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The map label for this gene is secA2 [H]

Identifier: 62390323

GI number: 62390323

Start: 1518637

End: 1520928

Strand: Direct

Name: secA2 [H]

Synonym: cg1629

Alternate gene names: 62390323

Gene position: 1518637-1520928 (Clockwise)

Preceding gene: 62390318

Following gene: 62390324

Centisome position: 46.26

GC content: 57.94

Gene sequence:

>2292_bases
GTGGCCGGTTTTGATTGGTTTTGGAAGGCCCTTGGCGGCAAATCGGGCAGAAACCAAAAACGTAGCGTGGCAATTGTCAA
TCAGGTAGAAAACCATGCAGCGGAATTAGACGCGCTGGATGATGTTGCATTGGCGCAGCGTGCCAAGGATCTAGCCAGTG
GTGGACGCATTGACAATCATGCGGAATTCCTCGCCATTTTGGGTGTGGCATCGCAGCGGACATTGGGGCTGAAGCCGTAT
CCGGTGCAATCACAGGCGGTGTTGCGTCTCATTGAAGGCGATGTGGTGCACATGGCTACCGGTGAGGGCAAGACTTTGGT
GGGCGCGATGGCGGCCACCGGTCTGGGGTTGATGGGCAAGCGAGTCCATTCGATTACCGTCAATGATTATTTGGCGGTGC
GCGATGCCGAATGGATGCGGCCATTGGTCGAATTTTTCGGTCTGAGCGTGGCGAGCATCAGCGAGAAGATGGATGCAGGG
GAGCGTCGACAAGCATATAAAGCCGCAATTGTCTACGGACCTGTCAATGAAATCGGCTTTGACGTGCTGCGTGATCAGCT
AATTACCCGGCGCGAAGACGCCGTGCAGCATGGCGCCGACGTCGCGATTATCGATGAGGCCGATTCCGTGCTTGTCGACG
AGGCCCTGGTGCCACTCGTCCTCGCCGGCAACCAGCCCGGCCATGCGCCGCGCGGCAAAATCACCGATGTGGTGCGCTCG
TTGAAAGAAAACGACGATTACACCATCGACGATGATCGTCGCAACGTCTTCCTCACCGACAAGGGTGCCGCCAAATTAGA
GCAGCAGCTGGGCATCAGCAGCCTCTACGACGATGAGCACGTCGGCTCGACGCTCGTGCAGGTCAACCTCGCCCTCCACG
CGCAGGCACTGCTCATCCGCGACATCCACTACATCGTCCGCGACAGCAAGGTCTTGCTTATCGACGCCTCCCGCGGCCGT
GTCGCCGACCTGCAGCGCTGGCCCGACGGCCTGCAAGCAGCAGTGGAGGCCAAGGAAGGTCTCGCGGTTTCTGAAGGCGG
CAAGATCCTTGACACCATCACACTTCAGGCGTTGATTGGTCGCTACCCAATGGCATGCGGCATGACAGGTACCGCCGTGG
AGGCAACCGATCAGCTACGCACCTTCTATGACTTGCATGTTTCTGTCATTGAGCGCAATCATCCGCTGAAGCGCTTTGAT
GAAGCTGACCGTATCTACGCCACCATGGCGGAGAAAAACCGCGCCATCATCGATGAAATCGCACTCCTTCACAGCACGGG
GCAGCCAGTCCTGGTGGGTACCCACGATGTGGCAGAGTCGGAAGAACTCGCCACTGCACTGCGTGAACTCAACATCGAAG
TAAGCGTTCTCAACGCCAAGAATGATGCCGAAGAAGCCCAGATCATCGCAGAGGCTGGCGATATTGGACGAGTGACCGTT
TCCACTCAGATGGCCGGCCGCGGTACCGATATTCGCCTCGGTGGCGCCGATGAAGCCGACTACGATGAAGTGGTGAAACT
CGGTGGACTCGCCGTTATCGGCACCGCCCGCCACCGTTCTCAGCGCCTGGACAACCAGCTGCGCGGACGTGCGGGACGAC
AAGGAGATCCAGGCCTGAGCCTTTTCTTTGTCTCCCTCGATGATGATGTGGTGGTCTCAGGCGGGTCAGGGGAGAGCGTG
AGCGCGCAACCCGATGCCACCGGGCTGATTGACTCAGATCGCATCCGCGATTGGGTCGGACACTGCCAGCGCGTCACCGA
AGGACAGCTGCTGGAAATCCACTCCCAGAGCTGGAATTACAACAAGCTCCTTGCCGATCAACGCGTGATCATTGACGAGC
GCCGCGAACGCCTCCTCGACACCGCCTTAGCGTGGGAGGAACTGGCACAGCATGCACCAGCGCGGGCTGCAGAGCTTGAA
GACCTTGATCAGTCCGTGAGGGAACAGGCAGCACGAGACATCATGCTGTACCACCTCGATTACAACTGGTCAGAGCACCT
CGCGTTGATGGATGATGTCCGCGAATCCATTCACCTGCGCGCCATCGCCAGGGAAACCCCCCTTGATGAATACCACCGCA
TCGCTGTGCGTGAATTCAAGGATTTGGCACAACGCGCTGTCGATGATGCGGTGTCCACGTTCAAGTCTGTGACCATCGAT
CACGAGGGTGCCCATTTGGATGATGAGGGCTTGGCGCGTCCATCAGCAACGTGGACCTACATGGTCTCTGACAACCCACT
TGCGGGTAGTGGTAACTCAGTGATCAGTGGCATAGGAAATATCTTTAGATAA

Upstream 100 bases:

>100_bases
TCTTACCCACCAGTGCAATGTAGGTCACGTCGTATCACGTCTGAGGGTGATTGAGTAGGGTTAAACAGATGAATTCATTT
AGCTCACCGGAGGTATAACC

Downstream 100 bases:

>100_bases
CCTGAGAACTATGAAATTCCAGCTCACGGCGTTTTTTCAGGAAATTCTAGGATCTTACGGAGGGTAACTCCGCACTCAAC
ATCTAGACAAAGGCTATGAT

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 763; Mature: 762

Protein sequence:

>763_residues
MAGFDWFWKALGGKSGRNQKRSVAIVNQVENHAAELDALDDVALAQRAKDLASGGRIDNHAEFLAILGVASQRTLGLKPY
PVQSQAVLRLIEGDVVHMATGEGKTLVGAMAATGLGLMGKRVHSITVNDYLAVRDAEWMRPLVEFFGLSVASISEKMDAG
ERRQAYKAAIVYGPVNEIGFDVLRDQLITRREDAVQHGADVAIIDEADSVLVDEALVPLVLAGNQPGHAPRGKITDVVRS
LKENDDYTIDDDRRNVFLTDKGAAKLEQQLGISSLYDDEHVGSTLVQVNLALHAQALLIRDIHYIVRDSKVLLIDASRGR
VADLQRWPDGLQAAVEAKEGLAVSEGGKILDTITLQALIGRYPMACGMTGTAVEATDQLRTFYDLHVSVIERNHPLKRFD
EADRIYATMAEKNRAIIDEIALLHSTGQPVLVGTHDVAESEELATALRELNIEVSVLNAKNDAEEAQIIAEAGDIGRVTV
STQMAGRGTDIRLGGADEADYDEVVKLGGLAVIGTARHRSQRLDNQLRGRAGRQGDPGLSLFFVSLDDDVVVSGGSGESV
SAQPDATGLIDSDRIRDWVGHCQRVTEGQLLEIHSQSWNYNKLLADQRVIIDERRERLLDTALAWEELAQHAPARAAELE
DLDQSVREQAARDIMLYHLDYNWSEHLALMDDVRESIHLRAIARETPLDEYHRIAVREFKDLAQRAVDDAVSTFKSVTID
HEGAHLDDEGLARPSATWTYMVSDNPLAGSGNSVISGIGNIFR

Sequences:

>Translated_763_residues
MAGFDWFWKALGGKSGRNQKRSVAIVNQVENHAAELDALDDVALAQRAKDLASGGRIDNHAEFLAILGVASQRTLGLKPY
PVQSQAVLRLIEGDVVHMATGEGKTLVGAMAATGLGLMGKRVHSITVNDYLAVRDAEWMRPLVEFFGLSVASISEKMDAG
ERRQAYKAAIVYGPVNEIGFDVLRDQLITRREDAVQHGADVAIIDEADSVLVDEALVPLVLAGNQPGHAPRGKITDVVRS
LKENDDYTIDDDRRNVFLTDKGAAKLEQQLGISSLYDDEHVGSTLVQVNLALHAQALLIRDIHYIVRDSKVLLIDASRGR
VADLQRWPDGLQAAVEAKEGLAVSEGGKILDTITLQALIGRYPMACGMTGTAVEATDQLRTFYDLHVSVIERNHPLKRFD
EADRIYATMAEKNRAIIDEIALLHSTGQPVLVGTHDVAESEELATALRELNIEVSVLNAKNDAEEAQIIAEAGDIGRVTV
STQMAGRGTDIRLGGADEADYDEVVKLGGLAVIGTARHRSQRLDNQLRGRAGRQGDPGLSLFFVSLDDDVVVSGGSGESV
SAQPDATGLIDSDRIRDWVGHCQRVTEGQLLEIHSQSWNYNKLLADQRVIIDERRERLLDTALAWEELAQHAPARAAELE
DLDQSVREQAARDIMLYHLDYNWSEHLALMDDVRESIHLRAIARETPLDEYHRIAVREFKDLAQRAVDDAVSTFKSVTID
HEGAHLDDEGLARPSATWTYMVSDNPLAGSGNSVISGIGNIFR
>Mature_762_residues
AGFDWFWKALGGKSGRNQKRSVAIVNQVENHAAELDALDDVALAQRAKDLASGGRIDNHAEFLAILGVASQRTLGLKPYP
VQSQAVLRLIEGDVVHMATGEGKTLVGAMAATGLGLMGKRVHSITVNDYLAVRDAEWMRPLVEFFGLSVASISEKMDAGE
RRQAYKAAIVYGPVNEIGFDVLRDQLITRREDAVQHGADVAIIDEADSVLVDEALVPLVLAGNQPGHAPRGKITDVVRSL
KENDDYTIDDDRRNVFLTDKGAAKLEQQLGISSLYDDEHVGSTLVQVNLALHAQALLIRDIHYIVRDSKVLLIDASRGRV
ADLQRWPDGLQAAVEAKEGLAVSEGGKILDTITLQALIGRYPMACGMTGTAVEATDQLRTFYDLHVSVIERNHPLKRFDE
ADRIYATMAEKNRAIIDEIALLHSTGQPVLVGTHDVAESEELATALRELNIEVSVLNAKNDAEEAQIIAEAGDIGRVTVS
TQMAGRGTDIRLGGADEADYDEVVKLGGLAVIGTARHRSQRLDNQLRGRAGRQGDPGLSLFFVSLDDDVVVSGGSGESVS
AQPDATGLIDSDRIRDWVGHCQRVTEGQLLEIHSQSWNYNKLLADQRVIIDERRERLLDTALAWEELAQHAPARAAELED
LDQSVREQAARDIMLYHLDYNWSEHLALMDDVRESIHLRAIARETPLDEYHRIAVREFKDLAQRAVDDAVSTFKSVTIDH
EGAHLDDEGLARPSATWTYMVSDNPLAGSGNSVISGIGNIFR

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family [H]

Homologues:

Organism=Escherichia coli, GI1786287, Length=665, Percent_Identity=37.7443609022556, Blast_Score=381, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116 [H]

Pfam domain/function: PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]

EC number: NA

Molecular weight: Translated: 83502; Mature: 83371

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS01312 SECA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGFDWFWKALGGKSGRNQKRSVAIVNQVENHAAELDALDDVALAQRAKDLASGGRIDNH
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AEFLAILGVASQRTLGLKPYPVQSQAVLRLIEGDVVHMATGEGKTLVGAMAATGLGLMGK
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCHHHCC
RVHSITVNDYLAVRDAEWMRPLVEFFGLSVASISEKMDAGERRQAYKAAIVYGPVNEIGF
CEEEEEECCEEEECCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHEEEEEECCHHHHHH
DVLRDQLITRREDAVQHGADVAIIDEADSVLVDEALVPLVLAGNQPGHAPRGKITDVVRS
HHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHH
LKENDDYTIDDDRRNVFLTDKGAAKLEQQLGISSLYDDEHVGSTLVQVNLALHAQALLIR
HHCCCCCEECCCCCEEEEECCCHHHHHHHCCCHHHCCCHHHCCEEEEEEHHHHHHHHHHH
DIHYIVRDSKVLLIDASRGRVADLQRWPDGLQAAVEAKEGLAVSEGGKILDTITLQALIG
HHHHHHCCCEEEEEECCCCCHHHHHHCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHC
RYPMACGMTGTAVEATDQLRTFYDLHVSVIERNHPLKRFDEADRIYATMAEKNRAIIDEI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHCCHHHHHHH
ALLHSTGQPVLVGTHDVAESEELATALRELNIEVSVLNAKNDAEEAQIIAEAGDIGRVTV
HHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCCCEEEE
STQMAGRGTDIRLGGADEADYDEVVKLGGLAVIGTARHRSQRLDNQLRGRAGRQGDPGLS
EEEECCCCCEEEECCCCCCCHHHHHHHCCEEEEECHHHHHHHHHHHHHCCCCCCCCCCCE
LFFVSLDDDVVVSGGSGESVSAQPDATGLIDSDRIRDWVGHCQRVTEGQLLEIHSQSWNY
EEEEEECCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCC
NKLLADQRVIIDERRERLLDTALAWEELAQHAPARAAELEDLDQSVREQAARDIMLYHLD
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCEEEEEEC
YNWSEHLALMDDVRESIHLRAIARETPLDEYHRIAVREFKDLAQRAVDDAVSTFKSVTID
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
HEGAHLDDEGLARPSATWTYMVSDNPLAGSGNSVISGIGNIFR
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
AGFDWFWKALGGKSGRNQKRSVAIVNQVENHAAELDALDDVALAQRAKDLASGGRIDNH
CCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AEFLAILGVASQRTLGLKPYPVQSQAVLRLIEGDVVHMATGEGKTLVGAMAATGLGLMGK
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCHHHCC
RVHSITVNDYLAVRDAEWMRPLVEFFGLSVASISEKMDAGERRQAYKAAIVYGPVNEIGF
CEEEEEECCEEEECCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHEEEEEECCHHHHHH
DVLRDQLITRREDAVQHGADVAIIDEADSVLVDEALVPLVLAGNQPGHAPRGKITDVVRS
HHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHH
LKENDDYTIDDDRRNVFLTDKGAAKLEQQLGISSLYDDEHVGSTLVQVNLALHAQALLIR
HHCCCCCEECCCCCEEEEECCCHHHHHHHCCCHHHCCCHHHCCEEEEEEHHHHHHHHHHH
DIHYIVRDSKVLLIDASRGRVADLQRWPDGLQAAVEAKEGLAVSEGGKILDTITLQALIG
HHHHHHCCCEEEEEECCCCCHHHHHHCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHC
RYPMACGMTGTAVEATDQLRTFYDLHVSVIERNHPLKRFDEADRIYATMAEKNRAIIDEI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHCCHHHHHHH
ALLHSTGQPVLVGTHDVAESEELATALRELNIEVSVLNAKNDAEEAQIIAEAGDIGRVTV
HHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCCCEEEE
STQMAGRGTDIRLGGADEADYDEVVKLGGLAVIGTARHRSQRLDNQLRGRAGRQGDPGLS
EEEECCCCCEEEECCCCCCCHHHHHHHCCEEEEECHHHHHHHHHHHHHCCCCCCCCCCCE
LFFVSLDDDVVVSGGSGESVSAQPDATGLIDSDRIRDWVGHCQRVTEGQLLEIHSQSWNY
EEEEEECCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCC
NKLLADQRVIIDERRERLLDTALAWEELAQHAPARAAELEDLDQSVREQAARDIMLYHLD
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCEEEEEEC
YNWSEHLALMDDVRESIHLRAIARETPLDEYHRIAVREFKDLAQRAVDDAVSTFKSVTID
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
HEGAHLDDEGLARPSATWTYMVSDNPLAGSGNSVISGIGNIFR
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA