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The map label for this gene is fepD [H]

Identifier: 62389398

GI number: 62389398

Start: 530744

End: 531790

Strand: Reverse

Name: fepD [H]

Synonym: cg0591

Alternate gene names: 62389398

Gene position: 531790-530744 (Counterclockwise)

Preceding gene: 62389411

Following gene: 62389397

Centisome position: 16.2

GC content: 58.17

Gene sequence:

>1047_bases
ATGACGGCGGTGGCGGTAGAGAAGCAGAAGGAGACGTCGATAAGCAAAAACCTCGGCAGGCGCCGAGCGCTGGGCATTCT
CGGAATCGTCGTGGCACTGGGTGCGCTTATTGTTTTAAGTATTGCTGTGGGTGCGAACCCACTTTCTTTTAGCTCCGTAT
GGCAGGGTTTTACCGCACACGACAGCTCTGAGGCGTCGATTATCGTGTGGTCAATGCGTATTCCGCGCACGCTGGTGGGC
ATCGTGACTGGCGCTGCTTTTGGTGTGGCGGGTGCTTTAATTCAAGCGCTGACGCGCAACCCGCTTGCCGATCCCGGAAT
TTTGGGAGTTAACGCGGGTGCAGGTTTCGCAGTGACCGTAGGTGTCGGATTTTTCGGACTCAGCAGCGTGACGGGCTACA
TCTGGTTCGCATTCCTGGGCGCTGCCGCCGCTACCCTGCTGGTGTATTTCATTGGTGCGAGCACCAGCGGCAGCGTTAAT
CCTGTTGCTCTGGTCCTCGCCGGCGTTGCTCTGGCCGCCGTGCTTGGTGGCGTCACGAGCTTCCTCACACTGATTGATCC
TGAGACTTTTGAAAGCATCCGCAATTGGAATCTTGGTTCTGTTGCACGCACCGACCTCAGCGACACCATGACCGTATTGC
CATTCCTGGCAGTCGGACTGGCCATCGCGCTCCTGCTGTCGGGAGCACTGAACTCCATTGCGCTTGGCGATGACCTTGCT
GCATCCCTGGGCACCAAAGTGATGCGCACCCGCGTGCTCGGCATCATTTCAGTCACCTTGTTGGCCGGCGGCGCGACCGC
CCTTACTGGTGGTATCGGCTTCGTAGGCCTTATGGTTCCCCACGTTGTGCGCTGGGTAGTTGGCCCCGATCAACGATGGA
TCATCACCTTCAGCGCCCTGTGCGCCCCTGTTCTTGTACTCGGCGCAGACATTTTGGGACGCATCATCGCCCGCCCCGGC
GAAATTGAAGTAGGCATTGTTACCGCAGTCATCGGCGCACCTGTCCTGATCGCACTAGTTCGACGGAGGAAAGCCAGTGG
TCTTTAA

Upstream 100 bases:

>100_bases
CTCACCTAAGATGTTCTAAGCGTTTTAGTTTCAGCTAGTTTTAAGGACTTTCGATGTCTCATACTTTTCTTTCCCCCTCG
ATCTTTAGGAGTCACGCGAT

Downstream 100 bases:

>100_bases
TATCAAATCTAGAACTGATGAAACTCCTGTTGCTGCGTCTGAGCCGGTGGAATCCACTAGACCTGTGTCTGAAGCTTCGA
CAAGCCCTGCGCTTAACCCC

Product: cobalamin/Fe3+-siderophores transport system, permease component

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MTAVAVEKQKETSISKNLGRRRALGILGIVVALGALIVLSIAVGANPLSFSSVWQGFTAHDSSEASIIVWSMRIPRTLVG
IVTGAAFGVAGALIQALTRNPLADPGILGVNAGAGFAVTVGVGFFGLSSVTGYIWFAFLGAAAATLLVYFIGASTSGSVN
PVALVLAGVALAAVLGGVTSFLTLIDPETFESIRNWNLGSVARTDLSDTMTVLPFLAVGLAIALLLSGALNSIALGDDLA
ASLGTKVMRTRVLGIISVTLLAGGATALTGGIGFVGLMVPHVVRWVVGPDQRWIITFSALCAPVLVLGADILGRIIARPG
EIEVGIVTAVIGAPVLIALVRRRKASGL

Sequences:

>Translated_348_residues
MTAVAVEKQKETSISKNLGRRRALGILGIVVALGALIVLSIAVGANPLSFSSVWQGFTAHDSSEASIIVWSMRIPRTLVG
IVTGAAFGVAGALIQALTRNPLADPGILGVNAGAGFAVTVGVGFFGLSSVTGYIWFAFLGAAAATLLVYFIGASTSGSVN
PVALVLAGVALAAVLGGVTSFLTLIDPETFESIRNWNLGSVARTDLSDTMTVLPFLAVGLAIALLLSGALNSIALGDDLA
ASLGTKVMRTRVLGIISVTLLAGGATALTGGIGFVGLMVPHVVRWVVGPDQRWIITFSALCAPVLVLGADILGRIIARPG
EIEVGIVTAVIGAPVLIALVRRRKASGL
>Mature_347_residues
TAVAVEKQKETSISKNLGRRRALGILGIVVALGALIVLSIAVGANPLSFSSVWQGFTAHDSSEASIIVWSMRIPRTLVGI
VTGAAFGVAGALIQALTRNPLADPGILGVNAGAGFAVTVGVGFFGLSSVTGYIWFAFLGAAAATLLVYFIGASTSGSVNP
VALVLAGVALAAVLGGVTSFLTLIDPETFESIRNWNLGSVARTDLSDTMTVLPFLAVGLAIALLLSGALNSIALGDDLAA
SLGTKVMRTRVLGIISVTLLAGGATALTGGIGFVGLMVPHVVRWVVGPDQRWIITFSALCAPVLVLGADILGRIIARPGE
IEVGIVTAVIGAPVLIALVRRRKASGL

Specific function: Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=327, Percent_Identity=48.9296636085627, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1790740, Length=316, Percent_Identity=33.5443037974684, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1790741, Length=286, Percent_Identity=34.965034965035, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786804, Length=305, Percent_Identity=32.7868852459016, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788004, Length=285, Percent_Identity=31.5789473684211, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1786347, Length=320, Percent_Identity=30.3125, Blast_Score=101, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35400; Mature: 35269

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVAVEKQKETSISKNLGRRRALGILGIVVALGALIVLSIAVGANPLSFSSVWQGFTAH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCC
DSSEASIIVWSMRIPRTLVGIVTGAAFGVAGALIQALTRNPLADPGILGVNAGAGFAVTV
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEE
GVGFFGLSSVTGYIWFAFLGAAAATLLVYFIGASTSGSVNPVALVLAGVALAAVLGGVTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FLTLIDPETFESIRNWNLGSVARTDLSDTMTVLPFLAVGLAIALLLSGALNSIALGDDLA
HHHHCCHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ASLGTKVMRTRVLGIISVTLLAGGATALTGGIGFVGLMVPHVVRWVVGPDQRWIITFSAL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHH
CAPVLVLGADILGRIIARPGEIEVGIVTAVIGAPVLIALVRRRKASGL
HHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TAVAVEKQKETSISKNLGRRRALGILGIVVALGALIVLSIAVGANPLSFSSVWQGFTAH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCC
DSSEASIIVWSMRIPRTLVGIVTGAAFGVAGALIQALTRNPLADPGILGVNAGAGFAVTV
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEE
GVGFFGLSSVTGYIWFAFLGAAAATLLVYFIGASTSGSVNPVALVLAGVALAAVLGGVTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FLTLIDPETFESIRNWNLGSVARTDLSDTMTVLPFLAVGLAIALLLSGALNSIALGDDLA
HHHHCCHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ASLGTKVMRTRVLGIISVTLLAGGATALTGGIGFVGLMVPHVVRWVVGPDQRWIITFSAL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHH
CAPVLVLGADILGRIIARPGEIEVGIVTAVIGAPVLIALVRRRKASGL
HHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1838574; 1787794; 9278503 [H]