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The map label for this gene is tetD [H]

Identifier: 59714034

GI number: 59714034

Start: 960418

End: 961287

Strand: Reverse

Name: tetD [H]

Synonym: VF_A0851

Alternate gene names: 59714034

Gene position: 961287-960418 (Counterclockwise)

Preceding gene: 59714037

Following gene: 59714032

Centisome position: 72.26

GC content: 38.62

Gene sequence:

>870_bases
ATGAGCCGACAACATCTATCAAGAATTAATGATGTCTTATTTTATATTCACAAAGACATTAGCAAAGAGCTTGCAGTGAA
AGAGCTAGCAGATGTTGCTGCTTATTCTGAACAACATTTTCATCGAATCTTTAAACAAGTGGTGGGGGAATCCATTCATC
AATATATTCGTCGTACAAGAATGGAGTATGCCGCAAACCAATTGATGTTTGATACAAAATCATCTGTACTAGATATTGCA
AATACGTGTGGATTTAGTTCACTTTCTTCTTTTAGTCGTGCGTTTAAATCTACGTTTGGTATGGCACCAGGGGAGTGGAG
AAAACACGATTTACAAGTTTCGGATAAACCGTATTTAAAAGACGATGAAATTGCTGCAGGTTATGTCAGTGTCGCAGATA
AACCGTTGCCGCAGCCAAAGATTATTGAGGTGGAAGATAGACTTGCCGCTTATGTGAGGCATGAGGGTTACAATCGTTCT
ATTCGAAATGCATGGTTAATATTAAAAGCGTGGGCAAATTCAGAAGAGCGTGACTTTTCAACTCAATTTGGTTTGCATCA
TTCTAACCCTGCATGGGTTGAATTAGCTAAATGCCGATATGTCGCGTGTATAGCGATAGATAAACCACTTAAATATCGTG
GTGTCGTGAATCAAATGGTGATCCCTGGTGGTTTACACGGCGTATTTAAGTTAAGTGGTGTATATGGGCAACTTCTTCCA
CAGATTAGTCACGTATTGGAGCGATGGTTGCCGGCGTCGGGATTTAAATTGAGATCAACACCGGCTTACGTTCGTTACCA
CAAAAACCATTTTTTAAATGAAAACGAAGAGTTTGAGTTAGATTTTTATTTACCAATTAGCTTTTATTAA

Upstream 100 bases:

>100_bases
AAAATAATATTTTTTAACTGATCCGATAGTACAAGGCGTTGTATAACTTTGTTTGTCCGTTTATGCTTATAAATATGTCC
ATTTATGCTATTTTTCAATC

Downstream 100 bases:

>100_bases
TGCTCTCAATGCTTATCTTTTTTCTTGTTTTTAGAGAGGCGATCATAATGGAGATAATCACAATAATCAGTGCTGATTTT
TGACCTAAAGAAATAGGCTC

Product: transcriptional regulatory protein

Products: NA

Alternate protein names: ORFR [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MSRQHLSRINDVLFYIHKDISKELAVKELADVAAYSEQHFHRIFKQVVGESIHQYIRRTRMEYAANQLMFDTKSSVLDIA
NTCGFSSLSSFSRAFKSTFGMAPGEWRKHDLQVSDKPYLKDDEIAAGYVSVADKPLPQPKIIEVEDRLAAYVRHEGYNRS
IRNAWLILKAWANSEERDFSTQFGLHHSNPAWVELAKCRYVACIAIDKPLKYRGVVNQMVIPGGLHGVFKLSGVYGQLLP
QISHVLERWLPASGFKLRSTPAYVRYHKNHFLNENEEFELDFYLPISFY

Sequences:

>Translated_289_residues
MSRQHLSRINDVLFYIHKDISKELAVKELADVAAYSEQHFHRIFKQVVGESIHQYIRRTRMEYAANQLMFDTKSSVLDIA
NTCGFSSLSSFSRAFKSTFGMAPGEWRKHDLQVSDKPYLKDDEIAAGYVSVADKPLPQPKIIEVEDRLAAYVRHEGYNRS
IRNAWLILKAWANSEERDFSTQFGLHHSNPAWVELAKCRYVACIAIDKPLKYRGVVNQMVIPGGLHGVFKLSGVYGQLLP
QISHVLERWLPASGFKLRSTPAYVRYHKNHFLNENEEFELDFYLPISFY
>Mature_288_residues
SRQHLSRINDVLFYIHKDISKELAVKELADVAAYSEQHFHRIFKQVVGESIHQYIRRTRMEYAANQLMFDTKSSVLDIAN
TCGFSSLSSFSRAFKSTFGMAPGEWRKHDLQVSDKPYLKDDEIAAGYVSVADKPLPQPKIIEVEDRLAAYVRHEGYNRSI
RNAWLILKAWANSEERDFSTQFGLHHSNPAWVELAKCRYVACIAIDKPLKYRGVVNQMVIPGGLHGVFKLSGVYGQLLPQ
ISHVLERWLPASGFKLRSTPAYVRYHKNHFLNENEEFELDFYLPISFY

Specific function: Binds To The Right Arm Of The Replication Origin Oric Of The E.Coli Chromosome. Rob Binding May Influence The Formation Of The Nucleoprotein Structure, Required For Oric Function In The Initiation Of Replication. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790857, Length=287, Percent_Identity=24.7386759581882, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87081928, Length=114, Percent_Identity=29.8245614035088, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 33362; Mature: 33231

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRQHLSRINDVLFYIHKDISKELAVKELADVAAYSEQHFHRIFKQVVGESIHQYIRRTR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MEYAANQLMFDTKSSVLDIANTCGFSSLSSFSRAFKSTFGMAPGEWRKHDLQVSDKPYLK
HHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
DDEIAAGYVSVADKPLPQPKIIEVEDRLAAYVRHEGYNRSIRNAWLILKAWANSEERDFS
CCCCCHHHHHHCCCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHEEEEEECCCCCCCCCH
TQFGLHHSNPAWVELAKCRYVACIAIDKPLKYRGVVNQMVIPGGLHGVFKLSGVYGQLLP
HHCCCCCCCCHHEEHHHHEEEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
QISHVLERWLPASGFKLRSTPAYVRYHKNHFLNENEEFELDFYLPISFY
HHHHHHHHHCCCCCCEECCCCHHEEEHHHHCCCCCCCEEEEEEEEEECC
>Mature Secondary Structure 
SRQHLSRINDVLFYIHKDISKELAVKELADVAAYSEQHFHRIFKQVVGESIHQYIRRTR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MEYAANQLMFDTKSSVLDIANTCGFSSLSSFSRAFKSTFGMAPGEWRKHDLQVSDKPYLK
HHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
DDEIAAGYVSVADKPLPQPKIIEVEDRLAAYVRHEGYNRSIRNAWLILKAWANSEERDFS
CCCCCHHHHHHCCCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHEEEEEECCCCCCCCCH
TQFGLHHSNPAWVELAKCRYVACIAIDKPLKYRGVVNQMVIPGGLHGVFKLSGVYGQLLP
HHCCCCCCCCHHEEHHHHEEEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
QISHVLERWLPASGFKLRSTPAYVRYHKNHFLNENEEFELDFYLPISFY
HHHHHHHHHCCCCCCEECCCCHHEEEHHHHCCCCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6094471; 6094472 [H]