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The map label for this gene is zupT [H]

Identifier: 62390318

GI number: 62390318

Start: 1513641

End: 1514447

Strand: Direct

Name: zupT [H]

Synonym: cg1623

Alternate gene names: 62390318

Gene position: 1513641-1514447 (Clockwise)

Preceding gene: 62390317

Following gene: 62390323

Centisome position: 46.11

GC content: 57.99

Gene sequence:

>807_bases
ATGGATACCTCGACTGTGTTGTTCGCATTTGGACTCACCCTATTTGCCGGTCTTGCCACCGGCATCGGCGGTCTCATCGC
CGTAGCGCGCAAAACCGTCACCGAAGGATTCCTCGCAGGATCACTCGGCTTCTCTGTCGGCGTGATGCTGTACGTATCCT
TTGTGGAAATTCTACCCGGCGCCTTTGATGAATTAACCAGTGTTTGGGGAGAAAAAGGCGGAAGTTGGGCCGCTGTTATC
GGCTTCTTCGGTGGCATCGCGCTGATCGCCATCATCGACCGCTTAGTCCCCACGGCGATTAACCCCCACGAGCCCTCCAC
CGTGGGAGGCGCCGTTGAAGGATTCGAGCGCCGCAACCGCATGATGAAAATGGGTGTGCTCACTGCGCTGGCCATCGCGA
TCCACAACTTTCCCGAAGGTTTCGCTACATTCTTGGCCGGATTGTCCGATCCAATGATCGCGATCCCTGTGGCCGTGGCA
ATTGCCATTCACAATATTCCAGAGGGCATTGCGGTGGCGGTGCCACTGAGGGAAGCTACAGGGTCACGTCGAAAAGCATT
AGGTTGGGCGACCCTCTCCGGCCTTGCTGAGCCCGCCGGCGCCCTCATCGGATTCCTGCTGCTCATGCCCTTTATCGGAC
CAGAAGCACTCGGCCTGTGCTTCGCCGCAGTTGCCGGCGTGATGGTGTTCATCAGCGTCGATGAACTACTGCCCACTGCC
ATCTCCAGCGGCAAACACCACACCGCCATCTACGGACTCATCGCTGGCATGGCAGTCATGGCGATCAGCCTGCTGCTGTT
TATCTAG

Upstream 100 bases:

>100_bases
AGTTATTGGATCACGGGGGTATTTATCAGCGTCTGTGGACTGCGTGGAGTGTCGGAAGATAGTTGACTGTTCAATGCGTT
GAACATTAGTATTCATCCCT

Downstream 100 bases:

>100_bases
CGTTCAGCCGCAACAAGCATCCGGTCAATGTTGGTCAACACCTCATCAACATAGGCCGGATTAACGCCGCGCTCCCGCCG
CGCCTTCAACAGCTCCTCCT

Product: zinc transporter ZupT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MDTSTVLFAFGLTLFAGLATGIGGLIAVARKTVTEGFLAGSLGFSVGVMLYVSFVEILPGAFDELTSVWGEKGGSWAAVI
GFFGGIALIAIIDRLVPTAINPHEPSTVGGAVEGFERRNRMMKMGVLTALAIAIHNFPEGFATFLAGLSDPMIAIPVAVA
IAIHNIPEGIAVAVPLREATGSRRKALGWATLSGLAEPAGALIGFLLLMPFIGPEALGLCFAAVAGVMVFISVDELLPTA
ISSGKHHTAIYGLIAGMAVMAISLLLFI

Sequences:

>Translated_268_residues
MDTSTVLFAFGLTLFAGLATGIGGLIAVARKTVTEGFLAGSLGFSVGVMLYVSFVEILPGAFDELTSVWGEKGGSWAAVI
GFFGGIALIAIIDRLVPTAINPHEPSTVGGAVEGFERRNRMMKMGVLTALAIAIHNFPEGFATFLAGLSDPMIAIPVAVA
IAIHNIPEGIAVAVPLREATGSRRKALGWATLSGLAEPAGALIGFLLLMPFIGPEALGLCFAAVAGVMVFISVDELLPTA
ISSGKHHTAIYGLIAGMAVMAISLLLFI
>Mature_268_residues
MDTSTVLFAFGLTLFAGLATGIGGLIAVARKTVTEGFLAGSLGFSVGVMLYVSFVEILPGAFDELTSVWGEKGGSWAAVI
GFFGGIALIAIIDRLVPTAINPHEPSTVGGAVEGFERRNRMMKMGVLTALAIAIHNFPEGFATFLAGLSDPMIAIPVAVA
IAIHNIPEGIAVAVPLREATGSRRKALGWATLSGLAEPAGALIGFLLLMPFIGPEALGLCFAAVAGVMVFISVDELLPTA
ISSGKHHTAIYGLIAGMAVMAISLLLFI

Specific function: Mediates zinc uptake. May also transport other divalent cations [H]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily [H]

Homologues:

Organism=Homo sapiens, GI229577418, Length=145, Percent_Identity=34.4827586206897, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI229577422, Length=145, Percent_Identity=34.4827586206897, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1789419, Length=258, Percent_Identity=39.5348837209302, Blast_Score=152, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17507805, Length=295, Percent_Identity=27.7966101694915, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24652846, Length=176, Percent_Identity=31.8181818181818, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 27595; Mature: 27595

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTSTVLFAFGLTLFAGLATGIGGLIAVARKTVTEGFLAGSLGFSVGVMLYVSFVEILPG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AFDELTSVWGEKGGSWAAVIGFFGGIALIAIIDRLVPTAINPHEPSTVGGAVEGFERRNR
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
MMKMGVLTALAIAIHNFPEGFATFLAGLSDPMIAIPVAVAIAIHNIPEGIAVAVPLREAT
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEECHHHC
GSRRKALGWATLSGLAEPAGALIGFLLLMPFIGPEALGLCFAAVAGVMVFISVDELLPTA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISSGKHHTAIYGLIAGMAVMAISLLLFI
HCCCCCHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MDTSTVLFAFGLTLFAGLATGIGGLIAVARKTVTEGFLAGSLGFSVGVMLYVSFVEILPG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AFDELTSVWGEKGGSWAAVIGFFGGIALIAIIDRLVPTAINPHEPSTVGGAVEGFERRNR
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
MMKMGVLTALAIAIHNFPEGFATFLAGLSDPMIAIPVAVAIAIHNIPEGIAVAVPLREAT
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEECHHHC
GSRRKALGWATLSGLAEPAGALIGFLLLMPFIGPEALGLCFAAVAGVMVFISVDELLPTA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISSGKHHTAIYGLIAGMAVMAISLLLFI
HCCCCCHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]