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The map label for this gene is nagA3 [H]

Identifier: 59714182

GI number: 59714182

Start: 1123482

End: 1124624

Strand: Reverse

Name: nagA3 [H]

Synonym: VF_A0999

Alternate gene names: 59714182

Gene position: 1124624-1123482 (Counterclockwise)

Preceding gene: 59714183

Following gene: 59714181

Centisome position: 84.54

GC content: 43.39

Gene sequence:

>1143_bases
ATGCGCTACGCTTTATATCCACAACGTGTGTTTGTTGCTGATGGCATTAAAGAACATCATTACGTCATAGTGAATGATGG
GAAAATAGAAGCAATAACAGCATGTGAACCAACAGATTGCGAGATTTTGCCATTAGAAGGAAAAACCTTGTTACCGGGGT
TTATCGACATTCATATCCATGGGCGAGCAGGCGCTGATGTTATGGACGCGACGCCAGAAGCATTGCAAACCATTTCTGAT
GCTTTGCTTCAAACAGGGGTTGTTGCTTGGGTTGGAACAACGGTAACGGCACCTTGGGATAGCATTGTTAGCTCAATCGA
TACTGTAAAAACGTGGTTAGATAAACCTCAACAGTGTGGTGCTGAGTTATTAGGTAGCTTTCTAGAAGGTCCATATTTTA
CAGAAGTGCATCGAGGCTCGCATCCAACCGCTTATTTAAAATCACCAAGCATTCAAGAGTTAGAAGAACTTTATGACGTA
GCGGCGCATTCACTATTACGAGTAGCGATAGCACCTGAAGCTGATGGTGCAATGGAAGCTATTCAATGGCTGCAAAGTCA
AAACATCAAAACCTCTGTCGCTCATACTGATTCAACGTTCGAGCAAGTTACCCAAGCACATCAATTAGGTGCCGATTGTG
GTGTCCATTTGTTTAATGGTATGCGTGGTTTACACCATAGAGAACCCGGCTGTACAGGGGCTGTTTTATATCATGACATG
CTTGCTGAATTAATTGCTGATAGTGTGCATGTTCATCCTGTAATGATGCAGCTCGCTTATCGCATGAAAGGGTATCAGCA
AATCGCACTTATTACGGACTGTATGCGAGCTGGTGGTTTAGAGGATGGTGAGTACCAACTTGGTGCGCAAACTATCACTG
TAGCTAAAGGGGAAGCGAGAACAAAATGTGGTTCGCTTGCTGGAAGCACATGCAGTTTAGATAGTGCGTTAAGAAATATG
ATTCAGCTAAGTGAAGTACCAGAATGGGAGGCGGTGCAAATGGCAACATTGGTTCCTGCCAAATATTTAGGCATTGATGA
TCGCTTAGGAAGCATTGCACCAGAAATGGAAGCAAGCTTTGTGGTGGTAAATCAAGATTTCGCTGTTCAGAACACCATGA
TTAAAGGTGAGTGGGTTTATTAA

Upstream 100 bases:

>100_bases
ACGACATTATTAGAAATAGGCTCTTCATGTATGCAAGACATGCGATTACAGCTTGAATTGTTCATGGAACCAGAACCTGA
ATGTGAAGATGGGTTGTAAT

Downstream 100 bases:

>100_bases
CTCTCGTCATTTTTATTAAAGATTCATAGCTATCTAAATAAACATCTAATAATGAATTATTTAGATAGCTATAACACAAA
ACAATGTTTTAGAGGTTTAA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MRYALYPQRVFVADGIKEHHYVIVNDGKIEAITACEPTDCEILPLEGKTLLPGFIDIHIHGRAGADVMDATPEALQTISD
ALLQTGVVAWVGTTVTAPWDSIVSSIDTVKTWLDKPQQCGAELLGSFLEGPYFTEVHRGSHPTAYLKSPSIQELEELYDV
AAHSLLRVAIAPEADGAMEAIQWLQSQNIKTSVAHTDSTFEQVTQAHQLGADCGVHLFNGMRGLHHREPGCTGAVLYHDM
LAELIADSVHVHPVMMQLAYRMKGYQQIALITDCMRAGGLEDGEYQLGAQTITVAKGEARTKCGSLAGSTCSLDSALRNM
IQLSEVPEWEAVQMATLVPAKYLGIDDRLGSIAPEMEASFVVVNQDFAVQNTMIKGEWVY

Sequences:

>Translated_380_residues
MRYALYPQRVFVADGIKEHHYVIVNDGKIEAITACEPTDCEILPLEGKTLLPGFIDIHIHGRAGADVMDATPEALQTISD
ALLQTGVVAWVGTTVTAPWDSIVSSIDTVKTWLDKPQQCGAELLGSFLEGPYFTEVHRGSHPTAYLKSPSIQELEELYDV
AAHSLLRVAIAPEADGAMEAIQWLQSQNIKTSVAHTDSTFEQVTQAHQLGADCGVHLFNGMRGLHHREPGCTGAVLYHDM
LAELIADSVHVHPVMMQLAYRMKGYQQIALITDCMRAGGLEDGEYQLGAQTITVAKGEARTKCGSLAGSTCSLDSALRNM
IQLSEVPEWEAVQMATLVPAKYLGIDDRLGSIAPEMEASFVVVNQDFAVQNTMIKGEWVY
>Mature_380_residues
MRYALYPQRVFVADGIKEHHYVIVNDGKIEAITACEPTDCEILPLEGKTLLPGFIDIHIHGRAGADVMDATPEALQTISD
ALLQTGVVAWVGTTVTAPWDSIVSSIDTVKTWLDKPQQCGAELLGSFLEGPYFTEVHRGSHPTAYLKSPSIQELEELYDV
AAHSLLRVAIAPEADGAMEAIQWLQSQNIKTSVAHTDSTFEQVTQAHQLGADCGVHLFNGMRGLHHREPGCTGAVLYHDM
LAELIADSVHVHPVMMQLAYRMKGYQQIALITDCMRAGGLEDGEYQLGAQTITVAKGEARTKCGSLAGSTCSLDSALRNM
IQLSEVPEWEAVQMATLVPAKYLGIDDRLGSIAPEMEASFVVVNQDFAVQNTMIKGEWVY

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=394, Percent_Identity=29.4416243654822, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI224922791, Length=390, Percent_Identity=29.2307692307692, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI1786892, Length=385, Percent_Identity=28.8311688311688, Blast_Score=168, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI17553768, Length=396, Percent_Identity=30.050505050505, Blast_Score=157, Evalue=9e-39,
Organism=Drosophila melanogaster, GI19920392, Length=354, Percent_Identity=30.7909604519774, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI281361140, Length=365, Percent_Identity=29.8630136986301, Blast_Score=144, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41451; Mature: 41451

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYALYPQRVFVADGIKEHHYVIVNDGKIEAITACEPTDCEILPLEGKTLLPGFIDIHIH
CCCCCCCCEEEEECCCCCCCEEEEECCCEEEEECCCCCCCEEEECCCCEECCCEEEEEEE
GRAGADVMDATPEALQTISDALLQTGVVAWVGTTVTAPWDSIVSSIDTVKTWLDKPQQCG
CCCCCCHHCCCHHHHHHHHHHHHHHCHHHEECCCCCCCHHHHHHHHHHHHHHHCCHHHHH
AELLGSFLEGPYFTEVHRGSHPTAYLKSPSIQELEELYDVAAHSLLRVAIAPEADGAMEA
HHHHHHHHCCCEEEHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHEEEECCCCCHHHHH
IQWLQSQNIKTSVAHTDSTFEQVTQAHQLGADCGVHLFNGMRGLHHREPGCTGAVLYHDM
HHHHHHCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LAELIADSVHVHPVMMQLAYRMKGYQQIALITDCMRAGGLEDGEYQLGAQTITVAKGEAR
HHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEECCEEEEEECCCHH
TKCGSLAGSTCSLDSALRNMIQLSEVPEWEAVQMATLVPAKYLGIDDRLGSIAPEMEASF
HHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHCCCCHHHHCCCCCCCCCE
VVVNQDFAVQNTMIKGEWVY
EEEECCCEEHHEEECCEECC
>Mature Secondary Structure
MRYALYPQRVFVADGIKEHHYVIVNDGKIEAITACEPTDCEILPLEGKTLLPGFIDIHIH
CCCCCCCCEEEEECCCCCCCEEEEECCCEEEEECCCCCCCEEEECCCCEECCCEEEEEEE
GRAGADVMDATPEALQTISDALLQTGVVAWVGTTVTAPWDSIVSSIDTVKTWLDKPQQCG
CCCCCCHHCCCHHHHHHHHHHHHHHCHHHEECCCCCCCHHHHHHHHHHHHHHHCCHHHHH
AELLGSFLEGPYFTEVHRGSHPTAYLKSPSIQELEELYDVAAHSLLRVAIAPEADGAMEA
HHHHHHHHCCCEEEHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHEEEECCCCCHHHHH
IQWLQSQNIKTSVAHTDSTFEQVTQAHQLGADCGVHLFNGMRGLHHREPGCTGAVLYHDM
HHHHHHCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LAELIADSVHVHPVMMQLAYRMKGYQQIALITDCMRAGGLEDGEYQLGAQTITVAKGEAR
HHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEECCEEEEEECCCHH
TKCGSLAGSTCSLDSALRNMIQLSEVPEWEAVQMATLVPAKYLGIDDRLGSIAPEMEASF
HHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHCCCCHHHHCCCCCCCCCE
VVVNQDFAVQNTMIKGEWVY
EEEECCCEEHHEEECCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969210 [H]