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The map label for this gene is glpC [H]

Identifier: 59713431

GI number: 59713431

Start: 275235

End: 276506

Strand: Reverse

Name: glpC [H]

Synonym: VF_A0248

Alternate gene names: 59713431

Gene position: 276506-275235 (Counterclockwise)

Preceding gene: 59713432

Following gene: 59713430

Centisome position: 20.78

GC content: 37.34

Gene sequence:

>1272_bases
ATGAGCAGCCCATTATTTAAGTCGTCTTTTCTAAAAGACAGTGTATTAAAAGACAATCTTATTTTTAGAGCACCCGCGAA
TACCAGTTTTGATCAATGTTTAAAATGCACCGTTTGTACCGTCTATTGTCCAGTAGCAAAAGAAAACCCTGATTATCCAG
GGCCAAAACAATGCGGACCAGATGGCGAACGCCTACGCTTTAAAAGCCCAGAATACTATGATGAAACCCTTAAACTTTGC
ACAAATTGCAAACGTTGTGAAACCGCTTGTCCATCTGGGGTAAAAATTGGCGACATGATTGCAGTTGCTCGTGGAAAATA
TGGCAAGCCAGCATACAACATGAAAGGTCTTCGTGATTTTGTATTAAGTCATACGGATCTATTTGGTTCAATTGCCACTC
CTGTAGCACCTGTTGTAAACGCAGTTACCAGCGTTCCTTTAGTAAAAAAAGTAATGCATAAAACCATTGGTGTACATGAT
CATAAATCACTGCCTAAATACTCTCATGGTACTTTTAGAAAATGGTATAAAAAAGAAGTGAATGATCAGAGTGTATTTGA
GCGACAAGTGCATTATTTTCATGGCTGTTTTGTCAACTACAACCATCCACAACTAGGTAAAGACTTCATTAAAGTAATGA
ACAATATGAACATCGGGGTTCAATTGTTAGATAAAGAAAAATGTTGTGGTGTCCCTCTTATTGCTAATGGTTTTCATAAA
AAAGCACAGAAGAATGCAGAATTTAATGTGGCTAACTTAGAAGCTGCGATTGAACGTCAAGATGTTCCGATTCTATCCAC
CTCTTCAACCTGTTCATTTACTTTGCAACAAGAGTACCCTCATGTTCTAGATGTAGATAACACTAAAGTAGCCAAAAAGA
TTGAATACGTTACTCGTTTCTTATTAAAAGAAATCATGAATGGTCGAGGACCTAAAATGAAGCCTCTAAATAAGAAAATT
GTTTATCACACTCCTTGTCACTTAGAACGCAGTGGCGGCAATATTTATACTATTGAGTTACTCCGAGCAATTCCTGGCTT
AGAGGTGCAGGTATTAGATAGTGAATGCTGTGGTTTAGCGGGCACTTATGGATTTAAAACTGAAAACTACGAAACATCAG
TTGCGATAGGTAAGAATATATTCGACAAAATTAAAGCTGCCAAACCTGATTACGCAATTACTGATTGTGAAACTTGTAAA
TGGCAAATCGAAGAAAACACTAACACCACAACCATCCATCCTATTTCACTGCTTTGTGAAGCTCTAATCTAA

Upstream 100 bases:

>100_bases
TTGCAATTAGTTCAGGCTTTCACGCTGCAGAATCTATCATAGAGCAATTACAGTGCAGCGACTCTTTACAAAATAACAAT
ACGAAAGCAGAGGTCGCGTT

Downstream 100 bases:

>100_bases
CCTTTGTATATTTGTGGGTATAACACCCACAAATATCACCAAAACCAATTAAAATTAAATTATAAATTCACAAGAAAAAT
ACCAAAACATTACCAAACTC

Product: sn-glycerol-3-phosphate dehydrogenase subunit C

Products: FADH2; dihydroxy-acetone-phosphate [C]

Alternate protein names: G-3-P dehydrogenase [H]

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MSSPLFKSSFLKDSVLKDNLIFRAPANTSFDQCLKCTVCTVYCPVAKENPDYPGPKQCGPDGERLRFKSPEYYDETLKLC
TNCKRCETACPSGVKIGDMIAVARGKYGKPAYNMKGLRDFVLSHTDLFGSIATPVAPVVNAVTSVPLVKKVMHKTIGVHD
HKSLPKYSHGTFRKWYKKEVNDQSVFERQVHYFHGCFVNYNHPQLGKDFIKVMNNMNIGVQLLDKEKCCGVPLIANGFHK
KAQKNAEFNVANLEAAIERQDVPILSTSSTCSFTLQQEYPHVLDVDNTKVAKKIEYVTRFLLKEIMNGRGPKMKPLNKKI
VYHTPCHLERSGGNIYTIELLRAIPGLEVQVLDSECCGLAGTYGFKTENYETSVAIGKNIFDKIKAAKPDYAITDCETCK
WQIEENTNTTTIHPISLLCEALI

Sequences:

>Translated_423_residues
MSSPLFKSSFLKDSVLKDNLIFRAPANTSFDQCLKCTVCTVYCPVAKENPDYPGPKQCGPDGERLRFKSPEYYDETLKLC
TNCKRCETACPSGVKIGDMIAVARGKYGKPAYNMKGLRDFVLSHTDLFGSIATPVAPVVNAVTSVPLVKKVMHKTIGVHD
HKSLPKYSHGTFRKWYKKEVNDQSVFERQVHYFHGCFVNYNHPQLGKDFIKVMNNMNIGVQLLDKEKCCGVPLIANGFHK
KAQKNAEFNVANLEAAIERQDVPILSTSSTCSFTLQQEYPHVLDVDNTKVAKKIEYVTRFLLKEIMNGRGPKMKPLNKKI
VYHTPCHLERSGGNIYTIELLRAIPGLEVQVLDSECCGLAGTYGFKTENYETSVAIGKNIFDKIKAAKPDYAITDCETCK
WQIEENTNTTTIHPISLLCEALI
>Mature_422_residues
SSPLFKSSFLKDSVLKDNLIFRAPANTSFDQCLKCTVCTVYCPVAKENPDYPGPKQCGPDGERLRFKSPEYYDETLKLCT
NCKRCETACPSGVKIGDMIAVARGKYGKPAYNMKGLRDFVLSHTDLFGSIATPVAPVVNAVTSVPLVKKVMHKTIGVHDH
KSLPKYSHGTFRKWYKKEVNDQSVFERQVHYFHGCFVNYNHPQLGKDFIKVMNNMNIGVQLLDKEKCCGVPLIANGFHKK
AQKNAEFNVANLEAAIERQDVPILSTSSTCSFTLQQEYPHVLDVDNTKVAKKIEYVTRFLLKEIMNGRGPKMKPLNKKIV
YHTPCHLERSGGNIYTIELLRAIPGLEVQVLDSECCGLAGTYGFKTENYETSVAIGKNIFDKIKAAKPDYAITDCETCKW
QIEENTNTTTIHPISLLCEALI

Specific function: Electron transfer protein; may also function as the membrane anchor for the glpAB dimer [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=Loosely bound to the cytoplasmic membrane often occurring in vesicles associated with fumarate reductase [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1788576, Length=396, Percent_Identity=57.5757575757576, Blast_Score=494, Evalue=1e-141,
Organism=Escherichia coli, GI48994913, Length=424, Percent_Identity=25, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786497, Length=223, Percent_Identity=26.9058295964126, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR004017
- InterPro:   IPR012285
- InterPro:   IPR017753
- InterPro:   IPR009051 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: NA

Molecular weight: Translated: 47427; Mature: 47296

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPLFKSSFLKDSVLKDNLIFRAPANTSFDQCLKCTVCTVYCPVAKENPDYPGPKQCGP
CCCCCCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHEEEEEEECCCCCCCCCCCCCCCCC
DGERLRFKSPEYYDETLKLCTNCKRCETACPSGVKIGDMIAVARGKYGKPAYNMKGLRDF
CCCCEEECCCHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHEECCCCCCCCCCCHHHHHHH
VLSHTDLFGSIATPVAPVVNAVTSVPLVKKVMHKTIGVHDHKSLPKYSHGTFRKWYKKEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHC
NDQSVFERQVHYFHGCFVNYNHPQLGKDFIKVMNNMNIGVQLLDKEKCCGVPLIANGFHK
CHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHCCHHH
KAQKNAEFNVANLEAAIERQDVPILSTSSTCSFTLQQEYPHVLDVDNTKVAKKIEYVTRF
HHHCCCCCCHHHHHHHHHHCCCCEEECCCCEEEEECCCCCCEEECCCHHHHHHHHHHHHH
LLKEIMNGRGPKMKPLNKKIVYHTPCHLERSGGNIYTIELLRAIPGLEVQVLDSECCGLA
HHHHHHCCCCCCCCCCCCEEEEECCCEEECCCCCEEEEEHHHHCCCCEEEEECCHHCCCC
GTYGFKTENYETSVAIGKNIFDKIKAAKPDYAITDCETCKWQIEENTNTTTIHPISLLCE
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEECCCCCEEECHHHHHHH
ALI
HHC
>Mature Secondary Structure 
SSPLFKSSFLKDSVLKDNLIFRAPANTSFDQCLKCTVCTVYCPVAKENPDYPGPKQCGP
CCCCCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHEEEEEEECCCCCCCCCCCCCCCCC
DGERLRFKSPEYYDETLKLCTNCKRCETACPSGVKIGDMIAVARGKYGKPAYNMKGLRDF
CCCCEEECCCHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHEECCCCCCCCCCCHHHHHHH
VLSHTDLFGSIATPVAPVVNAVTSVPLVKKVMHKTIGVHDHKSLPKYSHGTFRKWYKKEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHC
NDQSVFERQVHYFHGCFVNYNHPQLGKDFIKVMNNMNIGVQLLDKEKCCGVPLIANGFHK
CHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHCCHHH
KAQKNAEFNVANLEAAIERQDVPILSTSSTCSFTLQQEYPHVLDVDNTKVAKKIEYVTRF
HHHCCCCCCHHHHHHHHHHCCCCEEECCCCEEEEECCCCCCEEECCCHHHHHHHHHHHHH
LLKEIMNGRGPKMKPLNKKIVYHTPCHLERSGGNIYTIELLRAIPGLEVQVLDSECCGLA
HHHHHHCCCCCCCCCCCCEEEEECCCEEECCCCCEEEEEHHHHCCCCEEEEECCHHCCCC
GTYGFKTENYETSVAIGKNIFDKIKAAKPDYAITDCETCKWQIEENTNTTTIHPISLLCE
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEECCCCCEEECHHHHHHH
ALI
HHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: FAD; glycerol-3-phosphate [C]

Specific reaction: FAD + glycerol-3-phosphate = FADH2 + dihydroxy-acetone-phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]