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The map label for this gene is ydhC [H]

Identifier: 59714342

GI number: 59714342

Start: 1301467

End: 1302660

Strand: Reverse

Name: ydhC [H]

Synonym: VF_A1159

Alternate gene names: 59714342

Gene position: 1302660-1301467 (Counterclockwise)

Preceding gene: 59714344

Following gene: 59714337

Centisome position: 97.92

GC content: 38.27

Gene sequence:

>1194_bases
ATGGACAATAAAAAACAATCGATTCCTTATATTTGGCTTGCTGGCCTAAGTATGCTGGGTTTCTTAGCAACTGATATGTA
TCTACCTGCATTCGATATCATCCGTGGTGATCTAGGTACTACTGAAAACATGATTGGTTTAACCCTAAGTATTTTCTTGT
TAGGTATGGCAATTGGTCAACTTTTTTACGGTAGACTAACTCAAAAATTAGGTACAAAAAAATCATTAATCGTTGGTTTA
AGCATTTTTGCAATCAGTAGTTTGGCTGCTTCATTTTCAACCAGTGTAGAAATGTTACTAGTCGCTCGCTTTTTCCAAGC
GTTAGGTGCGTGTAGTGCAAACGTTATTTGGCAAGCAATGGTGATTCAGCGTTATGATGCAAAAACATCACAACGTGTTT
TTGCTACTATCATGCCTCTTGTTGCTCTTTCTCCTGCCTTAGCTCCATTATTGGGTGCAGCAATTGAAAAGTTCTACGGT
TGGTCAATGATTTTCGTAACACTAACTGTGATTGGTGTTGGTCTAGCACTACGTACTTTTGTAGACAAAGAACCAAAACA
AGAAAAAATGACTTCTGAGAAAAGCATTACATTCCGTGATGTTATTAAGTCAAAAAAATTCACAGGTAACATGCTAATTT
ATGCAGCAAGTTCAGCGATCTTCTTTGCATGGTTAACGGGTTCACCGTTTGTAATGACGCAAATGGGCTACTCAGGTGCT
GATATCGGTTTAAGTTATGTTCCACAAACTATTGCATTTATCGTTGGTGGTTACGGTTGCCGTTGGGCACTAGAGCGTTT
TGATGCTCAACAAGTTCTTCCATGGATTTTAAAACTGTCGATTGCAAGCGTGGCTACTGTATTCTTAGTGTCGTGGAGAA
TGGATGTATCTTCTATTATCCCAATGCTAATTCCGTTTTGCTTTTTAGCAGCAGCAAATGGTGCAATTTACCCAATCGTA
GTAAATAACGCATTGGTTGATTTTAAAGAGGGGAGTGCCGTAGCTTCTGGTCTACTAAACTTCTTACAAATGCTTTTCTG
TGTAGCAGCAAGTGCAATGGTTTCAAGCATTAGTTACCTAGGTGCAATCTCTATGGGTAGCATCATGTTATTGCAACTTG
TGTTCTTATTTATTGGTGCTGTAATGGTATTTAAAGTAAATAAAGAAGAAAGAGCGGCATTAGCAACTCAATAA

Upstream 100 bases:

>100_bases
AATAATTTGATGCAAAGTGCAAATTATATCGTTTCACAAGAGTAGCAACTAGCACATAGAATGCAACGAATTTAAAAAAT
GTTCAGCTTTGGAGAAGAAC

Downstream 100 bases:

>100_bases
CCAGTTAATATATTGGTGAATAAAAATAGCATTGAGCGTTATTGCCAATGCTATTTTTTTATCTGAAGGAAAGAGGATTA
TTTCTTTTTTATCATGATAG

Product: inner membrane transport protein YdhC

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MDNKKQSIPYIWLAGLSMLGFLATDMYLPAFDIIRGDLGTTENMIGLTLSIFLLGMAIGQLFYGRLTQKLGTKKSLIVGL
SIFAISSLAASFSTSVEMLLVARFFQALGACSANVIWQAMVIQRYDAKTSQRVFATIMPLVALSPALAPLLGAAIEKFYG
WSMIFVTLTVIGVGLALRTFVDKEPKQEKMTSEKSITFRDVIKSKKFTGNMLIYAASSAIFFAWLTGSPFVMTQMGYSGA
DIGLSYVPQTIAFIVGGYGCRWALERFDAQQVLPWILKLSIASVATVFLVSWRMDVSSIIPMLIPFCFLAAANGAIYPIV
VNNALVDFKEGSAVASGLLNFLQMLFCVAASAMVSSISYLGAISMGSIMLLQLVFLFIGAVMVFKVNKEERAALATQ

Sequences:

>Translated_397_residues
MDNKKQSIPYIWLAGLSMLGFLATDMYLPAFDIIRGDLGTTENMIGLTLSIFLLGMAIGQLFYGRLTQKLGTKKSLIVGL
SIFAISSLAASFSTSVEMLLVARFFQALGACSANVIWQAMVIQRYDAKTSQRVFATIMPLVALSPALAPLLGAAIEKFYG
WSMIFVTLTVIGVGLALRTFVDKEPKQEKMTSEKSITFRDVIKSKKFTGNMLIYAASSAIFFAWLTGSPFVMTQMGYSGA
DIGLSYVPQTIAFIVGGYGCRWALERFDAQQVLPWILKLSIASVATVFLVSWRMDVSSIIPMLIPFCFLAAANGAIYPIV
VNNALVDFKEGSAVASGLLNFLQMLFCVAASAMVSSISYLGAISMGSIMLLQLVFLFIGAVMVFKVNKEERAALATQ
>Mature_397_residues
MDNKKQSIPYIWLAGLSMLGFLATDMYLPAFDIIRGDLGTTENMIGLTLSIFLLGMAIGQLFYGRLTQKLGTKKSLIVGL
SIFAISSLAASFSTSVEMLLVARFFQALGACSANVIWQAMVIQRYDAKTSQRVFATIMPLVALSPALAPLLGAAIEKFYG
WSMIFVTLTVIGVGLALRTFVDKEPKQEKMTSEKSITFRDVIKSKKFTGNMLIYAASSAIFFAWLTGSPFVMTQMGYSGA
DIGLSYVPQTIAFIVGGYGCRWALERFDAQQVLPWILKLSIASVATVFLVSWRMDVSSIIPMLIPFCFLAAANGAIYPIV
VNNALVDFKEGSAVASGLLNFLQMLFCVAASAMVSSISYLGAISMGSIMLLQLVFLFIGAVMVFKVNKEERAALATQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=374, Percent_Identity=49.1978609625668, Blast_Score=341, Evalue=5e-95,
Organism=Escherichia coli, GI1788509, Length=245, Percent_Identity=28.1632653061224, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790146, Length=220, Percent_Identity=26.8181818181818, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790794, Length=222, Percent_Identity=25.6756756756757, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87082312, Length=334, Percent_Identity=23.0538922155689, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43147; Mature: 43147

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNKKQSIPYIWLAGLSMLGFLATDMYLPAFDIIRGDLGTTENMIGLTLSIFLLGMAIGQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LFYGRLTQKLGTKKSLIVGLSIFAISSLAASFSTSVEMLLVARFFQALGACSANVIWQAM
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VIQRYDAKTSQRVFATIMPLVALSPALAPLLGAAIEKFYGWSMIFVTLTVIGVGLALRTF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
VDKEPKQEKMTSEKSITFRDVIKSKKFTGNMLIYAASSAIFFAWLTGSPFVMTQMGYSGA
HCCCCHHHHHHHHCCCHHHHHHHCCCCCCCEEEEEECCEEEEEEECCCCEEEEECCCCCC
DIGLSYVPQTIAFIVGGYGCRWALERFDAQQVLPWILKLSIASVATVFLVSWRMDVSSII
CCCHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
PMLIPFCFLAAANGAIYPIVVNNALVDFKEGSAVASGLLNFLQMLFCVAASAMVSSISYL
HHHHHHHHHHHCCCCEEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAISMGSIMLLQLVFLFIGAVMVFKVNKEERAALATQ
HHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHCCCC
>Mature Secondary Structure
MDNKKQSIPYIWLAGLSMLGFLATDMYLPAFDIIRGDLGTTENMIGLTLSIFLLGMAIGQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LFYGRLTQKLGTKKSLIVGLSIFAISSLAASFSTSVEMLLVARFFQALGACSANVIWQAM
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VIQRYDAKTSQRVFATIMPLVALSPALAPLLGAAIEKFYGWSMIFVTLTVIGVGLALRTF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
VDKEPKQEKMTSEKSITFRDVIKSKKFTGNMLIYAASSAIFFAWLTGSPFVMTQMGYSGA
HCCCCHHHHHHHHCCCHHHHHHHCCCCCCCEEEEEECCEEEEEEECCCCEEEEECCCCCC
DIGLSYVPQTIAFIVGGYGCRWALERFDAQQVLPWILKLSIASVATVFLVSWRMDVSSII
CCCHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
PMLIPFCFLAAANGAIYPIVVNNALVDFKEGSAVASGLLNFLQMLFCVAASAMVSSISYL
HHHHHHHHHHHCCCCEEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAISMGSIMLLQLVFLFIGAVMVFKVNKEERAALATQ
HHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]