYFTNRQLGQEIREEGLQSHLRKRGTPTMGGIAIIAG
CCCEEHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
IVVAYVFTNILAMIQGVGGFTVSGLLVLGLTLGLGATGFADDFIKLYMNRNLGLNKTAKL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHH
VSQLAIALIFGFLVLQFPDENGLTPASTHLSFIRDIDTIDLGFGGSVFGIIVFLIFIYVV
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHH
VSAWSNAVNITDGLDGLAAGTTAFVMGAYTLITFWQFRNSCDTAVEAGCYTVRDPLDLSV
HHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHH
LCAAGLGATLGFLWWNAAPAKIFMGDTGSLALGGLVAGISVVSRTELLMVIIGALFVIEI
HHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASVAIQIGVFKTRGKRVFKMAPIHHHFEALGWAETTVTIRFWLIAIMAVLAGVGVFYSDW
HHHHHHHHHEECCCCEEEEECCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHLAEV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA