| Definition | Corynebacterium glutamicum ATCC 13032, complete genome. |
|---|---|
| Accession | NC_006958 |
| Length | 3,282,708 |
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The map label for this gene is murF [H]
Identifier: 62391001
GI number: 62391001
Start: 2259638
End: 2261182
Strand: Reverse
Name: murF [H]
Synonym: cg2373
Alternate gene names: 62391001
Gene position: 2261182-2259638 (Counterclockwise)
Preceding gene: 62391002
Following gene: 62391000
Centisome position: 68.88
GC content: 54.89
Gene sequence:
>1545_bases ATGATCACAATGACCCTTGGGGAAATCGCTGACATCGTTGGAGGCAGGCTTACTGGCGGTGCTCAAGAAGATACGCTTGT GAGCTCCAGCGTGGAGTTTGATTCTCGATCCCTCACACCGGGTGGCTTGTTTTTAGCACTTCCGGGTGCTCGTGTAGACG GCCATGATTTTGCTGCAACTGCAATTGAGAAAGGTGCGGTTGCAGTATTGGCAGCCCGTGAGGTTGACGTACCTGCGATC GTCGTGCCTCCAGTAAAAATCCAGGAATCCAATGCTGACATTTATGCTCATGATCCAGATGGGCATGGCGCGGCGGTAGT GGAGGCGTTGTCTCGGTTGGCTCGCCACGTGGTGGATATCTGCGTGGCTGGCCATCAATTGAACGTTGTGGCTATTACTG GTTCTGCGGGAAAGACTTCTACGAAGGATTTCATCGCGACGGTTCTTGACCAAGATGGGCCAACTGTGGCTCCTCCGGGC TCGTTTAACAATGAGCTTGGTTTGCCACACACCGCGCTCCGCTGCACAACCGATACTAAGTATTTGGTGGCTGAGATGTC CGCGCGTGGCATTGGACATATTAAGCACCTGACAGAGATTGCTCCGCCACGGATTGCAGCTGTGCTCAACGTCGGCCATG CGCACCTGGGTGAATTTGGATCCCGCGAGAATATCGCGCAGGCAAAAGGCGAGATCATTGAAGCGCTGCCCTCGAAGAAA ACGGGTGGGGTAGCAGTCCTTAACGCTGACGATCCTTTTGTCGCCCGGATGGCTCCACGCACTAAGGCGCGCGTGGTGTG GTTTACCACCGATGCAGGCCAAGCAAAAAAGTCTGATTATTGGGCAACGAGTATTTCACTGGACGCTGTTGCGCGGGCAA GCTTTACGCTGAACACGAAGGACGGCTCTTGGCCGGTCACCCTGCAGGTTTTTGGTGAGCACCAGGTTGCTAATGCACTT GCTGCTGCTGCCATTGCCATGGAAGCTGGCGTCGCCCCAGAATTGGTGGTTGCTGGATTGGAAGCACATTCAGCTGCTTC CGCGCACCGCATGGATGTAAAGACCCGTGCCGACGGCGTGACCATCATCAACGATTCTTACAACGCGAATCCTGATTCTA TGCGTGCAGGTATCGCGGCTCTTGCGTACACAGCTAGTGGTCGTTCTGAAGCAACAAGCTGGGCAGTGCTTGGCCAAATG GGTGAGCTTGGCGATGACGCCTCGGAAGCCCATGCCGAACTTGGTGCTGAGCTGGCTAAATACAATGTTCAAGAACTTGT CGCAGTGGGGGAGAACCCTAACTGTGCAGCACTTGCAGAGTCCGCAGCGAGCCTGGGTGTGAGTACTCACGTAGTTTCAG ACGTTGATGCAGCGCTCGAGTTGCTCGCAGGCCATATTAAGCGGGATGATGTAGTGCTGGTTAAGGCTTCAAATGCTGAT CGCCTGTGGAGGGTCGCAGAAGCACTACATGGCATGGTGCCGGGCCTCAAAAACACAGGTGGCTCGGTCAACGACGATTC TCGTCGGAACGTGGAAGGACAGTAG
Upstream 100 bases:
>100_bases CACCCACCATTTTGATGACCGCGAAGAAGTTCGCGCTGCTTTGACAGAAAAGCTCAACAATAAACTTCCCCTTACTACGG AAGAAGGATAGGCCACAGTC
Downstream 100 bases:
>100_bases AAAACAATGCAACAGATTATGGTCAGTGGAACGGTTGCGTTCCTCGTCTCAATCTTTCTCACCCCGGTGTTGATCCGTTA TTTCACTAACCGCCAGTTGG
Product: D-alanine:D-alanine-adding enzyme
Products: NA
