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The map label for this gene is groEL' [H]

Identifier: 62389487

GI number: 62389487

Start: 610660

End: 611034

Strand: Direct

Name: groEL' [H]

Synonym: cg0691

Alternate gene names: 62389487

Gene position: 610660-611034 (Clockwise)

Preceding gene: 62389486

Following gene: 62389488

Centisome position: 18.6

GC content: 58.67

Gene sequence:

>375_bases
ATGGCAAAGCTCATTGCTTTTGACCAGGACGCCCGCGAAGGCATTCTCCGGGGCGTTGACGCTCTGGCAAACGCTGTCAA
GGTAACCCTCGGCCCACGCGGCCGTAACGTGGTTCTTGATAAGGCATTCGGCGGACCTCTGGTCACCAACGACGGTGTCA
CCATTGCCCGCGACATCGACCTTGAGGATCCTTTTGAGAACCTCGGTGCGCAGCTGGTGAAGTCCGTTGCTGTTAAGACC
AACGACATCGCTGGTGACGGCACCACGACTGCAACTCTGCTTGCTCAGGCACTCATTGCTGAAGGCCTGCGCAACGTTGC
TGCTGGCGCAAACCGGCCCTTCCGGTTTTGGGGTACATCACAGAACCTGGGCTAG

Upstream 100 bases:

>100_bases
CCCGTTACGGCGGCACCGAGATCAAGTTCGGTGGCGTGGAGTACTTGCTTCTCTCCGCTCGTGACATCCTCGCAATCGTC
GAGAAGTAGGGGATAAGTTC

Downstream 100 bases:

>100_bases
CGGTGTAGACCCGAAAATAAACGAGCCTTTTGTCAGGGTTAAGGTTTAGGTATCTAAGCTAACCAAACACCAACAAAAGG
CTCTACCCATGAAGTCTACC

Product: 60 kDa chaperonin (protein CPN60) (HSP60)-N-terminal fragment

Products: NA

Alternate protein names: GroEL protein 1; Protein Cpn60 1 [H]

Number of amino acids: Translated: 124; Mature: 123

Protein sequence:

>124_residues
MAKLIAFDQDAREGILRGVDALANAVKVTLGPRGRNVVLDKAFGGPLVTNDGVTIARDIDLEDPFENLGAQLVKSVAVKT
NDIAGDGTTTATLLAQALIAEGLRNVAAGANRPFRFWGTSQNLG

Sequences:

>Translated_124_residues
MAKLIAFDQDAREGILRGVDALANAVKVTLGPRGRNVVLDKAFGGPLVTNDGVTIARDIDLEDPFENLGAQLVKSVAVKT
NDIAGDGTTTATLLAQALIAEGLRNVAAGANRPFRFWGTSQNLG
>Mature_123_residues
AKLIAFDQDAREGILRGVDALANAVKVTLGPRGRNVVLDKAFGGPLVTNDGVTIARDIDLEDPFENLGAQLVKSVAVKTN
DIAGDGTTTATLLAQALIAEGLRNVAAGANRPFRFWGTSQNLG

Specific function: Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions [H]

COG id: COG0459

COG function: function code O; Chaperonin GroEL (HSP60 family)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chaperonin (HSP60) family [H]

Homologues:

Organism=Homo sapiens, GI41399285, Length=110, Percent_Identity=53.6363636363636, Blast_Score=122, Evalue=7e-29,
Organism=Homo sapiens, GI31542947, Length=110, Percent_Identity=53.6363636363636, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI1790586, Length=110, Percent_Identity=69.0909090909091, Blast_Score=154, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI193210679, Length=111, Percent_Identity=49.5495495495495, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17555558, Length=110, Percent_Identity=50, Blast_Score=118, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6323288, Length=119, Percent_Identity=51.2605042016807, Blast_Score=123, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24641193, Length=110, Percent_Identity=52.7272727272727, Blast_Score=122, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24641191, Length=110, Percent_Identity=52.7272727272727, Blast_Score=122, Evalue=5e-29,
Organism=Drosophila melanogaster, GI45550936, Length=110, Percent_Identity=51.8181818181818, Blast_Score=119, Evalue=6e-28,
Organism=Drosophila melanogaster, GI45550132, Length=110, Percent_Identity=51.8181818181818, Blast_Score=119, Evalue=6e-28,
Organism=Drosophila melanogaster, GI45550935, Length=110, Percent_Identity=51.8181818181818, Blast_Score=119, Evalue=6e-28,
Organism=Drosophila melanogaster, GI17864606, Length=110, Percent_Identity=50, Blast_Score=108, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24584129, Length=100, Percent_Identity=42, Blast_Score=89, Evalue=8e-19,
Organism=Drosophila melanogaster, GI19921262, Length=100, Percent_Identity=42, Blast_Score=89, Evalue=8e-19,

Paralogues:

None

Copy number: 2180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 15012 Molecules/Cell In: Growth Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018370
- InterPro:   IPR001844
- InterPro:   IPR002423 [H]

Pfam domain/function: PF00118 Cpn60_TCP1 [H]

EC number: NA

Molecular weight: Translated: 12959; Mature: 12828

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLIAFDQDAREGILRGVDALANAVKVTLGPRGRNVVLDKAFGGPLVTNDGVTIARDID
CCCEEECCCHHHHHHHHHHHHHHHHEEEEECCCCCEEEEECCCCCCEEECCCEEEEEECC
LEDPFENLGAQLVKSVAVKTNDIAGDGTTTATLLAQALIAEGLRNVAAGANRPFRFWGTS
CCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
QNLG
CCCC
>Mature Secondary Structure 
AKLIAFDQDAREGILRGVDALANAVKVTLGPRGRNVVLDKAFGGPLVTNDGVTIARDID
CCEEECCCHHHHHHHHHHHHHHHHEEEEECCCCCEEEEECCCCCCEEECCCEEEEEECC
LEDPFENLGAQLVKSVAVKTNDIAGDGTTTATLLAQALIAEGLRNVAAGANRPFRFWGTS
CCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
QNLG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA