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The map label for this gene is ppiC [H]

Identifier: 59713880

GI number: 59713880

Start: 773927

End: 774205

Strand: Reverse

Name: ppiC [H]

Synonym: VF_A0697

Alternate gene names: 59713880

Gene position: 774205-773927 (Counterclockwise)

Preceding gene: 59713882

Following gene: 59713878

Centisome position: 58.2

GC content: 38.35

Gene sequence:

>279_bases
ATGGCGAATACTGCAGCGGCTCTACATATTCTTGTTAAGCATAAAGAACAAGCAGAAGATATTATCCAACAGCTTAAAAA
AGGCGCTAAGTTTCACGTACTAGCAAAGAAATATTCAAGCTGTCCTTCTGGTAAAAGAGGCGGTGACTTAGGTGAATTCA
AGAAAGGTCAAATGGTACCTCAGTTTGATAAAGTGTGTTTTAGCGGCGAAACTTTAGTTCCACATTTAGTAAAAACAAAG
TTCGGTTGGCATGTTGTTAAGGTTCTATACCGCACTTAA

Upstream 100 bases:

>100_bases
GTAGTTTTTTTGAGACGGTTTTTAAAGGTGAGACTATCAATTATGGTGACATAAACGATATAATTACGCTAAATCGTTAT
TTAAATAAATTGAGGCATTC

Downstream 100 bases:

>100_bases
TTAAAACTGAATTATAAATACAAAAAATCCGACGTTTAACCGTCGGATTTTTTTATGAACCAGATGCTAATAGGATTTAA
CGCTCCCAGTAAGCTTCTTC

Product: peptidyl-prolyl cis-trans isomerase C (rotamase C)

Products: NA

Alternate protein names: PPIase C; Parvulin; Rotamase C [H]

Number of amino acids: Translated: 92; Mature: 91

Protein sequence:

>92_residues
MANTAAALHILVKHKEQAEDIIQQLKKGAKFHVLAKKYSSCPSGKRGGDLGEFKKGQMVPQFDKVCFSGETLVPHLVKTK
FGWHVVKVLYRT

Sequences:

>Translated_92_residues
MANTAAALHILVKHKEQAEDIIQQLKKGAKFHVLAKKYSSCPSGKRGGDLGEFKKGQMVPQFDKVCFSGETLVPHLVKTK
FGWHVVKVLYRT
>Mature_91_residues
ANTAAALHILVKHKEQAEDIIQQLKKGAKFHVLAKKYSSCPSGKRGGDLGEFKKGQMVPQFDKVCFSGETLVPHLVKTKF
GWHVVKVLYRT

Specific function: PPIases accelerate the folding of proteins. It prefers amino acid residues with hydrophobic side chains like leucine and phenylalanine in the P1 position of the peptides substrates [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1790211, Length=93, Percent_Identity=63.4408602150538, Blast_Score=119, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 10279; Mature: 10148

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTAAALHILVKHKEQAEDIIQQLKKGAKFHVLAKKYSSCPSGKRGGDLGEFKKGQMVP
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHCCCCCCCCCCCCCCCCCCCCC
QFDKVCFSGETLVPHLVKTKFGWHVVKVLYRT
HHHHHHHCCCCHHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure 
ANTAAALHILVKHKEQAEDIIQQLKKGAKFHVLAKKYSSCPSGKRGGDLGEFKKGQMVP
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHCCCCCCCCCCCCCCCCCCCCC
QFDKVCFSGETLVPHLVKTKFGWHVVKVLYRT
HHHHHHHCCCCHHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]