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The map label for this gene is fecD [H]

Identifier: 59714155

GI number: 59714155

Start: 1093406

End: 1094446

Strand: Reverse

Name: fecD [H]

Synonym: VF_A0972

Alternate gene names: 59714155

Gene position: 1094446-1093406 (Counterclockwise)

Preceding gene: 59714156

Following gene: 59714154

Centisome position: 82.27

GC content: 39.87

Gene sequence:

>1041_bases
ATGCCTTTTTATCGTTTAACCTCTTTTCAAGCTATTGTCTCTACGTGTTTATTTATTGGATTATTCTTAACATATTTAAG
TCTTGGTGCGGTTCACATTCCAATCATTGATATTTTAGCTATGTTTAAGAGTTATATATTTGGTGGGAGTGAGTTAGCAA
CTAAAGAGTATCCGCTTGCTTCTGCAATAGTGATGCACATTCGTTTGCCAAGGGCGTGTGCTGCAATTATGGCTGGTGGT
GCATTGGCTTTAGCTGGAGCCTGTACTCAAGGATTATTTAAAAACCCATTAGCGAGTCCTGATGTATTGGGGGTAAGCTC
GGGAAGCAGTTTTGGTGCTGTTATCGCTATTGTTACGGGTTTTTCTTTTATGAATCCGATGTGGTTACCTGTTTTTACAA
CGGTTGGTGCTCTTACTGCTTCTGCGTTTATTTATGTTCTTGCATCTCGTCACTCTTCTTCACAAATTTTATTTCTCATA
TTAACTGGATTGGCGCTATCGAGTTTATTGGGCGGTGCTCGTATGGGACTGCTATTAATGGCGCAACAGTATGAAGTCAG
CCAATTTGTTTTCTGGGCAATGGGGGGGCTAGATGGTCGTATGTGGCAGCATTTATTATGGCCAACACCTGTGATTATTA
TTGTGTCTACCTTGTTACTCAAAGAAAGCCGTTCTCTCAATTTACTCGCTTTAGGTGAGGAGAGTGCTCATGGTATGGGT
CTAAATGTAAAACAGACACGATTTAAATTATTGTTGTTTGCTACGTTATTAACGGCGATGTCGATTGCTATTGCTGGACC
TATTGGTTTTATCGGCTTGATGGTTCCTCATTTAGTGCGTCTATTAGTAGGACCAAGTCATGAGAAATTATTGCCGTTTT
CAGCCATATTTGGTGTGATATTTCTATTGGTTTGTGACTTATTAGGGCGTTGGATCATTGCGCCTAATGAATTGAAAGCG
GGGATTATTACTTCATTTATTGGTGGTTGCTACTTTATTGGCTTGATCATTCGATTTCAAAGAAAGGGACGTTTAGCATG
A

Upstream 100 bases:

>100_bases
GTCGGGTCTATCAAATGCCACATGTGTTAAGAAGTGTTTATAGCCAATATATTATTGATGCGATTCTGTTTGTTAATCAC
TCTGCCTATAAGAAACTCTG

Downstream 100 bases:

>100_bases
AACCATTATTAAATGTCTCACAATTAAACTATCAGGTTGGGACTAAAGCATTATTAAAGTCGATTTCATTTACCGTCAAT
TCTGGTGAATTGGTTGGTAT

Product: KpLE2 phage-like element; iron-dicitrate transporter subunit

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MPFYRLTSFQAIVSTCLFIGLFLTYLSLGAVHIPIIDILAMFKSYIFGGSELATKEYPLASAIVMHIRLPRACAAIMAGG
ALALAGACTQGLFKNPLASPDVLGVSSGSSFGAVIAIVTGFSFMNPMWLPVFTTVGALTASAFIYVLASRHSSSQILFLI
LTGLALSSLLGGARMGLLLMAQQYEVSQFVFWAMGGLDGRMWQHLLWPTPVIIIVSTLLLKESRSLNLLALGEESAHGMG
LNVKQTRFKLLLFATLLTAMSIAIAGPIGFIGLMVPHLVRLLVGPSHEKLLPFSAIFGVIFLLVCDLLGRWIIAPNELKA
GIITSFIGGCYFIGLIIRFQRKGRLA

Sequences:

>Translated_346_residues
MPFYRLTSFQAIVSTCLFIGLFLTYLSLGAVHIPIIDILAMFKSYIFGGSELATKEYPLASAIVMHIRLPRACAAIMAGG
ALALAGACTQGLFKNPLASPDVLGVSSGSSFGAVIAIVTGFSFMNPMWLPVFTTVGALTASAFIYVLASRHSSSQILFLI
LTGLALSSLLGGARMGLLLMAQQYEVSQFVFWAMGGLDGRMWQHLLWPTPVIIIVSTLLLKESRSLNLLALGEESAHGMG
LNVKQTRFKLLLFATLLTAMSIAIAGPIGFIGLMVPHLVRLLVGPSHEKLLPFSAIFGVIFLLVCDLLGRWIIAPNELKA
GIITSFIGGCYFIGLIIRFQRKGRLA
>Mature_345_residues
PFYRLTSFQAIVSTCLFIGLFLTYLSLGAVHIPIIDILAMFKSYIFGGSELATKEYPLASAIVMHIRLPRACAAIMAGGA
LALAGACTQGLFKNPLASPDVLGVSSGSSFGAVIAIVTGFSFMNPMWLPVFTTVGALTASAFIYVLASRHSSSQILFLIL
TGLALSSLLGGARMGLLLMAQQYEVSQFVFWAMGGLDGRMWQHLLWPTPVIIIVSTLLLKESRSLNLLALGEESAHGMGL
NVKQTRFKLLLFATLLTAMSIAIAGPIGFIGLMVPHLVRLLVGPSHEKLLPFSAIFGVIFLLVCDLLGRWIIAPNELKAG
IITSFIGGCYFIGLIIRFQRKGRLA

Specific function: Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=278, Percent_Identity=39.2086330935252, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI1788004, Length=285, Percent_Identity=36.140350877193, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786805, Length=286, Percent_Identity=40.9090909090909, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1790741, Length=293, Percent_Identity=32.7645051194539, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1786347, Length=290, Percent_Identity=35.5172413793103, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786804, Length=283, Percent_Identity=31.8021201413428, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37200; Mature: 37069

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFYRLTSFQAIVSTCLFIGLFLTYLSLGAVHIPIIDILAMFKSYIFGGSELATKEYPLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHCCCCCCHH
SAIVMHIRLPRACAAIMAGGALALAGACTQGLFKNPLASPDVLGVSSGSSFGAVIAIVTG
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHH
FSFMNPMWLPVFTTVGALTASAFIYVLASRHSSSQILFLILTGLALSSLLGGARMGLLLM
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AQQYEVSQFVFWAMGGLDGRMWQHLLWPTPVIIIVSTLLLKESRSLNLLALGEESAHGMG
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
LNVKQTRFKLLLFATLLTAMSIAIAGPIGFIGLMVPHLVRLLVGPSHEKLLPFSAIFGVI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
FLLVCDLLGRWIIAPNELKAGIITSFIGGCYFIGLIIRFQRKGRLA
HHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PFYRLTSFQAIVSTCLFIGLFLTYLSLGAVHIPIIDILAMFKSYIFGGSELATKEYPLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHCCCCCCHH
SAIVMHIRLPRACAAIMAGGALALAGACTQGLFKNPLASPDVLGVSSGSSFGAVIAIVTG
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHH
FSFMNPMWLPVFTTVGALTASAFIYVLASRHSSSQILFLILTGLALSSLLGGARMGLLLM
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AQQYEVSQFVFWAMGGLDGRMWQHLLWPTPVIIIVSTLLLKESRSLNLLALGEESAHGMG
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
LNVKQTRFKLLLFATLLTAMSIAIAGPIGFIGLMVPHLVRLLVGPSHEKLLPFSAIFGVI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
FLLVCDLLGRWIIAPNELKAGIITSFIGGCYFIGLIIRFQRKGRLA
HHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]