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The map label for this gene is ribH [H]

Identifier: 62390476

GI number: 62390476

Start: 1691334

End: 1691813

Strand: Reverse

Name: ribH [H]

Synonym: cg1797

Alternate gene names: 62390476

Gene position: 1691813-1691334 (Counterclockwise)

Preceding gene: 62390477

Following gene: 62390475

Centisome position: 51.54

GC content: 57.92

Gene sequence:

>480_bases
ATGGCTAAAGAAGGATTGCCGGCAGTCGAACTCCCCGACGCCAGCGGATTAAAAGTCGCCGTAGTCACCGCACGGTGGAA
CGCAGAAATCTGCGACCGCCTGCACAAGCACGCAGTAGATGCGGGACGTGCAGCAGGAGCAACGGTGAGCGAATACCGCG
TCATCGGCGCCCTGGAACTTCCAGTCGTAGTGCAAGAACTGGCACGCACCCATGACGCAGTAGTTGCCTTGGGCTGTGTC
GTTCGTGGCGGCACCCCACACTTTGATTACGTGTGCGACTCTGTCACCGAAGGCCTCACCCGCATTGCTCTTGATACTTC
CACCCCAATCGGCAACGGTGTGTTGACTACCAACACCGAAGAGCAAGCCGTGGAACGCTCCGGTGGAGAAGGCTCTGTAG
AGGACAAAGGCGCAGAGGCAATGGTCGCTGCACTCGATACTGCCCTCGTGCTTTCTCAAATTCGTGCAACTGAGGGTTAG

Upstream 100 bases:

>100_bases
ATGTTCGATACCTGAAAACCAAGCGTGACCGCATGGGACATGACCTCCCAGATGTCGCACTGTGGGAACAAGAGCACCCA
GAAAACTAAGGAGCACAACA

Downstream 100 bases:

>100_bases
ACTGTTCTTTAAAAGGTTTGACGCCTCGGTTTAATGCCTAGCAGGATGCGCGCCACCGCTAATTAGTTCTAAGGATTTGT
GAAATCGTGACAACCAACGC

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MAKEGLPAVELPDASGLKVAVVTARWNAEICDRLHKHAVDAGRAAGATVSEYRVIGALELPVVVQELARTHDAVVALGCV
VRGGTPHFDYVCDSVTEGLTRIALDTSTPIGNGVLTTNTEEQAVERSGGEGSVEDKGAEAMVAALDTALVLSQIRATEG

Sequences:

>Translated_159_residues
MAKEGLPAVELPDASGLKVAVVTARWNAEICDRLHKHAVDAGRAAGATVSEYRVIGALELPVVVQELARTHDAVVALGCV
VRGGTPHFDYVCDSVTEGLTRIALDTSTPIGNGVLTTNTEEQAVERSGGEGSVEDKGAEAMVAALDTALVLSQIRATEG
>Mature_158_residues
AKEGLPAVELPDASGLKVAVVTARWNAEICDRLHKHAVDAGRAAGATVSEYRVIGALELPVVVQELARTHDAVVALGCVV
RGGTPHFDYVCDSVTEGLTRIALDTSTPIGNGVLTTNTEEQAVERSGGEGSVEDKGAEAMVAALDTALVLSQIRATEG

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=154, Percent_Identity=43.5064935064935, Blast_Score=108, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324429, Length=168, Percent_Identity=32.1428571428571, Blast_Score=77, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16476; Mature: 16345

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEGLPAVELPDASGLKVAVVTARWNAEICDRLHKHAVDAGRAAGATVSEYRVIGALEL
CCCCCCCCEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHEECHHHH
PVVVQELARTHDAVVALGCVVRGGTPHFDYVCDSVTEGLTRIALDTSTPIGNGVLTTNTE
HHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCH
EQAVERSGGEGSVEDKGAEAMVAALDTALVLSQIRATEG
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKEGLPAVELPDASGLKVAVVTARWNAEICDRLHKHAVDAGRAAGATVSEYRVIGALEL
CCCCCCCEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHEECHHHH
PVVVQELARTHDAVVALGCVVRGGTPHFDYVCDSVTEGLTRIALDTSTPIGNGVLTTNTE
HHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCH
EQAVERSGGEGSVEDKGAEAMVAALDTALVLSQIRATEG
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12840036 [H]