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The map label for this gene is pyc [H]

Identifier: 62389578

GI number: 62389578

Start: 706684

End: 710106

Strand: Direct

Name: pyc [H]

Synonym: cg0791

Alternate gene names: 62389578

Gene position: 706684-710106 (Clockwise)

Preceding gene: 62389577

Following gene: 62389579

Centisome position: 21.53

GC content: 56.76

Gene sequence:

>3423_bases
GTGTCGACTCACACATCTTCAACGCTTCCAGCATTCAAAAAGATCTTGGTAGCAAACCGCGGCGAAATCGCGGTCCGTGC
TTTCCGTGCAGCACTCGAAACCGGTGCAGCCACGGTAGCTATTTACCCCCGTGAAGATCGGGGATCATTCCACCGCTCTT
TTGCTTCTGAAGCTGTCCGCATTGGTACCGAAGGCTCACCAGTCAAGGCGTACCTGGACATCGATGAAATTATCGGTGCA
GCTAAAAAAGTTAAAGCAGATGCCATTTACCCGGGATACGGCTTCCTGTCTGAAAATGCCCAGCTTGCCCGCGAGTGTGC
GGAAAACGGCATTACTTTTATTGGCCCAACCCCAGAGGTTCTTGATCTCACCGGTGATAAGTCTCGCGCGGTAACCGCCG
CGAAGAAGGCTGGTCTGCCAGTTTTGGCGGAATCCACCCCGAGCAAAAACATCGATGAGATCGTTAAAAGCGCTGAAGGC
CAGACTTACCCCATCTTTGTGAAGGCAGTTGCCGGTGGTGGCGGACGCGGTATGCGTTTTGTTGCTTCACCTGATGAGCT
TCGCAAATTAGCAACAGAAGCATCTCGTGAAGCTGAAGCGGCTTTCGGCGATGGCGCGGTATATGTCGAACGTGCTGTGA
TTAACCCTCAGCATATTGAAGTGCAGATCCTTGGCGATCACACTGGAGAAGTTGTACACCTTTATGAACGTGACTGCTCA
CTGCAGCGTCGTCACCAAAAAGTTGTCGAAATTGCGCCAGCACAGCATTTGGATCCAGAACTGCGTGATCGCATTTGTGC
GGATGCAGTAAAGTTCTGCCGCTCCATTGGTTACCAGGGCGCGGGAACCGTGGAATTCTTGGTCGATGAAAAGGGCAACC
ACGTCTTCATCGAAATGAACCCACGTATCCAGGTTGAGCACACCGTGACTGAAGAAGTCACCGAGGTGGACCTGGTGAAG
GCGCAGATGCGCTTGGCTGCTGGTGCAACCTTGAAGGAATTGGGTCTGACCCAAGATAAGATCAAGACCCACGGTGCAGC
ACTGCAGTGCCGCATCACCACGGAAGATCCAAACAACGGCTTCCGCCCAGATACCGGAACTATCACCGCGTACCGCTCAC
CAGGCGGAGCTGGCGTTCGTCTTGACGGTGCAGCTCAGCTCGGTGGCGAAATCACCGCACACTTTGACTCCATGCTGGTG
AAAATGACCTGCCGTGGTTCCGACTTTGAAACTGCTGTTGCTCGTGCACAGCGCGCGTTGGCTGAGTTCACCGTGTCTGG
TGTTGCAACCAACATTGGTTTCTTGCGTGCGTTGCTGCGGGAAGAGGACTTCACTTCCAAGCGCATCGCCACCGGATTCA
TTGCCGATCACCCGCACCTCCTTCAGGCTCCACCTGCTGATGATGAGCAGGGACGCATCCTGGATTACTTGGCAGATGTC
ACCGTGAACAAGCCTCATGGTGTGCGTCCAAAGGATGTTGCAGCTCCTATCGATAAGCTGCCTAACATCAAGGATCTGCC
ACTGCCACGCGGTTCCCGTGACCGCCTGAAGCAGCTTGGCCCAGCCGCGTTTGCTCGTGATCTCCGTGAGCAGGACGCAC
TGGCAGTTACTGATACCACCTTCCGCGATGCACACCAGTCTTTGCTTGCGACCCGAGTCCGCTCATTCGCACTGAAGCCT
GCGGCAGAGGCCGTCGCAAAGCTGACTCCTGAGCTTTTGTCCGTGGAGGCCTGGGGCGGCGCGACCTACGATGTGGCGAT
GCGTTTCCTCTTTGAGGATCCGTGGGACAGGCTCGACGAGCTGCGCGAGGCGATGCCGAATGTAAACATTCAGATGCTGC
TTCGCGGCCGCAACACCGTGGGATACACCCCGTACCCAGACTCCGTCTGCCGCGCGTTTGTTAAGGAAGCTGCCAGCTCC
GGCGTGGACATCTTCCGCATCTTCGACGCGCTTAACGACGTCTCCCAGATGCGTCCAGCAATCGACGCAGTCCTGGAGAC
CAACACCGCGGTAGCCGAGGTGGCTATGGCTTATTCTGGTGATCTCTCTGATCCAAATGAAAAGCTCTACACCCTGGATT
ACTACCTAAAGATGGCAGAGGAGATCGTCAAGTCTGGCGCTCACATCTTGGCCATTAAGGATATGGCTGGTCTGCTTCGC
CCAGCTGCGGTAACCAAGCTGGTCACCGCACTGCGCCGTGAATTCGATCTGCCAGTGCACGTGCACACCCACGACACTGC
GGGTGGCCAGCTGGCAACCTACTTTGCTGCAGCTCAAGCTGGTGCAGATGCTGTTGACGGTGCTTCCGCACCACTGTCTG
GCACCACCTCCCAGCCATCCCTGTCTGCCATTGTTGCTGCATTCGCGCACACCCGTCGCGATACCGGTTTGAGCCTCGAG
GCTGTTTCTGACCTCGAGCCGTACTGGGAAGCAGTGCGCGGACTGTACCTGCCATTTGAGTCTGGAACCCCAGGCCCAAC
CGGTCGCGTCTACCGCCACGAAATCCCAGGCGGACAGTTGTCCAACCTGCGTGCACAGGCCACCGCACTGGGCCTTGCGG
ATCGTTTCGAACTCATCGAAGACAACTACGCAGCCGTTAATGAGATGCTGGGACGCCCAACCAAGGTCACCCCATCCTCC
AAGGTTGTTGGCGACCTCGCACTCCACCTCGTTGGTGCGGGTGTGGATCCAGCAGACTTTGCTGCCGATCCACAAAAGTA
CGACATCCCAGACTCTGTCATCGCGTTCCTGCGCGGCGAGCTTGGTAACCCTCCAGGTGGCTGGCCAGAGCCACTGCGCA
CCCGCGCACTGGAAGGCCGCTCCGAAGGCAAGGCACCTCTGACGGAAGTTCCTGAGGAAGAGCAGGCGCACCTCGACGCT
GATGATTCCAAGGAACGTCGCAATAGCCTCAACCGCCTGCTGTTCCCGAAGCCAACCGAAGAGTTCCTCGAGCACCGTCG
CCGCTTCGGCAACACCTCTGCGCTGGATGATCGTGAATTCTTCTACGGCCTGGTCGAAGGCCGCGAGACTTTGATCCGCC
TGCCAGATGTGCGCACCCCACTGCTTGTTCGCCTGGATGCGATCTCTGAGCCAGACGATAAGGGTATGCGCAATGTTGTG
GCCAACGTCAACGGCCAGATCCGCCCAATGCGTGTGCGTGACCGCTCCGTTGAGTCTGTCACCGCAACCGCAGAAAAGGC
AGATTCCTCCAACAAGGGCCATGTTGCTGCACCATTCGCTGGTGTTGTCACCGTGACTGTTGCTGAAGGTGATGAGGTCA
AGGCTGGAGATGCAGTCGCAATCATCGAGGCTATGAAGATGGAAGCAACAATCACTGCTTCTGTTGACGGCAAAATCGAT
CGCGTTGTGGTTCCTGCTGCAACGAAGGTGGAAGGTGGCGACTTGATCGTCGTCGTTTCCTAA

Upstream 100 bases:

>100_bases
AAAACCGATGTTTGATTGGGGGAATCGGGGGTTACGATACTAGGACGCAGTGACTGCTATCACCCTTGGCGGTCTCTTGT
TGAAAGGAATAATTACTCTA

Downstream 100 bases:

>100_bases
ACCTTTCTGTAAAAAGCCCCGCGTCTTCCTCATGGAGGAGGCGGGGCTTTTTGGGCCAAGATGGGAGATGGGTGAGTTGG
ATTTGGTCTGATTCGACACT

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1140; Mature: 1139

Protein sequence:

>1140_residues
MSTHTSSTLPAFKKILVANRGEIAVRAFRAALETGAATVAIYPREDRGSFHRSFASEAVRIGTEGSPVKAYLDIDEIIGA
AKKVKADAIYPGYGFLSENAQLARECAENGITFIGPTPEVLDLTGDKSRAVTAAKKAGLPVLAESTPSKNIDEIVKSAEG
QTYPIFVKAVAGGGGRGMRFVASPDELRKLATEASREAEAAFGDGAVYVERAVINPQHIEVQILGDHTGEVVHLYERDCS
LQRRHQKVVEIAPAQHLDPELRDRICADAVKFCRSIGYQGAGTVEFLVDEKGNHVFIEMNPRIQVEHTVTEEVTEVDLVK
AQMRLAAGATLKELGLTQDKIKTHGAALQCRITTEDPNNGFRPDTGTITAYRSPGGAGVRLDGAAQLGGEITAHFDSMLV
KMTCRGSDFETAVARAQRALAEFTVSGVATNIGFLRALLREEDFTSKRIATGFIADHPHLLQAPPADDEQGRILDYLADV
TVNKPHGVRPKDVAAPIDKLPNIKDLPLPRGSRDRLKQLGPAAFARDLREQDALAVTDTTFRDAHQSLLATRVRSFALKP
AAEAVAKLTPELLSVEAWGGATYDVAMRFLFEDPWDRLDELREAMPNVNIQMLLRGRNTVGYTPYPDSVCRAFVKEAASS
GVDIFRIFDALNDVSQMRPAIDAVLETNTAVAEVAMAYSGDLSDPNEKLYTLDYYLKMAEEIVKSGAHILAIKDMAGLLR
PAAVTKLVTALRREFDLPVHVHTHDTAGGQLATYFAAAQAGADAVDGASAPLSGTTSQPSLSAIVAAFAHTRRDTGLSLE
AVSDLEPYWEAVRGLYLPFESGTPGPTGRVYRHEIPGGQLSNLRAQATALGLADRFELIEDNYAAVNEMLGRPTKVTPSS
KVVGDLALHLVGAGVDPADFAADPQKYDIPDSVIAFLRGELGNPPGGWPEPLRTRALEGRSEGKAPLTEVPEEEQAHLDA
DDSKERRNSLNRLLFPKPTEEFLEHRRRFGNTSALDDREFFYGLVEGRETLIRLPDVRTPLLVRLDAISEPDDKGMRNVV
ANVNGQIRPMRVRDRSVESVTATAEKADSSNKGHVAAPFAGVVTVTVAEGDEVKAGDAVAIIEAMKMEATITASVDGKID
RVVVPAATKVEGGDLIVVVS

Sequences:

>Translated_1140_residues
MSTHTSSTLPAFKKILVANRGEIAVRAFRAALETGAATVAIYPREDRGSFHRSFASEAVRIGTEGSPVKAYLDIDEIIGA
AKKVKADAIYPGYGFLSENAQLARECAENGITFIGPTPEVLDLTGDKSRAVTAAKKAGLPVLAESTPSKNIDEIVKSAEG
QTYPIFVKAVAGGGGRGMRFVASPDELRKLATEASREAEAAFGDGAVYVERAVINPQHIEVQILGDHTGEVVHLYERDCS
LQRRHQKVVEIAPAQHLDPELRDRICADAVKFCRSIGYQGAGTVEFLVDEKGNHVFIEMNPRIQVEHTVTEEVTEVDLVK
AQMRLAAGATLKELGLTQDKIKTHGAALQCRITTEDPNNGFRPDTGTITAYRSPGGAGVRLDGAAQLGGEITAHFDSMLV
KMTCRGSDFETAVARAQRALAEFTVSGVATNIGFLRALLREEDFTSKRIATGFIADHPHLLQAPPADDEQGRILDYLADV
TVNKPHGVRPKDVAAPIDKLPNIKDLPLPRGSRDRLKQLGPAAFARDLREQDALAVTDTTFRDAHQSLLATRVRSFALKP
AAEAVAKLTPELLSVEAWGGATYDVAMRFLFEDPWDRLDELREAMPNVNIQMLLRGRNTVGYTPYPDSVCRAFVKEAASS
GVDIFRIFDALNDVSQMRPAIDAVLETNTAVAEVAMAYSGDLSDPNEKLYTLDYYLKMAEEIVKSGAHILAIKDMAGLLR
PAAVTKLVTALRREFDLPVHVHTHDTAGGQLATYFAAAQAGADAVDGASAPLSGTTSQPSLSAIVAAFAHTRRDTGLSLE
AVSDLEPYWEAVRGLYLPFESGTPGPTGRVYRHEIPGGQLSNLRAQATALGLADRFELIEDNYAAVNEMLGRPTKVTPSS
KVVGDLALHLVGAGVDPADFAADPQKYDIPDSVIAFLRGELGNPPGGWPEPLRTRALEGRSEGKAPLTEVPEEEQAHLDA
DDSKERRNSLNRLLFPKPTEEFLEHRRRFGNTSALDDREFFYGLVEGRETLIRLPDVRTPLLVRLDAISEPDDKGMRNVV
ANVNGQIRPMRVRDRSVESVTATAEKADSSNKGHVAAPFAGVVTVTVAEGDEVKAGDAVAIIEAMKMEATITASVDGKID
RVVVPAATKVEGGDLIVVVS
>Mature_1139_residues
STHTSSTLPAFKKILVANRGEIAVRAFRAALETGAATVAIYPREDRGSFHRSFASEAVRIGTEGSPVKAYLDIDEIIGAA
KKVKADAIYPGYGFLSENAQLARECAENGITFIGPTPEVLDLTGDKSRAVTAAKKAGLPVLAESTPSKNIDEIVKSAEGQ
TYPIFVKAVAGGGGRGMRFVASPDELRKLATEASREAEAAFGDGAVYVERAVINPQHIEVQILGDHTGEVVHLYERDCSL
QRRHQKVVEIAPAQHLDPELRDRICADAVKFCRSIGYQGAGTVEFLVDEKGNHVFIEMNPRIQVEHTVTEEVTEVDLVKA
QMRLAAGATLKELGLTQDKIKTHGAALQCRITTEDPNNGFRPDTGTITAYRSPGGAGVRLDGAAQLGGEITAHFDSMLVK
MTCRGSDFETAVARAQRALAEFTVSGVATNIGFLRALLREEDFTSKRIATGFIADHPHLLQAPPADDEQGRILDYLADVT
VNKPHGVRPKDVAAPIDKLPNIKDLPLPRGSRDRLKQLGPAAFARDLREQDALAVTDTTFRDAHQSLLATRVRSFALKPA
AEAVAKLTPELLSVEAWGGATYDVAMRFLFEDPWDRLDELREAMPNVNIQMLLRGRNTVGYTPYPDSVCRAFVKEAASSG
VDIFRIFDALNDVSQMRPAIDAVLETNTAVAEVAMAYSGDLSDPNEKLYTLDYYLKMAEEIVKSGAHILAIKDMAGLLRP
AAVTKLVTALRREFDLPVHVHTHDTAGGQLATYFAAAQAGADAVDGASAPLSGTTSQPSLSAIVAAFAHTRRDTGLSLEA
VSDLEPYWEAVRGLYLPFESGTPGPTGRVYRHEIPGGQLSNLRAQATALGLADRFELIEDNYAAVNEMLGRPTKVTPSSK
VVGDLALHLVGAGVDPADFAADPQKYDIPDSVIAFLRGELGNPPGGWPEPLRTRALEGRSEGKAPLTEVPEEEQAHLDAD
DSKERRNSLNRLLFPKPTEEFLEHRRRFGNTSALDDREFFYGLVEGRETLIRLPDVRTPLLVRLDAISEPDDKGMRNVVA
NVNGQIRPMRVRDRSVESVTATAEKADSSNKGHVAAPFAGVVTVTVAEGDEVKAGDAVAIIEAMKMEATITASVDGKIDR
VVVPAATKVEGGDLIVVVS

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1140, Percent_Identity=46.7543859649123, Blast_Score=969, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1140, Percent_Identity=46.7543859649123, Blast_Score=969, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1140, Percent_Identity=46.7543859649123, Blast_Score=969, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=456, Percent_Identity=41.2280701754386, Blast_Score=360, Evalue=5e-99,
Organism=Homo sapiens, GI189095269, Length=452, Percent_Identity=42.6991150442478, Blast_Score=331, Evalue=2e-90,
Organism=Homo sapiens, GI65506442, Length=448, Percent_Identity=42.6339285714286, Blast_Score=328, Evalue=2e-89,
Organism=Homo sapiens, GI295821183, Length=448, Percent_Identity=42.6339285714286, Blast_Score=327, Evalue=3e-89,
Organism=Homo sapiens, GI38679960, Length=507, Percent_Identity=29.585798816568, Blast_Score=224, Evalue=5e-58,
Organism=Homo sapiens, GI38679971, Length=505, Percent_Identity=29.7029702970297, Blast_Score=223, Evalue=6e-58,
Organism=Homo sapiens, GI38679974, Length=505, Percent_Identity=29.7029702970297, Blast_Score=223, Evalue=6e-58,
Organism=Homo sapiens, GI38679977, Length=507, Percent_Identity=29.585798816568, Blast_Score=223, Evalue=7e-58,
Organism=Homo sapiens, GI38679967, Length=507, Percent_Identity=29.585798816568, Blast_Score=223, Evalue=7e-58,
Organism=Homo sapiens, GI134142062, Length=508, Percent_Identity=28.5433070866142, Blast_Score=211, Evalue=3e-54,
Organism=Escherichia coli, GI1789654, Length=433, Percent_Identity=46.189376443418, Blast_Score=345, Evalue=1e-95,
Organism=Escherichia coli, GI1786216, Length=250, Percent_Identity=28.8, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17562816, Length=1150, Percent_Identity=45.1304347826087, Blast_Score=949, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=466, Percent_Identity=40.9871244635193, Blast_Score=323, Evalue=3e-88,
Organism=Caenorhabditis elegans, GI17567343, Length=459, Percent_Identity=39.2156862745098, Blast_Score=313, Evalue=3e-85,
Organism=Caenorhabditis elegans, GI133931226, Length=486, Percent_Identity=29.8353909465021, Blast_Score=216, Evalue=8e-56,
Organism=Caenorhabditis elegans, GI71997168, Length=503, Percent_Identity=27.037773359841, Blast_Score=194, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI71997163, Length=504, Percent_Identity=26.984126984127, Blast_Score=194, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1166, Percent_Identity=45.5403087478559, Blast_Score=934, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1160, Percent_Identity=46.4655172413793, Blast_Score=930, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=450, Percent_Identity=37.3333333333333, Blast_Score=303, Evalue=1e-82,
Organism=Saccharomyces cerevisiae, GI6323863, Length=456, Percent_Identity=30.9210526315789, Blast_Score=204, Evalue=5e-53,
Organism=Saccharomyces cerevisiae, GI6324343, Length=512, Percent_Identity=28.515625, Blast_Score=197, Evalue=6e-51,
Organism=Saccharomyces cerevisiae, GI6322569, Length=235, Percent_Identity=23.4042553191489, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24652212, Length=1155, Percent_Identity=44.2424242424242, Blast_Score=936, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1155, Percent_Identity=44.2424242424242, Blast_Score=936, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1155, Percent_Identity=44.2424242424242, Blast_Score=936, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1155, Percent_Identity=44.2424242424242, Blast_Score=936, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1155, Percent_Identity=44.2424242424242, Blast_Score=936, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1165, Percent_Identity=44.0343347639485, Blast_Score=930, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1165, Percent_Identity=44.0343347639485, Blast_Score=930, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1165, Percent_Identity=44.0343347639485, Blast_Score=930, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1165, Percent_Identity=44.0343347639485, Blast_Score=930, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1165, Percent_Identity=44.0343347639485, Blast_Score=930, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=467, Percent_Identity=39.186295503212, Blast_Score=330, Evalue=3e-90,
Organism=Drosophila melanogaster, GI24651759, Length=418, Percent_Identity=38.9952153110048, Blast_Score=295, Evalue=9e-80,
Organism=Drosophila melanogaster, GI161076407, Length=503, Percent_Identity=27.8330019880716, Blast_Score=197, Evalue=4e-50,
Organism=Drosophila melanogaster, GI24586460, Length=503, Percent_Identity=27.8330019880716, Blast_Score=197, Evalue=4e-50,
Organism=Drosophila melanogaster, GI24586458, Length=503, Percent_Identity=27.8330019880716, Blast_Score=197, Evalue=4e-50,
Organism=Drosophila melanogaster, GI161076409, Length=503, Percent_Identity=27.8330019880716, Blast_Score=197, Evalue=5e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 123105; Mature: 122973

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS50975 ATP_GRASP ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTHTSSTLPAFKKILVANRGEIAVRAFRAALETGAATVAIYPREDRGSFHRSFASEAVR
CCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHE
IGTEGSPVKAYLDIDEIIGAAKKVKADAIYPGYGFLSENAQLARECAENGITFIGPTPEV
ECCCCCCEEEEEEHHHHHCHHHHHCCCEECCCCCCCCCCHHHHHHHHHCCCEEECCCCCE
LDLTGDKSRAVTAAKKAGLPVLAESTPSKNIDEIVKSAEGQTYPIFVKAVAGGGGRGMRF
EECCCCCCHHHHHHHHCCCEEEECCCCCCCHHHHHHHCCCCEEEEEEEEEECCCCCCCEE
VASPDELRKLATEASREAEAAFGDGAVYVERAVINPQHIEVQILGDHTGEVVHLYERDCS
ECCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEEECCCCCEEEEEHHCCH
LQRRHQKVVEIAPAQHLDPELRDRICADAVKFCRSIGYQGAGTVEFLVDEKGNHVFIEMN
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEC
PRIQVEHTVTEEVTEVDLVKAQMRLAAGATLKELGLTQDKIKTHGAALQCRITTEDPNNG
CCEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHCCCEEEEEEEECCCCCC
FRPDTGTITAYRSPGGAGVRLDGAAQLGGEITAHFDSMLVKMTCRGSDFETAVARAQRAL
CCCCCCCEEEEECCCCCCEEECCHHHCCCCHHHHHHHEEEEEEECCCCHHHHHHHHHHHH
AEFTVSGVATNIGFLRALLREEDFTSKRIATGFIADHPHLLQAPPADDEQGRILDYLADV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEECCCCCEECCCCCCCCCCHHHHHHHHC
TVNKPHGVRPKDVAAPIDKLPNIKDLPLPRGSRDRLKQLGPAAFARDLREQDALAVTDTT
EECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCEEEECCH
FRDAHQSLLATRVRSFALKPAAEAVAKLTPELLSVEAWGGATYDVAMRFLFEDPWDRLDE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHEEECCCCCHHHHHHHHHHCCHHHHHHH
LREAMPNVNIQMLLRGRNTVGYTPYPDSVCRAFVKEAASSGVDIFRIFDALNDVSQMRPA
HHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IDAVLETNTAVAEVAMAYSGDLSDPNEKLYTLDYYLKMAEEIVKSGAHILAIKDMAGLLR
HHHHHHCCHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHCCCEEEEEHHHHHHHH
PAAVTKLVTALRREFDLPVHVHTHDTAGGQLATYFAAAQAGADAVDGASAPLSGTTSQPS
HHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
LSAIVAAFAHTRRDTGLSLEAVSDLEPYWEAVRGLYLPFESGTPGPTGRVYRHEIPGGQL
HHHHHHHHHHHHCCCCCCHHHHHHCHHHHHHHHCEEEEECCCCCCCCCCEEEEECCCCCH
SNLRAQATALGLADRFELIEDNYAAVNEMLGRPTKVTPSSKVVGDLALHLVGAGVDPADF
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHH
AADPQKYDIPDSVIAFLRGELGNPPGGWPEPLRTRALEGRSEGKAPLTEVPEEEQAHLDA
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHCCCC
DDSKERRNSLNRLLFPKPTEEFLEHRRRFGNTSALDDREFFYGLVEGRETLIRLPDVRTP
CCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHEEECCCCCCC
LLVRLDAISEPDDKGMRNVVANVNGQIRPMRVRDRSVESVTATAEKADSSNKGHVAAPFA
CEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEECCCC
GVVTVTVAEGDEVKAGDAVAIIEAMKMEATITASVDGKIDRVVVPAATKVEGGDLIVVVS
CEEEEEEECCCCCCCCCHHHHHHHHHHCEEEEEECCCCCCEEEECCCCEECCCCEEEEEC
>Mature Secondary Structure 
STHTSSTLPAFKKILVANRGEIAVRAFRAALETGAATVAIYPREDRGSFHRSFASEAVR
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHE
IGTEGSPVKAYLDIDEIIGAAKKVKADAIYPGYGFLSENAQLARECAENGITFIGPTPEV
ECCCCCCEEEEEEHHHHHCHHHHHCCCEECCCCCCCCCCHHHHHHHHHCCCEEECCCCCE
LDLTGDKSRAVTAAKKAGLPVLAESTPSKNIDEIVKSAEGQTYPIFVKAVAGGGGRGMRF
EECCCCCCHHHHHHHHCCCEEEECCCCCCCHHHHHHHCCCCEEEEEEEEEECCCCCCCEE
VASPDELRKLATEASREAEAAFGDGAVYVERAVINPQHIEVQILGDHTGEVVHLYERDCS
ECCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEEECCCCCEEEEEHHCCH
LQRRHQKVVEIAPAQHLDPELRDRICADAVKFCRSIGYQGAGTVEFLVDEKGNHVFIEMN
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEC
PRIQVEHTVTEEVTEVDLVKAQMRLAAGATLKELGLTQDKIKTHGAALQCRITTEDPNNG
CCEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHCCCEEEEEEEECCCCCC
FRPDTGTITAYRSPGGAGVRLDGAAQLGGEITAHFDSMLVKMTCRGSDFETAVARAQRAL
CCCCCCCEEEEECCCCCCEEECCHHHCCCCHHHHHHHEEEEEEECCCCHHHHHHHHHHHH
AEFTVSGVATNIGFLRALLREEDFTSKRIATGFIADHPHLLQAPPADDEQGRILDYLADV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEECCCCCEECCCCCCCCCCHHHHHHHHC
TVNKPHGVRPKDVAAPIDKLPNIKDLPLPRGSRDRLKQLGPAAFARDLREQDALAVTDTT
EECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCEEEECCH
FRDAHQSLLATRVRSFALKPAAEAVAKLTPELLSVEAWGGATYDVAMRFLFEDPWDRLDE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHEEECCCCCHHHHHHHHHHCCHHHHHHH
LREAMPNVNIQMLLRGRNTVGYTPYPDSVCRAFVKEAASSGVDIFRIFDALNDVSQMRPA
HHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IDAVLETNTAVAEVAMAYSGDLSDPNEKLYTLDYYLKMAEEIVKSGAHILAIKDMAGLLR
HHHHHHCCHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHCCCEEEEEHHHHHHHH
PAAVTKLVTALRREFDLPVHVHTHDTAGGQLATYFAAAQAGADAVDGASAPLSGTTSQPS
HHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
LSAIVAAFAHTRRDTGLSLEAVSDLEPYWEAVRGLYLPFESGTPGPTGRVYRHEIPGGQL
HHHHHHHHHHHHCCCCCCHHHHHHCHHHHHHHHCEEEEECCCCCCCCCCEEEEECCCCCH
SNLRAQATALGLADRFELIEDNYAAVNEMLGRPTKVTPSSKVVGDLALHLVGAGVDPADF
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHH
AADPQKYDIPDSVIAFLRGELGNPPGGWPEPLRTRALEGRSEGKAPLTEVPEEEQAHLDA
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHCCCC
DDSKERRNSLNRLLFPKPTEEFLEHRRRFGNTSALDDREFFYGLVEGRETLIRLPDVRTP
CCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHEEECCCCCCC
LLVRLDAISEPDDKGMRNVVANVNGQIRPMRVRDRSVESVTATAEKADSSNKGHVAAPFA
CEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEECCCC
GVVTVTVAEGDEVKAGDAVAIIEAMKMEATITASVDGKIDRVVVPAATKVEGGDLIVVVS
CEEEEEEECCCCCCCCCHHHHHHHHHHCEEEEEECCCCCCEEEECCCCEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]