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The map label for this gene is fepG [H]

Identifier: 62389397

GI number: 62389397

Start: 529588

End: 530754

Strand: Reverse

Name: fepG [H]

Synonym: cg0590

Alternate gene names: 62389397

Gene position: 530754-529588 (Counterclockwise)

Preceding gene: 62389398

Following gene: 62389396

Centisome position: 16.17

GC content: 56.56

Gene sequence:

>1167_bases
GTGGTCTTTAATATCAAATCTAGAACTGATGAAACTCCTGTTGCTGCGTCTGAGCCGGTGGAATCCACTAGACCTGTGTC
TGAAGCTTCGACAAGCCCTGCGCTTAACCCCGGCTACCACGCAGTTTCAGTGCAGAGGCGCCGGTTCTCTTTCCGCATCC
CAGCCCGCCTCATGGTGGTTAGCCTTATCCTTTTCGCCATCGCGCTATGCAGCGCCACATGGGCTATCACGATGGGCGAT
TACCCACTGTCTTTGGGGCAGGTGATTAATGCACTTGCTGGCACCGGCGAGAAATTCCAGTTGTTGGTGGTGCGGGAATG
GCGTCTACCTGTAGCCATTGCTGCTGTTGTCTTCGGCGCGCTGCTTGGCATAGGTGGAGCGATTTTCCAGTCGATTACTC
GAAACCCGTTGGGTTCACCTGACGTGATTGGTTTCGATGCAGGTTCTTACACGGCGGTGGTTCTTGTCATTTTGGTCCTC
GGCAACACTCACTACTGGAGCATCGCTTTCGCTGCCATCGTCGGTGGCATTGTTACCGCCTTTGCCGTGTATGTCCTGGC
GTGGCGTAAAGGTGTGCAAGGTTTCCGCTTGATCATCGTGGGCATCGGTGTCTCGGCCATGCTCAGTTCCGTTAACGCGT
ATCTAATCACCCGCGCCGATGTGGAAGACGCCATGGTTGTGGGCTTCTGGAGTGCCGGTTCCATCAACCGCATTACCTGG
CAATCTCTGCTCCCCTCTCTGGTGATCGCTGCTGTCATCATCGTGGCCGCCATTGTGCTGGCAAGGTCACTGCGTTTCAT
GGAAATGGGCGATGACGTAGCCACCACCCTCGGTGTGAAAACAAACTCCACCCGCTTGGCACTCATCGTTGTCGGCGTTG
CTACCTCCGCGTTGGTTACAGCAGCTGCCGGACCGATCTCCTTCATCGCGTTGGTTGCCCCACAGCTGGCACGTCGCCTC
ACTAAAACCCCTGGTGTCAGCCTGGTTGCTGCCGCTGCAATGGGTTCCGCACTGCTCAGCTGCGCTCACCTCCTTTCCCT
GATTATCAGCTCCTTCTACCGCACCATCCCGGTTGGCCTGTTGACTGTATCCATCGGTGGTTGCTACATGATCTGGCTTC
TGCTGCGCGAAACCCGCCGCCAATACCGCACCGGCACCATCCGATAG

Upstream 100 bases:

>100_bases
GGACGCATCATCGCCCGCCCCGGCGAAATTGAAGTAGGCATTGTTACCGCAGTCATCGGCGCACCTGTCCTGATCGCACT
AGTTCGACGGAGGAAAGCCA

Downstream 100 bases:

>100_bases
TTCTTTTAAGGATCCCTCATGAATAACCGCCTGACCATGGAAGACGTCACCATGGCGTATGACAACCGCGTCATCGCCGA
ACACCTCAACGTCACCATCC

Product: cobalamin/Fe3+-siderophores transport system, permease component

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MVFNIKSRTDETPVAASEPVESTRPVSEASTSPALNPGYHAVSVQRRRFSFRIPARLMVVSLILFAIALCSATWAITMGD
YPLSLGQVINALAGTGEKFQLLVVREWRLPVAIAAVVFGALLGIGGAIFQSITRNPLGSPDVIGFDAGSYTAVVLVILVL
GNTHYWSIAFAAIVGGIVTAFAVYVLAWRKGVQGFRLIIVGIGVSAMLSSVNAYLITRADVEDAMVVGFWSAGSINRITW
QSLLPSLVIAAVIIVAAIVLARSLRFMEMGDDVATTLGVKTNSTRLALIVVGVATSALVTAAAGPISFIALVAPQLARRL
TKTPGVSLVAAAAMGSALLSCAHLLSLIISSFYRTIPVGLLTVSIGGCYMIWLLLRETRRQYRTGTIR

Sequences:

>Translated_388_residues
MVFNIKSRTDETPVAASEPVESTRPVSEASTSPALNPGYHAVSVQRRRFSFRIPARLMVVSLILFAIALCSATWAITMGD
YPLSLGQVINALAGTGEKFQLLVVREWRLPVAIAAVVFGALLGIGGAIFQSITRNPLGSPDVIGFDAGSYTAVVLVILVL
GNTHYWSIAFAAIVGGIVTAFAVYVLAWRKGVQGFRLIIVGIGVSAMLSSVNAYLITRADVEDAMVVGFWSAGSINRITW
QSLLPSLVIAAVIIVAAIVLARSLRFMEMGDDVATTLGVKTNSTRLALIVVGVATSALVTAAAGPISFIALVAPQLARRL
TKTPGVSLVAAAAMGSALLSCAHLLSLIISSFYRTIPVGLLTVSIGGCYMIWLLLRETRRQYRTGTIR
>Mature_388_residues
MVFNIKSRTDETPVAASEPVESTRPVSEASTSPALNPGYHAVSVQRRRFSFRIPARLMVVSLILFAIALCSATWAITMGD
YPLSLGQVINALAGTGEKFQLLVVREWRLPVAIAAVVFGALLGIGGAIFQSITRNPLGSPDVIGFDAGSYTAVVLVILVL
GNTHYWSIAFAAIVGGIVTAFAVYVLAWRKGVQGFRLIIVGIGVSAMLSSVNAYLITRADVEDAMVVGFWSAGSINRITW
QSLLPSLVIAAVIIVAAIVLARSLRFMEMGDDVATTLGVKTNSTRLALIVVGVATSALVTAAAGPISFIALVAPQLARRL
TKTPGVSLVAAAAMGSALLSCAHLLSLIISSFYRTIPVGLLTVSIGGCYMIWLLLRETRRQYRTGTIR

Specific function: Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4779

COG function: function code P; ABC-type enterobactin transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786804, Length=326, Percent_Identity=46.0122699386503, Blast_Score=248, Evalue=5e-67,
Organism=Escherichia coli, GI1790740, Length=324, Percent_Identity=30.8641975308642, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786347, Length=275, Percent_Identity=30.5454545454545, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786805, Length=234, Percent_Identity=30.7692307692308, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790741, Length=279, Percent_Identity=27.2401433691756, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788004, Length=280, Percent_Identity=25.3571428571429, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 41106; Mature: 41106

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFNIKSRTDETPVAASEPVESTRPVSEASTSPALNPGYHAVSVQRRRFSFRIPARLMVV
CEEECCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCHHEEEHHHHHEECCCHHHHHH
SLILFAIALCSATWAITMGDYPLSLGQVINALAGTGEKFQLLVVREWRLPVAIAAVVFGA
HHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHH
LLGIGGAIFQSITRNPLGSPDVIGFDAGSYTAVVLVILVLGNTHYWSIAFAAIVGGIVTA
HHHCCHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FAVYVLAWRKGVQGFRLIIVGIGVSAMLSSVNAYLITRADVEDAMVVGFWSAGSINRITW
HHHHHHHHHHCCCCEEEEEECCCHHHHHHHCHHEEEEECCCCCEEEEEEECCCCCCHHHH
QSLLPSLVIAAVIIVAAIVLARSLRFMEMGDDVATTLGVKTNSTRLALIVVGVATSALVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCEEEEEEEHHHHHHHHH
AAAGPISFIALVAPQLARRLTKTPGVSLVAAAAMGSALLSCAHLLSLIISSFYRTIPVGL
HCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTVSIGGCYMIWLLLRETRRQYRTGTIR
HHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVFNIKSRTDETPVAASEPVESTRPVSEASTSPALNPGYHAVSVQRRRFSFRIPARLMVV
CEEECCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCHHEEEHHHHHEECCCHHHHHH
SLILFAIALCSATWAITMGDYPLSLGQVINALAGTGEKFQLLVVREWRLPVAIAAVVFGA
HHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHH
LLGIGGAIFQSITRNPLGSPDVIGFDAGSYTAVVLVILVLGNTHYWSIAFAAIVGGIVTA
HHHCCHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FAVYVLAWRKGVQGFRLIIVGIGVSAMLSSVNAYLITRADVEDAMVVGFWSAGSINRITW
HHHHHHHHHHCCCCEEEEEECCCHHHHHHHCHHEEEEECCCCCEEEEEEECCCCCCHHHH
QSLLPSLVIAAVIIVAAIVLARSLRFMEMGDDVATTLGVKTNSTRLALIVVGVATSALVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCEEEEEEEHHHHHHHHH
AAAGPISFIALVAPQLARRLTKTPGVSLVAAAAMGSALLSCAHLLSLIISSFYRTIPVGL
HCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTVSIGGCYMIWLLLRETRRQYRTGTIR
HHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1838574; 9278503 [H]