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The map label for this gene is engA [H]

Identifier: 62390312

GI number: 62390312

Start: 1506412

End: 1508043

Strand: Direct

Name: engA [H]

Synonym: cg1617

Alternate gene names: 62390312

Gene position: 1506412-1508043 (Clockwise)

Preceding gene: 62390311

Following gene: 62390316

Centisome position: 45.89

GC content: 54.96

Gene sequence:

>1632_bases
GTGACTGATAAACACACCATGCCTGGTGAAGAGGACGACACCGTATTCGTCTACCACACCCACAAAGGCGAAATGGACGT
CGAAGGTGCGTTTGCTGACGAAGAAGAACTAGCACCACACGGCGGTTGGGCTTCCGCAGATTTCGACCCAGCAGAATTCG
GCTACGAAGACTCTGACGATGACTTCGATGCAGAGGACTTTGACGAAACAGAGTTCTCCAACCCTGATTTCGGCGAAGAC
TACTCTGATGAAGACTGGGAAGAAATCGAGACCGCATTCGGATTCGACCCAAGCCACCTTGAAGAAGCTCTCTGCACGGT
CGCTATCGTCGGACGCCCAAATGTTGGTAAATCAACCTTGGTGAACCGCTTTATTGGACGTCGAGAAGCAGTCGTGGAAG
ATTTCCCCGGCGTAACCCGTGACCGCATCTCCTACATCTCTGACTGGGGTGGACACCGTTTCTGGGTTCAGGACACAGGC
GGATGGGATCCTAACGTCAAGGGCATCCACGCATCGATCGCACAGCAAGCAGAAGTTGCTATGAGCACTGCCGATGTCAT
CGTATTCGTCGTGGACACCAAGGTGGGCATCACCGAAACTGACTCAGTGATGGCAGCAAAACTGTTGCGCTCGGAAGTGC
CAGTGATCTTGGTTGCGAACAAATTCGACTCCGACAGCCAGTGGGCTGACATGGCTGAGTTCTACAGCCTCGGCCTTGGC
GATCCATACCCAGTTTCAGCCCAGCATGGACGTGGTGGCGCTGACGTTTTGGACAAAGTCCTTGAACTCTTCCCAGAAGA
GCCTCGCTCCAAGTCCATCGTGGAAGGCCCTCGTCGTGTCGCCCTTGTGGGTAAGCCAAACGTGGGTAAGTCTTCACTGC
TCAACAAGTTTGCTGGCGAGACCCGCTCTGTCGTGGACAATGTTGCAGGAACCACCGTTGACCCCGTTGACTCCCTGATT
CAGCTGGATCAAAAACTGTGGAAATTCGTGGATACTGCTGGTCTTCGCAAAAAGGTCAAGACTGCATCTGGCCACGAGTA
CTACGCATCACTGCGTACCCACGGTGCCATCGATGCAGCTGAGCTGTGTGTTTTGCTTATCGATTCCTCCGAACCCATCA
CCGAGCAGGATCAGCGCGTGCTCGCAATGATCACCGATGCCGGTAAGGCACTGGTTATTGCGTTCAACAAGTGGGATCTC
ATGGATGAAGATCGCCGCATCGATTTGGATCGCGAACTTGATCTCCAGTTGGCACACGTGCCTTGGGCAAAGCGCATCAA
CATCTCCGCCAAAACCGGTCGTGCACTGCAGCGCCTCGAGCCAGCAATGTTGGAAGCGCTCGACAACTGGGATCGCCGTA
TCTCCACTGGTCAGCTGAACACCTGGCTGCGTGAAGCAATTGCTGCGAACCCACCACCAATGCGTGGCGGACGTTTGCCT
CGAGTGCTGTTTGCCACCCAGGCATCTACTCAGCCACCAGTGATCGTACTGTTCACCACCGGCTTCCTCGAAGCAGGTTA
CCGACGATACCTGGAGCGCAAGTTCCGTGAACGTTTCGGCTTTGAAGGCACTCCAGTGCGAATCGCTGTGCGTGTTCGCG
AGCGCCGCGGCAAGGGCGGAAACAAGCAGTAA

Upstream 100 bases:

>100_bases
CAGATGATGCACACATCGTGGACACCTCTGATATGACCATGGATCAAGTACTTGATCACCTCATCCACCTAGTGGAAGCC
TCCGCTGAAAGGAGCAACCA

Downstream 100 bases:

>100_bases
AGCTTGATTTTCCCTAAAAGCACTTATCCCCACGTTGAAAATGACGTGGGGATAAGTGCTTTTTGTTCAAAAGAGCGGAT
TTCTAATCGTTTACAGTAAT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 543; Mature: 542

Protein sequence:

>543_residues
MTDKHTMPGEEDDTVFVYHTHKGEMDVEGAFADEEELAPHGGWASADFDPAEFGYEDSDDDFDAEDFDETEFSNPDFGED
YSDEDWEEIETAFGFDPSHLEEALCTVAIVGRPNVGKSTLVNRFIGRREAVVEDFPGVTRDRISYISDWGGHRFWVQDTG
GWDPNVKGIHASIAQQAEVAMSTADVIVFVVDTKVGITETDSVMAAKLLRSEVPVILVANKFDSDSQWADMAEFYSLGLG
DPYPVSAQHGRGGADVLDKVLELFPEEPRSKSIVEGPRRVALVGKPNVGKSSLLNKFAGETRSVVDNVAGTTVDPVDSLI
QLDQKLWKFVDTAGLRKKVKTASGHEYYASLRTHGAIDAAELCVLLIDSSEPITEQDQRVLAMITDAGKALVIAFNKWDL
MDEDRRIDLDRELDLQLAHVPWAKRINISAKTGRALQRLEPAMLEALDNWDRRISTGQLNTWLREAIAANPPPMRGGRLP
RVLFATQASTQPPVIVLFTTGFLEAGYRRYLERKFRERFGFEGTPVRIAVRVRERRGKGGNKQ

Sequences:

>Translated_543_residues
MTDKHTMPGEEDDTVFVYHTHKGEMDVEGAFADEEELAPHGGWASADFDPAEFGYEDSDDDFDAEDFDETEFSNPDFGED
YSDEDWEEIETAFGFDPSHLEEALCTVAIVGRPNVGKSTLVNRFIGRREAVVEDFPGVTRDRISYISDWGGHRFWVQDTG
GWDPNVKGIHASIAQQAEVAMSTADVIVFVVDTKVGITETDSVMAAKLLRSEVPVILVANKFDSDSQWADMAEFYSLGLG
DPYPVSAQHGRGGADVLDKVLELFPEEPRSKSIVEGPRRVALVGKPNVGKSSLLNKFAGETRSVVDNVAGTTVDPVDSLI
QLDQKLWKFVDTAGLRKKVKTASGHEYYASLRTHGAIDAAELCVLLIDSSEPITEQDQRVLAMITDAGKALVIAFNKWDL
MDEDRRIDLDRELDLQLAHVPWAKRINISAKTGRALQRLEPAMLEALDNWDRRISTGQLNTWLREAIAANPPPMRGGRLP
RVLFATQASTQPPVIVLFTTGFLEAGYRRYLERKFRERFGFEGTPVRIAVRVRERRGKGGNKQ
>Mature_542_residues
TDKHTMPGEEDDTVFVYHTHKGEMDVEGAFADEEELAPHGGWASADFDPAEFGYEDSDDDFDAEDFDETEFSNPDFGEDY
SDEDWEEIETAFGFDPSHLEEALCTVAIVGRPNVGKSTLVNRFIGRREAVVEDFPGVTRDRISYISDWGGHRFWVQDTGG
WDPNVKGIHASIAQQAEVAMSTADVIVFVVDTKVGITETDSVMAAKLLRSEVPVILVANKFDSDSQWADMAEFYSLGLGD
PYPVSAQHGRGGADVLDKVLELFPEEPRSKSIVEGPRRVALVGKPNVGKSSLLNKFAGETRSVVDNVAGTTVDPVDSLIQ
LDQKLWKFVDTAGLRKKVKTASGHEYYASLRTHGAIDAAELCVLLIDSSEPITEQDQRVLAMITDAGKALVIAFNKWDLM
DEDRRIDLDRELDLQLAHVPWAKRINISAKTGRALQRLEPAMLEALDNWDRRISTGQLNTWLREAIAANPPPMRGGRLPR
VLFATQASTQPPVIVLFTTGFLEAGYRRYLERKFRERFGFEGTPVRIAVRVRERRGKGGNKQ

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=460, Percent_Identity=35.6521739130435, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI1788919, Length=174, Percent_Identity=30.4597701149425, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=180, Percent_Identity=27.2222222222222, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 60453; Mature: 60322

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKHTMPGEEDDTVFVYHTHKGEMDVEGAFADEEELAPHGGWASADFDPAEFGYEDSDD
CCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHCCCCCCCC
DFDAEDFDETEFSNPDFGEDYSDEDWEEIETAFGFDPSHLEEALCTVAIVGRPNVGKSTL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHEEEEECCCCCCHHHH
VNRFIGRREAVVEDFPGVTRDRISYISDWGGHRFWVQDTGGWDPNVKGIHASIAQQAEVA
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHH
MSTADVIVFVVDTKVGITETDSVMAAKLLRSEVPVILVANKFDSDSQWADMAEFYSLGLG
HCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCC
DPYPVSAQHGRGGADVLDKVLELFPEEPRSKSIVEGPRRVALVGKPNVGKSSLLNKFAGE
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCCCEEEEEECCCCCHHHHHHHHHCH
TRSVVDNVAGTTVDPVDSLIQLDQKLWKFVDTAGLRKKVKTASGHEYYASLRTHGAIDAA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHH
ELCVLLIDSSEPITEQDQRVLAMITDAGKALVIAFNKWDLMDEDRRIDLDRELDLQLAHV
HEEEEEECCCCCCCHHHHEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEECC
PWAKRINISAKTGRALQRLEPAMLEALDNWDRRISTGQLNTWLREAIAANPPPMRGGRLP
CCCCEEEEEHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCC
RVLFATQASTQPPVIVLFTTGFLEAGYRRYLERKFRERFGFEGTPVRIAVRVRERRGKGG
EEEEEECCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHCCCCC
NKQ
CCC
>Mature Secondary Structure 
TDKHTMPGEEDDTVFVYHTHKGEMDVEGAFADEEELAPHGGWASADFDPAEFGYEDSDD
CCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHCCCCCCCC
DFDAEDFDETEFSNPDFGEDYSDEDWEEIETAFGFDPSHLEEALCTVAIVGRPNVGKSTL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHEEEEECCCCCCHHHH
VNRFIGRREAVVEDFPGVTRDRISYISDWGGHRFWVQDTGGWDPNVKGIHASIAQQAEVA
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHH
MSTADVIVFVVDTKVGITETDSVMAAKLLRSEVPVILVANKFDSDSQWADMAEFYSLGLG
HCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCC
DPYPVSAQHGRGGADVLDKVLELFPEEPRSKSIVEGPRRVALVGKPNVGKSSLLNKFAGE
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCCCEEEEEECCCCCHHHHHHHHHCH
TRSVVDNVAGTTVDPVDSLIQLDQKLWKFVDTAGLRKKVKTASGHEYYASLRTHGAIDAA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHH
ELCVLLIDSSEPITEQDQRVLAMITDAGKALVIAFNKWDLMDEDRRIDLDRELDLQLAHV
HEEEEEECCCCCCCHHHHEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEECC
PWAKRINISAKTGRALQRLEPAMLEALDNWDRRISTGQLNTWLREAIAANPPPMRGGRLP
CCCCEEEEEHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCC
RVLFATQASTQPPVIVLFTTGFLEAGYRRYLERKFRERFGFEGTPVRIAVRVRERRGKGG
EEEEEECCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHCCCCC
NKQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]