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The map label for this gene is pdxH [H]

Identifier: 59714344

GI number: 59714344

Start: 1303770

End: 1304405

Strand: Reverse

Name: pdxH [H]

Synonym: VF_A1161

Alternate gene names: 59714344

Gene position: 1304405-1303770 (Counterclockwise)

Preceding gene: 59714345

Following gene: 59714342

Centisome position: 98.05

GC content: 40.41

Gene sequence:

>636_bases
ATGGAATTAGAAGATATTCGTCGTGATTATAGCCTTGGTGGTTTACGAAGAGCCGATTTACCTCAAGAGCCTGTAGAATT
GTTTGAATTATGGTTAAAACAAGCTGTGGAAGCCAAATTGACCGATCCTACAGCGATGACGGTGGCTACAGTAGATGAGA
ATGGACAACCGTTTCAACGTATTGTGCTATTAAAACATTTTGATAAGACAGGTTTTGTTTTTTATACCAACTTAGGTTCT
CGTAAAGCACAACAGCTAGAGCAACACAGTAAGATATCACTGCATTTCCCATGGCATCCACTTGAGCGTCAGGTTCATAT
TACAGGCACCGCTGAGAAATTAACGGCTCTTGAGAATATGAAATATTTCACATCAAGACCCAAAGAAAGTCAGATAGCCG
CATGGGCAAGTAAACAAAGTAGTCGTTTAACTGCAAGAGCCGCTCTTGAAGGTAAGTACCTAGAGTTAAAACAAAAGTTT
GCAAAAGGAGAGATCCCTGTTCCTAAGTTTTGGGGCGGATTTAGAATTAAGATCGATTCTATAGAGTTTTGGCAGGGAGG
AGATCATCGACTTCATGACCGATTCTTATACAGTAAAGATCAAAATGATTGGCAGATCGATCGTTTAGCGCCATGA

Upstream 100 bases:

>100_bases
TTTAGGGTCTAATTAGGCCCTTTTTTTGTATCACCTCTTGTTTAGCGTGTTTCAAAAGAGCACAATTTAGTCAGCTGGAA
TTAAAGAAGTCGAGATTTAC

Downstream 100 bases:

>100_bases
TCTTGTCGTTATTCACTAGTATTAAAGTTGAAAAAAGCGATGATCTTATGATCATCGCTTTTTTCATGACTTAAAACTCT
TTTAGCCACTCACTATTAAG

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MELEDIRRDYSLGGLRRADLPQEPVELFELWLKQAVEAKLTDPTAMTVATVDENGQPFQRIVLLKHFDKTGFVFYTNLGS
RKAQQLEQHSKISLHFPWHPLERQVHITGTAEKLTALENMKYFTSRPKESQIAAWASKQSSRLTARAALEGKYLELKQKF
AKGEIPVPKFWGGFRIKIDSIEFWQGGDHRLHDRFLYSKDQNDWQIDRLAP

Sequences:

>Translated_211_residues
MELEDIRRDYSLGGLRRADLPQEPVELFELWLKQAVEAKLTDPTAMTVATVDENGQPFQRIVLLKHFDKTGFVFYTNLGS
RKAQQLEQHSKISLHFPWHPLERQVHITGTAEKLTALENMKYFTSRPKESQIAAWASKQSSRLTARAALEGKYLELKQKF
AKGEIPVPKFWGGFRIKIDSIEFWQGGDHRLHDRFLYSKDQNDWQIDRLAP
>Mature_211_residues
MELEDIRRDYSLGGLRRADLPQEPVELFELWLKQAVEAKLTDPTAMTVATVDENGQPFQRIVLLKHFDKTGFVFYTNLGS
RKAQQLEQHSKISLHFPWHPLERQVHITGTAEKLTALENMKYFTSRPKESQIAAWASKQSSRLTARAALEGKYLELKQKF
AKGEIPVPKFWGGFRIKIDSIEFWQGGDHRLHDRFLYSKDQNDWQIDRLAP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=205, Percent_Identity=40.4878048780488, Blast_Score=150, Evalue=6e-37,
Organism=Escherichia coli, GI1787926, Length=210, Percent_Identity=66.6666666666667, Blast_Score=312, Evalue=9e-87,
Organism=Caenorhabditis elegans, GI17553712, Length=221, Percent_Identity=35.7466063348416, Blast_Score=133, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6319509, Length=208, Percent_Identity=38.9423076923077, Blast_Score=139, Evalue=3e-34,
Organism=Drosophila melanogaster, GI45551845, Length=207, Percent_Identity=38.6473429951691, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24644901, Length=207, Percent_Identity=38.6473429951691, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24644903, Length=168, Percent_Identity=32.1428571428571, Blast_Score=88, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 24524; Mature: 24524

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELEDIRRDYSLGGLRRADLPQEPVELFELWLKQAVEAKLTDPTAMTVATVDENGQPFQR
CCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHH
IVLLKHFDKTGFVFYTNLGSRKAQQLEQHSKISLHFPWHPLERQVHITGTAEKLTALENM
HHHHHHCCCCCEEEEECCCCHHHHHHHHCCCEEEECCCCCCCCEEEEECCHHHHHHHHHH
KYFTSRPKESQIAAWASKQSSRLTARAALEGKYLELKQKFAKGEIPVPKFWGGFRIKIDS
HHHHCCCCHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEE
IEFWQGGDHRLHDRFLYSKDQNDWQIDRLAP
EEECCCCCCCHHHHEEECCCCCCEEECCCCC
>Mature Secondary Structure
MELEDIRRDYSLGGLRRADLPQEPVELFELWLKQAVEAKLTDPTAMTVATVDENGQPFQR
CCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHH
IVLLKHFDKTGFVFYTNLGSRKAQQLEQHSKISLHFPWHPLERQVHITGTAEKLTALENM
HHHHHHCCCCCEEEEECCCCHHHHHHHHCCCEEEECCCCCCCCEEEEECCHHHHHHHHHH
KYFTSRPKESQIAAWASKQSSRLTARAALEGKYLELKQKFAKGEIPVPKFWGGFRIKIDS
HHHHCCCCHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEE
IEFWQGGDHRLHDRFLYSKDQNDWQIDRLAP
EEECCCCCCCHHHHEEECCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA