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The map label for this gene is sapC [H]

Identifier: 59713490

GI number: 59713490

Start: 341413

End: 342300

Strand: Reverse

Name: sapC [H]

Synonym: VF_A0307

Alternate gene names: 59713490

Gene position: 342300-341413 (Counterclockwise)

Preceding gene: 59713491

Following gene: 59713489

Centisome position: 25.73

GC content: 40.2

Gene sequence:

>888_bases
ATGCTCTCAAATAATGTTTATCAAGAAGAACATATCCCTACTCAAATGGAACGTTTCTGGTTGAGTTATCGAGCGAATTC
ACTCGCGATGTTCGGTTTTTGGTGCTTATTACTGATTGTAATTATCACCGTCACCTCGCCATGGTTAAGTCCATATGATC
CACAATGGCAGTCAGATTATTTACTGATGCCTCCATCATGGAGCTCTGAGGGGGAGGTTATCTTTTTCTTAGGTACTGAC
GACCTAGGTAGAGATATCTTGTCACGATTACTTATGGGATCACAATTAACTTTTGGTTATGCGGTTATCGTTGCCCTGCT
ATCAGGGTTTGTTGGCTGCGTAATTGGTATTTTTGCAGGTATGACAAAGGGATTACTATCCAGTACGTTAAACCACCTAC
TCGATACCATTTTATCTATCCCATCTTTATTGCTTGCGATCATTTTCGTGGCATTTTTAGGATTTGGGGAATTTAATATT
TTATTAGCTATTTGGCTCGCGCTTATCCCACGCTTTGTTCGAGCTGTTTATACAGCGGTTCATAATGAGGTTGAAAAGGA
TTATATTCTTGCTGCACGATTAGATGGAGCAAACAACTTCTATCTCTTATGGAATTCCATATTACCTAATATTCTTGTCG
TTATGGTTGCAGAAATGACGCTTGCTATCTCTATTGCCATTTTAGATATCACTGCGTTAGGTTTTCTAGGTTTAGGAGCA
CAGGCTCCTAGTCCCGAGTGGGGAGCCATGTTAGGAGATTCTGTTGAGTTAATTTATACAGCACCATGGACAGTGACGTT
ACCTGGAATTGTAATTACCTTTACAGTCATCATCATCAACTTAGTTGGTGACGGTATTCAACGTGCGTTAAATGCGGGGA
CAGAATAA

Upstream 100 bases:

>100_bases
CAGGCTGGCGTTATAACTGTTGCGTCATTCATTTTATTAGCCAACATTTTATCTGATTTACTGGGTGCAGCAGTTAACCC
GTTAGTAAGGAAAGAGTTCT

Downstream 100 bases:

>100_bases
TGCCATTATTAGATATTCGCCATTTAACCATTGAGTTAGAAACGCCACAAGGCATGGTGAAAGCCGTTGACCGCATGAGC
TTAACCTTAAATGAAGGTGA

Product: peptide transport system permease protein SapC

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MLSNNVYQEEHIPTQMERFWLSYRANSLAMFGFWCLLLIVIITVTSPWLSPYDPQWQSDYLLMPPSWSSEGEVIFFLGTD
DLGRDILSRLLMGSQLTFGYAVIVALLSGFVGCVIGIFAGMTKGLLSSTLNHLLDTILSIPSLLLAIIFVAFLGFGEFNI
LLAIWLALIPRFVRAVYTAVHNEVEKDYILAARLDGANNFYLLWNSILPNILVVMVAEMTLAISIAILDITALGFLGLGA
QAPSPEWGAMLGDSVELIYTAPWTVTLPGIVITFTVIIINLVGDGIQRALNAGTE

Sequences:

>Translated_295_residues
MLSNNVYQEEHIPTQMERFWLSYRANSLAMFGFWCLLLIVIITVTSPWLSPYDPQWQSDYLLMPPSWSSEGEVIFFLGTD
DLGRDILSRLLMGSQLTFGYAVIVALLSGFVGCVIGIFAGMTKGLLSSTLNHLLDTILSIPSLLLAIIFVAFLGFGEFNI
LLAIWLALIPRFVRAVYTAVHNEVEKDYILAARLDGANNFYLLWNSILPNILVVMVAEMTLAISIAILDITALGFLGLGA
QAPSPEWGAMLGDSVELIYTAPWTVTLPGIVITFTVIIINLVGDGIQRALNAGTE
>Mature_295_residues
MLSNNVYQEEHIPTQMERFWLSYRANSLAMFGFWCLLLIVIITVTSPWLSPYDPQWQSDYLLMPPSWSSEGEVIFFLGTD
DLGRDILSRLLMGSQLTFGYAVIVALLSGFVGCVIGIFAGMTKGLLSSTLNHLLDTILSIPSLLLAIIFVAFLGFGEFNI
LLAIWLALIPRFVRAVYTAVHNEVEKDYILAARLDGANNFYLLWNSILPNILVVMVAEMTLAISIAILDITALGFLGLGA
QAPSPEWGAMLGDSVELIYTAPWTVTLPGIVITFTVIIINLVGDGIQRALNAGTE

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4171

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787549, Length=297, Percent_Identity=53.1986531986532, Blast_Score=315, Evalue=2e-87,
Organism=Escherichia coli, GI1789964, Length=279, Percent_Identity=40.1433691756272, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI1787054, Length=284, Percent_Identity=32.0422535211268, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI1787760, Length=286, Percent_Identity=33.5664335664336, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1789889, Length=251, Percent_Identity=33.4661354581673, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787498, Length=293, Percent_Identity=30.0341296928328, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788505, Length=221, Percent_Identity=25.7918552036199, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32440; Mature: 32440

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSNNVYQEEHIPTQMERFWLSYRANSLAMFGFWCLLLIVIITVTSPWLSPYDPQWQSDY
CCCCCCCCHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCE
LLMPPSWSSEGEVIFFLGTDDLGRDILSRLLMGSQLTFGYAVIVALLSGFVGCVIGIFAG
EEECCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MTKGLLSSTLNHLLDTILSIPSLLLAIIFVAFLGFGEFNILLAIWLALIPRFVRAVYTAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
HNEVEKDYILAARLDGANNFYLLWNSILPNILVVMVAEMTLAISIAILDITALGFLGLGA
HHHHHHHHEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QAPSPEWGAMLGDSVELIYTAPWTVTLPGIVITFTVIIINLVGDGIQRALNAGTE
CCCCCCHHHHCCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLSNNVYQEEHIPTQMERFWLSYRANSLAMFGFWCLLLIVIITVTSPWLSPYDPQWQSDY
CCCCCCCCHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCE
LLMPPSWSSEGEVIFFLGTDDLGRDILSRLLMGSQLTFGYAVIVALLSGFVGCVIGIFAG
EEECCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MTKGLLSSTLNHLLDTILSIPSLLLAIIFVAFLGFGEFNILLAIWLALIPRFVRAVYTAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
HNEVEKDYILAARLDGANNFYLLWNSILPNILVVMVAEMTLAISIAILDITALGFLGLGA
HHHHHHHHEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QAPSPEWGAMLGDSVELIYTAPWTVTLPGIVITFTVIIINLVGDGIQRALNAGTE
CCCCCCHHHHCCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]