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The map label for this gene is agaR [H]

Identifier: 59714189

GI number: 59714189

Start: 1129870

End: 1130646

Strand: Reverse

Name: agaR [H]

Synonym: VF_A1006

Alternate gene names: 59714189

Gene position: 1130646-1129870 (Counterclockwise)

Preceding gene: 59714193

Following gene: 59714188

Centisome position: 84.99

GC content: 40.41

Gene sequence:

>777_bases
ATGATGAGTGCTGTCGAAAGGCGCATGGAAATCGTAAACGTGGTTAATCAAGATGGTAAAGCACGTGTAGAGGACCTTGC
TGCACGATTTGATGTCTCTAGTGTCACTATTCGCAGTGACCTGAGCTTTTTAGAAAAGAATGGGTATGTTGTTCGTTCTC
ATGGAGCGGCTATTCCAAATACTGGTGTGATTGCTGAACTTACGGTTCATGAGAAACGTCATCAAAATATTGGAACAAAG
TCTTCTATTGGTTACGCAGCGGCACAACTGATTGAAAATGGTGACACCGTTATTCTGGATTCTGGTACGACTACGCGAGA
AATTGCATCTAACTTAAAGTCGTTAGAGCAAGCGGTAGTCATGACTAATGGTCTGGATGTAGCTATGGAATTAGCATCAG
CTTCTGGTATAGAAGTATTGATGTCGGGTGGAGTTCTTCGTAAGAAGGCTCTCTCTTTTTCTGGCTCTCAAGCTGAAGCT
AGCCTAAAAAATTATCGCTTTGATAAAGTGTTTTTGGGTGTTGACGGTTTTGATTTGAGATCGGGTATCACTACACATAA
TGAACAAGAAGCAAGCCTTAACCGACTTATGTGTGATATTTCAGAGCAAGTGATCGCAGTTGCAGATTCAACCAAATTTG
GTAAACGCAGCTGTCATATGATCAGAGAATTCGGAAATATTGATATCTTAGTTACTGATTCTGATATTCCTGAAGAGTAC
CTACAAGGTCTCCGTGAAATGAAAGTTGAAGTAATCATTGTCGAAAAAGAAAAGTAA

Upstream 100 bases:

>100_bases
AAAGTTTCATACTTCCATATTGTAGGAATAATTTTTAGGTGTAAGGTTAATTCGAAATCAAACGAAAGAGATTTCGTTGA
TTTAAGGAGACAAGTAAAAA

Downstream 100 bases:

>100_bases
CCGACCTAACTCCATAGCTGCATTCGGATGCAGTATGGAGTTAGTAAATGAACACCTTTCAACATCTTGTACAGCGTCAC
AAAGCGGGTGAGCAAAACGG

Product: DNA-binding transcriptional dual regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MMSAVERRMEIVNVVNQDGKARVEDLAARFDVSSVTIRSDLSFLEKNGYVVRSHGAAIPNTGVIAELTVHEKRHQNIGTK
SSIGYAAAQLIENGDTVILDSGTTTREIASNLKSLEQAVVMTNGLDVAMELASASGIEVLMSGGVLRKKALSFSGSQAEA
SLKNYRFDKVFLGVDGFDLRSGITTHNEQEASLNRLMCDISEQVIAVADSTKFGKRSCHMIREFGNIDILVTDSDIPEEY
LQGLREMKVEVIIVEKEK

Sequences:

>Translated_258_residues
MMSAVERRMEIVNVVNQDGKARVEDLAARFDVSSVTIRSDLSFLEKNGYVVRSHGAAIPNTGVIAELTVHEKRHQNIGTK
SSIGYAAAQLIENGDTVILDSGTTTREIASNLKSLEQAVVMTNGLDVAMELASASGIEVLMSGGVLRKKALSFSGSQAEA
SLKNYRFDKVFLGVDGFDLRSGITTHNEQEASLNRLMCDISEQVIAVADSTKFGKRSCHMIREFGNIDILVTDSDIPEEY
LQGLREMKVEVIIVEKEK
>Mature_258_residues
MMSAVERRMEIVNVVNQDGKARVEDLAARFDVSSVTIRSDLSFLEKNGYVVRSHGAAIPNTGVIAELTVHEKRHQNIGTK
SSIGYAAAQLIENGDTVILDSGTTTREIASNLKSLEQAVVMTNGLDVAMELASASGIEVLMSGGVLRKKALSFSGSQAEA
SLKNYRFDKVFLGVDGFDLRSGITTHNEQEASLNRLMCDISEQVIAVADSTKFGKRSCHMIREFGNIDILVTDSDIPEEY
LQGLREMKVEVIIVEKEK

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=251, Percent_Identity=48.605577689243, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI1789059, Length=253, Percent_Identity=36.3636363636364, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI226510968, Length=261, Percent_Identity=30.6513409961686, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1788069, Length=252, Percent_Identity=28.1746031746032, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789829, Length=251, Percent_Identity=27.8884462151394, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1787540, Length=249, Percent_Identity=27.710843373494, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082344, Length=252, Percent_Identity=25.7936507936508, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790753, Length=216, Percent_Identity=27.3148148148148, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787063, Length=247, Percent_Identity=21.8623481781377, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789170, Length=211, Percent_Identity=25.1184834123223, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790635, Length=261, Percent_Identity=25.2873563218391, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28199; Mature: 28199

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSAVERRMEIVNVVNQDGKARVEDLAARFDVSSVTIRSDLSFLEKNGYVVRSHGAAIPN
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHCCCEEEEECCCCCCC
TGVIAELTVHEKRHQNIGTKSSIGYAAAQLIENGDTVILDSGTTTREIASNLKSLEQAVV
CCEEEEEEEHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHH
MTNGLDVAMELASASGIEVLMSGGVLRKKALSFSGSQAEASLKNYRFDKVFLGVDGFDLR
HCCCHHHHHHHHCCCCHHEECCCCHHHHHHHCCCCCHHHHHHHHCCEEEEEEECCCCHHH
SGITTHNEQEASLNRLMCDISEQVIAVADSTKFGKRSCHMIREFGNIDILVTDSDIPEEY
CCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCHHH
LQGLREMKVEVIIVEKEK
HHHHHHCEEEEEEEECCC
>Mature Secondary Structure
MMSAVERRMEIVNVVNQDGKARVEDLAARFDVSSVTIRSDLSFLEKNGYVVRSHGAAIPN
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHCCCEEEEECCCCCCC
TGVIAELTVHEKRHQNIGTKSSIGYAAAQLIENGDTVILDSGTTTREIASNLKSLEQAVV
CCEEEEEEEHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHH
MTNGLDVAMELASASGIEVLMSGGVLRKKALSFSGSQAEASLKNYRFDKVFLGVDGFDLR
HCCCHHHHHHHHCCCCHHEECCCCHHHHHHHCCCCCHHHHHHHHCCEEEEEEECCCCHHH
SGITTHNEQEASLNRLMCDISEQVIAVADSTKFGKRSCHMIREFGNIDILVTDSDIPEEY
CCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCHHH
LQGLREMKVEVIIVEKEK
HHHHHHCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]