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The map label for this gene is torZ [H]

Identifier: 59713371

GI number: 59713371

Start: 210078

End: 212531

Strand: Reverse

Name: torZ [H]

Synonym: VF_A0188

Alternate gene names: 59713371

Gene position: 212531-210078 (Counterclockwise)

Preceding gene: 59713372

Following gene: 59713363

Centisome position: 15.98

GC content: 42.5

Gene sequence:

>2454_bases
ATGACTAACATTTCTCGTCGCGGCTTTTTAAAAGGCGCAGGTGCATCAGCAGGTGCACTAGCGATTACGTCTATCGCTCC
TTTATCTGTTAATGCCGCTACCGCTGGTCGCACAGATTCATTGGTTTTAACTGCTGGTCGCATGGGCCCATTACTTTGTG
AAGTAAACGATGGCGAGCTACTATCAACCAAAAGTGGTTTAGCTCAGACCGTACCTAATAGCTTACAACAAACGGGACCA
TCGCAAGTTTATACAAAAGCTCGTGTAAAATACCCAATGGTTCGTAAAGGTTATTTAGAAAACCCAAGCAACCCTCAAGG
TGTTCGAGGCAGTGATGAATTTGTACGTGTTTCATGGGATGAAGCATACAAACTAATTCACGAACAGCACATGCGTATTC
GAAAAGAAAACGGACCTGAGTCTATTTTTGCTGGCTCTTACGGTTGGCGTTCAAGTGGTGTATTACATAAAGCACAAACA
CTACTGCAACGTTACATGAGTATGTCTGGTGGTTATGCTGGTCACTTAGGCGATTACTCAACAGGTGCAGCTCAAGTTAT
CATGCCACACGTTGTTGGTTCTATCGAAGTATATGAACAACAAACTACTTATCCTGTTATTTTAGAAAACAGTGAAGTGG
TTGTGTTATGGGGTCTAAACCCATTAAACACACTAAAAATTGCATGGTCTTCAACAGACGGGCAAGGCCTTGAGTTTTTC
CATCAACTGAAAAAATCAGGCAAAACCATCATCATTATTGACCCAATGCGTTCAGAAACTGCTGAATTCTTTGGTGATAA
TGCACAATGGATTGCACCGAACCCACAATCAGATGTGGCAATGATGATGGGTATCGCTCATCAATTAGTTAAAACACAGC
AGCACGATACTGAATTCCTTTCTAAGTACACTGTGGGCTTCGAGCAATTTGAAACTTACTTAATGGGTAAAGAAGACGGT
ATTGAGAAATCACCACAATGGGCAGAAGCGATTTGTGGCGTACCAGCAAAACAGATGGAATTGCTGGCTAAGATCTTCAA
AGAAAACCGCACGATGCTTATGGCTGGTTGGGGTATGCAACGTCAACAACATGGTGAACAACGTCACTGGATGCTAACCG
TTCTTGCTTCTATGCTTGGTCAAGTTGGACTACCGGGCGGTGGTTTTGGTTACTCATACCACTACTCTAATGGTGGTAAC
CCAACACGTGATGCAGGTGTATTACCAGCAATGTCAGCGTCATTAGGCGGTGGCTCATCAGCAGGTAACGATTGGGCAGT
TCAAGGTTCAGTAACGGCTTTCCCTGTTGCGCGTATTGTTGAATGTTTAGAAAAACCGGGAACTCAATATCAACACAATG
GCCATACATTAACTTTCCCTGAGTTAAAAATGATTTGGTGGGCAGGCGGTGCAAACTTTACACATCACCAAGATACCAAC
CGTTTGATTAAAGCGTGGCAAAAACCTGAACTGATCGTTATTTCAGAACCATATTGGACTGCTGCTGCAAAGCATGCGGA
TATCGTTCTTCCAATCACTACCTCATTTGAGCGTAATGACATGACGATGACAGGTGACTACTCTAACCAACACCTAGTTC
CAATGAAACAAGTTGTTGAGCCACAACATGAAGCACGTAACGATTTAGATGTTTTCGCAGATATGGCTGAACATTTAAAA
CCAGGTGGTCGTAATGTATATATGGAAAATAAAACGGAGATGGAATGGCTTCGTGATTTCTATAAAGCAGCTCAAAAAGG
TGGACGAAACGCACGTGTTCCAATGATGAATTTCACTAAGTTCTGGGAAGCAAACCAACTTATCGAAATGAAATGGAACG
CAAAGAATGCCGAGTTTGTTCGTTTTGGTGACTTCCGTAAAGATCCAATCATGAATCCACTAGGTACACCAAGTGGTAAA
ATTGAGATCTTCTCAAAAACCATCGAAGGCTTTAAGTTAGATGATTGTCCTCCACACCCTGTATGGATGGAACCAACAGA
ATGGATGTTCAACTACACCGATGGCGAACTTCAATTAATGACGTCGCACTCTGCTCATCGTTTACACAGCCAATTTAACT
ATGCTGATCTTCGTAAAGAGTATGCAATCCAAGATCGTGAACCAATTACGATTCACCCAGAAGATGCTAAAGCTCGTGGT
ATTAAAGATGGCGACTTAGTTCGTGCTTACAACCAACGTGGGCAAGTTTTGGTTGGTGCTCATGTTTCTGATGGCATCAA
AAAAGGCAGTGTATGTATCCATGAAGGTGCATGGCCTGACTTAGATCCTAAAACAGGTATGTGTAAAAACGGTGGTCCAA
ACGTATTAACTATGGATATACCAACATCACGTCTAGGTAACGGTAACTGTGGTAATTCTGGTGTTGTGAAAATTGAAAAA
TTCACAGGTGTTGCACCAACATTAACGGCGTTTACCCCACCAATGAATGGGTAA

Upstream 100 bases:

>100_bases
TGCACGTACTGATATATCAGCACTGAACCTAGAAATCCTAACTAAATTCTTCCAAAACCACGCTAAAGACGTGGCTAATC
ACAAATAAGAGAGAGTGACT

Downstream 100 bases:

>100_bases
TCCCAATATCATTCATAGAATGGGATAAGCATTCATTTCTTATAAAAAAAGCGCTCTATATTTAGAGCGCTTTGCTTTAT
TTACAGCTAGCCAGCTATTG

Product: TMAO reductase III (TorYZ), TorZ subunit

Products: NA

Alternate protein names: TMAO reductase 2; Trimethylamine oxidase 2 [H]

Number of amino acids: Translated: 817; Mature: 816

Protein sequence:

>817_residues
MTNISRRGFLKGAGASAGALAITSIAPLSVNAATAGRTDSLVLTAGRMGPLLCEVNDGELLSTKSGLAQTVPNSLQQTGP
SQVYTKARVKYPMVRKGYLENPSNPQGVRGSDEFVRVSWDEAYKLIHEQHMRIRKENGPESIFAGSYGWRSSGVLHKAQT
LLQRYMSMSGGYAGHLGDYSTGAAQVIMPHVVGSIEVYEQQTTYPVILENSEVVVLWGLNPLNTLKIAWSSTDGQGLEFF
HQLKKSGKTIIIIDPMRSETAEFFGDNAQWIAPNPQSDVAMMMGIAHQLVKTQQHDTEFLSKYTVGFEQFETYLMGKEDG
IEKSPQWAEAICGVPAKQMELLAKIFKENRTMLMAGWGMQRQQHGEQRHWMLTVLASMLGQVGLPGGGFGYSYHYSNGGN
PTRDAGVLPAMSASLGGGSSAGNDWAVQGSVTAFPVARIVECLEKPGTQYQHNGHTLTFPELKMIWWAGGANFTHHQDTN
RLIKAWQKPELIVISEPYWTAAAKHADIVLPITTSFERNDMTMTGDYSNQHLVPMKQVVEPQHEARNDLDVFADMAEHLK
PGGRNVYMENKTEMEWLRDFYKAAQKGGRNARVPMMNFTKFWEANQLIEMKWNAKNAEFVRFGDFRKDPIMNPLGTPSGK
IEIFSKTIEGFKLDDCPPHPVWMEPTEWMFNYTDGELQLMTSHSAHRLHSQFNYADLRKEYAIQDREPITIHPEDAKARG
IKDGDLVRAYNQRGQVLVGAHVSDGIKKGSVCIHEGAWPDLDPKTGMCKNGGPNVLTMDIPTSRLGNGNCGNSGVVKIEK
FTGVAPTLTAFTPPMNG

Sequences:

>Translated_817_residues
MTNISRRGFLKGAGASAGALAITSIAPLSVNAATAGRTDSLVLTAGRMGPLLCEVNDGELLSTKSGLAQTVPNSLQQTGP
SQVYTKARVKYPMVRKGYLENPSNPQGVRGSDEFVRVSWDEAYKLIHEQHMRIRKENGPESIFAGSYGWRSSGVLHKAQT
LLQRYMSMSGGYAGHLGDYSTGAAQVIMPHVVGSIEVYEQQTTYPVILENSEVVVLWGLNPLNTLKIAWSSTDGQGLEFF
HQLKKSGKTIIIIDPMRSETAEFFGDNAQWIAPNPQSDVAMMMGIAHQLVKTQQHDTEFLSKYTVGFEQFETYLMGKEDG
IEKSPQWAEAICGVPAKQMELLAKIFKENRTMLMAGWGMQRQQHGEQRHWMLTVLASMLGQVGLPGGGFGYSYHYSNGGN
PTRDAGVLPAMSASLGGGSSAGNDWAVQGSVTAFPVARIVECLEKPGTQYQHNGHTLTFPELKMIWWAGGANFTHHQDTN
RLIKAWQKPELIVISEPYWTAAAKHADIVLPITTSFERNDMTMTGDYSNQHLVPMKQVVEPQHEARNDLDVFADMAEHLK
PGGRNVYMENKTEMEWLRDFYKAAQKGGRNARVPMMNFTKFWEANQLIEMKWNAKNAEFVRFGDFRKDPIMNPLGTPSGK
IEIFSKTIEGFKLDDCPPHPVWMEPTEWMFNYTDGELQLMTSHSAHRLHSQFNYADLRKEYAIQDREPITIHPEDAKARG
IKDGDLVRAYNQRGQVLVGAHVSDGIKKGSVCIHEGAWPDLDPKTGMCKNGGPNVLTMDIPTSRLGNGNCGNSGVVKIEK
FTGVAPTLTAFTPPMNG
>Mature_816_residues
TNISRRGFLKGAGASAGALAITSIAPLSVNAATAGRTDSLVLTAGRMGPLLCEVNDGELLSTKSGLAQTVPNSLQQTGPS
QVYTKARVKYPMVRKGYLENPSNPQGVRGSDEFVRVSWDEAYKLIHEQHMRIRKENGPESIFAGSYGWRSSGVLHKAQTL
LQRYMSMSGGYAGHLGDYSTGAAQVIMPHVVGSIEVYEQQTTYPVILENSEVVVLWGLNPLNTLKIAWSSTDGQGLEFFH
QLKKSGKTIIIIDPMRSETAEFFGDNAQWIAPNPQSDVAMMMGIAHQLVKTQQHDTEFLSKYTVGFEQFETYLMGKEDGI
EKSPQWAEAICGVPAKQMELLAKIFKENRTMLMAGWGMQRQQHGEQRHWMLTVLASMLGQVGLPGGGFGYSYHYSNGGNP
TRDAGVLPAMSASLGGGSSAGNDWAVQGSVTAFPVARIVECLEKPGTQYQHNGHTLTFPELKMIWWAGGANFTHHQDTNR
LIKAWQKPELIVISEPYWTAAAKHADIVLPITTSFERNDMTMTGDYSNQHLVPMKQVVEPQHEARNDLDVFADMAEHLKP
GGRNVYMENKTEMEWLRDFYKAAQKGGRNARVPMMNFTKFWEANQLIEMKWNAKNAEFVRFGDFRKDPIMNPLGTPSGKI
EIFSKTIEGFKLDDCPPHPVWMEPTEWMFNYTDGELQLMTSHSAHRLHSQFNYADLRKEYAIQDREPITIHPEDAKARGI
KDGDLVRAYNQRGQVLVGAHVSDGIKKGSVCIHEGAWPDLDPKTGMCKNGGPNVLTMDIPTSRLGNGNCGNSGVVKIEKF
TGVAPTLTAFTPPMNG

Specific function: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions. Can also reduce other N- and S-oxide compounds such as 4-methylmorpholine-N-oxide and biotin sulfoxide (BSO), but with a lower catalytic

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081994, Length=811, Percent_Identity=66.8310727496917, Blast_Score=1146, Evalue=0.0,
Organism=Escherichia coli, GI145693196, Length=774, Percent_Identity=60.9819121447028, Blast_Score=1017, Evalue=0.0,
Organism=Escherichia coli, GI1787231, Length=832, Percent_Identity=40.3846153846154, Blast_Score=597, Evalue=1e-171,
Organism=Escherichia coli, GI87081797, Length=857, Percent_Identity=29.8716452742124, Blast_Score=305, Evalue=8e-84,
Organism=Escherichia coli, GI1787870, Length=866, Percent_Identity=28.175519630485, Blast_Score=263, Evalue=3e-71,
Organism=Escherichia coli, GI171474008, Length=844, Percent_Identity=28.436018957346, Blast_Score=247, Evalue=2e-66,
Organism=Escherichia coli, GI3868721, Length=731, Percent_Identity=22.0246238030096, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1788534, Length=844, Percent_Identity=21.8009478672986, Blast_Score=89, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.7.2.3 [H]

Molecular weight: Translated: 90483; Mature: 90352

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNISRRGFLKGAGASAGALAITSIAPLSVNAATAGRTDSLVLTAGRMGPLLCEVNDGEL
CCCCCCCCCEECCCCCCCEEEEEEECCCEEECCCCCCCCCEEEEECCCCCEEEEECCCCE
LSTKSGLAQTVPNSLQQTGPSQVYTKARVKYPMVRKGYLENPSNPQGVRGSDEFVRVSWD
EECCCCHHHHCCHHHHHCCCHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCEEEEEHH
EAYKLIHEQHMRIRKENGPESIFAGSYGWRSSGVLHKAQTLLQRYMSMSGGYAGHLGDYS
HHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
TGAAQVIMPHVVGSIEVYEQQTTYPVILENSEVVVLWGLNPLNTLKIAWSSTDGQGLEFF
CCHHHHHHHHHHCCEEEEECCCCCEEEECCCCEEEEECCCCCCEEEEEEECCCCCHHHHH
HQLKKSGKTIIIIDPMRSETAEFFGDNAQWIAPNPQSDVAMMMGIAHQLVKTQQHDTEFL
HHHHHCCCEEEEECCCCHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SKYTVGFEQFETYLMGKEDGIEKSPQWAEAICGVPAKQMELLAKIFKENRTMLMAGWGMQ
HHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCC
RQQHGEQRHWMLTVLASMLGQVGLPGGGFGYSYHYSNGGNPTRDAGVLPAMSASLGGGSS
HHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHCCCCCCCC
AGNDWAVQGSVTAFPVARIVECLEKPGTQYQHNGHTLTFPELKMIWWAGGANFTHHQDTN
CCCCEEEECCCHHHHHHHHHHHHHCCCCCEECCCCEEECCCEEEEEEECCCCCCCCCHHH
RLIKAWQKPELIVISEPYWTAAAKHADIVLPITTSFERNDMTMTGDYSNQHLVPMKQVVE
HHHHHCCCCCEEEEECCCHHHHCCCCEEEEEEECCCCCCCCEEECCCCCCCCCCHHHHCC
PQHEARNDLDVFADMAEHLKPGGRNVYMENKTEMEWLRDFYKAAQKGGRNARVPMMNFTK
CHHHHCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
FWEANQLIEMKWNAKNAEFVRFGDFRKDPIMNPLGTPSGKIEIFSKTIEGFKLDDCPPHP
HHCCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCC
VWMEPTEWMFNYTDGELQLMTSHSAHRLHSQFNYADLRKEYAIQDREPITIHPEDAKARG
CCCCCCHHEEEECCCEEEEEECCCHHHHHHCCCHHHHHHHHCCCCCCCEEECCCCHHHCC
IKDGDLVRAYNQRGQVLVGAHVSDGIKKGSVCIHEGAWPDLDPKTGMCKNGGPNVLTMDI
CCCCHHHHHHCCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEC
PTSRLGNGNCGNSGVVKIEKFTGVAPTLTAFTPPMNG
CCCCCCCCCCCCCCEEEEEECCCCCCCCEECCCCCCC
>Mature Secondary Structure 
TNISRRGFLKGAGASAGALAITSIAPLSVNAATAGRTDSLVLTAGRMGPLLCEVNDGEL
CCCCCCCCEECCCCCCCEEEEEEECCCEEECCCCCCCCCEEEEECCCCCEEEEECCCCE
LSTKSGLAQTVPNSLQQTGPSQVYTKARVKYPMVRKGYLENPSNPQGVRGSDEFVRVSWD
EECCCCHHHHCCHHHHHCCCHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCEEEEEHH
EAYKLIHEQHMRIRKENGPESIFAGSYGWRSSGVLHKAQTLLQRYMSMSGGYAGHLGDYS
HHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
TGAAQVIMPHVVGSIEVYEQQTTYPVILENSEVVVLWGLNPLNTLKIAWSSTDGQGLEFF
CCHHHHHHHHHHCCEEEEECCCCCEEEECCCCEEEEECCCCCCEEEEEEECCCCCHHHHH
HQLKKSGKTIIIIDPMRSETAEFFGDNAQWIAPNPQSDVAMMMGIAHQLVKTQQHDTEFL
HHHHHCCCEEEEECCCCHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SKYTVGFEQFETYLMGKEDGIEKSPQWAEAICGVPAKQMELLAKIFKENRTMLMAGWGMQ
HHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCC
RQQHGEQRHWMLTVLASMLGQVGLPGGGFGYSYHYSNGGNPTRDAGVLPAMSASLGGGSS
HHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHCCCCCCCC
AGNDWAVQGSVTAFPVARIVECLEKPGTQYQHNGHTLTFPELKMIWWAGGANFTHHQDTN
CCCCEEEECCCHHHHHHHHHHHHHCCCCCEECCCCEEECCCEEEEEEECCCCCCCCCHHH
RLIKAWQKPELIVISEPYWTAAAKHADIVLPITTSFERNDMTMTGDYSNQHLVPMKQVVE
HHHHHCCCCCEEEEECCCHHHHCCCCEEEEEEECCCCCCCCEEECCCCCCCCCCHHHHCC
PQHEARNDLDVFADMAEHLKPGGRNVYMENKTEMEWLRDFYKAAQKGGRNARVPMMNFTK
CHHHHCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
FWEANQLIEMKWNAKNAEFVRFGDFRKDPIMNPLGTPSGKIEIFSKTIEGFKLDDCPPHP
HHCCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCC
VWMEPTEWMFNYTDGELQLMTSHSAHRLHSQFNYADLRKEYAIQDREPITIHPEDAKARG
CCCCCCHHEEEECCCEEEEEECCCHHHHHHCCCHHHHHHHHCCCCCCCEEECCCCHHHCC
IKDGDLVRAYNQRGQVLVGAHVSDGIKKGSVCIHEGAWPDLDPKTGMCKNGGPNVLTMDI
CCCCHHHHHHCCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEC
PTSRLGNGNCGNSGVVKIEKFTGVAPTLTAFTPPMNG
CCCCCCCCCCCCCCEEEEEECCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]