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The map label for this gene is aroB [H]

Identifier: 62390504

GI number: 62390504

Start: 1719404

End: 1720501

Strand: Reverse

Name: aroB [H]

Synonym: cg1827

Alternate gene names: 62390504

Gene position: 1720501-1719404 (Counterclockwise)

Preceding gene: 62390505

Following gene: 62390503

Centisome position: 52.41

GC content: 58.47

Gene sequence:

>1098_bases
ATGAGCGCAGTGCAGATTTTCAACACCGTCCACGTCAATGGATCTTCCCCCTATGATGTCCACATTGGTTCCGGCCTCAA
CGAGCTCATTGTTCAGCGCGCAGCGGAATCAGGCGCGGAGCAGGTAGCGATTTTGCACCAGCCCAGCATGGATGACATTG
CATCCGAGTTGGATGCAGCACTAGTCGCTGCTGGTTTGAAGGTCCTGCACCTTAATGTTCCCGATGCGGAAAACGGCAAG
TCCTTGGAAGTAGCGGGGCAGTGCTGGGATGAATTGGGTGGCGCAGCATTCGGCCGCCGCGATATCGTCATCGGACTTGG
TGGCGGTGCTGCCACAGATCTCGCGGGATTCGTCGCTGCTGCATGGATGCGTGGCGTGCGCGTCATTCAGGTTCCAACCA
CCTTGTTGGCCATGGTGGACGCTGCGGTGGGCGGCAAGACTGGCATCAATACCGCCGCAGGCAAGAACCTTGTGGGCGCG
TTCCACGAGCCTGACGCAGTATTCATTGACACCGATCGCCTAGCCACCCTGCCTGACGCGGAAATCATCGCGGGATCCGC
CGAAATCATCAAAACTGGTTTCATCGCCGACCCAGAAATCCTGCGCCTTTACGAAACTGATCCCGCAGCCTGCCTGAAGA
AAGAAGTCGAAGGCTCCCACCTACCTGAACTGATTTGGCGCTCCGTCACCGTCAAGGGCTCCGTGGTCGGCCAAGACCTC
AAAGAATCTAGCCTGCGCGAAATCCTCAACTACGGACACACCTTTGCCCACGCCGTCGAACTCCGCGAAAACTTCCGCTG
GCGCCACGGCAATGCCGTTGCAGTGGGCATGATGTTCATCGCCAACCTCTCCCACAAGCTCGGGCTTATCGACGCGCCCC
TCCTCGAGCGCCACCGCTCAATCCTGGCGGCCATCGGTCTGCCCACTTCCTACGAAGGCGGAGCCTTCGACGAGCTTTAC
GACGGTATGACCCGCGACAAGAAAAACCGCGACGGCAACATCCGCTTCGTCGCACTGACCGCCGTGGGCGAGGTTACCCG
CATTGAGGGGCCCTCAAAACAAGATTTACAGAGTGCTTATGAGGCAATCAGCCACTAA

Upstream 100 bases:

>100_bases
CAGTGTTGCATCATCTAGAAATCGATTAATTAAACCGGGCACCTGATTAACATTGGGCTGCCCGGTTTCTTCCTATTACA
AGCGAAAGGCAACGTGCCCC

Downstream 100 bases:

>100_bases
GTGTTGAGTAATCTACTAGTTTGGACTAGAAGTTACCCACTTTCAGTGAATTTTTAAGGAGAGAACATGGCTTTGGCTGA
TACCCGATTTGCCACTCGTC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MSAVQIFNTVHVNGSSPYDVHIGSGLNELIVQRAAESGAEQVAILHQPSMDDIASELDAALVAAGLKVLHLNVPDAENGK
SLEVAGQCWDELGGAAFGRRDIVIGLGGGAATDLAGFVAAAWMRGVRVIQVPTTLLAMVDAAVGGKTGINTAAGKNLVGA
FHEPDAVFIDTDRLATLPDAEIIAGSAEIIKTGFIADPEILRLYETDPAACLKKEVEGSHLPELIWRSVTVKGSVVGQDL
KESSLREILNYGHTFAHAVELRENFRWRHGNAVAVGMMFIANLSHKLGLIDAPLLERHRSILAAIGLPTSYEGGAFDELY
DGMTRDKKNRDGNIRFVALTAVGEVTRIEGPSKQDLQSAYEAISH

Sequences:

>Translated_365_residues
MSAVQIFNTVHVNGSSPYDVHIGSGLNELIVQRAAESGAEQVAILHQPSMDDIASELDAALVAAGLKVLHLNVPDAENGK
SLEVAGQCWDELGGAAFGRRDIVIGLGGGAATDLAGFVAAAWMRGVRVIQVPTTLLAMVDAAVGGKTGINTAAGKNLVGA
FHEPDAVFIDTDRLATLPDAEIIAGSAEIIKTGFIADPEILRLYETDPAACLKKEVEGSHLPELIWRSVTVKGSVVGQDL
KESSLREILNYGHTFAHAVELRENFRWRHGNAVAVGMMFIANLSHKLGLIDAPLLERHRSILAAIGLPTSYEGGAFDELY
DGMTRDKKNRDGNIRFVALTAVGEVTRIEGPSKQDLQSAYEAISH
>Mature_364_residues
SAVQIFNTVHVNGSSPYDVHIGSGLNELIVQRAAESGAEQVAILHQPSMDDIASELDAALVAAGLKVLHLNVPDAENGKS
LEVAGQCWDELGGAAFGRRDIVIGLGGGAATDLAGFVAAAWMRGVRVIQVPTTLLAMVDAAVGGKTGINTAAGKNLVGAF
HEPDAVFIDTDRLATLPDAEIIAGSAEIIKTGFIADPEILRLYETDPAACLKKEVEGSHLPELIWRSVTVKGSVVGQDLK
ESSLREILNYGHTFAHAVELRENFRWRHGNAVAVGMMFIANLSHKLGLIDAPLLERHRSILAAIGLPTSYEGGAFDELYD
GMTRDKKNRDGNIRFVALTAVGEVTRIEGPSKQDLQSAYEAISH

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=335, Percent_Identity=38.5074626865672, Blast_Score=189, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6320332, Length=369, Percent_Identity=33.3333333333333, Blast_Score=183, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 38859; Mature: 38727

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVQIFNTVHVNGSSPYDVHIGSGLNELIVQRAAESGAEQVAILHQPSMDDIASELDAA
CCCEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHH
LVAAGLKVLHLNVPDAENGKSLEVAGQCWDELGGAAFGRRDIVIGLGGGAATDLAGFVAA
HHHCCEEEEEEECCCCCCCCEEEHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHH
AWMRGVRVIQVPTTLLAMVDAAVGGKTGINTAAGKNLVGAFHEPDAVFIDTDRLATLPDA
HHHCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCEEEEECCCCCCCCCH
EIIAGSAEIIKTGFIADPEILRLYETDPAACLKKEVEGSHLPELIWRSVTVKGSVVGQDL
HHCCCCHHHHHHCCCCCHHHEEEECCCHHHHHHHHCCCCCHHHHHHHHHEEECHHHCCHH
KESSLREILNYGHTFAHAVELRENFRWRHGNAVAVGMMFIANLSHKLGLIDAPLLERHRS
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ILAAIGLPTSYEGGAFDELYDGMTRDKKNRDGNIRFVALTAVGEVTRIEGPSKQDLQSAY
HHHHHCCCCCCCCCCHHHHHCCHHCCCCCCCCCEEEEEEEECCCCEECCCCCHHHHHHHH
EAISH
HHHCC
>Mature Secondary Structure 
SAVQIFNTVHVNGSSPYDVHIGSGLNELIVQRAAESGAEQVAILHQPSMDDIASELDAA
CCEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHH
LVAAGLKVLHLNVPDAENGKSLEVAGQCWDELGGAAFGRRDIVIGLGGGAATDLAGFVAA
HHHCCEEEEEEECCCCCCCCEEEHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHH
AWMRGVRVIQVPTTLLAMVDAAVGGKTGINTAAGKNLVGAFHEPDAVFIDTDRLATLPDA
HHHCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCEEEEECCCCCCCCCH
EIIAGSAEIIKTGFIADPEILRLYETDPAACLKKEVEGSHLPELIWRSVTVKGSVVGQDL
HHCCCCHHHHHHCCCCCHHHEEEECCCHHHHHHHHCCCCCHHHHHHHHHEEECHHHCCHH
KESSLREILNYGHTFAHAVELRENFRWRHGNAVAVGMMFIANLSHKLGLIDAPLLERHRS
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ILAAIGLPTSYEGGAFDELYDGMTRDKKNRDGNIRFVALTAVGEVTRIEGPSKQDLQSAY
HHHHHCCCCCCCCCCHHHHHCCHHCCCCCCCCCEEEEEEEECCCCEECCCCCHHHHHHHH
EAISH
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA