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The map label for this gene is intA [H]

Identifier: 59713731

GI number: 59713731

Start: 630681

End: 631880

Strand: Reverse

Name: intA [H]

Synonym: VF_A0548

Alternate gene names: 59713731

Gene position: 631880-630681 (Counterclockwise)

Preceding gene: 59713732

Following gene: 59713705

Centisome position: 47.5

GC content: 38.5

Gene sequence:

>1200_bases
ATGGCTCGTCAAGTAATTCGTCTTACTGATAGAAAGATAAAATCAGCAGCACCAACAGGGAAAGAATTTACATTATCTGA
TGGTGAAGGATTACAATTGCGTGTACGTCCAACTGGGGCTAAATCATGGCAATTTAAATTCAGTGACCCTGTAACAAGAA
AGATTCAGAAAATAGCACTTGGCCCTTATCCTGAATTATCTCTTGCTAATGCTCGATCCAAAACAACTGAGTACCGAACA
CTCTTAGCTCAAAAAATCAACCCTAAGTCATTTGAACAAAGTAAAGAGCTTGAGGCGAAAAGAGTACAGACGTCGACTTT
TATCGTAGTTGCAGAACAATGGTTTGAACGAAAAAAAGAAACGGTTTCTCCTGCGCATTCATACCGGGAATGGCGGACAT
TAGAAAAATATATTTTCCCTCATATGAGCAAAATTCCTGTTGCTACGATCACTGCTGTAGAAACAATAGATGTATTACGA
CCTCTAGAAAAAGAAGGTAAATACTCGACGGTTAAACGAATTTGCCAAAGCCTTAACCAAATCATGGATTACTCAGTTAA
CCACGGTTTAATACACGCAAATCCATTAGCAAAAATAATTAAAGTTTTTCGTAAAAATACAGTTTTGCACATGCCTACTA
TTCGGCCAGAGCAATTACCTGATTTTTTAAAACGACTGCATTCATGTTCAACAATACAAACTAAAACTAAATTGCTCATT
TTATGGCAGCTACACACAATGACGCGCCCAAAGGAAGCGGCAACAACTCGCTGGATAGATATTGATTTAGAAAAAGGCGT
ATGGACTATCCCTGCTGAGAATATGAAACGCAGAAAAGAACACCGTATACCGCTGACATCACAAGCAATCAACATTCTGA
ATCAGATTCGATTACAAAGCAAACGATGTGATTATGTCTTTCCTGGTGAGCGAGATATAAATAGCCATGTAAGCTTGTTT
ACAGCAAATGCAGCCATAAAGCGTAGTCTTGGGCTAAAAGATGAGTTAGTTGCTCATGGATTGCGTGCTATAGCTTCTAC
TGCCCTTCACGAGTACGGTTTTGATAGTTTATTGATTGAAGCTTGTTTATCACATGCCGACCAAAATGAAGTGAGAGCCA
GTTACAACCGTTCTGATTATTTAGAACAAAGAAAAGAGATTATGTGCTGGTGGAGTAATTATATAGATGAGGCAGCGTAA

Upstream 100 bases:

>100_bases
ACTAAATAGTACCCCAAGCCAGCATTTTTAGTACCCCAGGATGTACCCCATGATCCAAAACTAATATATACTGTTTCTAT
CTAGTTTTGAGGTAATCATC

Downstream 100 bases:

>100_bases
AGCTGCCTCTTCATTAAATAAATTAAAGCCGCTACTGGACTCGATTATACAATCCATATTTTTGATTAATAATCATAGTA
TTTAAAATATTACTCTAACT

Product: phage family integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MARQVIRLTDRKIKSAAPTGKEFTLSDGEGLQLRVRPTGAKSWQFKFSDPVTRKIQKIALGPYPELSLANARSKTTEYRT
LLAQKINPKSFEQSKELEAKRVQTSTFIVVAEQWFERKKETVSPAHSYREWRTLEKYIFPHMSKIPVATITAVETIDVLR
PLEKEGKYSTVKRICQSLNQIMDYSVNHGLIHANPLAKIIKVFRKNTVLHMPTIRPEQLPDFLKRLHSCSTIQTKTKLLI
LWQLHTMTRPKEAATTRWIDIDLEKGVWTIPAENMKRRKEHRIPLTSQAINILNQIRLQSKRCDYVFPGERDINSHVSLF
TANAAIKRSLGLKDELVAHGLRAIASTALHEYGFDSLLIEACLSHADQNEVRASYNRSDYLEQRKEIMCWWSNYIDEAA

Sequences:

>Translated_399_residues
MARQVIRLTDRKIKSAAPTGKEFTLSDGEGLQLRVRPTGAKSWQFKFSDPVTRKIQKIALGPYPELSLANARSKTTEYRT
LLAQKINPKSFEQSKELEAKRVQTSTFIVVAEQWFERKKETVSPAHSYREWRTLEKYIFPHMSKIPVATITAVETIDVLR
PLEKEGKYSTVKRICQSLNQIMDYSVNHGLIHANPLAKIIKVFRKNTVLHMPTIRPEQLPDFLKRLHSCSTIQTKTKLLI
LWQLHTMTRPKEAATTRWIDIDLEKGVWTIPAENMKRRKEHRIPLTSQAINILNQIRLQSKRCDYVFPGERDINSHVSLF
TANAAIKRSLGLKDELVAHGLRAIASTALHEYGFDSLLIEACLSHADQNEVRASYNRSDYLEQRKEIMCWWSNYIDEAA
>Mature_398_residues
ARQVIRLTDRKIKSAAPTGKEFTLSDGEGLQLRVRPTGAKSWQFKFSDPVTRKIQKIALGPYPELSLANARSKTTEYRTL
LAQKINPKSFEQSKELEAKRVQTSTFIVVAEQWFERKKETVSPAHSYREWRTLEKYIFPHMSKIPVATITAVETIDVLRP
LEKEGKYSTVKRICQSLNQIMDYSVNHGLIHANPLAKIIKVFRKNTVLHMPTIRPEQLPDFLKRLHSCSTIQTKTKLLIL
WQLHTMTRPKEAATTRWIDIDLEKGVWTIPAENMKRRKEHRIPLTSQAINILNQIRLQSKRCDYVFPGERDINSHVSLFT
ANAAIKRSLGLKDELVAHGLRAIASTALHEYGFDSLLIEACLSHADQNEVRASYNRSDYLEQRKEIMCWWSNYIDEAA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=398, Percent_Identity=41.7085427135678, Blast_Score=336, Evalue=2e-93,
Organism=Escherichia coli, GI145693166, Length=396, Percent_Identity=31.8181818181818, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1788690, Length=399, Percent_Identity=28.3208020050125, Blast_Score=164, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 46008; Mature: 45876

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARQVIRLTDRKIKSAAPTGKEFTLSDGEGLQLRVRPTGAKSWQFKFSDPVTRKIQKIAL
CCCHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEECCCCCCEEEECCCHHHHHHHHHHC
GPYPELSLANARSKTTEYRTLLAQKINPKSFEQSKELEAKRVQTSTFIVVAEQWFERKKE
CCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHH
TVSPAHSYREWRTLEKYIFPHMSKIPVATITAVETIDVLRPLEKEGKYSTVKRICQSLNQ
HCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IMDYSVNHGLIHANPLAKIIKVFRKNTVLHMPTIRPEQLPDFLKRLHSCSTIQTKTKLLI
HHCCCCCCCEEECCHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHCCCHHHHCCEEEE
LWQLHTMTRPKEAATTRWIDIDLEKGVWTIPAENMKRRKEHRIPLTSQAINILNQIRLQS
EEEEHHCCCCCHHHCEEEEEEEECCCEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
KRCDYVFPGERDINSHVSLFTANAAIKRSLGLKDELVAHGLRAIASTALHEYGFDSLLIE
CCCCEECCCCCCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHH
ACLSHADQNEVRASYNRSDYLEQRKEIMCWWSNYIDEAA
HHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ARQVIRLTDRKIKSAAPTGKEFTLSDGEGLQLRVRPTGAKSWQFKFSDPVTRKIQKIAL
CCHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEECCCCCCEEEECCCHHHHHHHHHHC
GPYPELSLANARSKTTEYRTLLAQKINPKSFEQSKELEAKRVQTSTFIVVAEQWFERKKE
CCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHH
TVSPAHSYREWRTLEKYIFPHMSKIPVATITAVETIDVLRPLEKEGKYSTVKRICQSLNQ
HCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IMDYSVNHGLIHANPLAKIIKVFRKNTVLHMPTIRPEQLPDFLKRLHSCSTIQTKTKLLI
HHCCCCCCCEEECCHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHCCCHHHHCCEEEE
LWQLHTMTRPKEAATTRWIDIDLEKGVWTIPAENMKRRKEHRIPLTSQAINILNQIRLQS
EEEEHHCCCCCHHHCEEEEEEEECCCEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
KRCDYVFPGERDINSHVSLFTANAAIKRSLGLKDELVAHGLRAIASTALHEYGFDSLLIE
CCCCEECCCCCCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHH
ACLSHADQNEVRASYNRSDYLEQRKEIMCWWSNYIDEAA
HHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]