Click here to switch to the map view.

The map label for this gene is manP [H]

Identifier: 59713895

GI number: 59713895

Start: 798632

End: 798931

Strand: Reverse

Name: manP [H]

Synonym: VF_A0712

Alternate gene names: 59713895

Gene position: 798931-798632 (Counterclockwise)

Preceding gene: 59713897

Following gene: 59713894

Centisome position: 60.05

GC content: 36.33

Gene sequence:

>300_bases
ATGAAAATTGTAGCAGTTACCGCTTGTCCTACAGGAATCGCACATACTTATATGGCTGCGGATGTATTGAAAAAAGCGGC
AGCAAAGTTAGGTGTCTCAATTAAAGTGGAAACACAAGGTGCAATGGGGGTAGAAAATGTACTGACACCCGTTGATATCG
TCAGTGCTGATTTAGTTATTATTGCATCGGATATCGAGATTGAAGATAAAAATCGTTTTTTAGGAATTAATTCAAAACAA
TTCCCAATTGAAACCATATTAACGGATGTTGAAGGTATACTGAAAAAACACCTTTTCTAA

Upstream 100 bases:

>100_bases
TAAAGTGTGAGTTTCATCCTTATTCATTTATATAAAGCAATTTATCATAAATAACAGATATATATCGAACATTTAAATTG
TAATAAGAAAAGAGTTAATA

Downstream 100 bases:

>100_bases
TGGAGCTTAATACTATCGATTACCGAATTACTTTTTTTGTAAAAGATCAGGGCTTGCCACCTCAAGTTGCAAGTCAATTA
ACCCGTCTTGCTAAAAAGTT

Product: hypothetical protein

Products: NA

Alternate protein names: EIIBCA-Man; EII-Man; Mannose-specific phosphotransferase enzyme IIB component; PTS system mannose-specific EIIB component; Mannose permease IIC component; PTS system mannose-specific EIIC component; Mannose-specific phosphotransferase enzyme IIA component; PTS system mannose-specific EIIA component [H]

Number of amino acids: Translated: 99; Mature: 99

Protein sequence:

>99_residues
MKIVAVTACPTGIAHTYMAADVLKKAAAKLGVSIKVETQGAMGVENVLTPVDIVSADLVIIASDIEIEDKNRFLGINSKQ
FPIETILTDVEGILKKHLF

Sequences:

>Translated_99_residues
MKIVAVTACPTGIAHTYMAADVLKKAAAKLGVSIKVETQGAMGVENVLTPVDIVSADLVIIASDIEIEDKNRFLGINSKQ
FPIETILTDVEGILKKHLF
>Mature_99_residues
MKIVAVTACPTGIAHTYMAADVLKKAAAKLGVSIKVETQGAMGVENVLTPVDIVSADLVIIASDIEIEDKNRFLGINSKQ
FPIETILTDVEGILKKHLF

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1445

COG function: function code G; Phosphotransferase system fructose-specific component IIB

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790387, Length=74, Percent_Identity=58.1081081081081, Blast_Score=93, Evalue=4e-21,
Organism=Escherichia coli, GI1786951, Length=96, Percent_Identity=45.8333333333333, Blast_Score=86, Evalue=7e-19,
Organism=Escherichia coli, GI1788492, Length=74, Percent_Identity=52.7027027027027, Blast_Score=85, Evalue=1e-18,
Organism=Escherichia coli, GI87082348, Length=98, Percent_Identity=43.8775510204082, Blast_Score=83, Evalue=3e-18,
Organism=Escherichia coli, GI1788730, Length=95, Percent_Identity=38.9473684210526, Blast_Score=79, Evalue=5e-17,
Organism=Escherichia coli, GI1790390, Length=94, Percent_Identity=44.6808510638298, Blast_Score=74, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 10593; Mature: 10593

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVAVTACPTGIAHTYMAADVLKKAAAKLGVSIKVETQGAMGVENVLTPVDIVSADLVI
CEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHCCCHHHCCCCEEE
IASDIEIEDKNRFLGINSKQFPIETILTDVEGILKKHLF
EEECCEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIVAVTACPTGIAHTYMAADVLKKAAAKLGVSIKVETQGAMGVENVLTPVDIVSADLVI
CEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHCCCHHHCCCCEEE
IASDIEIEDKNRFLGINSKQFPIETILTDVEGILKKHLF
EEECCEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]