Click here to switch to the map view.

The map label for this gene is ruvB [H]

Identifier: 62390541

GI number: 62390541

Start: 1762888

End: 1763979

Strand: Reverse

Name: ruvB [H]

Synonym: cg1869

Alternate gene names: 62390541

Gene position: 1763979-1762888 (Counterclockwise)

Preceding gene: 62390542

Following gene: 62390540

Centisome position: 53.74

GC content: 56.14

Gene sequence:

>1092_bases
ATGTCCGATGTGGAAAGAACAGAGTTTGAAATTCCGGGAGGAATTCCACCTCGTCGAAACGGTGGTCAAGGCCGTGCAGC
TGATACCAACGTAGATGCGAACCTGAAGCCTGATGAATACGATGCGGAAGTAACACTTCGTCCGAAGTCTTTGACTGAGT
TTATCGGCCAGCCGAAGGTGCGCGATCAGCTTAGTTTGGTGCTTACCGGTGCGAAAAACCGTGGTGTGGTTCCCGATCAC
GTGTTGTTGTCTGGCCCTCCTGGCCTGGGTAAGACCACCATGGCGATGATTATCGCCCAGGAGTTGGGCACCAGTTTGCG
TATGACCTCAGGCCCAGCCTTGGAACGCGCAGGCGATCTGGCTGCCATGCTGTCCAACCTCATGGAAGGGGACGTGCTGT
TTATTGATGAGATTCACCGCATCGCACGTCCTGCCGAGGAAATGCTGTACATGGCGATGGAAGATTTCCGGATCGATGTC
ATCGTCGGTAAGGGTCCTGGCGCTACCTCAATCCCGCTGGAGATCCCACCCTTTACCCTCGTTGGTGCAACCACCAGGTC
GGGCATGCTCACCGGCCCACTGCGTGACCGTTTCGGTTTTACCGCGCAGATGGAATTCTACGATGTGCCTGATCTGACCA
AAGTGGTGAAACGAACAGCTAAGATCCTCGATGTCGGAATCGACAACGATGCCGCCGTGGAAATTGCCTCGCGGTCTCGT
GGTACTCCTCGTATTGCTAACCGACTGCTTCGTCGAGTCCGTGACTTCGCTGAAGTTCATGCGGATGGTCACATCACGAT
GGGTGCTGCCAATGCTGCGCTGGTTGTATTCGATGTCGATGAAGTCGGACTCGATCGCCTGGATAGGGCAGTGCTTGATG
CCTTGATCCGCGGACATGGCGGAGGCCCTGTTGGCGTGAACACACTCGCGGTTGCAGTTGGTGAAGAACCCGGCACTGTG
GAAGAAGTATGCGAGCCCTATTTGGTGCGTGCCGGCATGATTGCACGAACCGGACGGGGACGCGTGGCAACCGCAGCTGC
ATGGAGACACCTGGGGCTGGAACCACCAGAAGGCACCATCGGCGATTATTAG

Upstream 100 bases:

>100_bases
AGATGATGCAGTGAGCTTTGTGCTGGCGGCGGATCCATCCTTGGACACCAGTGGCGCGCTTCGTGCCGCATTGGCAAAAC
TCAGCGGAAAGTAGACCCTC

Downstream 100 bases:

>100_bases
CCACCTTAGGTGGCCAGGATGTTCCATGGTCTGGCAAACTAACTAACCATGGACATCGTTTTCCTCATAATTCTTCTAGC
CATTTTTATCGTTCCCACTT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSDVERTEFEIPGGIPPRRNGGQGRAADTNVDANLKPDEYDAEVTLRPKSLTEFIGQPKVRDQLSLVLTGAKNRGVVPDH
VLLSGPPGLGKTTMAMIIAQELGTSLRMTSGPALERAGDLAAMLSNLMEGDVLFIDEIHRIARPAEEMLYMAMEDFRIDV
IVGKGPGATSIPLEIPPFTLVGATTRSGMLTGPLRDRFGFTAQMEFYDVPDLTKVVKRTAKILDVGIDNDAAVEIASRSR
GTPRIANRLLRRVRDFAEVHADGHITMGAANAALVVFDVDEVGLDRLDRAVLDALIRGHGGGPVGVNTLAVAVGEEPGTV
EEVCEPYLVRAGMIARTGRGRVATAAAWRHLGLEPPEGTIGDY

Sequences:

>Translated_363_residues
MSDVERTEFEIPGGIPPRRNGGQGRAADTNVDANLKPDEYDAEVTLRPKSLTEFIGQPKVRDQLSLVLTGAKNRGVVPDH
VLLSGPPGLGKTTMAMIIAQELGTSLRMTSGPALERAGDLAAMLSNLMEGDVLFIDEIHRIARPAEEMLYMAMEDFRIDV
IVGKGPGATSIPLEIPPFTLVGATTRSGMLTGPLRDRFGFTAQMEFYDVPDLTKVVKRTAKILDVGIDNDAAVEIASRSR
GTPRIANRLLRRVRDFAEVHADGHITMGAANAALVVFDVDEVGLDRLDRAVLDALIRGHGGGPVGVNTLAVAVGEEPGTV
EEVCEPYLVRAGMIARTGRGRVATAAAWRHLGLEPPEGTIGDY
>Mature_362_residues
SDVERTEFEIPGGIPPRRNGGQGRAADTNVDANLKPDEYDAEVTLRPKSLTEFIGQPKVRDQLSLVLTGAKNRGVVPDHV
LLSGPPGLGKTTMAMIIAQELGTSLRMTSGPALERAGDLAAMLSNLMEGDVLFIDEIHRIARPAEEMLYMAMEDFRIDVI
VGKGPGATSIPLEIPPFTLVGATTRSGMLTGPLRDRFGFTAQMEFYDVPDLTKVVKRTAKILDVGIDNDAAVEIASRSRG
TPRIANRLLRRVRDFAEVHADGHITMGAANAALVVFDVDEVGLDRLDRAVLDALIRGHGGGPVGVNTLAVAVGEEPGTVE
EVCEPYLVRAGMIARTGRGRVATAAAWRHLGLEPPEGTIGDY

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=331, Percent_Identity=55.2870090634441, Blast_Score=373, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 38891; Mature: 38760

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVERTEFEIPGGIPPRRNGGQGRAADTNVDANLKPDEYDAEVTLRPKSLTEFIGQPKV
CCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHCCCCH
RDQLSLVLTGAKNRGVVPDHVLLSGPPGLGKTTMAMIIAQELGTSLRMTSGPALERAGDL
HCCEEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHH
AAMLSNLMEGDVLFIDEIHRIARPAEEMLYMAMEDFRIDVIVGKGPGATSIPLEIPPFTL
HHHHHHHHCCCEEEHHHHHHHHCCHHHHHHHHHHCCEEEEEEECCCCCCCCCEECCCEEE
VGATTRSGMLTGPLRDRFGFTAQMEFYDVPDLTKVVKRTAKILDVGIDNDAAVEIASRSR
EECCCCCCEEECCHHHHCCCEEEEEEECCCHHHHHHHHHHHHHEECCCCCCEEEECCCCC
GTPRIANRLLRRVRDFAEVHADGHITMGAANAALVVFDVDEVGLDRLDRAVLDALIRGHG
CCHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEEECHHHCHHHHHHHHHHHHHHCCC
GGPVGVNTLAVAVGEEPGTVEEVCEPYLVRAGMIARTGRGRVATAAAWRHLGLEPPEGTI
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHCCCCCCCCCC
GDY
CCC
>Mature Secondary Structure 
SDVERTEFEIPGGIPPRRNGGQGRAADTNVDANLKPDEYDAEVTLRPKSLTEFIGQPKV
CCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHCCCCH
RDQLSLVLTGAKNRGVVPDHVLLSGPPGLGKTTMAMIIAQELGTSLRMTSGPALERAGDL
HCCEEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHH
AAMLSNLMEGDVLFIDEIHRIARPAEEMLYMAMEDFRIDVIVGKGPGATSIPLEIPPFTL
HHHHHHHHCCCEEEHHHHHHHHCCHHHHHHHHHHCCEEEEEEECCCCCCCCCEECCCEEE
VGATTRSGMLTGPLRDRFGFTAQMEFYDVPDLTKVVKRTAKILDVGIDNDAAVEIASRSR
EECCCCCCEEECCHHHHCCCEEEEEEECCCHHHHHHHHHHHHHEECCCCCCEEEECCCCC
GTPRIANRLLRRVRDFAEVHADGHITMGAANAALVVFDVDEVGLDRLDRAVLDALIRGHG
CCHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEEECHHHCHHHHHHHHHHHHHHCCC
GGPVGVNTLAVAVGEEPGTVEEVCEPYLVRAGMIARTGRGRVATAAAWRHLGLEPPEGTI
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHCCCCCCCCCC
GDY
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA