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The map label for this gene is accDA [H]

Identifier: 62389721

GI number: 62389721

Start: 881110

End: 882564

Strand: Reverse

Name: accDA [H]

Synonym: cg0951

Alternate gene names: 62389721

Gene position: 882564-881110 (Counterclockwise)

Preceding gene: 62389725

Following gene: 62389718

Centisome position: 26.89

GC content: 59.04

Gene sequence:

>1455_bases
ATGGTGTGGGGCATGGAACACACTTCAGCATTGACGCTCATAGACTCGGTTTTGGACCCTGACAGCTTCATTTCTTGGAA
TGAAACTCCCCAATATGACAACCTCAATCAAGGCTATGCAGAGACCTTGGAGCGGGCTCGAAGCAAGGCCAAATGCGATG
AATCGGTAATTACTGGAGAAGGCACCGTGGAGGGCATTCCGGTAGCCGTTATTTTGTCCGATTTTTCCTTCCTCGGCGGT
TCTTTGGGCACGGTCGCGTCGGTGCGCATCATGAAGGCGATTCACCGCGCCACAGAGCTGAAACTCCCACTGCTGGTCTC
CCCTGCTTCCGGTGGTGCGCGCATGCAGGAAGACAATCGAGCTTTTGTCATGATGGTGTCCATAACCGCGGCTGTGCAGC
GTCACCGCGAGGCGCATTTGCCGTTCCTGGTGTATTTGCGCAATCCCACGATGGGTGGCGCCATGGCCTCGTGGGGTTCA
TCTGGGCATCTCACTTTTGCGGAACCCGGCGCGCAGATAGGTTTCCTGGGTCCTCGCGTGGTGGAGTTAACCACTGGGCA
TGCGCTTCCAGACGGTGTGCAGCAGGCGGAGAATTTGGTGAAAACTGGTGTGATTGATGGAATTGTGTCGCCACTCCAAT
TGCGTGCAGCGGTGGCAAAAACCCTCAAGGTTATTCAGCCGGTAGAGGCAACGGATCGTTTTTCTCCAACAACTCCTGGC
GTGGCACTTCCGGTGATGGAGGCGATTGCGCGTTCTCGTGACCCGCAGAGGCCTGGAATCGGGGAGATTATGGAAACGTT
GGGGGCAGACGTCGTCAAGCTTTCTGGTGCGCGTGCTGGCGCATTGAGCCCGGCTGTGCGCGTTGCCCTGGCGCGCATCG
GGGGCCGGCCCGTGGTGCTGATTGGGCAGGATCGCCGCTTCACGCTTGGGCCGCAGGAGCTGCGTTTTGCGCGTCGTGGC
ATTTCGCTGGCGCGCGAGCTAAACCTGCCGATCGTGTCCATCATCGACACCTCCGGCGCCGAATTGTCGCAGGCGGCTGA
GGAGCTCGGCATCGCAAGCTCGATTGCGCGCACCTTGTCCAAGCTTATCGACGCTCCCCTCCCCACCGTTTCGGTCATTA
TTGGTCAGGGCGTTGGCGGTGGCGCGCTGGCCATGCTGCCCGCCGATCTGGTCTACGCGGCCGAAAACGCGTGGCTGTCC
GCATTGCCACCAGAGGGCGCCTCGGCCATCCTCTTCCGCGACACCAACCACGCCGCGGAAATCATAGAGCGACAAGGCGT
GCAGGCGCACGCACTTTTAAGCCAAGGGCTTATCGACGGGATCGTCGCCGAAACCGAGCACTTTGTTGAAGAAATTCTCG
GCACAATCAGCAACGCCCTCTCCGAATTGGATAACAATCCGGAGAGGGCGGGACGCGACAGTCGCTTCACACGATTTGAG
CGTTTAGCGCAGTAA

Upstream 100 bases:

>100_bases
CTAAATTGGGCTTAGATCTTCCGCCTCTAAATAGGTATGCAGAGACATTCGAATTAATTAACAAAGCCATTTTTCGGCCG
TGGAGAAGCGTTTTCCGACT

Downstream 100 bases:

>100_bases
AGAAAATTATGCGCTGATCAAATCGATGATGAACACCAGGGTACGGCCAGACAGTGGGTGGCCGGAACCCTCAGGGCCGT
AAGCAGCCTCTGGCGGAATG

Product: acetyl-coenzyme A carboxylase carboxyl transferase

Products: NA

Alternate protein names: ACCase beta chain [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MVWGMEHTSALTLIDSVLDPDSFISWNETPQYDNLNQGYAETLERARSKAKCDESVITGEGTVEGIPVAVILSDFSFLGG
SLGTVASVRIMKAIHRATELKLPLLVSPASGGARMQEDNRAFVMMVSITAAVQRHREAHLPFLVYLRNPTMGGAMASWGS
SGHLTFAEPGAQIGFLGPRVVELTTGHALPDGVQQAENLVKTGVIDGIVSPLQLRAAVAKTLKVIQPVEATDRFSPTTPG
VALPVMEAIARSRDPQRPGIGEIMETLGADVVKLSGARAGALSPAVRVALARIGGRPVVLIGQDRRFTLGPQELRFARRG
ISLARELNLPIVSIIDTSGAELSQAAEELGIASSIARTLSKLIDAPLPTVSVIIGQGVGGGALAMLPADLVYAAENAWLS
ALPPEGASAILFRDTNHAAEIIERQGVQAHALLSQGLIDGIVAETEHFVEEILGTISNALSELDNNPERAGRDSRFTRFE
RLAQ

Sequences:

>Translated_484_residues
MVWGMEHTSALTLIDSVLDPDSFISWNETPQYDNLNQGYAETLERARSKAKCDESVITGEGTVEGIPVAVILSDFSFLGG
SLGTVASVRIMKAIHRATELKLPLLVSPASGGARMQEDNRAFVMMVSITAAVQRHREAHLPFLVYLRNPTMGGAMASWGS
SGHLTFAEPGAQIGFLGPRVVELTTGHALPDGVQQAENLVKTGVIDGIVSPLQLRAAVAKTLKVIQPVEATDRFSPTTPG
VALPVMEAIARSRDPQRPGIGEIMETLGADVVKLSGARAGALSPAVRVALARIGGRPVVLIGQDRRFTLGPQELRFARRG
ISLARELNLPIVSIIDTSGAELSQAAEELGIASSIARTLSKLIDAPLPTVSVIIGQGVGGGALAMLPADLVYAAENAWLS
ALPPEGASAILFRDTNHAAEIIERQGVQAHALLSQGLIDGIVAETEHFVEEILGTISNALSELDNNPERAGRDSRFTRFE
RLAQ
>Mature_484_residues
MVWGMEHTSALTLIDSVLDPDSFISWNETPQYDNLNQGYAETLERARSKAKCDESVITGEGTVEGIPVAVILSDFSFLGG
SLGTVASVRIMKAIHRATELKLPLLVSPASGGARMQEDNRAFVMMVSITAAVQRHREAHLPFLVYLRNPTMGGAMASWGS
SGHLTFAEPGAQIGFLGPRVVELTTGHALPDGVQQAENLVKTGVIDGIVSPLQLRAAVAKTLKVIQPVEATDRFSPTTPG
VALPVMEAIARSRDPQRPGIGEIMETLGADVVKLSGARAGALSPAVRVALARIGGRPVVLIGQDRRFTLGPQELRFARRG
ISLARELNLPIVSIIDTSGAELSQAAEELGIASSIARTLSKLIDAPLPTVSVIIGQGVGGGALAMLPADLVYAAENAWLS
ALPPEGASAILFRDTNHAAEIIERQGVQAHALLSQGLIDGIVAETEHFVEEILGTISNALSELDNNPERAGRDSRFTRFE
RLAQ

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA [H]

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Escherichia coli, GI1788655, Length=236, Percent_Identity=36.0169491525424, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1786382, Length=204, Percent_Identity=33.8235294117647, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 51349; Mature: 51349

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWGMEHTSALTLIDSVLDPDSFISWNETPQYDNLNQGYAETLERARSKAKCDESVITGE
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEECCC
GTVEGIPVAVILSDFSFLGGSLGTVASVRIMKAIHRATELKLPLLVSPASGGARMQEDNR
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCC
AFVMMVSITAAVQRHREAHLPFLVYLRNPTMGGAMASWGSSGHLTFAEPGAQIGFLGPRV
EEEEEHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHCCCCCCCEEECCCCCCEECCCCEE
VELTTGHALPDGVQQAENLVKTGVIDGIVSPLQLRAAVAKTLKVIQPVEATDRFSPTTPG
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCC
VALPVMEAIARSRDPQRPGIGEIMETLGADVVKLSGARAGALSPAVRVALARIGGRPVVL
HHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHCCCEEEE
IGQDRRFTLGPQELRFARRGISLARELNLPIVSIIDTSGAELSQAAEELGIASSIARTLS
EECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
KLIDAPLPTVSVIIGQGVGGGALAMLPADLVYAAENAWLSALPPEGASAILFRDTNHAAE
HHHCCCCCCEEHEEECCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCEEEEECCCHHHH
IIERQGVQAHALLSQGLIDGIVAETEHFVEEILGTISNALSELDNNPERAGRDSRFTRFE
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHH
RLAQ
HHCC
>Mature Secondary Structure
MVWGMEHTSALTLIDSVLDPDSFISWNETPQYDNLNQGYAETLERARSKAKCDESVITGE
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEECCC
GTVEGIPVAVILSDFSFLGGSLGTVASVRIMKAIHRATELKLPLLVSPASGGARMQEDNR
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCC
AFVMMVSITAAVQRHREAHLPFLVYLRNPTMGGAMASWGSSGHLTFAEPGAQIGFLGPRV
EEEEEHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHCCCCCCCEEECCCCCCEECCCCEE
VELTTGHALPDGVQQAENLVKTGVIDGIVSPLQLRAAVAKTLKVIQPVEATDRFSPTTPG
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCC
VALPVMEAIARSRDPQRPGIGEIMETLGADVVKLSGARAGALSPAVRVALARIGGRPVVL
HHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHCCCEEEE
IGQDRRFTLGPQELRFARRGISLARELNLPIVSIIDTSGAELSQAAEELGIASSIARTLS
EECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
KLIDAPLPTVSVIIGQGVGGGALAMLPADLVYAAENAWLSALPPEGASAILFRDTNHAAE
HHHCCCCCCEEHEEECCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCEEEEECCCHHHH
IIERQGVQAHALLSQGLIDGIVAETEHFVEEILGTISNALSELDNNPERAGRDSRFTRFE
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHH
RLAQ
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]