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The map label for this gene is nudF [H]

Identifier: 62390302

GI number: 62390302

Start: 1496654

End: 1497331

Strand: Direct

Name: nudF [H]

Synonym: cg1607

Alternate gene names: 62390302

Gene position: 1496654-1497331 (Clockwise)

Preceding gene: 62390301

Following gene: 62390303

Centisome position: 45.59

GC content: 55.16

Gene sequence:

>678_bases
GTGATCATGGTTTCGAAGATGCACATTCCCGGTACCCATGAGTTCACGGTGACAGATACTGAACTGTTGTTAGAGTCCCC
AATTTTGGGCGTTCGTCGAGATTCATTGATCATGCCGGGTGGTTCCACTGCCCGCCGTGAAGTGGTTGAACACTTTGGGG
CGGTCGCAGTGGTTGCCTTTGATGGTGAAAACATTGCGATGGTCAAGCAGTACCGTCGCAGCGTGGGGGATTCCTTGTGG
GAGCTGCCTGCAGGTTTGTTGGATATTGCTGATGAGGATGAACTCACGGGCGCGCAGCGCGAGCTCATGGAGGAGGCTGG
TTTGGAGGCCAGTGAGTGGTCCGTGCTCACTGATTTGATTACCTCGCCTGGTTTCTGCGATGAAGCGGTGCGTGTCTTTC
TAGCCCGAGGCCTCACAAAGGTTGAGCGCCCGAAGGTTATGGGCGATGAAGAAGCGGACATGATTAACCAGTGGGTTCCG
CTACATGAGGCAGTGGGAATGGTGTTTAGTGGCCAGTTGGTTAACTCCATTGCCATTGCGGGTGTCATGGCTGCTGATGC
TGTGATTGCGGGTCGTGCGTCTGCGCGTGCCGTCACCGCGCCGTTTACCTATCGCCCTACGGCGTTGGCGCAGCGTCGAA
AAGCGCACGGCATTGTTCCTGACATGAAAAAACTATGA

Upstream 100 bases:

>100_bases
GCACCCTGAGTACAAATCTCGTCCAACCCATGCTCATCCACTGTTTTACGGCCTGGTGAAGACCGCTTTGGAGCTGCGTG
TCCACCCTTAGATCTACAAT

Downstream 100 bases:

>100_bases
AGGCTCGCGTTTTAGCGAAAACATGGCTGACACATTTGGCCGTGGAGCGTGGCTTGTCGGCAAATACGCTGAGTAATTAT
CGGCGCGATGTGGAACGCTA

Product: NTP pyrophosphohydrolase including oxidative damage repair enzyme

Products: NA

Alternate protein names: ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ASPPase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MIMVSKMHIPGTHEFTVTDTELLLESPILGVRRDSLIMPGGSTARREVVEHFGAVAVVAFDGENIAMVKQYRRSVGDSLW
ELPAGLLDIADEDELTGAQRELMEEAGLEASEWSVLTDLITSPGFCDEAVRVFLARGLTKVERPKVMGDEEADMINQWVP
LHEAVGMVFSGQLVNSIAIAGVMAADAVIAGRASARAVTAPFTYRPTALAQRRKAHGIVPDMKKL

Sequences:

>Translated_225_residues
MIMVSKMHIPGTHEFTVTDTELLLESPILGVRRDSLIMPGGSTARREVVEHFGAVAVVAFDGENIAMVKQYRRSVGDSLW
ELPAGLLDIADEDELTGAQRELMEEAGLEASEWSVLTDLITSPGFCDEAVRVFLARGLTKVERPKVMGDEEADMINQWVP
LHEAVGMVFSGQLVNSIAIAGVMAADAVIAGRASARAVTAPFTYRPTALAQRRKAHGIVPDMKKL
>Mature_225_residues
MIMVSKMHIPGTHEFTVTDTELLLESPILGVRRDSLIMPGGSTARREVVEHFGAVAVVAFDGENIAMVKQYRRSVGDSLW
ELPAGLLDIADEDELTGAQRELMEEAGLEASEWSVLTDLITSPGFCDEAVRVFLARGLTKVERPKVMGDEEADMINQWVP
LHEAVGMVFSGQLVNSIAIAGVMAADAVIAGRASARAVTAPFTYRPTALAQRRKAHGIVPDMKKL

Specific function: Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004385
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =3.6.1.13 [H]

Molecular weight: Translated: 24414; Mature: 24414

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMVSKMHIPGTHEFTVTDTELLLESPILGVRRDSLIMPGGSTARREVVEHFGAVAVVAF
CEEEEEECCCCCCEEEECHHHHHHHCCCCCCCCCCEECCCCCHHHHHHHHHCCCEEEEEE
DGENIAMVKQYRRSVGDSLWELPAGLLDIADEDELTGAQRELMEEAGLEASEWSVLTDLI
CCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
TSPGFCDEAVRVFLARGLTKVERPKVMGDEEADMINQWVPLHEAVGMVFSGQLVNSIAIA
CCCCCHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GVMAADAVIAGRASARAVTAPFTYRPTALAQRRKAHGIVPDMKKL
HHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCHHCC
>Mature Secondary Structure
MIMVSKMHIPGTHEFTVTDTELLLESPILGVRRDSLIMPGGSTARREVVEHFGAVAVVAF
CEEEEEECCCCCCEEEECHHHHHHHCCCCCCCCCCEECCCCCHHHHHHHHHCCCEEEEEE
DGENIAMVKQYRRSVGDSLWELPAGLLDIADEDELTGAQRELMEEAGLEASEWSVLTDLI
CCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
TSPGFCDEAVRVFLARGLTKVERPKVMGDEEADMINQWVPLHEAVGMVFSGQLVNSIAIA
CCCCCHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GVMAADAVIAGRASARAVTAPFTYRPTALAQRRKAHGIVPDMKKL
HHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10542272 [H]