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The map label for this gene is kbaZ [H]

Identifier: 59714188

GI number: 59714188

Start: 1128521

End: 1129822

Strand: Reverse

Name: kbaZ [H]

Synonym: VF_A1005

Alternate gene names: 59714188

Gene position: 1129822-1128521 (Counterclockwise)

Preceding gene: 59714189

Following gene: 59714187

Centisome position: 84.93

GC content: 41.32

Gene sequence:

>1302_bases
ATGAACACCTTTCAACATCTTGTACAGCGTCACAAAGCGGGTGAGCAAAACGGAATTTATTCAGTTTGTTCTGCTCATCC
GTTAGTTATCGAAGCGGCGCTTTCTCAAGCTTTAAGTGATGACTCCTTGCTACTTATTGAGGCAACTTCTAATCAAGTTG
ATCAATTTGGTGGCTATACAGGAATGAAGCCTGCTGATTTTCGAGACTTTGTACTACAGCTAGCAAAATCACTTAATTTC
CCAACCGAAAAACTCATTCTTGGTGGTGATCACCTTGGTCCTAATCGTTGGCAGAAACTAACAGCTGCAGAAGCAATGGT
GAATGCTGATGATCTTATCGCCGCTTATGTTGCTGCTGGATTTAAGAAGATCCATTTAGACTGCAGTATGTCTTGTGCCG
ATGATCCAACCCCTCTATCTGATGAAATCGTCGCTGAACGTGCTGCTAGATTGGCTAAAATAGCAGAAGATACGGCAGTT
TCTTCTTTTGGTCATAGCGATCTTGTTTATGTTATTGGTACAGAAGTTCCGGTACCGGGTGGTGCTGCTGAGGAGTTAGA
TACACTTCAAGTTACTTCACCAGAGGCCGCAAGAAAAACCATTCAATCCCATCAATTTGCATTTGAACGAGCAGGCGTAG
CTGATTGTTGGCAACGTGTGGTTGGTTTAGTTGTACAGCCAGGTGTTGAATTTGATCATACTGGTGTTATTGATTATCGT
TCAGAAGAAGCTTTGGAGTTAAGTAAAGTAGTTGATGACTTTGAACACATGGTTTTTGAAGCGCACTCTACAGATTATCA
AACAGATAAAGCGTATCAAGCTCTTGTAAGAGACCATTTTGCTATTTTGAAAGTGGGCCCCGCGCTGACCTTTGCCTTGC
GTGAAGCGTTATACAACCTATGTGATATCGAAGAACAATTGATACCAAAAGCACATTGTTCAGATTTGCGTGAACATATC
GAAAAAGAAATGTGTGACTCTCCAGAATATTGGCAACCATATTATCAAGGTAATGAAGCCCAGCAACGTTTCTCTCGTAG
CTACAGCTTTAGTGATCGCATTCGTTATTACTGGCCAGATGAAAAAATTAATCAGGCGCAGAATACTTTGTTTACTAATT
TATCTCGTAATGGCATTCCGCTTCCATTACTTAGTCAGCATTTATCATCCCAATTTCGCTCGGTTCGTGAAGGGCAATTG
AGCTTAGAACCCAAAGAGCTTGTTCTCGATAAGATCCGTCAAACACTTCGTAGTTATGCGAAGGCTTGTAAACAAAATAA
AGAAGAAGGCGTTGCATTATGA

Upstream 100 bases:

>100_bases
AAGGTCTCCGTGAAATGAAAGTTGAAGTAATCATTGTCGAAAAAGAAAAGTAACCGACCTAACTCCATAGCTGCATTCGG
ATGCAGTATGGAGTTAGTAA

Downstream 100 bases:

>100_bases
ATCACTACCTTGGTTACTCAGAATCAGAATTAGAAACGCTTTCTGGTTTTTGGACTGCGAAAGAAATTACTCAACAACCG
GAAAGTTGGCGCCGAACTGA

Product: tagatose 6-phosphate aldolase 1 subunit KbaZ

Products: ADP; D-tagatose 1,6-bisphosphate

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MNTFQHLVQRHKAGEQNGIYSVCSAHPLVIEAALSQALSDDSLLLIEATSNQVDQFGGYTGMKPADFRDFVLQLAKSLNF
PTEKLILGGDHLGPNRWQKLTAAEAMVNADDLIAAYVAAGFKKIHLDCSMSCADDPTPLSDEIVAERAARLAKIAEDTAV
SSFGHSDLVYVIGTEVPVPGGAAEELDTLQVTSPEAARKTIQSHQFAFERAGVADCWQRVVGLVVQPGVEFDHTGVIDYR
SEEALELSKVVDDFEHMVFEAHSTDYQTDKAYQALVRDHFAILKVGPALTFALREALYNLCDIEEQLIPKAHCSDLREHI
EKEMCDSPEYWQPYYQGNEAQQRFSRSYSFSDRIRYYWPDEKINQAQNTLFTNLSRNGIPLPLLSQHLSSQFRSVREGQL
SLEPKELVLDKIRQTLRSYAKACKQNKEEGVAL

Sequences:

>Translated_433_residues
MNTFQHLVQRHKAGEQNGIYSVCSAHPLVIEAALSQALSDDSLLLIEATSNQVDQFGGYTGMKPADFRDFVLQLAKSLNF
PTEKLILGGDHLGPNRWQKLTAAEAMVNADDLIAAYVAAGFKKIHLDCSMSCADDPTPLSDEIVAERAARLAKIAEDTAV
SSFGHSDLVYVIGTEVPVPGGAAEELDTLQVTSPEAARKTIQSHQFAFERAGVADCWQRVVGLVVQPGVEFDHTGVIDYR
SEEALELSKVVDDFEHMVFEAHSTDYQTDKAYQALVRDHFAILKVGPALTFALREALYNLCDIEEQLIPKAHCSDLREHI
EKEMCDSPEYWQPYYQGNEAQQRFSRSYSFSDRIRYYWPDEKINQAQNTLFTNLSRNGIPLPLLSQHLSSQFRSVREGQL
SLEPKELVLDKIRQTLRSYAKACKQNKEEGVAL
>Mature_433_residues
MNTFQHLVQRHKAGEQNGIYSVCSAHPLVIEAALSQALSDDSLLLIEATSNQVDQFGGYTGMKPADFRDFVLQLAKSLNF
PTEKLILGGDHLGPNRWQKLTAAEAMVNADDLIAAYVAAGFKKIHLDCSMSCADDPTPLSDEIVAERAARLAKIAEDTAV
SSFGHSDLVYVIGTEVPVPGGAAEELDTLQVTSPEAARKTIQSHQFAFERAGVADCWQRVVGLVVQPGVEFDHTGVIDYR
SEEALELSKVVDDFEHMVFEAHSTDYQTDKAYQALVRDHFAILKVGPALTFALREALYNLCDIEEQLIPKAHCSDLREHI
EKEMCDSPEYWQPYYQGNEAQQRFSRSYSFSDRIRYYWPDEKINQAQNTLFTNLSRNGIPLPLLSQHLSSQFRSVREGQL
SLEPKELVLDKIRQTLRSYAKACKQNKEEGVAL

Specific function: Component of the tagatose-1,6-bisphosphate aldolase kbaYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of kbaY. When expressed alone, kbaZ does not show any aldol

COG id: COG4573

COG function: function code G; Predicted tagatose 6-phosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gatZ/kbaZ family. KbaZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789520, Length=424, Percent_Identity=62.2641509433962, Blast_Score=562, Evalue=1e-161,
Organism=Escherichia coli, GI1788411, Length=419, Percent_Identity=52.744630071599, Blast_Score=438, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012062 [H]

Pfam domain/function: PF08013 Tagatose_6_P_K [H]

EC number: 2.7.1.144

Molecular weight: Translated: 48431; Mature: 48431

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTFQHLVQRHKAGEQNGIYSVCSAHPLVIEAALSQALSDDSLLLIEATSNQVDQFGGYT
CCHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHCCCC
GMKPADFRDFVLQLAKSLNFPTEKLILGGDHLGPNRWQKLTAAEAMVNADDLIAAYVAAG
CCCCCCHHHHHHHHHHHCCCCHHHEEECCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHC
FKKIHLDCSMSCADDPTPLSDEIVAERAARLAKIAEDTAVSSFGHSDLVYVIGTEVPVPG
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
GAAEELDTLQVTSPEAARKTIQSHQFAFERAGVADCWQRVVGLVVQPGVEFDHTGVIDYR
CCHHHCCCEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCEECC
SEEALELSKVVDDFEHMVFEAHSTDYQTDKAYQALVRDHFAILKVGPALTFALREALYNL
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CDIEEQLIPKAHCSDLREHIEKEMCDSPEYWQPYYQGNEAQQRFSRSYSFSDRIRYYWPD
HCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHCCCCCCCEEEECCC
EKINQAQNTLFTNLSRNGIPLPLLSQHLSSQFRSVREGQLSLEPKELVLDKIRQTLRSYA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
KACKQNKEEGVAL
HHHHCCCCCCCCC
>Mature Secondary Structure
MNTFQHLVQRHKAGEQNGIYSVCSAHPLVIEAALSQALSDDSLLLIEATSNQVDQFGGYT
CCHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHCCCC
GMKPADFRDFVLQLAKSLNFPTEKLILGGDHLGPNRWQKLTAAEAMVNADDLIAAYVAAG
CCCCCCHHHHHHHHHHHCCCCHHHEEECCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHC
FKKIHLDCSMSCADDPTPLSDEIVAERAARLAKIAEDTAVSSFGHSDLVYVIGTEVPVPG
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
GAAEELDTLQVTSPEAARKTIQSHQFAFERAGVADCWQRVVGLVVQPGVEFDHTGVIDYR
CCHHHCCCEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCEECC
SEEALELSKVVDDFEHMVFEAHSTDYQTDKAYQALVRDHFAILKVGPALTFALREALYNL
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CDIEEQLIPKAHCSDLREHIEKEMCDSPEYWQPYYQGNEAQQRFSRSYSFSDRIRYYWPD
HCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHCCCCCCCEEEECCC
EKINQAQNTLFTNLSRNGIPLPLLSQHLSSQFRSVREGQLSLEPKELVLDKIRQTLRSYA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
KACKQNKEEGVAL
HHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-tagatose 6-phosphate

Specific reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate

General reaction: Phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA