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The map label for this gene is tagA2 [H]

Identifier: 62389039

GI number: 62389039

Start: 157585

End: 158142

Strand: Direct

Name: tagA2 [H]

Synonym: cg0182

Alternate gene names: 62389039

Gene position: 157585-158142 (Clockwise)

Preceding gene: 62389038

Following gene: 62389040

Centisome position: 4.8

GC content: 49.28

Gene sequence:

>558_bases
ATGTCCCATGCTCAAATTATGGTTCGCGCCATGACAACAAACAAAGCTAATCCAAATGAACTTGTAATCTGCGCTGATGA
AAAGTCACGGCCCCGCTGGGCATCTAGAAGTGAGCTGTGTTGGGAGTATTTCGACAATGAGTGGGGCAGACCTCCGGTGG
ATCTCAATGCTCTTTTTGAGATCTTGACGTTGGTAGTTTTCCAAGTGGGTGTCACCTGGCATGCTGTGCTGTCCAAACGG
GAAGGGTTCCGTCAAGCATTCGCCCAATTCGATGTTGCAAAAGTAGCCGCCTTCAATGAGGACGACGTGGAACGCCTACT
TGATGATCTACAGATTTTTAGAAACCGAAGAAAAATCAACGCTGCCATCACCAATGCCAAAGCGTTGCTGGAGTTAAACG
ATGAAACAGGCACCTTTGACTCAATTATTGCCGACCACTCAACTGACGCCACAGCCATGGTGAAGCATCTCAAAGCCTTG
GGCTTTACCCATATCGGACTGACCTCCTTGAGCATCCTCCAGCAGGCCATTGGGGTCACAGAGCTGAAGGCTGCCTAA

Upstream 100 bases:

>100_bases
GGATGCGGGTTGAAAGAAGGGCGAATCAACATCACGATCCGCCAACTTGCACTATAAAACTCCAGGTAGAGGTATGTCTC
GGGGGTGAAATAGCCCCGCA

Downstream 100 bases:

>100_bases
GATATAACTCCGATGACAACAGCACAGTTTCTAGCGCTTTTTCTGGTGTGGATCGCAGCAATTGCATCCCCTGGGCCAGA
CCTTTTCCAGATCATCAGGC

Product: DNA-3-methyladenine glycosylase I protein

Products: NA

Alternate protein names: 3-methyladenine-DNA glycosylase I, constitutive; TAG I; DNA-3-methyladenine glycosidase I; DNA-3-methyladenine glycosylase I [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MSHAQIMVRAMTTNKANPNELVICADEKSRPRWASRSELCWEYFDNEWGRPPVDLNALFEILTLVVFQVGVTWHAVLSKR
EGFRQAFAQFDVAKVAAFNEDDVERLLDDLQIFRNRRKINAAITNAKALLELNDETGTFDSIIADHSTDATAMVKHLKAL
GFTHIGLTSLSILQQAIGVTELKAA

Sequences:

>Translated_185_residues
MSHAQIMVRAMTTNKANPNELVICADEKSRPRWASRSELCWEYFDNEWGRPPVDLNALFEILTLVVFQVGVTWHAVLSKR
EGFRQAFAQFDVAKVAAFNEDDVERLLDDLQIFRNRRKINAAITNAKALLELNDETGTFDSIIADHSTDATAMVKHLKAL
GFTHIGLTSLSILQQAIGVTELKAA
>Mature_184_residues
SHAQIMVRAMTTNKANPNELVICADEKSRPRWASRSELCWEYFDNEWGRPPVDLNALFEILTLVVFQVGVTWHAVLSKRE
GFRQAFAQFDVAKVAAFNEDDVERLLDDLQIFRNRRKINAAITNAKALLELNDETGTFDSIIADHSTDATAMVKHLKALG
FTHIGLTSLSILQQAIGVTELKAA

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789971, Length=169, Percent_Identity=38.4615384615385, Blast_Score=110, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005019
- InterPro:   IPR011257
- InterPro:   IPR004597 [H]

Pfam domain/function: PF03352 Adenine_glyco [H]

EC number: =3.2.2.20 [H]

Molecular weight: Translated: 20758; Mature: 20627

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHAQIMVRAMTTNKANPNELVICADEKSRPRWASRSELCWEYFDNEWGRPPVDLNALFE
CCCHHEEEEEHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHH
ILTLVVFQVGVTWHAVLSKREGFRQAFAQFDVAKVAAFNEDDVERLLDDLQIFRNRRKIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AAITNAKALLELNDETGTFDSIIADHSTDATAMVKHLKALGFTHIGLTSLSILQQAIGVT
HHHHCCEEEEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHH
ELKAA
HHCCC
>Mature Secondary Structure 
SHAQIMVRAMTTNKANPNELVICADEKSRPRWASRSELCWEYFDNEWGRPPVDLNALFE
CCHHEEEEEHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHH
ILTLVVFQVGVTWHAVLSKREGFRQAFAQFDVAKVAAFNEDDVERLLDDLQIFRNRRKIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AAITNAKALLELNDETGTFDSIIADHSTDATAMVKHLKALGFTHIGLTSLSILQQAIGVT
HHHHCCEEEEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHH
ELKAA
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3536912; 3520491; 8041620; 9278503 [H]