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The map label for this gene is leuO [H]

Identifier: 59714080

GI number: 59714080

Start: 1016754

End: 1017617

Strand: Reverse

Name: leuO [H]

Synonym: VF_A0897

Alternate gene names: 59714080

Gene position: 1017617-1016754 (Counterclockwise)

Preceding gene: 59714092

Following gene: 59714075

Centisome position: 76.49

GC content: 34.49

Gene sequence:

>864_bases
ATGGATTTAAATTTAGTCCGTACGTTTATGGCGGTATATCAGTGTCAATCGTATACAAAAGCATCTGAATTATTGATGTT
GACTCAACCTGCGGTGAGTGCTGCAATTAAACGTCTTGAATCTGAGATAGGTAAACAATTATTTATTAAGAAAGGTCGAG
GAATAGAAGCCACTTCAAAAGCTCATGCGTTAGCAACTAAGTTTCAATTCGCATTAGATACGATTAATGACGCGGTTAAT
GATAAAAATACATTATCTGTGTATTGTGCTGAAATTATTCTTCATTCATTGGTTGGTTTAGAACAAATTAATTTTGCAGA
ATCTCCACGAAGTCAATCAATGTTGTTTGAACACTTGAGAGAACAAAAAGTTGATTTAGTTTTAGACGTTGCGACAATGA
AAGATTCTGCTTTTGTTATTGAAGATGCTTATGTTGAACCTTTAGTTGTTGTGTGTGCAAAAAATCATCCTCGGATTCAA
GGAGAACTGACAAAAGTGGATTATTACAGAGAATCGCATGTGATTTATTCTGCTTTATGGCAGGGAATGAATGGATTTGA
ACAAATAGCGCAAGAACCTGTTGAAGAAAGGAATATTGCATTAACTGTATCTTCGTTATCAAGTGTGCTTATGTTTGTCT
CGCAGGGGGATTCTTTAGGTTTAGTTTCTCAATCATTTGCAAAGCGGTGGGAAAAACAACTGAATTTAGCGATTTATCCG
TGTCCTGTTAAATTAGATAATGCTAAGTATAAGTTTATATATCACAAGCGTTACATTAATGACCCACAGCATAGAAAAGT
AAGACAGCAGATTATTGACAAATTGAGTAAGAAAAAACCATTTATGGAATGGATGGGGTTATAA

Upstream 100 bases:

>100_bases
GTGGTGATAAATAAGGTGAACTTACGCTGTTACCAAAATTCAATTTATGGATGGGTGTTTTTTGACTGTTTTTTTAACCC
TAAGTGAGTATTAGTAAGTC

Downstream 100 bases:

>100_bases
AAAAGCCCCTCCGCTCGAGAGAGTTGAGCAGAAGGGCAAAACGAAAGTATTTATAGTGAATAGAAGAAGTAAATTTGTGA
TTTCATACGAATGATGATGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MDLNLVRTFMAVYQCQSYTKASELLMLTQPAVSAAIKRLESEIGKQLFIKKGRGIEATSKAHALATKFQFALDTINDAVN
DKNTLSVYCAEIILHSLVGLEQINFAESPRSQSMLFEHLREQKVDLVLDVATMKDSAFVIEDAYVEPLVVVCAKNHPRIQ
GELTKVDYYRESHVIYSALWQGMNGFEQIAQEPVEERNIALTVSSLSSVLMFVSQGDSLGLVSQSFAKRWEKQLNLAIYP
CPVKLDNAKYKFIYHKRYINDPQHRKVRQQIIDKLSKKKPFMEWMGL

Sequences:

>Translated_287_residues
MDLNLVRTFMAVYQCQSYTKASELLMLTQPAVSAAIKRLESEIGKQLFIKKGRGIEATSKAHALATKFQFALDTINDAVN
DKNTLSVYCAEIILHSLVGLEQINFAESPRSQSMLFEHLREQKVDLVLDVATMKDSAFVIEDAYVEPLVVVCAKNHPRIQ
GELTKVDYYRESHVIYSALWQGMNGFEQIAQEPVEERNIALTVSSLSSVLMFVSQGDSLGLVSQSFAKRWEKQLNLAIYP
CPVKLDNAKYKFIYHKRYINDPQHRKVRQQIIDKLSKKKPFMEWMGL
>Mature_287_residues
MDLNLVRTFMAVYQCQSYTKASELLMLTQPAVSAAIKRLESEIGKQLFIKKGRGIEATSKAHALATKFQFALDTINDAVN
DKNTLSVYCAEIILHSLVGLEQINFAESPRSQSMLFEHLREQKVDLVLDVATMKDSAFVIEDAYVEPLVVVCAKNHPRIQ
GELTKVDYYRESHVIYSALWQGMNGFEQIAQEPVEERNIALTVSSLSSVLMFVSQGDSLGLVSQSFAKRWEKQLNLAIYP
CPVKLDNAKYKFIYHKRYINDPQHRKVRQQIIDKLSKKKPFMEWMGL

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=290, Percent_Identity=28.2758620689655, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI87081766, Length=278, Percent_Identity=23.021582733813, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786820, Length=296, Percent_Identity=25.3378378378378, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32742; Mature: 32742

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNLVRTFMAVYQCQSYTKASELLMLTQPAVSAAIKRLESEIGKQLFIKKGRGIEATSK
CCHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
AHALATKFQFALDTINDAVNDKNTLSVYCAEIILHSLVGLEQINFAESPRSQSMLFEHLR
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
EQKVDLVLDVATMKDSAFVIEDAYVEPLVVVCAKNHPRIQGELTKVDYYRESHVIYSALW
HCCHHHEEEEECCCCCEEEEEHHHHCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHH
QGMNGFEQIAQEPVEERNIALTVSSLSSVLMFVSQGDSLGLVSQSFAKRWEKQLNLAIYP
HCCCHHHHHHHCCHHHCCEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEE
CPVKLDNAKYKFIYHKRYINDPQHRKVRQQIIDKLSKKKPFMEWMGL
CCEEECCCEEEEEEEHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure
MDLNLVRTFMAVYQCQSYTKASELLMLTQPAVSAAIKRLESEIGKQLFIKKGRGIEATSK
CCHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
AHALATKFQFALDTINDAVNDKNTLSVYCAEIILHSLVGLEQINFAESPRSQSMLFEHLR
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
EQKVDLVLDVATMKDSAFVIEDAYVEPLVVVCAKNHPRIQGELTKVDYYRESHVIYSALW
HCCHHHEEEEECCCCCEEEEEHHHHCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHH
QGMNGFEQIAQEPVEERNIALTVSSLSSVLMFVSQGDSLGLVSQSFAKRWEKQLNLAIYP
HCCCHHHHHHHCCHHHCCEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEE
CPVKLDNAKYKFIYHKRYINDPQHRKVRQQIIDKLSKKKPFMEWMGL
CCEEECCCEEEEEEEHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3413113; 1630901; 9278503; 3519576 [H]