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The map label for this gene is bcsB [H]

Identifier: 59714066

GI number: 59714066

Start: 997602

End: 999896

Strand: Reverse

Name: bcsB [H]

Synonym: VF_A0883

Alternate gene names: 59714066

Gene position: 999896-997602 (Counterclockwise)

Preceding gene: 59714067

Following gene: 59714065

Centisome position: 75.16

GC content: 37.65

Gene sequence:

>2295_bases
ATGTCGATTAAAACAAAAATAAGCGTTTTTGCAGTAGCAATAGGTCTTATGAGCTCGGGTGTAAATGCATCGGTGGCTAC
AGCTCATAGTGACAATGCTCCATTACAAAATGGAATAATACAAACATCACAAGCATCCTCAATTATTACGAAAAAAACGT
TTAGTTTTGGTGATCTTGGTTATGGAGAATCAATCCGATTGCAGGGGAGTGAAAGTACCGCTTATATTGGTTTTGGCTCA
CGTTTAGATGAGGTTGTGTCTAAAGCCTCTCTTCATTTTGATTTTACGCCATCACCAGCATTGCTTTCTATGGTTTCACA
TATAAAGGTGTATTTTAATAACCAATTGGCTGGGGTTGTTGCTATTTCTGATGGTATGCAAGGTCAGAAAGGGGATGTTG
ATCTTGAGCTCGATCCGCGTTTGTTCACTGATTTTAACCAACTAAAATTTGAATTGGTTGGTAATGCCTCTATGTCATGT
AGTAATCCAAATGATAACAGTATTTGGACTGAAATCAGCTCTCAAAGTACGATTACATTAGCGACTCAAAAAACAAAAAT
TAATAACGATCTAAGTTTATTACCAGCGCCATTTTTTGATTCAAGAGACATGAAGCATGTCAATTTACCAATGGTATTTG
GTGAGAAGCTTGATCTTAATGAAATTAAAGCTGCGGGTATTGCTTCATCTTATTTTGGTGCGTTAGCTCAATGGCGTGGA
GCAAGTTTTCCAATATTAGATGATCAATTGCCAAAAAATGATGCGATTGTTTTTATCACTAATGATAGCAAACCTGATTT
TTTACGTGATTTCCCTGACGCTGATGGTCCTCGTATTCAAATGATTTCTCATCCAGCAGATCCTTACGTTAAATTATTGC
TGATTATGGGACGAGATAGTGAAGATTTAATTACTGCCGTGAAAGGACTAGCTTTAGGGCAAGATCTACTTACAGGACCA
TCGGCAAAAATTAATTCTGCAGAGCAATTAGTTCCTCGTATTCCTTATGACGCGCCCAATTGGATAAATACAGACAGACC
TGTTGCGTTATCAGAACTATTAACTGAAGGCATGACATTACAAGTGGAAGGGCAAAATCCGCCACCTATTTCTCTTCACT
TTAGATTGCCGCCTGATTTATTTACTTGGCAAAGTAACGGGATCCCATTTGACTTAAATTATCGTTATACGCCACCACTA
AGAGATCACTCTGGCTCTAGAATGAGTCTTAGTGTTAACAATCAATTTGTAAAAGCGTTTAATTTAAATACGTCAGGTGA
ATCAAATGATAATACCCACTTGAGACTTCCTTTGCTAGACGATGATTTATTAGGGAATGGTCAAGTGGTTCGTATTCCTG
CTTTCCAAGTGGGCAGTAAAAATGAAGTTAAATTTGAATTTGGTTTCGCTTCTTCTGTTGGTGGTAAAGATCAGTGTCAA
ACCATGCAACCAAGTAAGAATTATGCGGTAATCAATTCAGATTCGACCATCGATTTTTCAGGTTTCTCTCATTATATAGA
AATGCCGAACATGCGTGCTTTTGCTAATTCGGGCTATCCATTTACACGAATGGCTGATTTATCTGAAACGGTTGTTGTAT
TACCTAAGCAGCCAAGTACAGAAGAAATCCAGACTTTCGTTAATATGATGGGGGTATTTGGTTCTCATACTGGTTACTCA
GTATTAAATGTCGCTTTAACTGATAATTGGAATGAAAGTGACCTTGAAGATAAAGATATCTTAACCATAGGAATGACGCC
AGAGTTAGCGTCTATTAATAAAGAGAAAATTGAAAATATTCAATTAGTTGCATCGAATCGTATTGTTCAGTTACCAAGCA
AGAATGAGACTCAAAAAGGACAAAATTGGGGAGCTTCGTCAGGTAAAAACCAACAGGTTTCTGATTCAGTAAGTATTAAT
ACGACAGGTAACTTTGCGGCTATCACCAGTATGGAGTCACCATATACATCACAACGTACCATTGTGAGCGTTTTAGCACA
GACACCAGAATCATTTGCATTGGTCAATGAAGCATTAAATGACAGCGGCAAAGTGTCGGCTATGTTTGGTTCTGTTATTA
CCTTACGAGATGATGAGGTAGCCAGTTTTAATGTAGGAGAACATTACTACGTAGGTGAATTACCGATTTCTCAGTTGATT
TGGTACCACTTTTCAAAACACCCGTTAGTGATGGCTTTGCTTGCCGCCTTATTAGTTGTAATGGTCACAATTATTTTATT
TAGAGTACTTCGCCGTATCGCCAAAAATCGTTTAAACACAGAGGAAGATGAATAA

Upstream 100 bases:

>100_bases
CCTAAAACAGTGCGAGCTATCGTAAAACTAATAACTATAACAAGTGAGTTCTTACTCACATTTAAACCAAAAAAAGTCAA
TTTTTAGAGTGCAATCAGTT

Downstream 100 bases:

>100_bases
TGAAAATGCAATTAACGGTATTGAGTCTATTAATTGGCACGTTAACTTGCTCTTCTTCAGCTATTGCTCAAGATGAAAAT
TACACAACCCCAATCGTTTC

Product: cellulose synthase regulator protein

Products: UDP; (1,4-beta-D-glucosyl)n+1

Alternate protein names: Cellulose synthase regulatory subunit [H]

Number of amino acids: Translated: 764; Mature: 763

Protein sequence:

>764_residues
MSIKTKISVFAVAIGLMSSGVNASVATAHSDNAPLQNGIIQTSQASSIITKKTFSFGDLGYGESIRLQGSESTAYIGFGS
RLDEVVSKASLHFDFTPSPALLSMVSHIKVYFNNQLAGVVAISDGMQGQKGDVDLELDPRLFTDFNQLKFELVGNASMSC
SNPNDNSIWTEISSQSTITLATQKTKINNDLSLLPAPFFDSRDMKHVNLPMVFGEKLDLNEIKAAGIASSYFGALAQWRG
ASFPILDDQLPKNDAIVFITNDSKPDFLRDFPDADGPRIQMISHPADPYVKLLLIMGRDSEDLITAVKGLALGQDLLTGP
SAKINSAEQLVPRIPYDAPNWINTDRPVALSELLTEGMTLQVEGQNPPPISLHFRLPPDLFTWQSNGIPFDLNYRYTPPL
RDHSGSRMSLSVNNQFVKAFNLNTSGESNDNTHLRLPLLDDDLLGNGQVVRIPAFQVGSKNEVKFEFGFASSVGGKDQCQ
TMQPSKNYAVINSDSTIDFSGFSHYIEMPNMRAFANSGYPFTRMADLSETVVVLPKQPSTEEIQTFVNMMGVFGSHTGYS
VLNVALTDNWNESDLEDKDILTIGMTPELASINKEKIENIQLVASNRIVQLPSKNETQKGQNWGASSGKNQQVSDSVSIN
TTGNFAAITSMESPYTSQRTIVSVLAQTPESFALVNEALNDSGKVSAMFGSVITLRDDEVASFNVGEHYYVGELPISQLI
WYHFSKHPLVMALLAALLVVMVTIILFRVLRRIAKNRLNTEEDE

Sequences:

>Translated_764_residues
MSIKTKISVFAVAIGLMSSGVNASVATAHSDNAPLQNGIIQTSQASSIITKKTFSFGDLGYGESIRLQGSESTAYIGFGS
RLDEVVSKASLHFDFTPSPALLSMVSHIKVYFNNQLAGVVAISDGMQGQKGDVDLELDPRLFTDFNQLKFELVGNASMSC
SNPNDNSIWTEISSQSTITLATQKTKINNDLSLLPAPFFDSRDMKHVNLPMVFGEKLDLNEIKAAGIASSYFGALAQWRG
ASFPILDDQLPKNDAIVFITNDSKPDFLRDFPDADGPRIQMISHPADPYVKLLLIMGRDSEDLITAVKGLALGQDLLTGP
SAKINSAEQLVPRIPYDAPNWINTDRPVALSELLTEGMTLQVEGQNPPPISLHFRLPPDLFTWQSNGIPFDLNYRYTPPL
RDHSGSRMSLSVNNQFVKAFNLNTSGESNDNTHLRLPLLDDDLLGNGQVVRIPAFQVGSKNEVKFEFGFASSVGGKDQCQ
TMQPSKNYAVINSDSTIDFSGFSHYIEMPNMRAFANSGYPFTRMADLSETVVVLPKQPSTEEIQTFVNMMGVFGSHTGYS
VLNVALTDNWNESDLEDKDILTIGMTPELASINKEKIENIQLVASNRIVQLPSKNETQKGQNWGASSGKNQQVSDSVSIN
TTGNFAAITSMESPYTSQRTIVSVLAQTPESFALVNEALNDSGKVSAMFGSVITLRDDEVASFNVGEHYYVGELPISQLI
WYHFSKHPLVMALLAALLVVMVTIILFRVLRRIAKNRLNTEEDE
>Mature_763_residues
SIKTKISVFAVAIGLMSSGVNASVATAHSDNAPLQNGIIQTSQASSIITKKTFSFGDLGYGESIRLQGSESTAYIGFGSR
LDEVVSKASLHFDFTPSPALLSMVSHIKVYFNNQLAGVVAISDGMQGQKGDVDLELDPRLFTDFNQLKFELVGNASMSCS
NPNDNSIWTEISSQSTITLATQKTKINNDLSLLPAPFFDSRDMKHVNLPMVFGEKLDLNEIKAAGIASSYFGALAQWRGA
SFPILDDQLPKNDAIVFITNDSKPDFLRDFPDADGPRIQMISHPADPYVKLLLIMGRDSEDLITAVKGLALGQDLLTGPS
AKINSAEQLVPRIPYDAPNWINTDRPVALSELLTEGMTLQVEGQNPPPISLHFRLPPDLFTWQSNGIPFDLNYRYTPPLR
DHSGSRMSLSVNNQFVKAFNLNTSGESNDNTHLRLPLLDDDLLGNGQVVRIPAFQVGSKNEVKFEFGFASSVGGKDQCQT
MQPSKNYAVINSDSTIDFSGFSHYIEMPNMRAFANSGYPFTRMADLSETVVVLPKQPSTEEIQTFVNMMGVFGSHTGYSV
LNVALTDNWNESDLEDKDILTIGMTPELASINKEKIENIQLVASNRIVQLPSKNETQKGQNWGASSGKNQQVSDSVSINT
TGNFAAITSMESPYTSQRTIVSVLAQTPESFALVNEALNDSGKVSAMFGSVITLRDDEVASFNVGEHYYVGELPISQLIW
YHFSKHPLVMALLAALLVVMVTIILFRVLRRIAKNRLNTEEDE

Specific function: Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass type I membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AcsB/BcsB family [H]

Homologues:

Organism=Escherichia coli, GI1789952, Length=687, Percent_Identity=41.0480349344978, Blast_Score=575, Evalue=1e-165,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003920
- InterPro:   IPR018513 [H]

Pfam domain/function: PF03170 BcsB [H]

EC number: 2.4.1.12

Molecular weight: Translated: 83747; Mature: 83615

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKTKISVFAVAIGLMSSGVNASVATAHSDNAPLQNGIIQTSQASSIITKKTFSFGDLG
CCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHCCEEECCCCCHHHEECCCCCCCCC
YGESIRLQGSESTAYIGFGSRLDEVVSKASLHFDFTPSPALLSMVSHIKVYFNNQLAGVV
CCCEEEEECCCCEEEEECCHHHHHHHHHHEEEEECCCCHHHHHHHHHEEEEECCCEEEEE
AISDGMQGQKGDVDLELDPRLFTDFNQLKFELVGNASMSCSNPNDNSIWTEISSQSTITL
EEECCCCCCCCCEEEEECCHHHCCCCCEEEEEECCCEEECCCCCCCCEEEEECCCCEEEE
ATQKTKINNDLSLLPAPFFDSRDMKHVNLPMVFGEKLDLNEIKAAGIASSYFGALAQWRG
EEECEECCCCCEEECCCCCCCCCCEEECCCEEECCCCCHHHHHHHCCHHHHHHHHHHHCC
ASFPILDDQLPKNDAIVFITNDSKPDFLRDFPDADGPRIQMISHPADPYVKLLLIMGRDS
CCCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCCCCCEEEEEECCCCCCEEEEEEECCCC
EDLITAVKGLALGQDLLTGPSAKINSAEQLVPRIPYDAPNWINTDRPVALSELLTEGMTL
HHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCEE
QVEGQNPPPISLHFRLPPDLFTWQSNGIPFDLNYRYTPPLRDHSGSRMSLSVNNQFVKAF
EECCCCCCCEEEEEECCCCEEEECCCCCEEEECCEECCCCCCCCCCEEEEEECCEEEEEE
NLNTSGESNDNTHLRLPLLDDDLLGNGQVVRIPAFQVGSKNEVKFEFGFASSVGGKDQCQ
ECCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCEEEEEECCCCCCCCCHHC
TMQPSKNYAVINSDSTIDFSGFSHYIEMPNMRAFANSGYPFTRMADLSETVVVLPKQPST
CCCCCCCEEEEECCCEEEECCCHHEEECCCCEEECCCCCCCEEECCCCCEEEEECCCCCH
EEIQTFVNMMGVFGSHTGYSVLNVALTDNWNESDLEDKDILTIGMTPELASINKEKIENI
HHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCEEEEECCCCHHHCCHHHHCCE
QLVASNRIVQLPSKNETQKGQNWGASSGKNQQVSDSVSINTTGNFAAITSMESPYTSQRT
EEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCHHHH
IVSVLAQTPESFALVNEALNDSGKVSAMFGSVITLRDDEVASFNVGEHYYVGELPISQLI
HHHHHHHCCHHHHHHHHHHCCCCCEEEEECCEEEEECCCEEEEECCCEEEECCCCHHHHH
WYHFSKHPLVMALLAALLVVMVTIILFRVLRRIAKNRLNTEEDE
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SIKTKISVFAVAIGLMSSGVNASVATAHSDNAPLQNGIIQTSQASSIITKKTFSFGDLG
CCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHCCEEECCCCCHHHEECCCCCCCCC
YGESIRLQGSESTAYIGFGSRLDEVVSKASLHFDFTPSPALLSMVSHIKVYFNNQLAGVV
CCCEEEEECCCCEEEEECCHHHHHHHHHHEEEEECCCCHHHHHHHHHEEEEECCCEEEEE
AISDGMQGQKGDVDLELDPRLFTDFNQLKFELVGNASMSCSNPNDNSIWTEISSQSTITL
EEECCCCCCCCCEEEEECCHHHCCCCCEEEEEECCCEEECCCCCCCCEEEEECCCCEEEE
ATQKTKINNDLSLLPAPFFDSRDMKHVNLPMVFGEKLDLNEIKAAGIASSYFGALAQWRG
EEECEECCCCCEEECCCCCCCCCCEEECCCEEECCCCCHHHHHHHCCHHHHHHHHHHHCC
ASFPILDDQLPKNDAIVFITNDSKPDFLRDFPDADGPRIQMISHPADPYVKLLLIMGRDS
CCCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCCCCCEEEEEECCCCCCEEEEEEECCCC
EDLITAVKGLALGQDLLTGPSAKINSAEQLVPRIPYDAPNWINTDRPVALSELLTEGMTL
HHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCEE
QVEGQNPPPISLHFRLPPDLFTWQSNGIPFDLNYRYTPPLRDHSGSRMSLSVNNQFVKAF
EECCCCCCCEEEEEECCCCEEEECCCCCEEEECCEECCCCCCCCCCEEEEEECCEEEEEE
NLNTSGESNDNTHLRLPLLDDDLLGNGQVVRIPAFQVGSKNEVKFEFGFASSVGGKDQCQ
ECCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCEEEEEECCCCCCCCCHHC
TMQPSKNYAVINSDSTIDFSGFSHYIEMPNMRAFANSGYPFTRMADLSETVVVLPKQPST
CCCCCCCEEEEECCCEEEECCCHHEEECCCCEEECCCCCCCEEECCCCCEEEEECCCCCH
EEIQTFVNMMGVFGSHTGYSVLNVALTDNWNESDLEDKDILTIGMTPELASINKEKIENI
HHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCEEEEECCCCHHHCCHHHHCCE
QLVASNRIVQLPSKNETQKGQNWGASSGKNQQVSDSVSINTTGNFAAITSMESPYTSQRT
EEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCHHHH
IVSVLAQTPESFALVNEALNDSGKVSAMFGSVITLRDDEVASFNVGEHYYVGELPISQLI
HHHHHHHCCHHHHHHHHHHCCCCCEEEEECCEEEEECCCEEEEECCCEEEECCCCHHHHH
WYHFSKHPLVMALLAALLVVMVTIILFRVLRRIAKNRLNTEEDE
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-glucose; (1,4-beta-D-glucosyl)n

Specific reaction: UDP-glucose + (1,4-beta-D-glucosyl)n = UDP + (1,4-beta-D-glucosyl)n+1

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]