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The map label for this gene is yqaB [C]

Identifier: 59714120

GI number: 59714120

Start: 1058618

End: 1059271

Strand: Reverse

Name: yqaB [C]

Synonym: VF_A0937

Alternate gene names: 59714120

Gene position: 1059271-1058618 (Counterclockwise)

Preceding gene: 59714121

Following gene: 59714116

Centisome position: 79.62

GC content: 39.6

Gene sequence:

>654_bases
ATGACATTTAAAGCTGCAATTTTCGATATGGATGGACTACTTCTCGATACAGAAAGAGTGTGTATGTCCGTGTTTCAACA
AGCATGTGAAGCAGAGAATGTTCCATTTCTTGAAGATGTTTATCTGTCGGGGATTGGCTGTAACGCTAAACGTATTGAAG
AGCTTTTCCGTGCTGGCTATGGTCCTGATATCGATTACCCTGCTTTAAATAAAGCGTGGCGTATCCGTTATTTTTCTATA
GTTCAGAATCAAGCTATTCCTGTTAAAGAAGGCGTTATTGAGCTGTTAGAGTGGTTAAAAGCCAATAAGATCCCAATGGC
TGTTGCTACATCAACTCAAAATGATATCGCTATTAAGAAATTAGCATTAGCGGGTCTTGATGGTTATTTTGATGTACTTG
CTACGGGGTGTGAGGTTGAGAACAGTAAGCCACATCCAGAAATTTATTTTTTAGCAGCGGAACGTTTAGGTATTGCTCCT
GAAACGTGCTTAGCATTTGAAGATTCTAATAATGGAACTCGTGCGGCGGTTACCGCAACAATGATCACTTACCAAATCCC
TGATTTAGTACAACCAAGCCAAGATGTTATTGAACTTGGTCATCGTATTTTACCTTCTATGGTTGAGGTTTTAGCTGAAC
TAAAAGCTCGCTAA

Upstream 100 bases:

>100_bases
TTTTTCATCTCTCATTTTGGCTTACTATGACAATTCTCCACGTATAGTGAGTTATAGGTATACGTAACGTTTTTTTGCTA
TTCATACAGTAAGGTTTCTC

Downstream 100 bases:

>100_bases
GATTTTCAAGTCTTATTTAAATAAACGGCTCATTTAATAGATGAGCCGTTTTTATTTATGGTAATAACGTTTCTATTTTA
GGTTGGAGTAAGTTAATCCA

Product: phosphoglycolate phosphatase

Products: glycolate; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MTFKAAIFDMDGLLLDTERVCMSVFQQACEAENVPFLEDVYLSGIGCNAKRIEELFRAGYGPDIDYPALNKAWRIRYFSI
VQNQAIPVKEGVIELLEWLKANKIPMAVATSTQNDIAIKKLALAGLDGYFDVLATGCEVENSKPHPEIYFLAAERLGIAP
ETCLAFEDSNNGTRAAVTATMITYQIPDLVQPSQDVIELGHRILPSMVEVLAELKAR

Sequences:

>Translated_217_residues
MTFKAAIFDMDGLLLDTERVCMSVFQQACEAENVPFLEDVYLSGIGCNAKRIEELFRAGYGPDIDYPALNKAWRIRYFSI
VQNQAIPVKEGVIELLEWLKANKIPMAVATSTQNDIAIKKLALAGLDGYFDVLATGCEVENSKPHPEIYFLAAERLGIAP
ETCLAFEDSNNGTRAAVTATMITYQIPDLVQPSQDVIELGHRILPSMVEVLAELKAR
>Mature_216_residues
TFKAAIFDMDGLLLDTERVCMSVFQQACEAENVPFLEDVYLSGIGCNAKRIEELFRAGYGPDIDYPALNKAWRIRYFSIV
QNQAIPVKEGVIELLEWLKANKIPMAVATSTQNDIAIKKLALAGLDGYFDVLATGCEVENSKPHPEIYFLAAERLGIAPE
TCLAFEDSNNGTRAAVTATMITYQIPDLVQPSQDVIELGHRILPSMVEVLAELKAR

Specific function: Displays high phosphatase activity toward erythrose 4- phosphate, fructose 6-phosphate, 2-deoxyglucose 6-phosphate, and mannose 6-phosphate. May have a role in the intracellular metabolism of many phosphorylated carbohydrates [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily [H]

Homologues:

Organism=Homo sapiens, GI197382691, Length=192, Percent_Identity=31.25, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1789046, Length=181, Percent_Identity=29.8342541436464, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788021, Length=200, Percent_Identity=30.5, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789787, Length=198, Percent_Identity=28.7878787878788, Blast_Score=65, Evalue=3e-12,
Organism=Drosophila melanogaster, GI116008157, Length=215, Percent_Identity=33.4883720930233, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI17137324, Length=214, Percent_Identity=30.8411214953271, Blast_Score=84, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.3.18

Molecular weight: Translated: 24017; Mature: 23886

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFKAAIFDMDGLLLDTERVCMSVFQQACEAENVPFLEDVYLSGIGCNAKRIEELFRAGY
CCCEEEEECCCCEEECHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCC
GPDIDYPALNKAWRIRYFSIVQNQAIPVKEGVIELLEWLKANKIPMAVATSTQNDIAIKK
CCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHH
LALAGLDGYFDVLATGCEVENSKPHPEIYFLAAERLGIAPETCLAFEDSNNGTRAAVTAT
HHHHCCCHHHHHHHCCCCCCCCCCCCEEEEEEEHHCCCCCHHEEEEECCCCCCCHHEEEH
MITYQIPDLVQPSQDVIELGHRILPSMVEVLAELKAR
HHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TFKAAIFDMDGLLLDTERVCMSVFQQACEAENVPFLEDVYLSGIGCNAKRIEELFRAGY
CCEEEEECCCCEEECHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCC
GPDIDYPALNKAWRIRYFSIVQNQAIPVKEGVIELLEWLKANKIPMAVATSTQNDIAIKK
CCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHH
LALAGLDGYFDVLATGCEVENSKPHPEIYFLAAERLGIAPETCLAFEDSNNGTRAAVTAT
HHHHCCCHHHHHHHCCCCCCCCCCCCEEEEEEEHHCCCCCHHEEEEECCCCCCCHHEEEH
MITYQIPDLVQPSQDVIELGHRILPSMVEVLAELKAR
HHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-phosphoglycolate; H2O

Specific reaction: 2-phosphoglycolate + H2O = glycolate + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]