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The map label for this gene is gatY [H]

Identifier: 59714172

GI number: 59714172

Start: 1108505

End: 1109359

Strand: Reverse

Name: gatY [H]

Synonym: VF_A0989

Alternate gene names: 59714172

Gene position: 1109359-1108505 (Counterclockwise)

Preceding gene: 59714173

Following gene: 59714171

Centisome position: 83.39

GC content: 39.88

Gene sequence:

>855_bases
ATGTTTCTTGTATCATCCCGTGAAATGCTCCACAAAGCGCAGTTGGGTGGTTATGCCGTTCCTGCATTTAACATCCATAA
TTTAGAAACGGCTCAGGTCGTTGTTGAAACTGCTGCAGAAATGCAAACACCAGTTATTCTTGCTGGTACCCCCGGAACAT
TTTCTTATGCAGGAACTGATTACCTAATCGGTATTTGTAAAGAGGCCGCAAAACGTTACCACATGCCTATTGCACTGCAT
TTAGATCATCATGAATCGTATTCTGATATTCAGAAAAAAGTAGAAGCAGGAATTAAATCAGCAATGATTGATGGTTCTCA
TTTAAGTTTTGATAAAAACATCGATCTCGTCCGTAAAGTGGTTCAATTTTGTCACCGCTGGGACTGTTCAGTTGAAGCTG
AATTAGGTCGTTTAGGTGGACAAGAAGACGATTTAATCGTTGATGAAAAAGATGCTATGTATACGGATCCCGATGCGGCG
GTTGAATTTATTAAAGCGACGGGTATTGATTCTCTCGCCATTGCTATCGGTACTGCACATGGATTGTATAAAGAAAAACC
ATGTTTAGATTTTGACCGACTAGGCATTATTCGCGGTAAAACTGACGTACCTTTGGTATTACATGGTGCATCAGACGTGC
CTGATGAAGATGTACGTCGTTGTATTGAATTAGGTATTACCAAAGTAAATGTGGCAACAGAGCTAAAAATTGCTTTTTCA
GATGCAGTGAAATCTTACTTTATCGAAAATCCAGGTGCTAACGATCCTCGTCACTATATTATCCCTGGTAAAGAAGCGAT
GAAAAAAGTCGTTCAAGATAAAATTCGAGTGTGTGGCAGTGAAGGAAAGCTGTAA

Upstream 100 bases:

>100_bases
TTCGTTGATTTTTTGTTCTGTGATCTTGCTCATCTTATTTATGTTTTCTTTCGAATAATATAATAGCGAAAGTAAACGAA
GAATTTGACTTGAGGTTATT

Downstream 100 bases:

>100_bases
TACGAGTTTTGTTCCATTTTAGCCTTATATGGTTTTGCCGCATTGATTTAATCAAACCCTCTAATTGAATCAATGCGGCT
TTTTTTAGGTTATTGTATGA

Product: tagatose-bisphosphate aldolase

Products: NA

Alternate protein names: TBPA; TagBP aldolase; D-tagatose-bisphosphate aldolase class II; Tagatose-bisphosphate aldolase [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MFLVSSREMLHKAQLGGYAVPAFNIHNLETAQVVVETAAEMQTPVILAGTPGTFSYAGTDYLIGICKEAAKRYHMPIALH
LDHHESYSDIQKKVEAGIKSAMIDGSHLSFDKNIDLVRKVVQFCHRWDCSVEAELGRLGGQEDDLIVDEKDAMYTDPDAA
VEFIKATGIDSLAIAIGTAHGLYKEKPCLDFDRLGIIRGKTDVPLVLHGASDVPDEDVRRCIELGITKVNVATELKIAFS
DAVKSYFIENPGANDPRHYIIPGKEAMKKVVQDKIRVCGSEGKL

Sequences:

>Translated_284_residues
MFLVSSREMLHKAQLGGYAVPAFNIHNLETAQVVVETAAEMQTPVILAGTPGTFSYAGTDYLIGICKEAAKRYHMPIALH
LDHHESYSDIQKKVEAGIKSAMIDGSHLSFDKNIDLVRKVVQFCHRWDCSVEAELGRLGGQEDDLIVDEKDAMYTDPDAA
VEFIKATGIDSLAIAIGTAHGLYKEKPCLDFDRLGIIRGKTDVPLVLHGASDVPDEDVRRCIELGITKVNVATELKIAFS
DAVKSYFIENPGANDPRHYIIPGKEAMKKVVQDKIRVCGSEGKL
>Mature_284_residues
MFLVSSREMLHKAQLGGYAVPAFNIHNLETAQVVVETAAEMQTPVILAGTPGTFSYAGTDYLIGICKEAAKRYHMPIALH
LDHHESYSDIQKKVEAGIKSAMIDGSHLSFDKNIDLVRKVVQFCHRWDCSVEAELGRLGGQEDDLIVDEKDAMYTDPDAA
VEFIKATGIDSLAIAIGTAHGLYKEKPCLDFDRLGIIRGKTDVPLVLHGASDVPDEDVRRCIELGITKVNVATELKIAFS
DAVKSYFIENPGANDPRHYIIPGKEAMKKVVQDKIRVCGSEGKL

Specific function: Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6- bisphosphate (T

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase GatY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=284, Percent_Identity=61.2676056338028, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI87082041, Length=283, Percent_Identity=60.0706713780919, Blast_Score=363, Evalue=1e-102,
Organism=Escherichia coli, GI1788072, Length=269, Percent_Identity=37.546468401487, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1789293, Length=294, Percent_Identity=25.5102040816327, Blast_Score=86, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322790, Length=318, Percent_Identity=25.7861635220126, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000771
- InterPro:   IPR011288 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.40 [H]

Molecular weight: Translated: 31182; Mature: 31182

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLVSSREMLHKAQLGGYAVPAFNIHNLETAQVVVETAAEMQTPVILAGTPGTFSYAGTD
CEEECCHHHHHHHHCCCEECCEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHH
YLIGICKEAAKRYHMPIALHLDHHESYSDIQKKVEAGIKSAMIDGSHLSFDKNIDLVRKV
HHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHH
VQFCHRWDCSVEAELGRLGGQEDDLIVDEKDAMYTDPDAAVEFIKATGIDSLAIAIGTAH
HHHHHHCCCCEEHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHH
GLYKEKPCLDFDRLGIIRGKTDVPLVLHGASDVPDEDVRRCIELGITKVNVATELKIAFS
CCCCCCCCCCHHHCEEEECCCCCCEEEECCCCCCHHHHHHHHHHCCEEEEEEEEEEHHHH
DAVKSYFIENPGANDPRHYIIPGKEAMKKVVQDKIRVCGSEGKL
HHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFLVSSREMLHKAQLGGYAVPAFNIHNLETAQVVVETAAEMQTPVILAGTPGTFSYAGTD
CEEECCHHHHHHHHCCCEECCEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHH
YLIGICKEAAKRYHMPIALHLDHHESYSDIQKKVEAGIKSAMIDGSHLSFDKNIDLVRKV
HHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHH
VQFCHRWDCSVEAELGRLGGQEDDLIVDEKDAMYTDPDAAVEFIKATGIDSLAIAIGTAH
HHHHHHCCCCEEHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHH
GLYKEKPCLDFDRLGIIRGKTDVPLVLHGASDVPDEDVRRCIELGITKVNVATELKIAFS
CCCCCCCCCCHHHCEEEECCCCCCEEEECCCCCCHHHHHHHHHHCCEEEEEEEEEEHHHH
DAVKSYFIENPGANDPRHYIIPGKEAMKKVVQDKIRVCGSEGKL
HHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA