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The map label for this gene is tcpI [H]

Identifier: 59714042

GI number: 59714042

Start: 966976

End: 968850

Strand: Reverse

Name: tcpI [H]

Synonym: VF_A0859

Alternate gene names: 59714042

Gene position: 968850-966976 (Counterclockwise)

Preceding gene: 59714048

Following gene: 172087818

Centisome position: 72.83

GC content: 36.43

Gene sequence:

>1875_bases
ATGTTGTTAAAGAATAAAATATTATTATTTATATTCGTGTTATTGGTTTCGATAGCGAGTGCTTTAACTTGGAATGGTTT
TAATGAATTCAGTCAAATAAATAAAGATCTGATAACTAAATCGACGGAAGATCGATCTAAATTAATATCGGTATCGTTAG
GAGAAAAACTTGATGGCTACTTTTCATCATTGAGGACATTTTCTATATCTTATCACCCTGATGGTAGACTAGATGAAGTC
ACCACAACAAAGGATTTGAGAAAATTAGCAGAAAATAATGATACCAATAGTGCCTTTATCGCATTTGAGTCAGGACTTAC
TTTTGAAAATGGCCAGTTTATTCCTAACTTTAATGCTAAGGAGGTAAAACGCGAATGGTTTGTACGTGGCTTTGCTGGTG
AAAAGGAGATCATCACTGATGTGTATCAAAATACGGATGGAGTAAATGTATTTGCATTTGCAGTACCTATTTTAAGTGAT
GGTAAGGTTGTCGCTGTTGTGGCTATAGGGATTGAGCAGAATGTTTTAAATGCGTTTATTGGGACGCTCACAGAGCGAGG
ACAGATATTTACCTATAATAATTTAGGCTATATCATTGCTGCGAAAAATCCTGATGACGTTAGTAAGAACATAAAAAATG
TTGAACCTGAATTAGTCGATTTTGATTCTGGCAATACTCGTTTTTATGACATTGACCACGATGATTATGTTCTGGCAAGT
GCTGATAATTTATCTCGTTATGATTGGACGGTTGTCATGTATGAATACGAGGATGACGTTTACGCTCCTAGTATGGTGAT
GTTAAAGAATTCAATTATCATCTTCTTTTCACTTCTTATTATCTCATTAGCGATTGTTTATTATGGTGTTATCTATTTAA
TCTATAAACCAATTGGCGGAGAACCAGAGAACATCTCTGAAATTCTATCTAATATTTCGGAAGGTGATTTATCTCAGCAA
TTAGTGGCATCAGATAATGATACAGGTATATACCGTTCAGTGGTTACCTTAAGCTCGAAGTTGTCAGAAATAGTGACATC
AAGCCATTCAATTTCAAATAGTGTATCAGCAGCTTCAGAAGAGCTGGCTGTCGTCATGTCTGATACTGCTAAGAACTCAC
AGCATGAATTGGCACAAGTTGAAGAAATTTCTACTGCGATCAGTGAGCTATCGAGTACTTCAAAAGAAGTGACAACAAAT
GCCGCTCAGGCGGAAGAAGAAGCACAAAAAGCAATAACAAATGTATCAAATGGACATAATACACTTGATAATTCGATCGC
ATTGACTGTTGATATTAATGAATCTGTACAACAAACCGCAGAAATGATCTCTGTATTACGTGATGATGCAATTAATATTG
GTGAAGTGACGGACGTTATCAGCAGTATTTCAGAGCAAACGAACTTACTCGCATTAAATGCAGCAATTGAGGCTGCACGT
GCCGGTGAAGCGGGAAGAGGTTTTGCCGTGGTAGCTGATGAGGTTCGTAATCTAGCAGCTAAAACAAAGGAATCTACGAG
TAATATTCAGGAGATTATTAGCAAGCTACAGGCTCAGTCTGAAAATGCAAATAAAAATATGATGGAAAATGTCACATCTA
TTCAAGAATCGGTGCATCTTATTGAAAGTGTGAAAACATCATTTAATGATATCGTCAGCTCAGTTCAATCGATTTCTGAT
ATCAACACGTTAGTCGCAACAGCTTCACAAGAGCAATTCAGTGTGACGGAAGATATTGCTAAAAATACAACAAGAACGTT
TGATTTGGTAACACAAAATGTATCAGCGATTAATCAGACTCAGCAAGCTGCGGATGAGTTATCGAAATTAGCGGTAGCAC
AAAAAACCGAACTCGATTTCTTTAAGATGAATTGA

Upstream 100 bases:

>100_bases
GGTATTGATATAAACTATCAATAACTGGTTTTGTATTGATATTAGTTAATTAATGTAAGGTGAGTTTTTATATTAAAATA
GTGAACAAAAGGGATAATGG

Downstream 100 bases:

>100_bases
TTATCTTTATGAGACGATAAAAAAATAGCCTTTAGTGAAAGCTAAAGGCTATTTTTGATTAAAGGATATATTTAAGCCGC
TTTTCTGTTTTCTTATCTTT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: TCP pilus biosynthesis protein tcpI [H]

Number of amino acids: Translated: 624; Mature: 624

Protein sequence:

>624_residues
MLLKNKILLFIFVLLVSIASALTWNGFNEFSQINKDLITKSTEDRSKLISVSLGEKLDGYFSSLRTFSISYHPDGRLDEV
TTTKDLRKLAENNDTNSAFIAFESGLTFENGQFIPNFNAKEVKREWFVRGFAGEKEIITDVYQNTDGVNVFAFAVPILSD
GKVVAVVAIGIEQNVLNAFIGTLTERGQIFTYNNLGYIIAAKNPDDVSKNIKNVEPELVDFDSGNTRFYDIDHDDYVLAS
ADNLSRYDWTVVMYEYEDDVYAPSMVMLKNSIIIFFSLLIISLAIVYYGVIYLIYKPIGGEPENISEILSNISEGDLSQQ
LVASDNDTGIYRSVVTLSSKLSEIVTSSHSISNSVSAASEELAVVMSDTAKNSQHELAQVEEISTAISELSSTSKEVTTN
AAQAEEEAQKAITNVSNGHNTLDNSIALTVDINESVQQTAEMISVLRDDAINIGEVTDVISSISEQTNLLALNAAIEAAR
AGEAGRGFAVVADEVRNLAAKTKESTSNIQEIISKLQAQSENANKNMMENVTSIQESVHLIESVKTSFNDIVSSVQSISD
INTLVATASQEQFSVTEDIAKNTTRTFDLVTQNVSAINQTQQAADELSKLAVAQKTELDFFKMN

Sequences:

>Translated_624_residues
MLLKNKILLFIFVLLVSIASALTWNGFNEFSQINKDLITKSTEDRSKLISVSLGEKLDGYFSSLRTFSISYHPDGRLDEV
TTTKDLRKLAENNDTNSAFIAFESGLTFENGQFIPNFNAKEVKREWFVRGFAGEKEIITDVYQNTDGVNVFAFAVPILSD
GKVVAVVAIGIEQNVLNAFIGTLTERGQIFTYNNLGYIIAAKNPDDVSKNIKNVEPELVDFDSGNTRFYDIDHDDYVLAS
ADNLSRYDWTVVMYEYEDDVYAPSMVMLKNSIIIFFSLLIISLAIVYYGVIYLIYKPIGGEPENISEILSNISEGDLSQQ
LVASDNDTGIYRSVVTLSSKLSEIVTSSHSISNSVSAASEELAVVMSDTAKNSQHELAQVEEISTAISELSSTSKEVTTN
AAQAEEEAQKAITNVSNGHNTLDNSIALTVDINESVQQTAEMISVLRDDAINIGEVTDVISSISEQTNLLALNAAIEAAR
AGEAGRGFAVVADEVRNLAAKTKESTSNIQEIISKLQAQSENANKNMMENVTSIQESVHLIESVKTSFNDIVSSVQSISD
INTLVATASQEQFSVTEDIAKNTTRTFDLVTQNVSAINQTQQAADELSKLAVAQKTELDFFKMN
>Mature_624_residues
MLLKNKILLFIFVLLVSIASALTWNGFNEFSQINKDLITKSTEDRSKLISVSLGEKLDGYFSSLRTFSISYHPDGRLDEV
TTTKDLRKLAENNDTNSAFIAFESGLTFENGQFIPNFNAKEVKREWFVRGFAGEKEIITDVYQNTDGVNVFAFAVPILSD
GKVVAVVAIGIEQNVLNAFIGTLTERGQIFTYNNLGYIIAAKNPDDVSKNIKNVEPELVDFDSGNTRFYDIDHDDYVLAS
ADNLSRYDWTVVMYEYEDDVYAPSMVMLKNSIIIFFSLLIISLAIVYYGVIYLIYKPIGGEPENISEILSNISEGDLSQQ
LVASDNDTGIYRSVVTLSSKLSEIVTSSHSISNSVSAASEELAVVMSDTAKNSQHELAQVEEISTAISELSSTSKEVTTN
AAQAEEEAQKAITNVSNGHNTLDNSIALTVDINESVQQTAEMISVLRDDAINIGEVTDVISSISEQTNLLALNAAIEAAR
AGEAGRGFAVVADEVRNLAAKTKESTSNIQEIISKLQAQSENANKNMMENVTSIQESVHLIESVKTSFNDIVSSVQSISD
INTLVATASQEQFSVTEDIAKNTTRTFDLVTQNVSAINQTQQAADELSKLAVAQKTELDFFKMN

Specific function: May function as an environmental regulator of TCP biogenesis. Negatively regulates the synthesis of the major pilin subunit of TCP (tcpA) [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=313, Percent_Identity=29.7124600638978, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI2367378, Length=307, Percent_Identity=30.2931596091205, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788194, Length=343, Percent_Identity=29.1545189504373, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1787690, Length=360, Percent_Identity=26.9444444444444, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1789453, Length=326, Percent_Identity=26.0736196319018, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 68421; Mature: 68421

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLKNKILLFIFVLLVSIASALTWNGFNEFSQINKDLITKSTEDRSKLISVSLGEKLDGY
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHEEEEECCHHHHHH
FSSLRTFSISYHPDGRLDEVTTTKDLRKLAENNDTNSAFIAFESGLTFENGQFIPNFNAK
HHHHHEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCEECCCCCCCCCCHH
EVKREWFVRGFAGEKEIITDVYQNTDGVNVFAFAVPILSDGKVVAVVAIGIEQNVLNAFI
HHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEEEEEECCCCEEEEEEECCHHHHHHHHH
GTLTERGQIFTYNNLGYIIAAKNPDDVSKNIKNVEPELVDFDSGNTRFYDIDHDDYVLAS
HHHHCCCEEEEECCCEEEEEECCHHHHHHHHHCCCCCEEECCCCCEEEEECCCCCEEEEE
ADNLSRYDWTVVMYEYEDDVYAPSMVMLKNSIIIFFSLLIISLAIVYYGVIYLIYKPIGG
CCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EPENISEILSNISEGDLSQQLVASDNDTGIYRSVVTLSSKLSEIVTSSHSISNSVSAASE
CCCHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ELAVVMSDTAKNSQHELAQVEEISTAISELSSTSKEVTTNAAQAEEEAQKAITNVSNGHN
HHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TLDNSIALTVDINESVQQTAEMISVLRDDAINIGEVTDVISSISEQTNLLALNAAIEAAR
CCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCEEEEHHHHHHHH
AGEAGRGFAVVADEVRNLAAKTKESTSNIQEIISKLQAQSENANKNMMENVTSIQESVHL
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
IESVKTSFNDIVSSVQSISDINTLVATASQEQFSVTEDIAKNTTRTFDLVTQNVSAINQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QQAADELSKLAVAQKTELDFFKMN
HHHHHHHHHHHHHHHCCCCEEECC
>Mature Secondary Structure
MLLKNKILLFIFVLLVSIASALTWNGFNEFSQINKDLITKSTEDRSKLISVSLGEKLDGY
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHEEEEECCHHHHHH
FSSLRTFSISYHPDGRLDEVTTTKDLRKLAENNDTNSAFIAFESGLTFENGQFIPNFNAK
HHHHHEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCEECCCCCCCCCCHH
EVKREWFVRGFAGEKEIITDVYQNTDGVNVFAFAVPILSDGKVVAVVAIGIEQNVLNAFI
HHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEEEEEECCCCEEEEEEECCHHHHHHHHH
GTLTERGQIFTYNNLGYIIAAKNPDDVSKNIKNVEPELVDFDSGNTRFYDIDHDDYVLAS
HHHHCCCEEEEECCCEEEEEECCHHHHHHHHHCCCCCEEECCCCCEEEEECCCCCEEEEE
ADNLSRYDWTVVMYEYEDDVYAPSMVMLKNSIIIFFSLLIISLAIVYYGVIYLIYKPIGG
CCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EPENISEILSNISEGDLSQQLVASDNDTGIYRSVVTLSSKLSEIVTSSHSISNSVSAASE
CCCHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ELAVVMSDTAKNSQHELAQVEEISTAISELSSTSKEVTTNAAQAEEEAQKAITNVSNGHN
HHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TLDNSIALTVDINESVQQTAEMISVLRDDAINIGEVTDVISSISEQTNLLALNAAIEAAR
CCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCEEEEHHHHHHHH
AGEAGRGFAVVADEVRNLAAKTKESTSNIQEIISKLQAQSENANKNMMENVTSIQESVHL
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
IESVKTSFNDIVSSVQSISDINTLVATASQEQFSVTEDIAKNTTRTFDLVTQNVSAINQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QQAADELSKLAVAQKTELDFFKMN
HHHHHHHHHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8005659 [H]