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The map label for this gene is rhtC [C]

Identifier: 59714121

GI number: 59714121

Start: 1059425

End: 1060039

Strand: Reverse

Name: rhtC [C]

Synonym: VF_A0938

Alternate gene names: 59714121

Gene position: 1060039-1059425 (Counterclockwise)

Preceding gene: 59714123

Following gene: 59714120

Centisome position: 79.68

GC content: 38.54

Gene sequence:

>615_bases
ATGACATTAACTATTTGGATTTCATTATTTTTGGTTTCATTGTTGGGAGCAATGTCTCCAGGACCAAGTTTAGCGACAGT
AGCGAAACATACCTTATCAGGTAAGCGAATTAATGGTATAGCAGCCGCTTGGGCTCATTCAATTGGTATTGGGTTTTATG
CTTTTATTACTGTGATTGGCTTAGTGGTAGTGTTACAACAGTCACCCGTGCTATTTAAAGGGATCAGCTATTTAGGTGCT
GCTTATTTGGCTTATTTAGGTCTCGGTGCCTTGCGTTCCACTGGCGGAATTGCAGCAAAGCTTGAATCTGGACAACAAGT
TACGATTGTTGAGTCAGCAAAAGAAGGGCTACTTATCTCACTTATAAACCCTAAAATTGCGTTGTTCTTTTTAGCTTTGT
TTAGTCAATTTGTCGCAGTAGGTAATGAACCTTTAGATAAAGCCATTATTGTTATCACACCTATTGTTGTTGATGGGCTG
TGGTATACGATTATTAGTTGTTTATTATCTGCCTCTAGAATTGTGGATAAACTCCGTAGTAAAGCGAAATGGATAGACAG
GTTATCTGGTGTCGTATTGATTTTATTAGCGATGCGAGTGGTTTTTTATAGCTAG

Upstream 100 bases:

>100_bases
AAAAGTGGTAGTAACCTTTTCATTATAAACTCGTCTATTTAACCGAATGTGCGATTTTATTGTGAATGAGACAATGTTGT
AAAGAGGAATTAAAGGCGAA

Downstream 100 bases:

>100_bases
TTTATCGGTTGGTTGTAATTAAAGAGGAAGTGCTTTTAAATTAAGAGTTCACTTTTTTCATCTCTCATTTTGGCTTACTA
TGACAATTCTCCACGTATAG

Product: threonine efflux protein

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MTLTIWISLFLVSLLGAMSPGPSLATVAKHTLSGKRINGIAAAWAHSIGIGFYAFITVIGLVVVLQQSPVLFKGISYLGA
AYLAYLGLGALRSTGGIAAKLESGQQVTIVESAKEGLLISLINPKIALFFLALFSQFVAVGNEPLDKAIIVITPIVVDGL
WYTIISCLLSASRIVDKLRSKAKWIDRLSGVVLILLAMRVVFYS

Sequences:

>Translated_204_residues
MTLTIWISLFLVSLLGAMSPGPSLATVAKHTLSGKRINGIAAAWAHSIGIGFYAFITVIGLVVVLQQSPVLFKGISYLGA
AYLAYLGLGALRSTGGIAAKLESGQQVTIVESAKEGLLISLINPKIALFFLALFSQFVAVGNEPLDKAIIVITPIVVDGL
WYTIISCLLSASRIVDKLRSKAKWIDRLSGVVLILLAMRVVFYS
>Mature_203_residues
TLTIWISLFLVSLLGAMSPGPSLATVAKHTLSGKRINGIAAAWAHSIGIGFYAFITVIGLVVVLQQSPVLFKGISYLGAA
YLAYLGLGALRSTGGIAAKLESGQQVTIVESAKEGLLISLINPKIALFFLALFSQFVAVGNEPLDKAIIVITPIVVDGLW
YTIISCLLSASRIVDKLRSKAKWIDRLSGVVLILLAMRVVFYS

Specific function: Conducts The Efflux Of Threonine. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=195, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788099, Length=188, Percent_Identity=30.8510638297872, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI48994979, Length=159, Percent_Identity=28.3018867924528, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21748; Mature: 21617

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: PS00902 GLUTAMATE_5_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTIWISLFLVSLLGAMSPGPSLATVAKHTLSGKRINGIAAAWAHSIGIGFYAFITVIG
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LVVVLQQSPVLFKGISYLGAAYLAYLGLGALRSTGGIAAKLESGQQVTIVESAKEGLLIS
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCCCCEEEE
LINPKIALFFLALFSQFVAVGNEPLDKAIIVITPIVVDGLWYTIISCLLSASRIVDKLRS
ECCHHHHHHHHHHHHHHHHHCCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAKWIDRLSGVVLILLAMRVVFYS
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLTIWISLFLVSLLGAMSPGPSLATVAKHTLSGKRINGIAAAWAHSIGIGFYAFITVIG
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LVVVLQQSPVLFKGISYLGAAYLAYLGLGALRSTGGIAAKLESGQQVTIVESAKEGLLIS
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCCCCEEEE
LINPKIALFFLALFSQFVAVGNEPLDKAIIVITPIVVDGLWYTIISCLLSASRIVDKLRS
ECCHHHHHHHHHHHHHHHHHCCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAKWIDRLSGVVLILLAMRVVFYS
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]