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The map label for this gene is suhB [H]

Identifier: 62389690

GI number: 62389690

Start: 843776

End: 844651

Strand: Reverse

Name: suhB [H]

Synonym: cg0911

Alternate gene names: 62389690

Gene position: 844651-843776 (Counterclockwise)

Preceding gene: 62389697

Following gene: 62389689

Centisome position: 25.73

GC content: 59.47

Gene sequence:

>876_bases
ATGGAAGGCATGACTAATCCAGAGCAGACACATCCCGCTGCAAGCCTCGAAGACATGATCAAAACCATCACAAAGACCTT
CGTGATTGCTCACGATCAGGATTCTGATGAGCATCTTGCGCAGGCACTGGTGTACAACGCTGGACGTTTGGCATGGGGCA
TGCGCGAAAACGGTGTGGATACGGATTACAAGACTTCTGTGTCTGATGTGGTCACGGATGCCGATCGTGCGGCCGAGGCC
TTCGTCGCAGGCGTTCTTGAAGCGTTGCGGCCTGAGGACGGCGTGCTTGGCGAGGAAGGCGCGGACCGGGCGTCGAAAAG
CGGAAAAACCTGGGTCATCGACCCGGTTGATGGCACCTACAACTTCACCCAGGGCTCAGATTATTGGTGCTCGGCGCTCG
CGCTGGTCGAGGGCGATCCATCCGCGCCATCGCGCGTGCTTTTCGGCGCCGTACACCGCCCAGCCATGGGTTATACGTGG
TTCGGTGGCCCGGGAATCCGCACCACGCTCGACGGCAAGGAGCTAGATTTGCTTGTCGACGCCCCCCTCAATCAAATCTC
CTTGGCCACCTACATCCACCCGTCACGCATCGCGGAACCTGATATTCAAAAGGCGTGGATGAGCGTTGCCACCCACCCTG
CAACGCTGCGCATGTTCGGCGCCGGCTCCATCGATTTGGCCAACATCGCCGACGGCAGCATCGGCGCATGGGTGCAGCAC
AGCGTCGCAGATTGGGACTGGCTACCCGGCCGCGCACTCATCGAAGGCGTCGGCGGAGCATGCATCAAAGTGACCGCCGG
CGGCGTCGAATGGTCCGTTGCAGGAAACGCGGAAGCAGTTAGTGAGATCTCCGAAACTTTAAGCGCACTAGACTAA

Upstream 100 bases:

>100_bases
CTGCAGAAAATTCGGGACGCATGATTGCACATATTACCCGCACCGATTGTGATTCTTAGAACGCCACCTTATTCAGCACA
CTTGGCCGACGGCATGCACA

Downstream 100 bases:

>100_bases
CAACACATGAGCAAATATGCAGACGATTTAGCCTTAGCCCTCGAACTTGCCGAACTTGCCGATTCCATCACCCTCGACCG
CTTCGAAGCCTCTGACCTGG

Product: inositol monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MEGMTNPEQTHPAASLEDMIKTITKTFVIAHDQDSDEHLAQALVYNAGRLAWGMRENGVDTDYKTSVSDVVTDADRAAEA
FVAGVLEALRPEDGVLGEEGADRASKSGKTWVIDPVDGTYNFTQGSDYWCSALALVEGDPSAPSRVLFGAVHRPAMGYTW
FGGPGIRTTLDGKELDLLVDAPLNQISLATYIHPSRIAEPDIQKAWMSVATHPATLRMFGAGSIDLANIADGSIGAWVQH
SVADWDWLPGRALIEGVGGACIKVTAGGVEWSVAGNAEAVSEISETLSALD

Sequences:

>Translated_291_residues
MEGMTNPEQTHPAASLEDMIKTITKTFVIAHDQDSDEHLAQALVYNAGRLAWGMRENGVDTDYKTSVSDVVTDADRAAEA
FVAGVLEALRPEDGVLGEEGADRASKSGKTWVIDPVDGTYNFTQGSDYWCSALALVEGDPSAPSRVLFGAVHRPAMGYTW
FGGPGIRTTLDGKELDLLVDAPLNQISLATYIHPSRIAEPDIQKAWMSVATHPATLRMFGAGSIDLANIADGSIGAWVQH
SVADWDWLPGRALIEGVGGACIKVTAGGVEWSVAGNAEAVSEISETLSALD
>Mature_291_residues
MEGMTNPEQTHPAASLEDMIKTITKTFVIAHDQDSDEHLAQALVYNAGRLAWGMRENGVDTDYKTSVSDVVTDADRAAEA
FVAGVLEALRPEDGVLGEEGADRASKSGKTWVIDPVDGTYNFTQGSDYWCSALALVEGDPSAPSRVLFGAVHRPAMGYTW
FGGPGIRTTLDGKELDLLVDAPLNQISLATYIHPSRIAEPDIQKAWMSVATHPATLRMFGAGSIDLANIADGSIGAWVQH
SVADWDWLPGRALIEGVGGACIKVTAGGVEWSVAGNAEAVSEISETLSALD

Specific function: Displays a 20-fold higher rate of hydrolysis of the D isoform of inositol 1-phosphate than of the L isoform [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=238, Percent_Identity=22.6890756302521, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI7657236, Length=213, Percent_Identity=24.4131455399061, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI221625487, Length=238, Percent_Identity=22.6890756302521, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788882, Length=211, Percent_Identity=25.1184834123223, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320493, Length=232, Percent_Identity=25.4310344827586, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21357329, Length=279, Percent_Identity=24.3727598566308, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24664926, Length=227, Percent_Identity=25.1101321585903, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24664922, Length=230, Percent_Identity=23.0434782608696, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21357303, Length=264, Percent_Identity=26.1363636363636, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 30914; Mature: 30914

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGMTNPEQTHPAASLEDMIKTITKTFVIAHDQDSDEHLAQALVYNAGRLAWGMRENGVD
CCCCCCCHHCCCHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCCHHEECCCCCCCC
TDYKTSVSDVVTDADRAAEAFVAGVLEALRPEDGVLGEEGADRASKSGKTWVIDPVDGTY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCEEEEECCCCCE
NFTQGSDYWCSALALVEGDPSAPSRVLFGAVHRPAMGYTWFGGPGIRTTLDGKELDLLVD
ECCCCCCHHEEEEEEEECCCCCCHHHHHHHHCCCCCCEEEECCCCCEEEECCCEEEEEEC
APLNQISLATYIHPSRIAEPDIQKAWMSVATHPATLRMFGAGSIDLANIADGSIGAWVQH
CCCCCEEEEEEECHHHCCCHHHHHHHHHHHCCCCEEEEECCCCEEECCCCCCCCCHHHHH
SVADWDWLPGRALIEGVGGACIKVTAGGVEWSVAGNAEAVSEISETLSALD
CCCCCCCCCCHHHHHCCCCEEEEEEECCEEEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEGMTNPEQTHPAASLEDMIKTITKTFVIAHDQDSDEHLAQALVYNAGRLAWGMRENGVD
CCCCCCCHHCCCHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCCHHEECCCCCCCC
TDYKTSVSDVVTDADRAAEAFVAGVLEALRPEDGVLGEEGADRASKSGKTWVIDPVDGTY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCEEEEECCCCCE
NFTQGSDYWCSALALVEGDPSAPSRVLFGAVHRPAMGYTWFGGPGIRTTLDGKELDLLVD
ECCCCCCHHEEEEEEEECCCCCCHHHHHHHHCCCCCCEEEECCCCCEEEECCCEEEEEEC
APLNQISLATYIHPSRIAEPDIQKAWMSVATHPATLRMFGAGSIDLANIADGSIGAWVQH
CCCCCEEEEEEECHHHCCCHHHHHHHHHHHCCCCEEEEECCCCEEECCCCCCCCCHHHHH
SVADWDWLPGRALIEGVGGACIKVTAGGVEWSVAGNAEAVSEISETLSALD
CCCCCCCCCCHHHHHCCCCEEEEEEECCEEEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9720201; 10360571; 10508089 [H]