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The map label for this gene is chuR [H]

Identifier: 59713391

GI number: 59713391

Start: 230046

End: 231212

Strand: Reverse

Name: chuR [H]

Synonym: VF_A0208

Alternate gene names: 59713391

Gene position: 231212-230046 (Counterclockwise)

Preceding gene: 59713396

Following gene: 59713390

Centisome position: 17.38

GC content: 36.16

Gene sequence:

>1167_bases
ATGACAGAACAGTTAGCAGCTACATCAACACCATATAGTTTATTTATTAAAGCTGAAAGTGCGAGATGCAACCTAGATTG
TCATTACTGTTATTACCTGAAAAATGAAGACAAAAGCAAACCAGGAATGGATGCAGAAACACTAGATAAACTGGTTTCTA
ATCATATTCAATCTCAACCACCACAAATACCTGTTATTGATTTTATTTGGCATGGTGGAGAGCCAATGATGAAAGGGTTA
GCTTTTTATCAAACCGCAATAGAACTTCAACAAGCACATCAATCGACAACTCCAATCCAAAATACAATTCAAACCAATGG
CACCCTAATTAATGAACGTTGGGCAGCTTTCTTTGCCCAACATAATTTTATGGTAGGGATCAGTATCGATGGGCCACAAC
TGATTAATGATATTGCTCGAATTGATAAAGCGGGTAACTCCTCTTTTGAACGAACCATGCGTGGCATACAGCACTTAAAA
CAACAGAACGTTGAATTTAATACACTCACGGTTATCAATAATAAAAGCTATAAGCATGGCAAAGCTATTTATCGATTTTT
AAAAGAGAATGGCAGCACTTATCTGCAATTTCAGCCATGTATTGACCATGAAATGGATCGTCGCTTTGATTACGATTGGA
CTTTGACTGGTAAACAATGGGGAGAATTCTTATGCAATGTTTTTGATGAATGGGCAGCTAACGATATTGGTAAGATTTAT
GTTCAATTCTTTGAAAACTGCTTAATGATCTTAATGGGTCATCAAAGCCAAATGTGCCACCATGCAGAAACTTGCGGTCA
ACAATTAATGATAGAATCTAACGGTGACGTTTTTAGTTGTGACCATTACGCCTATAACAACTATAAAATAGGCAATATCA
ATGATAATAATGCCTCTTTAGCACAGATGGCTAACTCACCAGAGCAAATGCTATTTGGGCAAAATAAACACGATTCACTG
AATCAAAAATGCTTTCGTTGTGATTTTAAACCCTTGTGTAATGGTGGATGTCCTAAAAACAGAGTAGATAAAATCAATAA
TGGTGAAAACCATAATGTTCTGTGTGAAGGTTATGAACTTTTTTTTAAACACGCCTTACCAACAATGCTCAAAATGGTAG
ATGCAATGAAGCAAGGTTACTCTCCCATTCATTACCCTATGTTTTAG

Upstream 100 bases:

>100_bases
AAAGAATGAATATCCTCTATTAAAAAATGCAATTCGACTATATAAGAGGAATTCATTAAATTAATAAGTGTCAGCAATGA
TCATTTAATGAGGAACAATA

Downstream 100 bases:

>100_bases
GAAAATTAATTACATTCAACACAACTCAAGTTTATATACCATACTTAGTATTAACGACAATCACTTACGGATGAGTGTTG
AATGCTAAAGTGTCCATCAA

Product: arylsulfatase regulator (Fe-S oxidoreductase)

Products: NA

Alternate protein names: AnSME; Chondroitin sulfate/heparin utilization regulation protein; Ser-type sulfatase-activating enzyme [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MTEQLAATSTPYSLFIKAESARCNLDCHYCYYLKNEDKSKPGMDAETLDKLVSNHIQSQPPQIPVIDFIWHGGEPMMKGL
AFYQTAIELQQAHQSTTPIQNTIQTNGTLINERWAAFFAQHNFMVGISIDGPQLINDIARIDKAGNSSFERTMRGIQHLK
QQNVEFNTLTVINNKSYKHGKAIYRFLKENGSTYLQFQPCIDHEMDRRFDYDWTLTGKQWGEFLCNVFDEWAANDIGKIY
VQFFENCLMILMGHQSQMCHHAETCGQQLMIESNGDVFSCDHYAYNNYKIGNINDNNASLAQMANSPEQMLFGQNKHDSL
NQKCFRCDFKPLCNGGCPKNRVDKINNGENHNVLCEGYELFFKHALPTMLKMVDAMKQGYSPIHYPMF

Sequences:

>Translated_388_residues
MTEQLAATSTPYSLFIKAESARCNLDCHYCYYLKNEDKSKPGMDAETLDKLVSNHIQSQPPQIPVIDFIWHGGEPMMKGL
AFYQTAIELQQAHQSTTPIQNTIQTNGTLINERWAAFFAQHNFMVGISIDGPQLINDIARIDKAGNSSFERTMRGIQHLK
QQNVEFNTLTVINNKSYKHGKAIYRFLKENGSTYLQFQPCIDHEMDRRFDYDWTLTGKQWGEFLCNVFDEWAANDIGKIY
VQFFENCLMILMGHQSQMCHHAETCGQQLMIESNGDVFSCDHYAYNNYKIGNINDNNASLAQMANSPEQMLFGQNKHDSL
NQKCFRCDFKPLCNGGCPKNRVDKINNGENHNVLCEGYELFFKHALPTMLKMVDAMKQGYSPIHYPMF
>Mature_387_residues
TEQLAATSTPYSLFIKAESARCNLDCHYCYYLKNEDKSKPGMDAETLDKLVSNHIQSQPPQIPVIDFIWHGGEPMMKGLA
FYQTAIELQQAHQSTTPIQNTIQTNGTLINERWAAFFAQHNFMVGISIDGPQLINDIARIDKAGNSSFERTMRGIQHLKQ
QNVEFNTLTVINNKSYKHGKAIYRFLKENGSTYLQFQPCIDHEMDRRFDYDWTLTGKQWGEFLCNVFDEWAANDIGKIYV
QFFENCLMILMGHQSQMCHHAETCGQQLMIESNGDVFSCDHYAYNNYKIGNINDNNASLAQMANSPEQMLFGQNKHDSLN
QKCFRCDFKPLCNGGCPKNRVDKINNGENHNVLCEGYELFFKHALPTMLKMVDAMKQGYSPIHYPMF

Specific function: Involved in 'Ser-type' sulfatase maturation under anaerobic conditions. Links the heparin and the chondroitin sulfate utilization pathways which contribute to the colonization of the intestinal tract. May catalyze the activation of chondro-6- sulfatase, i

COG id: COG0641

COG function: function code R; Arylsulfatase regulator (Fe-S oxidoreductase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family [H]

Homologues:

Organism=Escherichia coli, GI48994973, Length=389, Percent_Identity=35.4755784061697, Blast_Score=282, Evalue=3e-77,
Organism=Escherichia coli, GI87081923, Length=383, Percent_Identity=38.9033942558747, Blast_Score=276, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 44552; Mature: 44421

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQLAATSTPYSLFIKAESARCNLDCHYCYYLKNEDKSKPGMDAETLDKLVSNHIQSQP
CCCCCCCCCCCEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCC
PQIPVIDFIWHGGEPMMKGLAFYQTAIELQQAHQSTTPIQNTIQTNGTLINERWAAFFAQ
CCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEEHHHHHHHHHH
HNFMVGISIDGPQLINDIARIDKAGNSSFERTMRGIQHLKQQNVEFNTLTVINNKSYKHG
CCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHH
KAIYRFLKENGSTYLQFQPCIDHEMDRRFDYDWTLTGKQWGEFLCNVFDEWAANDIGKIY
HHHHHHHHHCCCEEEEEECCCCCHHHCCCCCCEEECHHHHHHHHHHHHHHHHCCHHHHHH
VQFFENCLMILMGHQSQMCHHAETCGQQLMIESNGDVFSCDHYAYNNYKIGNINDNNASL
HHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEECCCCEEEECCEEECCEEECCCCCCCHHH
AQMANSPEQMLFGQNKHDSLNQKCFRCDFKPLCNGGCPKNRVDKINNGENHNVLCEGYEL
HHHHCCCHHHHCCCCCCCHHHHHHHHCCCHHHCCCCCCCHHHCCCCCCCCCCEEEHHHHH
FFKHALPTMLKMVDAMKQGYSPIHYPMF
HHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TEQLAATSTPYSLFIKAESARCNLDCHYCYYLKNEDKSKPGMDAETLDKLVSNHIQSQP
CCCCCCCCCCEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCC
PQIPVIDFIWHGGEPMMKGLAFYQTAIELQQAHQSTTPIQNTIQTNGTLINERWAAFFAQ
CCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEEHHHHHHHHHH
HNFMVGISIDGPQLINDIARIDKAGNSSFERTMRGIQHLKQQNVEFNTLTVINNKSYKHG
CCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHH
KAIYRFLKENGSTYLQFQPCIDHEMDRRFDYDWTLTGKQWGEFLCNVFDEWAANDIGKIY
HHHHHHHHHCCCEEEEEECCCCCHHHCCCCCCEEECHHHHHHHHHHHHHHHHCCHHHHHH
VQFFENCLMILMGHQSQMCHHAETCGQQLMIESNGDVFSCDHYAYNNYKIGNINDNNASL
HHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEECCCCEEEECCEEECCEEECCCCCCCHHH
AQMANSPEQMLFGQNKHDSLNQKCFRCDFKPLCNGGCPKNRVDKINNGENHNVLCEGYEL
HHHHCCCHHHHCCCCCCCHHHHHHHHCCCHHHCCCCCCCHHHCCCCCCCCCCEEEHHHHH
FFKHALPTMLKMVDAMKQGYSPIHYPMF
HHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1429442; 12663928 [H]