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The map label for this gene is torY [H]

Identifier: 59713372

GI number: 59713372

Start: 212544

End: 213635

Strand: Reverse

Name: torY [H]

Synonym: VF_A0189

Alternate gene names: 59713372

Gene position: 213635-212544 (Counterclockwise)

Preceding gene: 59713373

Following gene: 59713371

Centisome position: 16.06

GC content: 41.48

Gene sequence:

>1092_bases
ATGAACAAACGCTATATCGCTTTAATCGCTGCTGTCGGTATTGCCATTGGTTGGTTAACCTTTGGCGGTACGCAAGCAGT
TCTCCACGCCACTTCTAGTACTGAGTTTTGTGTTTCATGCCATACAATGGAGAAACCACTGCATGAATATCAAGGTTCCG
TTCATTTTAGTAACCAAAAAGGCATTCGAGCTGAATGTGCAGACTGTCACATTCCTCAAGAACCAATTGATTACTTAATT
ACGAAAATTCGTGCTTCTAAAGACATCTATCATGAATTCGTTACTGGTAAAATTGATACGGATGAAAAATACGAAGAACA
TCGTTTAGCTATGGCTGAAACGGTGTGGGAACAAATGCGTGAAAATGATTCAGCGACATGTCGTTCTTGTCATAGTTTTG
ATGCAATGGAAACCTATGACCAATCAGTAAGCGCACAAAAAATGCACGCTTATGGACAAGAAAACAACCAAACTTGTATC
GACTGCCACAAAGGTGTTGCTCACTTTGCACCTCAAGCTAAATTAGATACGTCTGCATTCGATCATTTATTTGATATGGC
GAAAAACACCAAGCTTGATGCTGAAAAAGTTTACCCTATTGAAAATATTAAGATGTCTGATCTTGCCATCATCAATCCAA
CGGTTGAACTTACAACGGTAAGCGCAAAAGATGAAACTCGCACTGTAACGGTTTCAGGCTTCCAAATGAAAGGGGCTGAA
TCAGTTATTTACATGGGTGAAGGCCAACGTTCAATCATCGCGACGCTAACAGAAAAAGGCATTAAAGCATTAACTCTGGG
TGAAGCAACTACCGATGCTTACGGCAATGAATGGCGCAGCGCCGAGCTAACAGGCACAATCGATGCACCTGTTCTAGCGT
CAAACCAGCCTTTATGGGACTACGCTGAAGAGCTTGATAATGTGTACTGTTCAACATGTCATGCCAAAATTCCAGCAAAT
CACTTCACAGTGAACTCTTGGGGTCCTGTAGCTAAAAGCATGGGTGCACGTACTGATATATCAGCACTGAACCTAGAAAT
CCTAACTAAATTCTTCCAAAACCACGCTAAAGACGTGGCTAATCACAAATAA

Upstream 100 bases:

>100_bases
TTTTGAAATATTTTATTTTTTACTTACATACCATTAACCCCAAAGTGGTAATATTGCGATTGACCACACATAGAATGTGG
CTAAATTAAGGATCATTATT

Downstream 100 bases:

>100_bases
GAGAGAGTGACTATGACTAACATTTCTCGTCGCGGCTTTTTAAAAGGCGCAGGTGCATCAGCAGGTGCACTAGCGATTAC
GTCTATCGCTCCTTTATCTG

Product: TMAO reductase III (TorYZ), cytochrome c-type subunit

Products: H2O; trimethylamine; NAD [C]

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MNKRYIALIAAVGIAIGWLTFGGTQAVLHATSSTEFCVSCHTMEKPLHEYQGSVHFSNQKGIRAECADCHIPQEPIDYLI
TKIRASKDIYHEFVTGKIDTDEKYEEHRLAMAETVWEQMRENDSATCRSCHSFDAMETYDQSVSAQKMHAYGQENNQTCI
DCHKGVAHFAPQAKLDTSAFDHLFDMAKNTKLDAEKVYPIENIKMSDLAIINPTVELTTVSAKDETRTVTVSGFQMKGAE
SVIYMGEGQRSIIATLTEKGIKALTLGEATTDAYGNEWRSAELTGTIDAPVLASNQPLWDYAEELDNVYCSTCHAKIPAN
HFTVNSWGPVAKSMGARTDISALNLEILTKFFQNHAKDVANHK

Sequences:

>Translated_363_residues
MNKRYIALIAAVGIAIGWLTFGGTQAVLHATSSTEFCVSCHTMEKPLHEYQGSVHFSNQKGIRAECADCHIPQEPIDYLI
TKIRASKDIYHEFVTGKIDTDEKYEEHRLAMAETVWEQMRENDSATCRSCHSFDAMETYDQSVSAQKMHAYGQENNQTCI
DCHKGVAHFAPQAKLDTSAFDHLFDMAKNTKLDAEKVYPIENIKMSDLAIINPTVELTTVSAKDETRTVTVSGFQMKGAE
SVIYMGEGQRSIIATLTEKGIKALTLGEATTDAYGNEWRSAELTGTIDAPVLASNQPLWDYAEELDNVYCSTCHAKIPAN
HFTVNSWGPVAKSMGARTDISALNLEILTKFFQNHAKDVANHK
>Mature_363_residues
MNKRYIALIAAVGIAIGWLTFGGTQAVLHATSSTEFCVSCHTMEKPLHEYQGSVHFSNQKGIRAECADCHIPQEPIDYLI
TKIRASKDIYHEFVTGKIDTDEKYEEHRLAMAETVWEQMRENDSATCRSCHSFDAMETYDQSVSAQKMHAYGQENNQTCI
DCHKGVAHFAPQAKLDTSAFDHLFDMAKNTKLDAEKVYPIENIKMSDLAIINPTVELTTVSAKDETRTVTVSGFQMKGAE
SVIYMGEGQRSIIATLTEKGIKALTLGEATTDAYGNEWRSAELTGTIDAPVLASNQPLWDYAEELDNVYCSTCHAKIPAN
HFTVNSWGPVAKSMGARTDISALNLEILTKFFQNHAKDVANHK

Specific function: Part of the anaerobic respiratory chain of trimethylamine-N-oxide reductase TorZ. Required for electron transfer to the TorZ terminal enzyme [H]

COG id: COG3005

COG function: function code C; Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TorC/TorY family [H]

Homologues:

Organism=Escherichia coli, GI1788181, Length=336, Percent_Identity=55.952380952381, Blast_Score=418, Evalue=1e-118,
Organism=Escherichia coli, GI1787230, Length=367, Percent_Identity=33.2425068119891, Blast_Score=212, Evalue=2e-56,
Organism=Escherichia coli, GI1788530, Length=176, Percent_Identity=42.6136363636364, Blast_Score=161, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009154
- InterPro:   IPR011031
- InterPro:   IPR005126 [H]

Pfam domain/function: PF03264 Cytochrom_NNT [H]

EC number: NA

Molecular weight: Translated: 40315; Mature: 40315

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS51008 MULTIHEME_CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKRYIALIAAVGIAIGWLTFGGTQAVLHATSSTEFCVSCHTMEKPLHEYQGSVHFSNQK
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEHHHHHHHHHHHCCCEEECCCC
GIRAECADCHIPQEPIDYLITKIRASKDIYHEFVTGKIDTDEKYEEHRLAMAETVWEQMR
CCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ENDSATCRSCHSFDAMETYDQSVSAQKMHAYGQENNQTCIDCHKGVAHFAPQAKLDTSAF
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHCCCCCCCCHHHH
DHLFDMAKNTKLDAEKVYPIENIKMSDLAIINPTVELTTVSAKDETRTVTVSGFQMKGAE
HHHHHHHHCCCCCHHHCCCCCCCCCCCEEEECCCEEEEEEECCCCCEEEEEECEEECCCC
SVIYMGEGQRSIIATLTEKGIKALTLGEATTDAYGNEWRSAELTGTIDAPVLASNQPLWD
EEEEECCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCEEECCCCHHH
YAEELDNVYCSTCHAKIPANHFTVNSWGPVAKSMGARTDISALNLEILTKFFQNHAKDVA
HHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
NHK
CCC
>Mature Secondary Structure
MNKRYIALIAAVGIAIGWLTFGGTQAVLHATSSTEFCVSCHTMEKPLHEYQGSVHFSNQK
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEHHHHHHHHHHHCCCEEECCCC
GIRAECADCHIPQEPIDYLITKIRASKDIYHEFVTGKIDTDEKYEEHRLAMAETVWEQMR
CCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ENDSATCRSCHSFDAMETYDQSVSAQKMHAYGQENNQTCIDCHKGVAHFAPQAKLDTSAF
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHCCCCCCCCHHHH
DHLFDMAKNTKLDAEKVYPIENIKMSDLAIINPTVELTTVSAKDETRTVTVSGFQMKGAE
HHHHHHHHCCCCCHHHCCCCCCCCCCCEEEECCCEEEEEEECCCCCEEEEEECEEECCCC
SVIYMGEGQRSIIATLTEKGIKALTLGEATTDAYGNEWRSAELTGTIDAPVLASNQPLWD
EEEEECCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCEEECCCCHHH
YAEELDNVYCSTCHAKIPANHFTVNSWGPVAKSMGARTDISALNLEILTKFFQNHAKDVA
HHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
NHK
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: trimethylamine-N-oxide; NADH [C]

Specific reaction: trimethylamine-N-oxide + NADH = H2O + trimethylamine + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]