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The map label for this gene is 59713532

Identifier: 59713532

GI number: 59713532

Start: 389729

End: 390508

Strand: Reverse

Name: 59713532

Synonym: VF_A0349

Alternate gene names: NA

Gene position: 390508-389729 (Counterclockwise)

Preceding gene: 59713533

Following gene: 59713531

Centisome position: 29.35

GC content: 37.31

Gene sequence:

>780_bases
ATGCCTGATAAATCATTAAAGAACAAAAATATCATCACTCATATGATGGATCTATTCTCTAATCGCCATCCATTGCACCG
TTTAGAAGAGCAGAGACAAGCATTAATTGAACAAAATTTAACGCTACCTGATTATTTAGTCTGTTTTCTTAAATCATCTT
ATCCAAGCCCGAAAGAAAACAGTAATGATATGGCGTTCACCGTTGTGGATTTTGAAACCTCAGGGTTAAATCCGAAAACC
GATCATATCGTGAGCGTTGGTTGGGTTCACATTATTGATGGCGTAATCAAACTCAGCAGTGCCCAGCACCATATCATCAA
TGAACCAACCTCAATAAGTGCAGAGGATGGACATGAAGAAAGAGAGCATATCGCACGCTCATTGCATCACATTTTACCTG
AGCAACAAAAAATGGGGATTTCACTCGAAGAGGCAATGGAATGTTTCTTTTCAAATTTACCTAGCAATATTCTTGTTGTT
CATGGAGCAACTATTGAGCAGCGGTTTTTAGAGCAATTTATCCTTTCTCTACAATTGCCAAATTTACCTATAATTTGGCT
AGATACGCTTAGAATTGAACAAAATACAATTCAACAAAACCGTTATCAAAGAGATTTCCGTTTATTCTCCCTTAGACGTC
AATATAAGCTACCTGACTACCCCGCTCATCACGCTTTAGTCGATGCTATTTCAACTGCTGAGCTTTTTTTAGCTCAAAAA
AAACGTCTATTTAATCAAGCTATTGCCCCTATTGGCTTCCTATATCAAAAATCTCAATAG

Upstream 100 bases:

>100_bases
TGATTTATTTGGTAGTTTTGAACGTCAGCATTTAAAAGATGCATTTCGTATCGTTTCAAACTTTCAAGAATTAATGAAAA
TGAAATTTGGTGTCTAGTAC

Downstream 100 bases:

>100_bases
CAACCACAGTAAAACTTTAGTAAAAGCCATTTTTAAGTATCAAAATCATCATTTATTAAGTAACATGGAGCAATATTATA
AAATTAAAGGCTGGAGGATG

Product: DNA polymerase III, epsilon-subunit paralog (3' to 5' exonuclease)

Products: diphosphate; DNAn+1

Alternate protein names: Exonuclease RNAse T And DNA Polymerase III; DNA Polymerase III Epsilon Subunit; Exonuclease; DNA Polymerase Exonuclease Activity; Exonuclease Superfamily; DNA Polymerase; DNA Polymerase III PolC-Type; 3-5' Exonuclease; DNA Polymerase III; Exonuclase; DNA Polymerase III Epsilon-Subunit Paralog

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MPDKSLKNKNIITHMMDLFSNRHPLHRLEEQRQALIEQNLTLPDYLVCFLKSSYPSPKENSNDMAFTVVDFETSGLNPKT
DHIVSVGWVHIIDGVIKLSSAQHHIINEPTSISAEDGHEEREHIARSLHHILPEQQKMGISLEEAMECFFSNLPSNILVV
HGATIEQRFLEQFILSLQLPNLPIIWLDTLRIEQNTIQQNRYQRDFRLFSLRRQYKLPDYPAHHALVDAISTAELFLAQK
KRLFNQAIAPIGFLYQKSQ

Sequences:

>Translated_259_residues
MPDKSLKNKNIITHMMDLFSNRHPLHRLEEQRQALIEQNLTLPDYLVCFLKSSYPSPKENSNDMAFTVVDFETSGLNPKT
DHIVSVGWVHIIDGVIKLSSAQHHIINEPTSISAEDGHEEREHIARSLHHILPEQQKMGISLEEAMECFFSNLPSNILVV
HGATIEQRFLEQFILSLQLPNLPIIWLDTLRIEQNTIQQNRYQRDFRLFSLRRQYKLPDYPAHHALVDAISTAELFLAQK
KRLFNQAIAPIGFLYQKSQ
>Mature_258_residues
PDKSLKNKNIITHMMDLFSNRHPLHRLEEQRQALIEQNLTLPDYLVCFLKSSYPSPKENSNDMAFTVVDFETSGLNPKTD
HIVSVGWVHIIDGVIKLSSAQHHIINEPTSISAEDGHEEREHIARSLHHILPEQQKMGISLEEAMECFFSNLPSNILVVH
GATIEQRFLEQFILSLQLPNLPIIWLDTLRIEQNTIQQNRYQRDFRLFSLRRQYKLPDYPAHHALVDAISTAELFLAQKK
RLFNQAIAPIGFLYQKSQ

Specific function: Unknown

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.7

Molecular weight: Translated: 29983; Mature: 29852

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDKSLKNKNIITHMMDLFSNRHPLHRLEEQRQALIEQNLTLPDYLVCFLKSSYPSPKEN
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCC
SNDMAFTVVDFETSGLNPKTDHIVSVGWVHIIDGVIKLSSAQHHIINEPTSISAEDGHEE
CCCEEEEEEEEECCCCCCCCCCEEHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCHHH
REHIARSLHHILPEQQKMGISLEEAMECFFSNLPSNILVVHGATIEQRFLEQFILSLQLP
HHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCC
NLPIIWLDTLRIEQNTIQQNRYQRDFRLFSLRRQYKLPDYPAHHALVDAISTAELFLAQK
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
KRLFNQAIAPIGFLYQKSQ
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PDKSLKNKNIITHMMDLFSNRHPLHRLEEQRQALIEQNLTLPDYLVCFLKSSYPSPKEN
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCC
SNDMAFTVVDFETSGLNPKTDHIVSVGWVHIIDGVIKLSSAQHHIINEPTSISAEDGHEE
CCCEEEEEEEEECCCCCCCCCCEEHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCHHH
REHIARSLHHILPEQQKMGISLEEAMECFFSNLPSNILVVHGATIEQRFLEQFILSLQLP
HHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCC
NLPIIWLDTLRIEQNTIQQNRYQRDFRLFSLRRQYKLPDYPAHHALVDAISTAELFLAQK
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
KRLFNQAIAPIGFLYQKSQ
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA