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The map label for this gene is pepQ [H]

Identifier: 62390503

GI number: 62390503

Start: 1718246

End: 1719337

Strand: Reverse

Name: pepQ [H]

Synonym: cg1826

Alternate gene names: 62390503

Gene position: 1719337-1718246 (Counterclockwise)

Preceding gene: 62390504

Following gene: 62390502

Centisome position: 52.38

GC content: 58.52

Gene sequence:

>1092_bases
ATGGCTTTGGCTGATACCCGATTTGCCACTCGTCGTCGCGCACTTGCCGCAAAACTGGCAGCTCAACGGATCGACTCAAT
TTTGGTGACAAGCCCGATCCATGTTCGCTATCTCAGCGGATTCACCGGCTCCAACGGCGCACTGATCGTGAACAAAGATC
TCTCCGCGCAGATCTGCACCGACGGTCGCTACACCACCCAGATCGCAGAAGAAGTCCCGGACATCGAGGCGCTGATTGAG
CGTGCCTCGGCAACGACGCTGCTAGCGCAGGTCGAAGGGCCGCGTCGTATAGCAATCGAAGCCGCACAAACCACCCTGGA
CCAGCTAGACAGCCTGCGTGAAGCAACCCAGGAAGACGTCGAGCTGATCCCCGTGTCAGGTGTTGTGGAATCCATTCGCC
TGACCAAAGACAGCTTCGAACTCGACCGCCTCCGCGATGTCGCAGCGCTGGCTTCCCAAGCATTCGAAGATTTACTCGCA
GCAGGAGAACTCGCCGAAGGCCGATCAGAGCGCCAAGTCGCCGCCGATCTGGAATACCGCATGCGCCTGTTGGGAGCAGA
ACGCCCCAGCTTCGACACCATCGTGGCCTCTGGACCTAACTCCGCGAAACCACACCACGGCGCAGGCGACCGCATCCTCC
AGCGCGGCGATCTAGTCACCATCGATTTCGGCGCACACGCACGCGGATTCAACTCCGATATGACCCGCACCCTCGTTATG
GGCGAAGCAGGGGAGTTCGAAGCAGAAATCTACGACATCGTCCTGCGCTCCCAACTCGCTGGTGTTGAAGCAGCCTACTC
AGGCGCCAACCTCTTCGACATCGACGCAGCATGCCGCAAAATCATCGAAGACGCAGGCTACGGCGAATACTTCGTGCACT
CCACCGGCCACGGCATCGGACTTGAAGTCCACGAAGCCCCAAGCGCATCCAAAACCTCACAAGGAGTCCTAGAAACCGGC
TCCACACTGACCATCGAACCCGGAATTTACGTCCCCGGAAAGGGCGGCGTACGCATCGAAGACACCCTGATTATTACCTC
AGGAGCACCGGAAATCATCACCAAGGTGAGTAAGGACCTCATCGTGGTGTAA

Upstream 100 bases:

>100_bases
TTTACAGAGTGCTTATGAGGCAATCAGCCACTAAGTGTTGAGTAATCTACTAGTTTGGACTAGAAGTTACCCACTTTCAG
TGAATTTTTAAGGAGAGAAC

Downstream 100 bases:

>100_bases
TCTAGGTGAGCTAATCGGTCTGCGCGTTTTTCAAGCACTTTGCGCAGACCCCCATCCACGTAATCCACGAGGGAGATCAC
ATCCGTGGCAACTACCGCTG

Product: XAA-Pro aminopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MALADTRFATRRRALAAKLAAQRIDSILVTSPIHVRYLSGFTGSNGALIVNKDLSAQICTDGRYTTQIAEEVPDIEALIE
RASATTLLAQVEGPRRIAIEAAQTTLDQLDSLREATQEDVELIPVSGVVESIRLTKDSFELDRLRDVAALASQAFEDLLA
AGELAEGRSERQVAADLEYRMRLLGAERPSFDTIVASGPNSAKPHHGAGDRILQRGDLVTIDFGAHARGFNSDMTRTLVM
GEAGEFEAEIYDIVLRSQLAGVEAAYSGANLFDIDAACRKIIEDAGYGEYFVHSTGHGIGLEVHEAPSASKTSQGVLETG
STLTIEPGIYVPGKGGVRIEDTLIITSGAPEIITKVSKDLIVV

Sequences:

>Translated_363_residues
MALADTRFATRRRALAAKLAAQRIDSILVTSPIHVRYLSGFTGSNGALIVNKDLSAQICTDGRYTTQIAEEVPDIEALIE
RASATTLLAQVEGPRRIAIEAAQTTLDQLDSLREATQEDVELIPVSGVVESIRLTKDSFELDRLRDVAALASQAFEDLLA
AGELAEGRSERQVAADLEYRMRLLGAERPSFDTIVASGPNSAKPHHGAGDRILQRGDLVTIDFGAHARGFNSDMTRTLVM
GEAGEFEAEIYDIVLRSQLAGVEAAYSGANLFDIDAACRKIIEDAGYGEYFVHSTGHGIGLEVHEAPSASKTSQGVLETG
STLTIEPGIYVPGKGGVRIEDTLIITSGAPEIITKVSKDLIVV
>Mature_362_residues
ALADTRFATRRRALAAKLAAQRIDSILVTSPIHVRYLSGFTGSNGALIVNKDLSAQICTDGRYTTQIAEEVPDIEALIER
ASATTLLAQVEGPRRIAIEAAQTTLDQLDSLREATQEDVELIPVSGVVESIRLTKDSFELDRLRDVAALASQAFEDLLAA
GELAEGRSERQVAADLEYRMRLLGAERPSFDTIVASGPNSAKPHHGAGDRILQRGDLVTIDFGAHARGFNSDMTRTLVMG
EAGEFEAEIYDIVLRSQLAGVEAAYSGANLFDIDAACRKIIEDAGYGEYFVHSTGHGIGLEVHEAPSASKTSQGVLETGS
TLTIEPGIYVPGKGGVRIEDTLIITSGAPEIITKVSKDLIVV

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=311, Percent_Identity=26.6881028938907, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI264681563, Length=165, Percent_Identity=34.5454545454545, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI93141226, Length=169, Percent_Identity=36.094674556213, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI260593665, Length=292, Percent_Identity=26.027397260274, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI149589008, Length=292, Percent_Identity=26.3698630136986, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI264681565, Length=162, Percent_Identity=32.0987654320988, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1788728, Length=359, Percent_Identity=36.4902506963788, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI1789275, Length=278, Percent_Identity=27.6978417266187, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1786364, Length=183, Percent_Identity=29.5081967213115, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17509539, Length=259, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320922, Length=248, Percent_Identity=25.4032258064516, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321118, Length=292, Percent_Identity=23.972602739726, Blast_Score=73, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6322999, Length=167, Percent_Identity=31.1377245508982, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19920384, Length=295, Percent_Identity=28.135593220339, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17137632, Length=377, Percent_Identity=24.9336870026525, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 38877; Mature: 38746

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALADTRFATRRRALAAKLAAQRIDSILVTSPIHVRYLSGFTGSNGALIVNKDLSAQICT
CCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCEECCCCEEEEECCCCEEEEC
DGRYTTQIAEEVPDIEALIERASATTLLAQVEGPRRIAIEAAQTTLDQLDSLREATQEDV
CCCHHHHHHHHCCCHHHHHHHHHHHEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHCC
ELIPVSGVVESIRLTKDSFELDRLRDVAALASQAFEDLLAAGELAEGRSERQVAADLEYR
EEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHH
MRLLGAERPSFDTIVASGPNSAKPHHGAGDRILQRGDLVTIDFGAHARGFNSDMTRTLVM
HHHHCCCCCCCCEEEECCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCEEEEE
GEAGEFEAEIYDIVLRSQLAGVEAAYSGANLFDIDAACRKIIEDAGYGEYFVHSTGHGIG
CCCCCHHHHHHHHHHHHHHCCCHHHCCCCCEEEHHHHHHHHHHHCCCCCEEEEECCCCCE
LEVHEAPSASKTSQGVLETGSTLTIEPGIYVPGKGGVRIEDTLIITSGAPEIITKVSKDL
EEEECCCCCCCCCCCHHHCCCEEEECCCEEECCCCCEEEEEEEEEECCCHHHHHHHHHCE
IVV
ECC
>Mature Secondary Structure 
ALADTRFATRRRALAAKLAAQRIDSILVTSPIHVRYLSGFTGSNGALIVNKDLSAQICT
CCCCCHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCEECCCCEEEEECCCCEEEEC
DGRYTTQIAEEVPDIEALIERASATTLLAQVEGPRRIAIEAAQTTLDQLDSLREATQEDV
CCCHHHHHHHHCCCHHHHHHHHHHHEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHCC
ELIPVSGVVESIRLTKDSFELDRLRDVAALASQAFEDLLAAGELAEGRSERQVAADLEYR
EEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHH
MRLLGAERPSFDTIVASGPNSAKPHHGAGDRILQRGDLVTIDFGAHARGFNSDMTRTLVM
HHHHCCCCCCCCEEEECCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCEEEEE
GEAGEFEAEIYDIVLRSQLAGVEAAYSGANLFDIDAACRKIIEDAGYGEYFVHSTGHGIG
CCCCCHHHHHHHHHHHHHHCCCHHHCCCCCEEEHHHHHHHHHHHCCCCCEEEEECCCCCE
LEVHEAPSASKTSQGVLETGSTLTIEPGIYVPGKGGVRIEDTLIITSGAPEIITKVSKDL
EEEECCCCCCCCCCCHHHCCCEEEECCCEEECCCCCEEEEEEEEEECCCHHHHHHHHHCE
IVV
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]