Alternate protein names: D-alanyl-D-alanine-adding enzyme; UDP-MurNAc-pentapeptide synthetase [H]
Number of amino acids: Translated: 514; Mature: 514
Protein sequence:
>514_residues MITMTLGEIADIVGGRLTGGAQEDTLVSSSVEFDSRSLTPGGLFLALPGARVDGHDFAATAIEKGAVAVLAAREVDVPAI VVPPVKIQESNADIYAHDPDGHGAAVVEALSRLARHVVDICVAGHQLNVVAITGSAGKTSTKDFIATVLDQDGPTVAPPG SFNNELGLPHTALRCTTDTKYLVAEMSARGIGHIKHLTEIAPPRIAAVLNVGHAHLGEFGSRENIAQAKGEIIEALPSKK TGGVAVLNADDPFVARMAPRTKARVVWFTTDAGQAKKSDYWATSISLDAVARASFTLNTKDGSWPVTLQVFGEHQVANAL AAAAIAMEAGVAPELVVAGLEAHSAASAHRMDVKTRADGVTIINDSYNANPDSMRAGIAALAYTASGRSEATSWAVLGQM GELGDDASEAHAELGAELAKYNVQELVAVGENPNCAALAESAASLGVSTHVVSDVDAALELLAGHIKRDDVVLVKASNAD RLWRVAEALHGMVPGLKNTGGSVNDDSRRNVEGQ
Sequences:
>Translated_514_residues MITMTLGEIADIVGGRLTGGAQEDTLVSSSVEFDSRSLTPGGLFLALPGARVDGHDFAATAIEKGAVAVLAAREVDVPAI VVPPVKIQESNADIYAHDPDGHGAAVVEALSRLARHVVDICVAGHQLNVVAITGSAGKTSTKDFIATVLDQDGPTVAPPG SFNNELGLPHTALRCTTDTKYLVAEMSARGIGHIKHLTEIAPPRIAAVLNVGHAHLGEFGSRENIAQAKGEIIEALPSKK TGGVAVLNADDPFVARMAPRTKARVVWFTTDAGQAKKSDYWATSISLDAVARASFTLNTKDGSWPVTLQVFGEHQVANAL AAAAIAMEAGVAPELVVAGLEAHSAASAHRMDVKTRADGVTIINDSYNANPDSMRAGIAALAYTASGRSEATSWAVLGQM GELGDDASEAHAELGAELAKYNVQELVAVGENPNCAALAESAASLGVSTHVVSDVDAALELLAGHIKRDDVVLVKASNAD RLWRVAEALHGMVPGLKNTGGSVNDDSRRNVEGQ >Mature_514_residues MITMTLGEIADIVGGRLTGGAQEDTLVSSSVEFDSRSLTPGGLFLALPGARVDGHDFAATAIEKGAVAVLAAREVDVPAI VVPPVKIQESNADIYAHDPDGHGAAVVEALSRLARHVVDICVAGHQLNVVAITGSAGKTSTKDFIATVLDQDGPTVAPPG SFNNELGLPHTALRCTTDTKYLVAEMSARGIGHIKHLTEIAPPRIAAVLNVGHAHLGEFGSRENIAQAKGEIIEALPSKK TGGVAVLNADDPFVARMAPRTKARVVWFTTDAGQAKKSDYWATSISLDAVARASFTLNTKDGSWPVTLQVFGEHQVANAL AAAAIAMEAGVAPELVVAGLEAHSAASAHRMDVKTRADGVTIINDSYNANPDSMRAGIAALAYTASGRSEATSWAVLGQM GELGDDASEAHAELGAELAKYNVQELVAVGENPNCAALAESAASLGVSTHVVSDVDAALELLAGHIKRDDVVLVKASNAD RLWRVAEALHGMVPGLKNTGGSVNDDSRRNVEGQ
Specific function: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein [H]
COG id: COG0770
COG function: function code M; UDP-N-acetylmuramyl pentapeptide synthase
Gene ontology:
Cell location: Cytoplasm (Probable) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the MurCDEF family [H]
Homologues:
Organism=Escherichia coli, GI1786274, Length=495, Percent_Identity=34.3434343434343, Blast_Score=189, Evalue=5e-49,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004101 - InterPro: IPR013221 - InterPro: IPR000713 - InterPro: IPR005863 [H]
Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]
EC number: =6.3.2.10 [H]
Molecular weight: Translated: 53266; Mature: 53266
Theoretical pI: Translated: 5.10; Mature: 5.10
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MITMTLGEIADIVGGRLTGGAQEDTLVSSSVEFDSRSLTPGGLFLALPGARVDGHDFAAT CEEEEHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCCHHHH AIEKGAVAVLAAREVDVPAIVVPPVKIQESNADIYAHDPDGHGAAVVEALSRLARHVVDI HHCCCCEEEEEEECCCCCEEEECCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH CVAGHQLNVVAITGSAGKTSTKDFIATVLDQDGPTVAPPGSFNNELGLPHTALRCTTDTK HHCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCC YLVAEMSARGIGHIKHLTEIAPPRIAAVLNVGHAHLGEFGSRENIAQAKGEIIEALPSKK EEHHHHHCCCCHHHHHHHHHCCCHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHCCCCC TGGVAVLNADDPFVARMAPRTKARVVWFTTDAGQAKKSDYWATSISLDAVARASFTLNTK CCCEEEEECCCCEEEECCCCCCEEEEEEECCCCCCCCCCCEEEEEEHHHHEEEEEEEECC DGSWPVTLQVFGEHQVANALAAAAIAMEAGVAPELVVAGLEAHSAASAHRMDVKTRADGV CCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHEECCHHHCCCCHHHEEEEECCCCE TIINDSYNANPDSMRAGIAALAYTASGRSEATSWAVLGQMGELGDDASEAHAELGAELAK EEECCCCCCCHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH YNVQELVAVGENPNCAALAESAASLGVSTHVVSDVDAALELLAGHIKRDDVVLVKASNAD CCHHHHHEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHH RLWRVAEALHGMVPGLKNTGGSVNDDSRRNVEGQ HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure MITMTLGEIADIVGGRLTGGAQEDTLVSSSVEFDSRSLTPGGLFLALPGARVDGHDFAAT CEEEEHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCCHHHH AIEKGAVAVLAAREVDVPAIVVPPVKIQESNADIYAHDPDGHGAAVVEALSRLARHVVDI HHCCCCEEEEEEECCCCCEEEECCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH CVAGHQLNVVAITGSAGKTSTKDFIATVLDQDGPTVAPPGSFNNELGLPHTALRCTTDTK HHCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCC YLVAEMSARGIGHIKHLTEIAPPRIAAVLNVGHAHLGEFGSRENIAQAKGEIIEALPSKK EEHHHHHCCCCHHHHHHHHHCCCHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHCCCCC TGGVAVLNADDPFVARMAPRTKARVVWFTTDAGQAKKSDYWATSISLDAVARASFTLNTK CCCEEEEECCCCEEEECCCCCCEEEEEEECCCCCCCCCCCEEEEEEHHHHEEEEEEEECC DGSWPVTLQVFGEHQVANALAAAAIAMEAGVAPELVVAGLEAHSAASAHRMDVKTRADGV CCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHEECCHHHCCCCHHHEEEEECCCCE TIINDSYNANPDSMRAGIAALAYTASGRSEATSWAVLGQMGELGDDASEAHAELGAELAK EEECCCCCCCHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH YNVQELVAVGENPNCAALAESAASLGVSTHVVSDVDAALELLAGHIKRDDVVLVKASNAD CCHHHHHEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHH RLWRVAEALHGMVPGLKNTGGSVNDDSRRNVEGQ HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12788972 [H]