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The map label for this gene is serC [H]

Identifier: 62389718

GI number: 62389718

Start: 877453

End: 878583

Strand: Reverse

Name: serC [H]

Synonym: cg0948

Alternate gene names: 62389718

Gene position: 878583-877453 (Counterclockwise)

Preceding gene: 62389721

Following gene: 62389717

Centisome position: 26.76

GC content: 57.29

Gene sequence:

>1131_bases
ATGACCGACTTCCCCACCCTGCCCTCTGAGTTCATCCCTGGCGACGGCCGTTTCGGCTGCGGACCTTCCAAGGTTCGACC
AGAACAGATTCAGGCTATTGTCGACGGATCCGCATCCGTCATCGGTACCTCACACCGTCAGCCGGCAGTAAAAAACGTCG
TGGGTTCAATCCGCGAGGGACTCTCCGACCTCTTCTCCCTTCCAGAAGGCTACGAGATCATCCTTTCCCTAGGTGGTGCG
ACCGCATTCTGGGATGCAGCAACCTTCGGACTCATTGAAAAGAAGTCCGGTCACCTTTCTTTCGGTGAGTTCTCCTCCAA
GTTCGCAAAGGCTTCTAAGCTTGCTCCTTGGCTCGACGAGCCAGAGATCGTCACCGCAGAAACCGGTGACTCTCCGGCCC
CACAGGCATTCGAAGGCGCCGATGTTATTGCATGGGCACACAACGAAACCTCCACTGGCGCCATGGTTCCAGTTCTTCGC
CCCGAAGGCTCTGAAGGCTCCCTGGTTGCCATTGACGCAACCTCCGGCGCTGGTGGACTGCCAGTAGACATCAAGAACTC
CGATGTTTACTACTTCTCCCCACAGAAGTGCTTCGCATCCGACGGTGGCCTGTGGCTTGCAGCGATGAGCCCAGCAGCTC
TCGAGCGCATCGAGAAGATCAACGCTTCCGATCGCTTCATCCCTGAGTTCCTCAACCTGCAGACCGCAGTGGATAACTCC
CTGAAGAACCAGACCTACAACACCCCAGCTGTTGCTACCTTGCTGATGCTGGACAACCAGGTCAAGTGGATGAACTCCAA
CGGCGGCCTGGATGGAATGGTTGCTCGCACCACAGCAAGCTCCTCCGCCCTGTACAACTGGGCTGAGGCTCGCGAGGAGG
CATCCCCATACGTGGCAGATGCAGCTAAGCGCTCCCTCGTTGTCGGCACCATCGACTTCGATGACTCCATCGACGCAGCA
GTGATCGCTAAGATACTGCGCGCAAACGGCATCCTGGACACCGAGCCTTACCGCAAGCTGGGACGCAACCAGCTGCGCAT
CGGTATGTTCCCAGCGATCGATTCCACCGATGTGGAAAAGCTCACCGGAGCAATCGACTTCATCCTCGATGGCGGTTTTG
CAAGGAAGTAA

Upstream 100 bases:

>100_bases
GGGTGCTAGGAACTGACAGCTTCAGGGTTATAGTTGTTGGGTCAGATCGTTAACGATCCCTGGCCCTTTTACTTCCAAGC
GCAGAAAGTTGCCCGAAGAC

Downstream 100 bases:

>100_bases
TACCCCCACTTTGAAAAACACCCCGTACAGTTACACCAGTACGGGGTGTTTTTTAGTTAAGCTTGGGTGATCACTTAACC
CAGCTAGAAGGAGTCAACAT

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MTDFPTLPSEFIPGDGRFGCGPSKVRPEQIQAIVDGSASVIGTSHRQPAVKNVVGSIREGLSDLFSLPEGYEIILSLGGA
TAFWDAATFGLIEKKSGHLSFGEFSSKFAKASKLAPWLDEPEIVTAETGDSPAPQAFEGADVIAWAHNETSTGAMVPVLR
PEGSEGSLVAIDATSGAGGLPVDIKNSDVYYFSPQKCFASDGGLWLAAMSPAALERIEKINASDRFIPEFLNLQTAVDNS
LKNQTYNTPAVATLLMLDNQVKWMNSNGGLDGMVARTTASSSALYNWAEAREEASPYVADAAKRSLVVGTIDFDDSIDAA
VIAKILRANGILDTEPYRKLGRNQLRIGMFPAIDSTDVEKLTGAIDFILDGGFARK

Sequences:

>Translated_376_residues
MTDFPTLPSEFIPGDGRFGCGPSKVRPEQIQAIVDGSASVIGTSHRQPAVKNVVGSIREGLSDLFSLPEGYEIILSLGGA
TAFWDAATFGLIEKKSGHLSFGEFSSKFAKASKLAPWLDEPEIVTAETGDSPAPQAFEGADVIAWAHNETSTGAMVPVLR
PEGSEGSLVAIDATSGAGGLPVDIKNSDVYYFSPQKCFASDGGLWLAAMSPAALERIEKINASDRFIPEFLNLQTAVDNS
LKNQTYNTPAVATLLMLDNQVKWMNSNGGLDGMVARTTASSSALYNWAEAREEASPYVADAAKRSLVVGTIDFDDSIDAA
VIAKILRANGILDTEPYRKLGRNQLRIGMFPAIDSTDVEKLTGAIDFILDGGFARK
>Mature_375_residues
TDFPTLPSEFIPGDGRFGCGPSKVRPEQIQAIVDGSASVIGTSHRQPAVKNVVGSIREGLSDLFSLPEGYEIILSLGGAT
AFWDAATFGLIEKKSGHLSFGEFSSKFAKASKLAPWLDEPEIVTAETGDSPAPQAFEGADVIAWAHNETSTGAMVPVLRP
EGSEGSLVAIDATSGAGGLPVDIKNSDVYYFSPQKCFASDGGLWLAAMSPAALERIEKINASDRFIPEFLNLQTAVDNSL
KNQTYNTPAVATLLMLDNQVKWMNSNGGLDGMVARTTASSSALYNWAEAREEASPYVADAAKRSLVVGTIDFDDSIDAAV
IAKILRANGILDTEPYRKLGRNQLRIGMFPAIDSTDVEKLTGAIDFILDGGFARK

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=389, Percent_Identity=22.6221079691517, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21356589, Length=361, Percent_Identity=22.9916897506925, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR006272
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 40046; Mature: 39915

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFPTLPSEFIPGDGRFGCGPSKVRPEQIQAIVDGSASVIGTSHRQPAVKNVVGSIREG
CCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHH
LSDLFSLPEGYEIILSLGGATAFWDAATFGLIEKKSGHLSFGEFSSKFAKASKLAPWLDE
HHHHHCCCCCEEEEEECCCCHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCCCCC
PEIVTAETGDSPAPQAFEGADVIAWAHNETSTGAMVPVLRPEGSEGSLVAIDATSGAGGL
CCEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCC
PVDIKNSDVYYFSPQKCFASDGGLWLAAMSPAALERIEKINASDRFIPEFLNLQTAVDNS
EEEEECCEEEEECCHHHHCCCCCEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LKNQTYNTPAVATLLMLDNQVKWMNSNGGLDGMVARTTASSSALYNWAEAREEASPYVAD
HHCCCCCCHHHHEEEHHCCCEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHH
AAKRSLVVGTIDFDDSIDAAVIAKILRANGILDTEPYRKLGRNQLRIGMFPAIDSTDVEK
HHCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEECCCCCCHHHH
LTGAIDFILDGGFARK
HHHHHHHEECCCCCCC
>Mature Secondary Structure 
TDFPTLPSEFIPGDGRFGCGPSKVRPEQIQAIVDGSASVIGTSHRQPAVKNVVGSIREG
CCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHH
LSDLFSLPEGYEIILSLGGATAFWDAATFGLIEKKSGHLSFGEFSSKFAKASKLAPWLDE
HHHHHCCCCCEEEEEECCCCHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCCCCC
PEIVTAETGDSPAPQAFEGADVIAWAHNETSTGAMVPVLRPEGSEGSLVAIDATSGAGGL
CCEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCC
PVDIKNSDVYYFSPQKCFASDGGLWLAAMSPAALERIEKINASDRFIPEFLNLQTAVDNS
EEEEECCEEEEECCHHHHCCCCCEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LKNQTYNTPAVATLLMLDNQVKWMNSNGGLDGMVARTTASSSALYNWAEAREEASPYVAD
HHCCCCCCHHHHEEEHHCCCEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHH
AAKRSLVVGTIDFDDSIDAAVIAKILRANGILDTEPYRKLGRNQLRIGMFPAIDSTDVEK
HHCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEECCCCCCHHHH
LTGAIDFILDGGFARK
HHHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA